ENSMUSG00000039367


Mus musculus

Features
Gene ID: ENSMUSG00000039367
  
Biological name :Sec24c
  
Synonyms : Sec24c / Sec24 related gene family, member C (S. cerevisiae)
  
Possible biological names infered from orthology : P53992 / SEC24 homolog C, COPII coat complex component
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: A3
Gene start: 20674308
Gene end: 20694852
  
Corresponding Affymetrix probe sets: 10412981 (MoGene1.0st)   1430250_at (Mouse Genome 430 2.0 Array)   1452147_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152917
Ensembl peptide - ENSMUSP00000154291
Ensembl peptide - ENSMUSP00000153455
Ensembl peptide - ENSMUSP00000153434
Ensembl peptide - ENSMUSP00000153317
Ensembl peptide - ENSMUSP00000153039
Ensembl peptide - ENSMUSP00000152990
Ensembl peptide - ENSMUSP00000045955
NCBI entrez gene - 218811     See in Manteia.
MGI - MGI:1919746
RefSeq - XM_006518818
RefSeq - NM_001168273
RefSeq - NM_172596
RefSeq - XM_006518813
RefSeq - XM_006518815
RefSeq - XM_006518816
RefSeq - XM_006518817
RefSeq Peptide - NP_001161745
RefSeq Peptide - NP_766184
swissprot - A0A286YDI8
swissprot - A0A286YD08
swissprot - A0A286YCX0
swissprot - A0A286YCC8
swissprot - G3X972
swissprot - A0A286YDJ8
swissprot - A0A286YDN4
Ensembl - ENSMUSG00000039367
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sec24cENSDARG00000103516Danio rerio
 SEC24CENSGALG00000005181Gallus gallus
 P53992ENSG00000176986Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sec24d / Sec24 related gene family, member D (S. cerevisiae) / O94855* / SEC24 homolog D, COPII coat complex component*ENSMUSG0000003923454
Sec24b / Sec24 related gene family, member B (S. cerevisiae) / O95487* / SEC24 homolog B, COPII coat complex component*ENSMUSG0000000105227
Q3U2P1 / Sec24a / Protein transport protein Sec24A / O95486* / SEC24 homolog A, COPII coat complex component*ENSMUSG0000003639126


Protein motifs (from Interpro)
Interpro ID Name
 IPR006895  Zinc finger, Sec23/Sec24-type
 IPR006896  Sec23/Sec24, trunk domain
 IPR006900  Sec23/Sec24, helical domain
 IPR007123  Gelsolin-like domain
 IPR012990  Sec23/Sec24 beta-sandwich
 IPR029006  ADF-H/Gelsolin-like domain superfamily
 IPR036174  Zinc finger, Sec23/Sec24-type superfamily
 IPR036175  Sec23/Sec24 helical domain superfamily
 IPR036180  Gelsolin-like domain superfamily
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0090110 cargo loading into COPII-coated vesicle ISO
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0030127 COPII vesicle coat IEA
 molecular_functionGO:0000149 SNARE binding ISO
 molecular_functionGO:0008270 zinc ion binding ISO


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
MHC class II antigen presentation
Cargo concentration in the ER
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Meox2tm1(cre)Sor/Meox2+,Sec24ctm1c(EUCOMM)Wtsi/Sec24ctm1c(EUCOMM)Wtsi
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * SJL

Allelic Composition: Sec24ctm1d(EUCOMM)Wtsi/Sec24c+,Sec24dGt(RRT226)Byg/Sec24d+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * C57BL/6N * FVB/N

 MP:0011095 complete embryonic lethality between implantation and placentation "death of all organisms of a given genotype in a population between the point of implantation and the initiation of placentation (Mus: E4.5 to less than E9)" [MGI:csmith]
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Allelic Composition: Meox2tm1(cre)Sor/Meox2+,Sec24ctm1c(EUCOMM)Wtsi/Sec24ctm1c(EUCOMM)Wtsi
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * SJL

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Grhl1tm1Jane/Grhl1tm1Jane,Grhl3tm1Jane/Grhl3tm3.1Jane,Tg(KRT14-cre/ERT)20Efu/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * CD-1

Allelic Composition: Meox2tm1(cre)Sor/Meox2+,Sec24ctm1c(EUCOMM)Wtsi/Sec24ctm1c(EUCOMM)Wtsi
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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