ENSMUSG00000039329


Mus musculus

Features
Gene ID: ENSMUSG00000039329
  
Biological name :Tex19.1
  
Synonyms : Q99MV2 / Testis-expressed protein 19.1 / Tex19.1
  
Possible biological names infered from orthology : Q8NA77 / testis expressed 19 / TEX19
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 121146143
Gene end: 121148319
  
Corresponding Affymetrix probe sets: 10383511 (MoGene1.0st)   1417482_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114548
Ensembl peptide - ENSMUSP00000048592
NCBI entrez gene - 73679     See in Manteia.
MGI - MGI:1920929
RefSeq - NM_028602
RefSeq Peptide - NP_082878
swissprot - B7ZCA2
swissprot - Q99MV2
Ensembl - ENSMUSG00000039329
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TEX19ENSG00000182459Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9D5S1 / Tex19.2 / testis expressed gene 19.2 / TEX19* / Q8NA77* / testis expressed 19*ENSMUSG0000003933755


Protein motifs (from Interpro)
Interpro ID Name
 IPR029093  Testis-expressed protein 19


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0001890 placenta development IMP
 biological_processGO:0007129 synapsis IMP
 biological_processGO:0007131 reciprocal meiotic recombination IMP
 biological_processGO:0007140 male meiotic nuclear division IMP
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0008584 male gonad development IMP
 biological_processGO:0010529 negative regulation of transposition IMP
 biological_processGO:0010608 posttranscriptional regulation of gene expression IMP
 biological_processGO:0019953 sexual reproduction IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 biological_processGO:0060720 spongiotrophoblast cell proliferation IMP
 biological_processGO:0060722 cell proliferation involved in embryonic placenta development IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0034584 piRNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Prdm14tm1e(EUCOMM)Wtsi/Prdm14tm1e(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Ahvy/Ahvy
Genetic Background: B6.C3-Bpifa2a Ahvy

Allelic Composition: Tex19.1tm1(rtTA2S*M2,lacZ)Jw/Tex19.1tm1(rtTA2S*M2,lacZ)Jw
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0001154 seminiferous tubule degeneration "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
Show

Allelic Composition: Tex19.1tm2.2Ics/Tex19.1tm2.2Ics,Tex19.2tm1.2Ics/Tex19.2tm1.2Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
Show

Allelic Composition: Myh10ehc/Myh10tm2Rsad
Genetic Background: involves: 129S4/SvJae * 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6J

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Ahvy/Ahvy
Genetic Background: B6.C3-Bpifa2a Ahvy

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0001711 abnormal placenta 
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Ahvy/Ahvy
Genetic Background: B6.C3-Bpifa2a Ahvy

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Ahvy/Ahvy
Genetic Background: B6.C3-Bpifa2a Ahvy

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

Allelic Composition: Tex19.1tm2.2Ics/Tex19.1tm2.2Ics,Tex19.2tm1.2Ics/Tex19.2tm1.2Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0001932 abnormal spermiogenesis "failure of sperm cells to form or differentiate" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ahvy/Ahvy
Genetic Background: B6.C3-Bpifa2a Ahvy

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Myh10ehc/Myh10tm2Rsad
Genetic Background: involves: 129S4/SvJae * 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6J

 MP:0002216 abnormal seminiferous tubule morphology "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ahvy/Ahvy
Genetic Background: B6.C3-Bpifa2a Ahvy

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Ahvy/Ahvy
Genetic Background: B6.C3-Bpifa2a Ahvy

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0003698 abnormal male reproductive system physiology "anomaly in the function of the male organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ahvy/Ahvy
Genetic Background: B6.C3-Bpifa2a Ahvy

 MP:0004179 transmission ratio distortion "the occurence of an allele or haplotype in the offspring of an organism at skewed Mendelian ratios" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tex19.1tm2.2Ics/Tex19.1tm2.2Ics,Tex19.2tm1.2Ics/Tex19.2tm1.2Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0004200 reduced fetal size "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0004259 small placenta "reduced size of the size or shape of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ahvy/Ahvy
Genetic Background: B6.C3-Bpifa2a Ahvy

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

Allelic Composition: Tex19.1tm2.2Ics/Tex19.1tm2.2Ics,Tex19.2tm1.2Ics/Tex19.2tm1.2Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0004901 decreased male germ cell number "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ahvy/Ahvy
Genetic Background: B6.C3-Bpifa2a Ahvy

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

Allelic Composition: Tex19.1tm2.2Ics/Tex19.1tm2.2Ics,Tex19.2tm1.2Ics/Tex19.2tm1.2Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ahvy/Ahvy
Genetic Background: B6.C3-Bpifa2a Ahvy

 MP:0005578 teratozoospermia "presence of malformed spermatozoa in the semen; malformations include the physical bending of the sperm to produce kinks or bends" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Tex19.1tm1(rtTA2S*M2,lacZ)Jw/Tex19.1tm1(rtTA2S*M2,lacZ)Jw
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

Allelic Composition: Tex19.1tm2.2Ics/Tex19.1tm2.2Ics,Tex19.2tm1.2Ics/Tex19.2tm1.2Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ahvy/Ahvy
Genetic Background: B6.C3-Bpifa2a Ahvy

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0008966 abnormal chiasmata formation "atypical contact between nonsister chromatids of homologous chromosomes during meiosis I, precluding formation of the expected number of cross-shaped configurations representing recombination events" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex19.1tm1(rtTA2S*M2,lacZ)Jw/Tex19.1tm1(rtTA2S*M2,lacZ)Jw
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0009431 decreased fetal weight "reduced weight of a fetus compared to controls (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0009452 abnormal synaptonemal complex "an anomaly in the formation of the proteinaceous structure involved in the pairing of homologous chromosomes during first prophase of meiosis" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex19.1tm2.2Ics/Tex19.1tm2.2Ics,Tex19.2tm1.2Ics/Tex19.2tm1.2Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0009674 decreased birth weight "reduction in average weight at birth compared to controls" [RGD:cur "Rat Genome Database submission"]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0009703 decreased birth body size "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Ahvy/Ahvy
Genetic Background: B6.C3-Bpifa2a Ahvy

Allelic Composition: Tex19.1tm1(rtTA2S*M2,lacZ)Jw/Tex19.1tm1(rtTA2S*M2,lacZ)Jw
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0011750 abnormal seminiferous tubule epithelium morphology "any structural anomaly of the stratified epithelial lining of the seminiferous tubules, consisting of the developing spermatozoa and the supporting Sertoli cells, which are tall, columnar type cells that line the tubule" [MGI:csmith]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0013248 placenta junctional zone necrosis "morphological changes resulting from pathological death of placenta junctional zone tissue; usually due to irreversible damage" [MGI:csmith]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0013600 testis degeneration "a retrogressive impairment of function or destruction of either or both of the male reproductive glands" [MGI:Anna]
Show

Allelic Composition: Tex19.1tm2.2Ics/Tex19.1tm2.2Ics,Tex19.2tm1.2Ics/Tex19.2tm1.2Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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