ENSMUSG00000039725


Mus musculus

Features
Gene ID: ENSMUSG00000039725
  
Biological name :Trp53rka
  
Synonyms : transformation related protein 53 regulating kinase A / Trp53rka
  
Possible biological names infered from orthology : Q96S44 / TP53 regulating kinase / TP53RK
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H3
Gene start: 165490110
Gene end: 165493324
  
Corresponding Affymetrix probe sets: 10489719 (MoGene1.0st)   1419682_a_at (Mouse Genome 430 2.0 Array)   1452931_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000045141
NCBI entrez gene - 381406     See in Manteia.
MGI - MGI:1918294
RefSeq - NM_001007581
RefSeq Peptide - NP_001007582
swissprot - Q5U452
Ensembl - ENSMUSG00000039725
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tp53rkENSDARG00000112667Danio rerio
 TP53RKENSGALG00000004469Gallus gallus
 Q96S44ENSG00000172315Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Trp53rkb / Q96S44* / TP53RK* / TP53 regulating kinase*ENSMUSG0000004285498


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR022495  Serine/threonine-protein kinase Bud32


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0070525 tRNA threonylcarbamoyladenosine metabolic process IBA
 cellular_componentGO:0000408 EKC/KEOPS complex IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0002039 p53 binding ISO
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016773 phosphotransferase activity, alcohol group as acceptor IEA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000059552 Trp53 / P02340 / transformation related protein 53 / TP53* / P04637* / tumor protein p53*  / reaction






 

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