ENSMUSG00000059552


Mus musculus

Features
Gene ID: ENSMUSG00000059552
  
Biological name :Trp53
  
Synonyms : P02340 / transformation related protein 53 / Trp53
  
Possible biological names infered from orthology : P04637 / TP53 / tumor protein p53
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B3
Gene start: 69580359
Gene end: 69591873
  
Corresponding Affymetrix probe sets: 10377550 (MoGene1.0st)   1426538_a_at (Mouse Genome 430 2.0 Array)   1427739_a_at (Mouse Genome 430 2.0 Array)   1438808_at (Mouse Genome 430 2.0 Array)   1457623_x_at (Mouse Genome 430 2.0 Array)   1459780_at (Mouse Genome 430 2.0 Array)   1459781_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000005371
Ensembl peptide - ENSMUSP00000104297
Ensembl peptide - ENSMUSP00000104298
Ensembl peptide - ENSMUSP00000127130
NCBI entrez gene - 22059     See in Manteia.
MGI - MGI:98834
RefSeq - XM_006533157
RefSeq - NM_001127233
RefSeq - NM_011640
RefSeq Peptide - NP_001120705
RefSeq Peptide - NP_035770
swissprot - Q549C9
swissprot - I7HIK9
swissprot - Q80ZA1
swissprot - P02340
swissprot - A0A158SIS7
Ensembl - ENSMUSG00000059552
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tp53ENSDARG00000035559Danio rerio
 TP53ENSG00000141510Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Trp73 / Q9JJP2 / transformation related protein 73 / TP73* / O15350* / tumor protein p73*ENSMUSG0000002902639
Trp63 / O88898 / transformation related protein 63 / TP63* / Q9H3D4* / tumor protein p63*ENSMUSG0000002251038


Protein motifs (from Interpro)
Interpro ID Name
 IPR002117  p53 tumour suppressor family
 IPR008967  p53-like transcription factor, DNA-binding
 IPR010991  p53, tetramerisation domain
 IPR011615  p53, DNA-binding domain
 IPR012346  p53/RUNT-type transcription factor, DNA-binding domain superfamily
 IPR013872  p53 transactivation domain
 IPR036674  p53-like tetramerisation domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000060 protein import into nucleus, translocation IDA
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0000733 DNA strand renaturation IEA
 biological_processGO:0001701 in utero embryonic development IGI
 biological_processGO:0001756 somitogenesis IGI
 biological_processGO:0001836 release of cytochrome c from mitochondria IGI
 biological_processGO:0002309 T cell proliferation involved in immune response IGI
 biological_processGO:0002326 B cell lineage commitment IMP
 biological_processGO:0002360 T cell lineage commitment IMP
 biological_processGO:0002687 positive regulation of leukocyte migration IEA
 biological_processGO:0002931 response to ischemia IMP
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0006302 double-strand break repair IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest IEA
 biological_processGO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0006983 ER overload response IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IGI
 biological_processGO:0007265 Ras protein signal transduction IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007369 gastrulation IGI
 biological_processGO:0007406 negative regulation of neuroblast proliferation IGI
 biological_processGO:0007417 central nervous system development IGI
 biological_processGO:0007507 heart development IGI
 biological_processGO:0007568 aging IEA
 biological_processGO:0007569 cell aging IEA
 biological_processGO:0007623 circadian rhythm IEP
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0008156 negative regulation of DNA replication IMP
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008340 determination of adult lifespan IMP
 biological_processGO:0009299 mRNA transcription IEA
 biological_processGO:0009303 rRNA transcription IGI
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0009651 response to salt stress IGI
 biological_processGO:0009792 embryo development ending in birth or egg hatching IGI
 biological_processGO:0010035 response to inorganic substance IEA
 biological_processGO:0010038 response to metal ion IEA
 biological_processGO:0010165 response to X-ray IEA
 biological_processGO:0010224 response to UV-B IEA
 biological_processGO:0010243 response to organonitrogen compound IEA
 biological_processGO:0010332 response to gamma radiation IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010629 negative regulation of gene expression IGI
 biological_processGO:0010666 positive regulation of cardiac muscle cell apoptotic process IMP
 biological_processGO:0012501 programmed cell death IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0021549 cerebellum development IDA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0030330 DNA damage response, signal transduction by p53 class mediator IEA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0031000 response to caffeine IEA
 biological_processGO:0031065 positive regulation of histone deacetylation IDA
 biological_processGO:0031497 chromatin assembly IEA
 biological_processGO:0031571 mitotic G1 DNA damage checkpoint IEA
 biological_processGO:0032461 positive regulation of protein oligomerization IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0033077 T cell differentiation in thymus IGI
 biological_processGO:0033552 response to vitamin B3 IEA
 biological_processGO:0034097 response to cytokine IEA
 biological_processGO:0034103 regulation of tissue remodeling IMP
 biological_processGO:0034605 cellular response to heat IEA
 biological_processGO:0034613 cellular protein localization ISO
 biological_processGO:0034614 cellular response to reactive oxygen species IEA
 biological_processGO:0034644 cellular response to UV IEA
 biological_processGO:0035264 multicellular organism growth IGI
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0035794 positive regulation of mitochondrial membrane permeability IGI
 biological_processGO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress IDA
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0042127 regulation of cell proliferation IMP
 biological_processGO:0042149 cellular response to glucose starvation IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043153 entrainment of circadian clock by photoperiod IMP
 biological_processGO:0043200 response to amino acid IEA
 biological_processGO:0043504 mitochondrial DNA repair IMP
 biological_processGO:0043523 regulation of neuron apoptotic process IGI
 biological_processGO:0043525 positive regulation of neuron apoptotic process IMP
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045787 positive regulation of cell cycle IEA
 biological_processGO:0045861 negative regulation of proteolysis IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly IEA
 biological_processGO:0045930 negative regulation of mitotic cell cycle IGI
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046677 response to antibiotic IEA
 biological_processGO:0048147 negative regulation of fibroblast proliferation IEA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0048512 circadian behavior IMP
 biological_processGO:0048568 embryonic organ development IGI
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IMP
 biological_processGO:0050821 protein stabilization IGI
 biological_processGO:0051123 RNA polymerase II transcriptional preinitiation complex assembly IEA
 biological_processGO:0051262 protein tetramerization IEA
 biological_processGO:0051276 chromosome organization IGI
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0051402 neuron apoptotic process IMP
 biological_processGO:0051453 regulation of intracellular pH IEA
 biological_processGO:0051726 regulation of cell cycle IMP
 biological_processGO:0051974 negative regulation of telomerase activity IEA
 biological_processGO:0055093 response to hyperoxia IEA
 biological_processGO:0060333 interferon-gamma-mediated signaling pathway IMP
 biological_processGO:0060411 cardiac septum morphogenesis IGI
 biological_processGO:0061419 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia IMP
 biological_processGO:0065003 protein-containing complex assembly IEA
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IMP
 biological_processGO:0070243 regulation of thymocyte apoptotic process IGI
 biological_processGO:0070245 positive regulation of thymocyte apoptotic process IMP
 biological_processGO:0070266 necroptotic process IGI
 biological_processGO:0071158 positive regulation of cell cycle arrest IEA
 biological_processGO:0071417 cellular response to organonitrogen compound IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:0071479 cellular response to ionizing radiation IEA
 biological_processGO:0071480 cellular response to gamma radiation IEA
 biological_processGO:0071494 cellular response to UV-C IGI
 biological_processGO:0071850 mitotic cell cycle arrest IDA
 biological_processGO:0072331 signal transduction by p53 class mediator IEA
 biological_processGO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator IEA
 biological_processGO:0072363 regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter IMP
 biological_processGO:0072717 cellular response to actinomycin D IEA
 biological_processGO:0090200 positive regulation of release of cytochrome c from mitochondria IEA
 biological_processGO:0090343 positive regulation of cell aging IMP
 biological_processGO:0090399 replicative senescence IEA
 biological_processGO:0090403 oxidative stress-induced premature senescence IEA
 biological_processGO:0097252 oligodendrocyte apoptotic process IEA
 biological_processGO:1900119 positive regulation of execution phase of apoptosis IEA
 biological_processGO:1901525 negative regulation of mitophagy IMP
 biological_processGO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process IGI
 biological_processGO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator IMP
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II IEA
 biological_processGO:1903205 regulation of hydrogen peroxide-induced cell death IEA
 biological_processGO:1904024 negative regulation of glucose catabolic process to lactate via pyruvate IMP
 biological_processGO:1990144 intrinsic apoptotic signaling pathway in response to hypoxia IMP
 biological_processGO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress IMP
 biological_processGO:2000269 regulation of fibroblast apoptotic process IGI
 biological_processGO:2000279 negative regulation of DNA biosynthetic process IEA
 biological_processGO:2000378 negative regulation of reactive oxygen species metabolic process IMP
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process IEA
 biological_processGO:2000772 regulation of cellular senescence IGI
 biological_processGO:2001244 positive regulation of intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005657 replication fork IDA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005669 transcription factor TFIID complex IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0035861 site of double-strand break IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0000990 transcription factor activity, core RNA polymerase binding IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001074 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding involved in preinitiation complex assembly IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IGI
 molecular_functionGO:0001084 obsolete transcription factor activity, TFIID-class binding IEA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0001094 TFIID-class transcription factor binding IEA
 molecular_functionGO:0001221 transcription cofactor binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0002039 p53 binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003684 damaged DNA binding IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IEA
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0035033 histone deacetylase regulator activity IDA
 molecular_functionGO:0035035 histone acetyltransferase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0043621 protein self-association IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA
 molecular_functionGO:0051087 chaperone binding IEA
 molecular_functionGO:0051721 protein phosphatase 2A binding IEA
 molecular_functionGO:0097371 MDM2/MDM4 family protein binding IEA
 molecular_functionGO:0097718 disordered domain specific binding IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Oncogene Induced Senescence
DNA Damage/Telomere Stress Induced Senescence
Autodegradation of the E3 ubiquitin ligase COP1
Ub-specific processing proteases
Ovarian tumor domain proteases
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Regulation of TP53 Expression
Regulation of TP53 Activity through Phosphorylation
Regulation of TP53 Degradation
Regulation of TP53 Activity through Acetylation
Regulation of TP53 Activity through Association with Co-factors
Regulation of TP53 Activity through Methylation
PI5P Regulates TP53 Acetylation
G2/M DNA damage checkpoint
G2/M Checkpoints
Stabilization of p53
Transcriptional activation of cell cycle inhibitor p21
The role of GTSE1 in G2/M progression after G2 checkpoint
RUNX3 regulates CDKN1A transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000026 abnormal inner ear morphology "malformation or malfunction of any components of the labyrinth, including the semicircular canals, vestibule and cochlea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0000066 osteoporosis "reduction in bone mass or atrophy of skeletal tissue; may lead to skeletal fragility" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
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Allelic Composition: Atrtm1Ofc/Atrtm1Ofc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0000067 osteopetrosis "excessive formation of dense trabecular bone and excessive calcified cartilage formation; may lead to anemia and extramedullary hematopoiesis " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Trp53tm2.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Fostm1Wag/Fostm1Wag,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0000069 kyphoscoliosis "kyphosis combined with scoliosis" [MGI:CML, J:66943]
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Allelic Composition: Trp53tm2Xu/Trp53tm2Xu,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

