ENSMUSG00000039321


Mus musculus

Features
Gene ID: ENSMUSG00000039321
  
Biological name :Uts2r
  
Synonyms : Q8VIH9 / urotensin 2 receptor / Uts2r
  
Possible biological names infered from orthology : Q9UKP6
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 121160271
Gene end: 121161973
  
Corresponding Affymetrix probe sets: 10383514 (MoGene1.0st)   1451863_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000046920
NCBI entrez gene - 217369     See in Manteia.
MGI - MGI:2183450
RefSeq - NM_145440
RefSeq Peptide - NP_663415
swissprot - Q05AD1
swissprot - Q8VIH9
Ensembl - ENSMUSG00000039321
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UTS2RENSDARG00000009624Danio rerio
 UTS2RENSGALG00000001626Gallus gallus
 UTS2RENSG00000181408Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000670  Urotensin II receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003013 circulatory system process IBA
 biological_processGO:0003105 negative regulation of glomerular filtration IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007218 neuropeptide signaling pathway IBA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness IEA
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0035811 negative regulation of urine volume IEA
 biological_processGO:0035814 negative regulation of renal sodium excretion IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045776 negative regulation of blood pressure IEA
 biological_processGO:0045777 positive regulation of blood pressure IEA
 biological_processGO:0045907 positive regulation of vasoconstriction IEA
 biological_processGO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep IEA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IEA
 biological_processGO:0097746 regulation of blood vessel diameter IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0001604 urotensin II receptor activity IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000250 abnormal vasoconstriction "anomalous narrowing of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gjc1tm2.1Kni/Gjc1tm2.1Kni
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028963 Uts2 / Q9QZQ3 / urotensin 2 / O95399*  / complex / reaction
 ENSMUSG00000056423 Uts2b / Q765I1 / urotensin 2B / Q765I0*  / reaction / complex






 

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