 MP:0000088 short mandible "reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0000111 cleft palate "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: Nabp2tm1.2Nfel/Nabp2tm1.2Nfel,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N * SJL

Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0000116 abnormal tooth development "anomalous formation of the teeth" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

 MP:0000130 abnormal cancellous bone morphology "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0000135 reduced cortical bone thickness "thinner than normal superficial layer of compact bone " [J:61509]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Atrtm1Ofc/Atrtm1Ofc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0000162 lordosis "anteriorly convex curvature of the spine, "saddle back" " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:62022]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0000208 decreased hematocrit "less than the average percentage of a volume of a blood sample occupied by red blood cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

 MP:0000221 decreased WBC count "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

Allelic Composition: Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Mdm2tm1Glo/Mdm2+,Trp53tm2Wahl/Trp53tm2Wahl
Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6

 MP:0000222 decreased neutrophil count "fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0000240 extramedullary hematopoiesis "formation and development of blood cells outside the bone marrow, e.g., in the spleen, liver, or lymph nodes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0000259 abnormal vascular development "malformation or aberrant differentiation of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17509]
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Allelic Composition: Rfngtm2.1Tfv/Rfngtm2.1Tfv
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

 MP:0000266 abnormal cardiac morphology "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Odf1tm1Shf/Odf1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0000284 double outlet right ventricle "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0000297 abnormal endocardial cushion morphology "malformation of the mounds of embryonic connective tissue that bulge into the embryonic atrioventricular canal; these mounds eventually fuse to form the valves between the right and left atrioventricular orifices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0000313 abnormal cell death "anomalous cessation of function at the cellular level" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Trp53tm5Tyj/Trp53tm5Tyj
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Att/Trp53tm1Att
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Gnl3tm2.1Rylt/Gnl3tm2.1Rylt,Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6 * CBA

 MP:0000333 decreased bone marrow cell number "decreased number of cells that make up the core cavities of bones when compared to the norm" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

Allelic Composition: Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm2Glo/Trp53tm2Glo
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Mdm2tm1Glo/Mdm2+,Trp53tm1.1Tldo/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * BALB/c * C57BL/6

Allelic Composition: Mdm4tm1Glo/Mdm4+,Trp53tm1.1Tldo/Trp53+
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

Allelic Composition: Rps27lGt(IST11658B7)Tigm/Rps27lGt(IST11658B7)Tigm,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6N

 MP:0000343 altered response to myocardial infarction "change in the physiological response to necrosis of the cardiac tissue, often resulting from the sudden insufficiency of arterial or venous blood supply due to emboli, thrombi or mechanical factors" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NCrj

 MP:0000350 abnormal cell proliferation "anomalous growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Rb1tm1Tyj/Rb1tm2Brn,Rbl1tm1Tyj/Rbl1tm1Tyj,Trp53tm1Brn/Trp53tm1Tyj,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

 MP:0000351 increased cell proliferation "greater than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm2.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm3.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Trp53tm3Wahl/Trp53tm3Wahl
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Ing1Gt(OST206270)Lex/Ing1Gt(OST206270)Lex,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tg(KRT14-cre)8Brn/0,Tg(KRT5-Akt1*)Jmpa/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * DBA/2J * FVB/N

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1.1Dgk
Genetic Background: involves: 129S * 129X1/SvJ * C57BL/6

 MP:0000352 decreased cell proliferation "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Mdm4Gt(VICTR20)7Lex/Mdm4Gt(VICTR20)7Lex,Trp53tm1Wahl/Trp53tm1Wahl
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

Allelic Composition: Gnl3Gt(W223E05)Wrst/Gnl3Gt(W223E05)Wrst,Trp53tm1Tyj/Trp53tm5Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

Allelic Composition: Rad51tm1Hst/Rad51tm1Hst,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0000367 abnormal coat/ hair morphology "anomalous color, structure, growth, or texture of the hair" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Slc25a37tm1.1Kapl/Slc25a37tm1.2Kapl,Speer6-ps1Tg(Alb-cre)21Mgn/?
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * C57BL/6NCr * DBA

 MP:0000373 belly spot "the appearance of a round area of white fur on the belly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Rps7Zma/Rps7+
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

 MP:0000377 abnormal hair follicle "malformed invagination of the epidermis from which the hair shaft develops" [J:65031]
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Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR

 MP:0000416 sparse fur "fur that is significantly less dense" [J:46854]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0000423 delayed hair regrowth "slow initiation and asynchrony of the hair growth cycle (anagen) after catagen phase " [J:61509]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0000427 abnormal hair cycle "aberrant growth or asynchronous timing of the hair growth " [J:65302]
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Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR

 MP:0000428 abnormal craniofacial morphology "anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Twsg1tm1.1Mboc/Twsg1tm1.1Mboc
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0000433 microcephaly "an abnormally small head" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Atrtm1Ofc/Atrtm1Ofc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

 MP:0000438 abnormal skull morphology "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Nabp2tm1.2Nfel/Nabp2tm1.2Nfel,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N * SJL

 MP:0000439 enlarged skull 
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Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Xrcc4tm2.1Fwa/Xrcc4tm2Fwa,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * SJL

 MP:0000468 abnormal esophageal epithelium morphology "malformation of the epithelial layer of the esophagus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

 MP:0000471 abnormal stomach epithelium morphology "malformation of the epithelial layer of the stomach " [tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

 MP:0000496 abnormal small intestine morphology "structural or developmental anomalies of the intestinum tenue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Mdm2tm1Mep/Mdm2tm1.1Mep
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB

 MP:0000512 intestinal ulcer "lesions in the mucous lining of the intestine" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Rb1tm1.1Jyjw/Rb1tm1.1Jyjw,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

 MP:0000527 abnormal kidney development "anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0000558 abnormal tibia morphology "atructural anomaly of the medial and larger of the two bones of the lower leg" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0000569 abnormal digit pigmentation "anomalous coloration of the fingers or toes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Trp53tm1Manf/Trp53tm1Manf
Genetic Background: Not Specified

 MP:0000575 dark foot pads "darker color of the foot pads due to excess pigment" [cml:Cathleen M. Lutz, Mouse Genome Informatics Curator]
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Allelic Composition: Rpl27aSfa/Rpl27a+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

Allelic Composition: Trp53tm1.1Tldo/Trp53+
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

 MP:0000579 abnormal nail morphology "structural or developmental anomaly of any of the thin, horny, translucent plates covering the dorsal surface of the distal end of each terminal phalanx of the digits" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Trim71Gt(XD089)Byg/Trim71Gt(XD089)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0000585 kinked tail "a sharp bend or zig-zag in the tail" [J:61295]
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Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0000598 abnormal liver morphology "malformation or absence of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:23170]
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Allelic Composition: Gt(ROSA)26Sortm2(sb11)Njen/Gt(ROSA)26Sor+,Trp53tm3Tyj/Trp53+,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+,TgTn(sb-T2/Onc)68Dla/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N

 MP:0000599 enlarged liver "larger than average size of the liver" [J:65146]
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Yjc/Trp53tm1Yjc
Genetic Background: B6.129S1-Trp53tm1Yjc

Allelic Composition: Rps27lGt(IST11658B7)Tigm/Rps27lGt(IST11658B7)Tigm,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6N

 MP:0000600 liver hypoplasia "reduced size of liver due to decreased cell number " [J:57631]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0000607 abnormal hepatocyte morphology "malformation of the main structural component of the liver; these are specialized epithelial cells normally organize into interconnected plates called lobules" [J:23170, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Stk11tm1Mmt/Stk11+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ

 MP:0000610 cholestasis "impairment of bile flow due to obstruction in small bile ducts (intrahepatic cholestasis) or obstruction in large bile ducts (extrahepatic cholestasis)" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0000621 salivary adenocarcinoma "malignant neoplasm of the secreting cells of the salivary gland" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Brca1tm1Aash/Brca1tm1Aash,Trp53tm1Brd/Trp53+,Tg(LGB-cre)74Acl/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * CBA

 MP:0000628 abnormal mammary gland development "aberration in the differentiation of the mammary gland during early embryogenesis or during sexual maturity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Brca1tm1Aash/Brca1tm1Aash
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: B6.129S7-Trp53tm1Ldo

 MP:0000630 mammary gland hyperplasia "increased size of mammary gland due to increased cell number" [J:63229]
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Allelic Composition: Chek1tm2.1Sje/Chek1tm2.1Sje,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: FVB

Allelic Composition: Chek1tm2.1Sje/Chek1+,Trp53tm1Brn/Trp53+,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

 MP:0000662 abnormal branching of the mammary ductal tree "anomaly in the development of the channels that secrete milk and direct milk to the nipple" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Tg(MMTV-AURKA)#Cxd/?,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * FVB/N

Allelic Composition: Chek1tm2.1Sje/Chek1+,Trp53tm1Brn/Trp53+,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

 MP:0000689 abnormal spleen morphology "atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:27463]
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Allelic Composition: Trp53tm1Manf/Trp53tm1Manf
Genetic Background: Not Specified

 MP:0000691 enlarged spleen "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1Yjc/Trp53tm1Yjc
Genetic Background: B6.129S1-Trp53tm1Yjc

Allelic Composition: Rps27lGt(IST11658B7)Tigm/Rps27lGt(IST11658B7)Tigm,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6N

 MP:0000692 small spleen "decreased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0000693 spleen hyperplasia "increased cell number in the spleen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33401]
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Allelic Composition: Trp53tm1Thst/Trp53+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Trp53tm1.1Thst/Trp53tm1.1Thst
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Trp53tm1.1Thst/Trp53+
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Trp53tm1Thst/Trp53tm1.1Thst
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Cpt1cGt(XL823)Byg/Cpt1c+,Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0000694 spleen hypoplasia "small size due to reduced cell number in the spleen" [J:43971]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0000696 abnormal Peyer s patches morphology "anomalous structure, development, or cellular make-up of the lymphoid tissue located on the mucosa of the small intestine" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

 MP:0000702 enlarged lymph nodes "lymph nodes of increased size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Rps27lGt(IST11658B7)Tigm/Rps27lGt(IST11658B7)Tigm,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6N

 MP:0000703 abnormal thymus morphology "anomalous structure or development of the primary lymphoid organ; required for immune system development" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55400]
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Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0000706 small thymus "reduced size of the thymus" [J:36561, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:31167]
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Allelic Composition: Mdm2tm1Glo/Mdm2+,Trp53tm2Wahl/Trp53tm2Wahl
Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0000708 thymus hyperplasia "increased cell number in the thymus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33401]
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Allelic Composition: Dcntm1Ioz/Dcntm1Ioz,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

 MP:0000709 enlarged thymus "increased size of thymus" [J:50053]
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Allelic Composition: Dcntm1Ioz/Dcntm1Ioz,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

 MP:0000715 decreased thymocyte number "fewer than expected number of precursors to T cells; these cells are lymphoid cells found in the thymus " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Cops5tm1Rpar/Cops5tm1Rpar,Tg(Lck-cre)548Jxm/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129 * C57BL/6 * CBA * SJL

Allelic Composition: Bbc3tm1Gpz/Bbc3tm1Gpz,Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nop53tm2.1Asuz/Nop53tm2.1Asuz,Tg(Lck-cre)#Jxm/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * CBA

 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Ace2tm1Hira/Y
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S4/SvJae * FVB/N

Allelic Composition: Trp53tm1Elee/Trp53tm1Tyj,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * FVB/N

Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0000746 weakness "state of being infirm or less strong than littermates" [J:45400]
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Allelic Composition: Ptentm1Mro/Ptentm1Mro,Tg(KRT14-cre)8Brn/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * DBA/2J * FVB/N

 MP:0000753 paralysis "loss of power of voluntary movement in a muscle through injury or disease of its nerve supply" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ptentm1Rdp/Pten+,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (C3H/HeJ x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (CAST/EiJ x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (SJL/J x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Ptch1tm1Yy/Ptch1+,Trp53tm1Brd/Trp53+,Tg(BGLAP-cre)1Clem/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/NJ

 MP:0000755 hindlimb paralysis "loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0000762 abnormal tongue morphology "anomalous structure or development of the mobile mass of muscular tissue and surrounding epithelial tissue occupying the cavity of the mouth and forming part of the floor" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

 MP:0000774 reduced brain size "smaller appearance of the brain" [J:35802]
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Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0000780 abnormal corpus callosum morphology "malformation or absence of a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres; it consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0000807 abnormal hippocampus morphology "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0000849 abnormal cerebellum morphology "any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0000851 cerebellum hypoplasia "reduced cell number in the cerebellum" [MGI:CLS, J:45302]
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Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

 MP:0000852 small cerebellum "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524]
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Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm2Glo/Trp53tm2Glo
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000857 abnormal cerebellar foliation "malformation of small offshoots of the cerebellar lobules" [Principles of Neural Science:ISBN 0-8385-8034-3, J:52951]
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Allelic Composition: Nbntm2Zqw/Nbntm2Zqw,Trp53tm1Brd/Trp53+,Tg(Nes-cre)1Wme/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0000864 abnormal vermis "malformation in the narrow middle zone between the two hemispheres of the cerebellum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61509]
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Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Xrcc4tm2.1Fwa/Xrcc4tm2Fwa,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * SJL

 MP:0000865 absent vermis "missing narrow middle zone between the two hemispheres of the cerebellum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]
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Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0000872 abnormal external granule cell layer "malformation of the transient layer of the cerebellar cortex which is composed of the dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0000875 abnormal cerebellar Purkinje cell layer "any malformation or absence of the cell layer that lies just underneath the molecular layer of the cerebellar cortex; it contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer, and candelabrum interneurons are vertically oriented between the Purkinje cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0000877 abnormal Purkinje cell "any structural anomaly of the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex; these inhibitory neurons provide the output of the cerebellar cortex through axons that project into the white matter, and extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells" [J:46140, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm2Glo/Trp53tm2Glo
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000886 abnormal cerebellar granule layer "any malformation or absence of the innermost cortical layer of the cerebellum; contains densly packed small neurons, mostly granule cells with some Golgi cells are found at the outer border" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Nbntm2Zqw/Nbntm2Zqw,Trp53tm1Brd/Trp53+,Tg(Nes-cre)1Wme/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Xrcc4tm2.1Fwa/Xrcc4tm2Fwa,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * SJL

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: Brca2tm1Arge/Brca2tm1Arge,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Allelic Composition: Tfdp1tm1Lili/Tfdp1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Hipk1tm1Hko/Hipk1tm1Hko,Hipk2tm1Hko/Hipk2tm1Hko,Trp53tm2Mok/Trp53+
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Twsg1tm1.1Mboc/Twsg1tm1.1Mboc
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm2.1Snj/Trp53tm2.1Snj
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Pip4k2bGt(Betageo)1Lca/Pip4k2bGt(Betageo)1Lca,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd

Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0000929 open neural tube "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571]
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Allelic Composition: Ptch1tm1.1Bjw/Ptch1tm1.1Bjw
Genetic Background: involves: 129T2/SvEms * C57BL/6J

Allelic Composition: Pax3Sp/Pax3Sp,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL * C57BL/6J * FVB

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Usp7tm2Wgu/Usp7tm2Wgu,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * SJL

Allelic Composition: Pip4k2bGt(Betageo)1Lca/Pip4k2bGt(Betageo)1Lca,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd

 MP:0001106 abnormal Schwann cell "malformed or absent cells which form the insulating myelin sheaths of peripheral axons" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

 MP:0001116 small gonad "reduced size of the testis or the ovary" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
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Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Rad50tm2Jpt/Rad50tm2Jpt,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

Allelic Composition: Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001153 small seminiferous tubules "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844]
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Allelic Composition: Pum1tm1.2Hfl/Pum1tm1.2Hfl,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB

 MP:0001154 seminiferous tubule degeneration "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
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Allelic Composition: Ing2tm1.1Ccha/Ing2tm1.1Ccha,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

Allelic Composition: Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001158 abnormal prostate morphology "mallformed gland in males that secretes part of the seminiferous fluid" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:63764]
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Allelic Composition: Spta1sph-ha/Spta1+
Genetic Background: involves: DBA/1J

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Brn/Trp53+,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2

 MP:0001168 prostate epithelial dysplasia "abnormal development of the prostate epithelium" [J:63764]
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Pdx1-cre)89.1Dam/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 * CBA

 MP:0001175 abnormal lung morphology "malformed organ of respiration" [J:35802]
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Allelic Composition: Braftm1Mmcm/Braf+
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Lejo/Trp53tm1Lejo
Genetic Background: involves: 129

 MP:0001182 lung hemorrhage "bleeding in the respiratory organs" [J:66345]
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Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N

 MP:0001188 hyperpigmentation "excess of pigment in any or all tissues or a part of a tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50311]
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Allelic Composition: Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB

Allelic Composition: Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh,Trp53tm1Brn/Trp53tm1Brn,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Cdkn2atm2.1Nesh/Cdkn2a+,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB

 MP:0001191 abnormal skin condition "anomalous state of the skin" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: KitlSl-5R/KitlSl-5R
Genetic Background: C3H-KitlSl-5R

 MP:0001199 thin skin "reduced thickness of the outer protective layer of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471]
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Allelic Composition: Trp53tm2Xu/Trp53tm2Xu,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

 MP:0001203 skin irradiation sensitivity "increased incidence of aberrant or damaged cells due to irradiation induced genotoxic damage" [J:65162]
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Allelic Composition: Rag1tm1Jsek/Rag1tm1Jsek,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac

 MP:0001204 skin irradiation resistance "decreased incidence of aberrant or damaged cells due to irradiation induced genotoxic damage" [J:65162]
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Allelic Composition: KitlSl-5R/KitlSl-5R
Genetic Background: C3H-KitlSl-5R

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0001212 skin lesions "focal patches of inflammation on the skin" [J:30162]
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Allelic Composition: Tg(MMTV-KLF4)1Rup/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6NTac * FVB/NJ * SJL

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre/ERT)20Efu/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * CD-1

Allelic Composition: Trp53tm1Yjc/Trp53tm1Yjc
Genetic Background: B6.129S1-Trp53tm1Yjc

 MP:0001219 thickened epidermis "increase in the width of the epidermal cell layer in the skin" [J:65146]
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Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR

 MP:0001231 abnormal basal cell layer morphology "structural anomaly of the deepest layer of the epidermis, which is composed of dividing stem cells and anchoring cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR

 MP:0001243 abnormal dermal layer morphology "malformed or atypical condition of the dermal layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:56777]
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Allelic Composition: Tg(MMTV-KLF4)1Rup/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6NTac * FVB/NJ * SJL

 MP:0001244 thin dermal layer "reduced thickness of the dermis" [J:65030]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Lig4tm1Icrf/Lig4tm1Icrf,Trp53tm1Tyj/Trp53+
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas) or (involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ)

Allelic Composition: Trp53tm1Tyj/Trp53+,Xrcc2tm1Pmc/Xrcc2tm1Pmc
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Atrtm1Ofc/Atrtm1Ofc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

Allelic Composition: Sirt6tm2.2Cxd/Sirt6tm2.2Cxd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * FVB/N * NIH Black Swiss

Allelic Composition: Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Ren-cre)#Kwg/0
Genetic Background: involves: 129 * 129P2/OlaHsd

Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0001263 weight loss "progressive reduction of body weight below normal average for age" [J:45400]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Rb1tm1.1Jyjw/Rb1tm1.1Jyjw,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Col1a1tm4(CAG-FGFR2_iIIIb*K660N)Kkw/Col1a1+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Trp53tm1Xu/Trp53tm1Xu,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Dp(4D4Mit190-D4Mit51)1Aam/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0001270 distended abdomen "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Stk11tm1.1Mlfr/Stk11+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0001272 increased metastatic potential 
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Allelic Composition: Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S7-Trp53tm3.1Glo

Allelic Composition: Trp53tm2.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm3.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Bhlha15tm2(Kras)Skz/Bhlha15+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6

Allelic Composition: Cdh1tm1Jjon/Cdh1tm1Jjon,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Cdh1tm1Jjon/Cdh1tm1Jjon,Trp53tm1Brn/Trp53+,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm3Glo/Trp53+,Tg(KRT5-cre/PGR)1Der/?
Genetic Background: involves: 129/Sv * C57BL/6 * FVB * ICR

Allelic Composition: Mtbptm1Glo/Mtbp+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Cdkn2atm1.1Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Trp53tm6Xu/Trp53tm6Xu,Tg(Lck-cre)1Cwi/0
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Rpl27aSfa/Rpl27a+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

Allelic Composition: Espl1Gt(XL058)Byg/Espl1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Dcctm1Nki/Dcctm1Nki,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2a+,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Smad4tm1Rdp/Smad4tm1Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129 * C57BL/6 * DBA/2

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Terttm3Rdp/Terttm3Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

Allelic Composition: Calcatm1.1(cre/ERT2)Ptch/Calca+,Trp53tm1Brn/Trp53tm1Brn,Rb1tm2Brn/Rb1tm2Brn,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S4/SvJae * BALB/c * FVB/N

Allelic Composition: Krastm1Bbd/Kras+,Trp53tm1Brd/Trp53+,Tg(Cela1-tTA)#Eps/?,Tg(tetO-cre)3Jig/?
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * FVB/N

Allelic Composition: Rb1tm3Tyj/Rb1+,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Rb1tm3Tyj/Rb1+,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1

Allelic Composition: Braftm1.1Brd/Braf+,Tg(Vil1-cre)997Gum/0,Trp53tm2Tyj/Trp53tm2Tyj
Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * SJL

Allelic Composition: Brca1tm2Cxd/Brca1tm2Cxd,Pkmtm1.1Mgvh/Pkmtm1.1Mgvh,Tg(MMTV-cre)4Mam/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * 129S7/SvEvBrd * FVB/N

Allelic Composition: Rasal2Gt(463C12)Cmhd/Rasal2Gt(463C12)Cmhd,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S * 129X1/SvJ * C57BL/6 * C57BL/6NCrl

Allelic Composition: Rasal2Gt(463C12)Cmhd/Rasal2+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S * 129X1/SvJ * C57BL/6 * C57BL/6NCrl

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Tg(Krt18-EGFP,-TAg121)36Ysng/0,Trp53tm1Brn/Trp53tm2Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N

Allelic Composition: Cdh1tm2Kem/Cdh1+,Smad4tm2.1Cxd/Smad4tm2.1Cxd,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

Allelic Composition: Cdh1tm2Kem/Cdh1+,Smad4tm2.1Cxd/Smad4tm2.1Cxd,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)7Mul/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

Allelic Composition: Smad4tm2.1Cxd/Smad4tm2.1Cxd,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)7Mul/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Ren-cre)#Kwg/0
Genetic Background: involves: 129 * 129P2/OlaHsd

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Dicer1tm1Tara/Dicer1tm1Tara,Ptentm1Hwu/Ptentm1Hwu,Trp53tm2Tyj/Trp53+,Amhr2tm3(cre)Bhr/Amhr2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd

Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Trp53tm2Tyj/Trp53+,Amhr2tm3(cre)Bhr/Amhr2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd

Allelic Composition: Gt(ROSA)26Sortm1(CAG-Mir182)Dgk/Gt(ROSA)26Sortm1(CAG-Mir182)Dgk,Krastm4Tyj/Krastm4Tyj,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Allelic Composition: Ptch1tm1Yy/Ptch1+,Trp53tm1Brd/Trp53+,Tg(BGLAP-cre)1Clem/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/NJ

Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Trp53tm1Brn/Trp53tm1Brn,Tg(TPO-cre)1Shk/0
Genetic Background: 129.Cg-Trp53tm1Brn Ptentm2.1Ppp Tg(TPO-cre)1Shk

Allelic Composition: Braftm1Mmcm/Braf+,Tg(TPO-cre/ERT2)1139Tyj/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * C57BL/6NTac

Allelic Composition: Apctm2Rak/Apc+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

 MP:0001273 decreased metastatic potential 
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Allelic Composition: Tcrbetm1Che/Tcrbetm1Che,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Cd44tm1Mak/Cd44tm1Mak,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * C57BL/6J

Allelic Composition: Krastm4Tyj/Krastm4Tyj,Mir182tm1.1Dgk/Mir182tm1.1Dgk,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Allelic Composition: Krastm4Tyj/Krastm4Tyj,Mir182tm1.1Dgk/Mir182+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Allelic Composition: Cpt1cGt(XL823)Byg/Cpt1c+,Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Rab11fip1tm1.1Jicn/Rab11fip1tm1.1Jicn,Tg(Pdx1-cre)6Tuv/0,Trp53tm2.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae * FVB/N

Allelic Composition: Epha2tm1Jrui/Epha2tm1Jrui,Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Trp53tm2.1Tyj/Trp53+
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * FVB/N

 MP:0001296 macrophthalmia "increased average size of the eyes" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Tg(Cryaa-NCOA6*)AD5Cve/0
Genetic Background: involves: 129S7/SvEvBrd * FVB/N

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
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Allelic Composition: Nos2tm1Mrl/Nos2tm1Mrl,Tg(Myh6-Tnf)1.6Amf/?
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB

 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
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Allelic Composition: Atf4tm1Jml/Atf4tm1Jml
Genetic Background: involves: 129X1/SvJ

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Tg(Cryaa-NCOA6*)AD5Cve/0
Genetic Background: involves: 129S7/SvEvBrd * FVB/N

 MP:0001304 cataracts "complete or partial opacity of the lens" [J:65031]
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Nf1tm1Par/Nf1tm1Par,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Rb1tm1Tyj/Rb1tm2Brn,Rbl1tm1Tyj/Rbl1+,Trp53tm1Brn/Trp53tm1Brn,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Atp/0
Genetic Background: involves: 129S2/SvPas * FVB/N

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129S2-Trp53tm1Tyj/J

 MP:0001327 reduced retinal photoreceptor cell number "fewer than the expected number of rods and/or cones" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Atp/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0001330 abnormal optic nerve morphology "malformation, misprojection or atrophy in the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p/Oca2p-80K
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0001333 absent optic nerve "absence of the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

 MP:0001392 abnormal locomotor activity "altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
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Allelic Composition: Dp(4D4Mit190-D4Mit51)1Aam/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brd/Trp53tm1Brd,Tg(Gfap-cre)2Brn/0
Genetic Background: involves: 129 * 129S7/SvEvBrd * FVB/N

Allelic Composition: Ptentm1Rdp/Pten+,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S4/SvJae * FVB/N

Allelic Composition: Trp53tm1Elee/Trp53tm1Tyj,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * FVB/N

Allelic Composition: Grid2Lc-J/Grid2+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * BALB/cByJ * C57BL/6

Allelic Composition: Nf1tm1Par/Nf1+,Ptentm1Hwu/Pten+,Trp53tm1Tyj/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Trp53tm1Elee/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Ptentm1Hwu/Pten+,Trp53tm1Elee/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (C3H/HeJ x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (CAST/EiJ x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (SJL/J x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0001394 circling "repeated, compulsive movement in a circle; often associated with inner ear defects" [MGI:CLS, J:61295]
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Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brd/Trp53tm1Brd,Tg(Gfap-cre)2Brn/0
Genetic Background: involves: 129 * 129S7/SvEvBrd * FVB/N

Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0001396 unidirectional circling "circling behavior in one direction only, either clockwise or counterclockwise" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Nf1tm1Par/Nf1+,Ptentm1Hwu/Pten+,Trp53tm1Tyj/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Trp53tm1Elee/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Ptentm1Hwu/Pten+,Trp53tm1Elee/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brd/Trp53tm1Brd,Tg(Gfap-cre)2Brn/0
Genetic Background: involves: 129 * 129S7/SvEvBrd * FVB/N

Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0001412 excessive scratching "compulsive scraping of the skin, usually with the nails" [J:61340]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL

Allelic Composition: Smarcb1tm2Sho/Smarcb1+,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0001429 dehydration "excessive water loss from the body or from an organ or bodily part" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50053]
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Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd,Xrcc5tm1Dbr/Xrcc5tm1Dbr
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL

 MP:0001488 increased startle reflex "reduced threshold or more severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Nf1tm1Par/Nf1+,Ptentm1Hwu/Pten+,Trp53tm1Tyj/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Trp53tm1Elee/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Ptentm1Hwu/Pten+,Trp53tm1Elee/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

 MP:0001505 hunched posture "stooped low with the limbs pulled in close to the body and arched back" [J:67231, J:30404]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Rb1tm1Tyj/Rb1tm1Tyj,Tg(Rb1)1Blg/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

 MP:0001525 impaired balance "reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123]
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Allelic Composition: Nbntm2Zqw/Nbntm2Zqw,Tg(Nes-cre)1Wme/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brd/Trp53tm1Brd,Tg(Gfap-cre)2Brn/0
Genetic Background: involves: 129 * 129S7/SvEvBrd * FVB/N

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd,Xrcc5tm1Dbr/Xrcc5tm1Dbr
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S4/SvJae * FVB/N

Allelic Composition: Trp53tm1Elee/Trp53tm1Tyj,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * FVB/N

 MP:0001544 abnormal cardiovascular system physiology "anomalous function of the blood, blood vessels, and/or the heart" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas

 MP:0001545 abnormal hematopoietic system physiology "anomalous function of the fluid and/or its suspended elements that circulate(s) through the heart, arteries, capillaries, and veins" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Trp53tm1Tyj/Trp53tm3.1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

 MP:0001552 increased circulating triglyceride level "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]
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Allelic Composition: Apctm2Rak/Apc+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

 MP:0001559 hyperglycemia "abnormally high concentration of glucose in the blood; generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Huwe1tm1Wgu/Y,Tg(Ins2-cre)23Herr/0,Trp53tm1Thl/Trp53tm1Thl
Genetic Background: involves: C57BL/6J * CBA/J

Allelic Composition: Gt(ROSA)26Sortm1(Gck)Ydor/Gt(ROSA)26Sor+,Trp53tm1Brn/Trp53tm1Brn,Tg(Ins2-cre)25Mgn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA

 MP:0001577 anemia "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
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Allelic Composition: Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm2Glo/Trp53tm2Glo
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0001625 cardiac hypertrophy "an increase in size of the cardiac tissue, not due to increased cell number " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Trp53tm1.1Tldo/Trp53+
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

 MP:0001648 abnormal apoptosis "excessive or absent cell death in a particular tissue or cell type" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:25248]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm2Glo/Trp53tm2Glo
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Tg(ACTB-NOTCH1)1Shn/0,Tg(Nes-cre)1Kln/0,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Npm1Gt(VICTR37)704Lex/Npm1Gt(VICTR37)704Lex,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Xu/Trp53tm1Xu,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Cenpjtm1d(EUCOMM)Wtsi/Cenpjtm1d(EUCOMM)Wtsi,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N * FVB/NJ

 MP:0001658 increased mortality induced by gamma-irradiation "greater sensitivity to doses of ionizing radiation" [J:51834]
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Allelic Composition: Gt(ROSA)26Sortm1(Pim1-E2F1)Rebr/Gt(ROSA)26Sor+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129P2/OlaHsd * FVB * FVB/N

 MP:0001661 extended life span "persistence of life for a longer period than is the norm for an organism" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Trp53tm1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm3.1Glo/Trp53tm4Glo,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Mdm4tm2Glo/Mdm4tm2.1Glo,Tg(Myh6-cre)2182Mds/0,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J * FVB/N

Allelic Composition: Mdm4tm2Glo/Mdm4tm2.1Glo,Tg(Myh6-cre)2182Mds/0,Trp53tm1Tyj/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Wasf1tm2Jsco/Wasf1tm2Jsco
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Mdm4tm1Glo/Mdm4tm1Glo,Trp53tm1Adv/Trp53tm1Adv
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Mdm4tm1Glo/Mdm4tm1Glo,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Pknox1tm1Fbla/Pknox1tm1Fbla,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Mdm4Gt(VICTR20)7Lex/Mdm4+,Trp53tm1.1Xlu/Trp53tm1.1Xlu
Genetic Background: involves: 129S5/SvEvBrd * 129S6/SvEvTac * C57BL/6 * FVB/N

 MP:0001688 abnormal somite development "anomalous formation of any of the paired, metamerically arranged cell masses formed in the embryonic paraxial mesoderm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ets1tm1.1Dds/Ets1+
Genetic Background: 129S6/SvEvTac-Ets1tm1.1Dds

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
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Allelic Composition: Tsg101tm1Mak/Tsg101tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * CD-1)

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc1tm1Rpe/Xrcc1tm1Rpe
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ

Allelic Composition: Cdc7tm1Hmas/Cdc7tm1Hmas,Trp53tm2Mok/Trp53tm2Mok
Genetic Background: involves: 129S/Sv * C57BL/6

Allelic Composition: Bard1tm1Thl/Bard1tm1Thl,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S1/Sv * 129S2/SvPas

Allelic Composition: Brca1tm1Cxd/Brca1tm1Cxd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Metap2tm1.2Ccr/Metap2tm1.2Ccr,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * FVB/N

Allelic Composition: Mdm4Gt(VICTR20)7Lex/Mdm4Gt(VICTR20)7Lex,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd

Allelic Composition: Kat2atm1Roth/Kat2atm1Roth,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Brca1tm1Mak/Brca1tm1Mak,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

Allelic Composition: Cops6Gt(RRI087)Byg/Cops6Gt(RRI087)Byg,Trp53tm1Glo/Trp53tm1Glo
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Rnaseh2btm1a(EUCOMM)Wtsi/Rnaseh2btm1a(EUCOMM)Wtsi,Trp53tm1Mlh/Trp53tm1Mlh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N

 MP:0001700 abnormal embryo turning "atypical axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (Mus:E8.5-E9.5) such that the curvature of the entire trunk region is reversed and the neural ectoderm moves to the convex region and the midgut region becomes located in the concave region" [The Atlas of Mouse Development:ISBN 0-12-402035-6, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ets1tm1.1Dds/Ets1+
Genetic Background: 129S6/SvEvTac-Ets1tm1.1Dds

 MP:0001704 abnormal dorsal-ventral axis patterning "anomaly in the development or formation of the axis that runs from the front to the back surface of the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cenpjtm1d(EUCOMM)Wtsi/Cenpjtm1d(EUCOMM)Wtsi,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N * FVB/NJ

 MP:0001718 abnormal yolk sac "malformed extraembryonic tissue which contributes to hematopoietic circulation" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:12623]
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Allelic Composition: Brca1tm1Mak/Brca1tm1Mak,Cdkn1atm1Tyj/Cdkn1atm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0001724 abnormal extraembryonic endoderm formation "malformation of the endoderm of the extraembryonic tissue that appears prior to gastrulation and performs critical functions during embryogenesis including nutrient uptake and transport from the mother to the embryo" [J:62628]
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Allelic Composition: Pknox1tm1Fbla/Pknox1tm1Fbla,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001726 abnormal allantois "malformed fetal membrane which contributes to the formation of the umbilical cord and placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:12622]
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Allelic Composition: Brca1tm1Mak/Brca1tm1Mak,Cdkn1atm1Tyj/Cdkn1atm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

Allelic Composition: Gnl3Gt(W223E05)Wrst/Gnl3Gt(W223E05)Wrst,Trp53tm1Tyj/Trp53tm5Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

Allelic Composition: Emg1tm1Hdin/Emg1tm1Hdin,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S * 129S2/SvPas * 129X1/SvJ * CD-1 * ICR

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0001792 impaired wound healing "reduced ability or inability to self-repair and close wounds" [J:65302, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0001806 decreased IgM "less than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cd79atm1(cre)Reth/Cd79a+,Huwe1tm1.1Mak/Y,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL

 MP:0001823 thymus hypoplasia "small size due to reduced cell number in the thymus" [J:23255]
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Allelic Composition: Ssbp2tm1Lana/Ssbp2tm1Lana,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * BALB/c * C57BL/6

 MP:0001829 increased activated T cell number "greater than normal numbers of effector T cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Brca2tm1Mak/Brca2tm2Mak,Trp53tm1Brd/Trp53tm1Brd,Tg(Lck-cre)548Jxm/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0001846 increased inflammatory response "greater than expected response to injury, infection, or insult " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

 MP:0001860 liver inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the liver" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

 MP:0001861 lung inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the lung" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

 MP:0001864 vasculitis "inflammation of a blood or lymph vessel" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

 MP:0001879 abnormal lymphatic vessel morphology "malformation of the network of vessels which carries lymph around the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Myo5argsc450/Myo5argsc450
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

 MP:0001883 mammary adenocarcinoma "higher than normal incidence of malignant tumors of the mammary gland" [J:62919]
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(MMTV-cre)AElee/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(MMTV-cre)BElee/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(Wap-rtTA-cre)10Whl/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Cdh1tm1Jjon/Cdh1tm1Jjon,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Cdh1tm1Jjon/Cdh1tm1Jjon,Trp53tm1Brn/Trp53+,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Cdh1tm1Jjon/Cdh1+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Trp53tm3.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae * SKH1

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Brca2tm1Brn/Brca2+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Brn/Trp53+,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Brca1tm2Mak/Brca1tm2Mak,Trp53tm1Brd/Trp53+,Tg(Wap-cre)11738Mam/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA * SJL

Allelic Composition: Tg(MMTV-AURKA)#Cxd/?,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * FVB/N

Allelic Composition: Chek1tm2.1Sje/Chek1+,Trp53tm1Brn/Trp53+,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+,Tg(MMTV-cre)#Tfln/0,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

Allelic Composition: Trp53tm1Brn/Trp53+,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Dcctm1Nki/Dcctm1Nki,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Cdh1tm2Kem/Cdh1+,Smad4tm2.1Cxd/Smad4tm2.1Cxd,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)7Mul/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

Allelic Composition: Smad4tm2.1Cxd/Smad4tm2.1Cxd,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)7Mul/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0001884 mammary alveolar hyperplasia 
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Allelic Composition: Brca1tm2Cxd/Brca1tm2Cxd,Tg(MMTV-cre)4Mam/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB

Allelic Composition: Brca1tm2Cxd/Brca1tm2Cxd,Tg(MMTV-cre)4Mam/0,Tg(MMTV-rtTA)1Lach/0,Tg(tetO-Esr1)#Paf/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB

 MP:0001885 mammary ductal hyperplasia 
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Allelic Composition: Tg(MMTV-AURKA)#Cxd/?,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0001891 hydroencephaly "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2a+,Tg(NES-TVA)J12Ech/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N * SJL

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Trp53bhy/Trp53bhy
Genetic Background: C57BL/6JSfdAnu-Trp53bhy/Anu

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Ing2tm1.1Ccha/Ing2tm1.1Ccha,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0001940 testicular hypoplasia "decreased cell number in the testicles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001953 respiratory failure "cessation of or failure to commence breathing" [MGI:cls, J:60159]
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Allelic Composition: Braftm1Mmcm/Braf+,Tg(TPO-cre/ERT2)1139Tyj/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * C57BL/6NTac

 MP:0001954 respiratory distress "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
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Allelic Composition: Dcntm1Ioz/Dcntm1Ioz,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

Allelic Composition: Dcntm1Ioz/Dcn+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd,Xrcc5tm1Dbr/Xrcc5tm1Dbr
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Col1a1tm4(CAG-FGFR2_iIIIb*K660N)Kkw/Col1a1+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6

 MP:0002009 preneoplasia "state preceding the pathological process resulting in a neoplasm; does not necessarily imply cancerous development" [J:47225]
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Allelic Composition: Brca1tm2Cxd/Brca1tm2Cxd,Tg(MMTV-cre)4Mam/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB

Allelic Composition: Brca1tm2Cxd/Brca1tm2Cxd,Tg(MMTV-cre)4Mam/0,Tg(MMTV-rtTA)1Lach/0,Tg(tetO-Esr1)#Paf/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB

 MP:0002013 pilomatriculoma "hair follicle tumor" [J:51296]
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Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Cdh1tm1Jjon/Cdh1+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0002014 papilloma "benign epithelial tumor" [J:47225]
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Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Gfap-cre)2Brn/0
Genetic Background: involves: 129 * 129P2/OlaHsd * FVB/N

 MP:0002016 ovarian cysts "cystic ovary; usually refers to a benign growth" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
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Allelic Composition: Braftm1Mmcm/Braftm1Mmcm,Nkx3-1tm4(cre/ERT2)Mms/Nkx3-1+,Ptentm1Hwu/Pten+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: KitW-v/KitW-v,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N

 MP:0002018 malignant tumors "higher than normal incidence of locally invasive, destructive and metastatic tumors " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:44427]
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Allelic Composition: Brca2tm1Mak/Brca2tm2Mak,Trp53tm1Brd/Trp53tm1Brd,Tg(Lck-cre)548Jxm/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Brca2tm1Cam/Brca2tm1Brn,Tg(Pdx1-cre)6Tuv/0,Trp53tm3Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Brd/Trp53+
Genetic Background: B6.129-Trp53tm1Brd Nf1tm1Fcr

 MP:0002019 abnormal tumor incidence "deviation from the expected number of abnormal growths of a specific tissue in a specific population" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

Allelic Composition: Trp53tm2Xu/Trp53tm2Xu,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

Allelic Composition: Trp53tm4Xu/Trp53tm4Xu
Genetic Background: Not Specified

Allelic Composition: Cdkn2atm1Cjs/Cdkn2atm1Cjs,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * NIH/OlaHsd

Allelic Composition: Rpl27aSfa/Rpl27a+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6

 MP:0002020 increased tumor incidence "greater than average number of tumors, usually a specific type" [MGI:cls, J:34193]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Wrntm1Led/Wrntm1Led
Genetic Background: either: (involves: 129S/SvEv) or (involves: 129S/SvEv * NIH Black Swiss)

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brd/Trp53+,Tg(Rbp3-cre)1Brn/0
Genetic Background: involves: 129 * 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: H2afxtm1Fwa/H2afxtm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm2Glo/Trp53tm2Glo
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Cdkn1btm1Mlf/Cdkn1btm1Mlf,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: C57BL/6J * C3H * NIH

Allelic Composition: Cdkn1btm1Mlf/Cdkn1btm1Mlf,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Prdm2tm1Shg/Prdm2tm1Shg,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(MMTV-cre)BElee/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(Wap-rtTA-cre)10Whl/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Psmb9tm1Stl/Psmb9tm1Stl,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Dcntm1Ioz/Dcntm1Ioz,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

Allelic Composition: Dcntm1Ioz/Dcn+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

Allelic Composition: Nbntm2Zqw/Nbntm2Zqw,Trp53tm1Brd/Trp53tm1Brd,Tg(Nes-cre)1Wme/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Rb1tm1Tyj/Rb1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

Allelic Composition: Trp53tm3.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Tyj/Trp53tm3.1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

Allelic Composition: Trp53Bbl/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53Bbl/Anu

Allelic Composition: Trp53bhy/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53bhy/Anu

Allelic Composition: Trp53tm1Wahl/Trp53tm1Wahl
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

Allelic Composition: Trp53tm2Xu/Trp53tm2Xu
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Tg(Nes-cre)1Kln/0,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * SJL

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc2tm1Pmc/Xrcc2tm1Pmc
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Suds3tm1.1Rdp/Suds3+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB

Allelic Composition: Ryr2tm1(CAG-KRAS*G12V,-lacZ)Nobs/Ryr2tm1(CAG-KRAS*G12V,-lacZ)Nobs,Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Ryr2tm1(CAG-KRAS*G12V,-lacZ)Nobs/Ryr2tm1(CAG-KRAS*G12V,-lacZ)Nobs,Trp53tm1Sia/Trp53+
Genetic Background: involves: 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Ppm1dtm1Lad/Ppm1dtm1Lad,Tg(IghMyc)22Bri/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129 * C57BL * FVB/N * SJL

Allelic Composition: Trp53tm2Brd/Trp53tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm4Xu/Trp53tm4Xu
Genetic Background: Not Specified

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Mtbptm1Glo/Mtbp+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Glipr1tm1Tt/Glipr1+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Glipr1tm1Tt/Glipr1tm1Tt,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Sirt1tm1.1Cxd/Sirt1+,Trp53tm1Brd/Trp53+
Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB/N)

Allelic Composition: Kat5tm1Jwl/Kat5+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

Allelic Composition: Trp53tm1Glo/Trp53tm1Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53tm1Ldo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1.1Brn/Trp53tm1.1Brn
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Brca2tm1Brn/Brca2+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Brn/Trp53+,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Brca2tm1Mak/Brca2tm2Mak,Trp53tm1Brd/Trp53tm1Brd,Tg(Lck-cre)548Jxm/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Brca1tm2Mak/Brca1tm2Mak,Trp53tm1Brd/Trp53tm1Brd,Tg(Wap-cre)11738Mam/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA * SJL

Allelic Composition: Trp53tm1Brd/Trp53+,Trp53bp2tm1Cdlo/Trp53bp2+
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Cdkn2atm1.1Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Stk11tm1Mmt/Stk11+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

Allelic Composition: Trp53tm2Mok/Trp53tm2Mok
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: Trp53tm7.1Xu/Trp53tm7.1Xu
Genetic Background: Not Specified

Allelic Composition: Trp53tm1Holl/Trp53tm7.1Xu
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Irf1tm1Mak/Irf1tm1Mak,Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Dcctm1Nki/Dcctm1Nki,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Rnf168Gt(405F11)Cmhd/Rnf168Gt(405F11)Cmhd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Rnf168Gt(156B6)Cmhd/Rnf168Gt(156B6)Cmhd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Trp53tm1Thst/Trp53tm1Thst
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Trp53tm1Thst/Trp53+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Trp53tm1.1Thst/Trp53tm1.1Thst
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Trp53tm1.1Thst/Trp53+
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Trp53tm1Thst/Trp53tm1.1Thst
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Exo1tm2Wed/Exo1tm2Wed,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Pax7tm2.1(cre/ERT2)Fan/Pax7+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * 129X1/SvJ * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Myod1tm1.1(cre/ERT,TVA)Gcg/Myod1+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Allelic Composition: Clp1tm1.1Pngr/Clp1tm1.1Pngr,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * C57BL/6J

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Nf1tm1Tyj/Nf1+,Suz12Gt(Betageo)1Khe/Suz12+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Mdm4tm2Glo/Mdm4tm2.1Glo,Tg(Myh6-cre)2182Mds/0,Trp53tm1Tyj/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0002021 increased incidence of induced tumors "higher than normal frequency of tumor incidence induced by a carcinogen or mutagen" [J:44427]
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Allelic Composition: H2afxtm1Nus/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002023 B cell derived lymphoma "heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

Allelic Composition: H2afxtm1Fwa/H2afxtm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

Allelic Composition: H2afxtm1Fwa/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm4Tyj/Trp53tm4Tyj
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm3.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53Bbl/Trp53Bbl
Genetic Background: C57BL/6JSfdAnu-Trp53Bbl/Anu

Allelic Composition: Lig4tm1Icrf/Lig4tm1Icrf,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas) or (involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ)

Allelic Composition: Nhej1tm1Fwa/Nhej1tm1Fwa,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129/Sv

Allelic Composition: Tg(IghMyc)22Bri/0,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129/Sv * 129X1/SvJ * C57BL * C57BL/6 * SJL

Allelic Composition: Kat5tm1Jwl/Kat5+,Tg(IghMyc)22Bri/0,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129 * C57BL * C57BL/6 * SJL

Allelic Composition: Trp53tm1.1Awbr/Trp53tm1.1Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Rag2tm1.1Desi/Rag2tm1.1Desi,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(Ly6e-MALT1)#Isg/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

Allelic Composition: Rnf168Gt(405F11)Cmhd/Rnf168Gt(405F11)Cmhd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Rnf168Gt(156B6)Cmhd/Rnf168Gt(156B6)Cmhd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Rps27lGt(IST11658B7)Tigm/Rps27lGt(IST11658B7)Tigm,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6N

Allelic Composition: Trp53tm1Tyj/Trp53tm1.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm1.1Umol/Trp53tm1.1Umol
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm2.1Umol/Trp53tm2.1Umol
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

 MP:0002024 T cell derived lymphoma "group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Rad50tm2Jpt/Rad50tm2Jpt,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6J

Allelic Composition: Rag2tm1Fwa/Rag2+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6J

Allelic Composition: H2afxtm1Fwa/H2afxtm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

Allelic Composition: H2afxtm1Fwa/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Cdkn1btm1Mlf/Cdkn1btm1Mlf,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: C57BL/6J * C3H * NIH

Allelic Composition: Cdkn1btm1Mlf/Cdkn1btm1Mlf,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Dcntm1Ioz/Dcntm1Ioz,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

Allelic Composition: Dcntm1Ioz/Dcn+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

Allelic Composition: Trp53tm1Gev/Trp53tm1Gev
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

Allelic Composition: Trp53tm1Tyj/Trp53tm3.1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

Allelic Composition: Trp53Bbl/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53Bbl/Anu

Allelic Composition: Trp53bhy/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53bhy/Anu

Allelic Composition: Tcrbetm1Che/Tcrbetm1Che,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Tcrbetm1Che/Tcrbetm1Che,Tcrdtm1Mom/Tcrdtm1Mom,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Tg(Nes-cre)1Kln/0,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * SJL

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc2tm1Pmc/Xrcc2tm1Pmc
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+,Xrcc2tm1Pmc/Xrcc2tm1Pmc
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm4Xu/Trp53tm4Xu
Genetic Background: Not Specified

Allelic Composition: Fbxw7tm1Kei/Fbxw7tm1Kei,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Lck-cre)1Cwi/?
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Nhej1tm1Fwa/Nhej1tm1Fwa,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129/Sv

Allelic Composition: Trp53tm1Glo/Trp53tm1Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Brd/Trp53tm1Ldo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd,Xrcc5tm1Dbr/Xrcc5tm1Dbr
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Ccnd3tm1Pisc/Ccnd3tm1Pisc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Brca1tm2Mak/Brca1tm2Mak,Tg(Lck-cre)548Jxm/?,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

Allelic Composition: Rag1tm1Jsek/Rag1tm1Jsek,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm6Xu/Trp53tm6Xu,Tg(Lck-cre)1Cwi/0
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Tg(Lck-cre)1Cwi/0
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Rev3ltm1Rwd/Rev3ltm2.1Rwd,Trp53tm1Brd/Trp53tm1Brd,Tg(MMTV-cre)1Mam/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Ssbp2tm1Lana/Ssbp2tm1Lana,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Trp53tm1.1Awbr/Trp53tm1.1Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Rag2tm1.1Desi/Rag2tm1.1Desi,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

Allelic Composition: Rag2tm2.1Desi/Rag2tm2.1Desi,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Dclre1atm1Rleg/Dclre1atm1Rleg,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

Allelic Composition: Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+,Tg(MMTV-cre)#Tfln/0,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

Allelic Composition: Trp53tm1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm4Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Rag2tm1.1Mss/Rag2tm1.1Mss,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+,Tacc3tm1.1Tno/Tacc3tm1.2Tno,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+,Tacc3tm1.1Tno/Tacc3+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Thst/Trp53tm1Thst
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Trp53tm1.1Thst/Trp53tm1.1Thst
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Rps27lGt(IST11658B7)Tigm/Rps27lGt(IST11658B7)Tigm,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6N

Allelic Composition: Trp53tm1Tyj/Trp53tm1.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm1.1Umol/Trp53tm1.1Umol
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm2.1Umol/Trp53tm2.1Umol
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Ino80tm1.1Schg/Ino80+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0002026 leukemia "progressive proliferation of abnormal leukocytes in hematopoietic tissues, organs and blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18542]
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53Bbl/Trp53Bbl
Genetic Background: C57BL/6JSfdAnu-Trp53Bbl/Anu

Allelic Composition: Trp53bhy/Trp53bhy
Genetic Background: C57BL/6JSfdAnu-Trp53bhy/Anu

Allelic Composition: Mtbptm1Glo/Mtbp+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Ightm2.1(Tag)Rwhe/Igh+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Ightm1.1(Tag)Rwhe/Igh+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

 MP:0002027 lung adenocarcinoma "malignant neoplasm of epithelial cells in the lung" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:18542]
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm3.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Braftm1Mmcm/Braf+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Trp53tm1Brn/Trp53tm1.1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Krastm4Tyj/Kras+,Map2k7tm1.1Twad/Map2k7tm1.2Twad,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Krastm5Tyj/Kras+,Trp53tm1.1Dgk/Trp53tm1.1Dgk
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Lejo/Trp53tm1Lejo
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Krastm4Tyj/Kras+,Sftpctm1.1(cre/ERT2)Ptch/Sftpc+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Col1a1tm4(CAG-FGFR2_iIIIb*K660N)Kkw/Col1a1+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6

Allelic Composition: Rb1tm2Brn/Rb1+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-Kras2)12Hev/0,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

 MP:0002030 neurofibrosarcoma "malignant neoplasm of fibrous tissue of the nervous system" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18542]
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Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Nf1tm1Tyj/?,Nstr1C57BL/6J/Nstr1C57BL/6J,Trp53tm1Tyj/?
Genetic Background: involves: 129S2/SvPas * A/J * C57BL/6J

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Nf1tm1Tyj/Nf1+,Suz12Gt(Betageo)1Khe/Suz12+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0002032 sarcoma "connective tissue neoplasm associated with the proliferation of mesodermal cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: H2afxtm1Fwa/H2afxtm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

Allelic Composition: H2afxtm1Fwa/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm2Glo/Trp53tm2Glo
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Cdkn1btm1Mlf/Cdkn1btm1Mlf,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: C57BL/6J * C3H * NIH

Allelic Composition: Cdkn1btm1Mlf/Cdkn1btm1Mlf,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Trp53tm4Tyj/Trp53tm4Tyj
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Psmb9tm1Stl/Psmb9tm1Stl,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S7-Trp53tm3.1Glo

Allelic Composition: Nbntm2Zqw/Nbntm2Zqw,Trp53tm1Brd/Trp53tm1Brd,Tg(Nes-cre)1Wme/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Rb1tm1Tyj/Rb1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Stk11tm1.1Mlfr/Stk11+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc2tm1Pmc/Xrcc2tm1Pmc
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Tg(MMTV-KLF4)1Rup/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6NTac * FVB/NJ * SJL

Allelic Composition: Trp53tm3.1Glo/Trp53tm3.1Glo
Genetic Background: B6.129S7-Trp53tm3.1Glo

Allelic Composition: Trp53tm4Xu/Trp53tm4Xu
Genetic Background: Not Specified

Allelic Composition: Sirt1tm1.1Cxd/Sirt1+,Trp53tm1Brd/Trp53+
Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB/N)

Allelic Composition: Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Brd/Trp53tm1Ldo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd,Xrcc5tm1Dbr/Xrcc5tm1Dbr
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S4/SvJae * FVB/N

Allelic Composition: Trp53tm1Elee/Trp53tm1Tyj,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Trp53tm7.1Xu/Trp53tm7.1Xu
Genetic Background: Not Specified

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Mdm2tm4.1Glo/Mdm2tm4.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm4.1Glo Trp53tm3.1Glo

Allelic Composition: Brca2tm1Cam/Brca2tm1Brn,Tg(Pdx1-cre)6Tuv/0,Trp53tm3Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Dclre1atm1Rleg/Dclre1a+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm4Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm3.1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Krastm5Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sortm1(cre/ERT2)Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Krastm5Tyj/Kras+,Trp53tm1.1Dgk/Trp53tm1.1Dgk
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(Prrx1-FUS/DDIT3)1Mete/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

Allelic Composition: Trp53tm1Yjc/Trp53tm1Yjc
Genetic Background: B6.129S1-Trp53tm1Yjc

Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Brd/Trp53+
Genetic Background: B6.129-Trp53tm1Brd Nf1tm1Fcr

Allelic Composition: Rnf168Gt(405F11)Cmhd/Rnf168Gt(405F11)Cmhd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Rnf168Gt(156B6)Cmhd/Rnf168Gt(156B6)Cmhd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Exo1tm3.1Wed/Exo1tm3.1Wed,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Pax7tm2.1(cre/ERT2)Fan/Pax7+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * 129X1/SvJ * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Myod1tm1.1(cre/ERT,TVA)Gcg/Myod1+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Allelic Composition: Rtel1tm2.1Hdin/Rtel1tm2.1Hdin,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Ren-cre)#Kwg/0
Genetic Background: involves: 129 * 129P2/OlaHsd

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

Allelic Composition: Trp53tm1Tyj/Trp53tm1.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Ino80tm1.1Schg/Ino80+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0002033 malignant triton tumors " malignant tumor with neurogenic and myogenic differentiation; usually arises in tissues of neural crest origin" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877]
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Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

 MP:0002035 leiomyosarcoma "malignant tumor derived from smooth (nonstriated) muscle" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877]
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Allelic Composition: Rb1tm1Tyj/Rb1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Trp53tm1.1Thst/Trp53tm1.1Thst
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

 MP:0002036 rhabdomyosarcoma "malignant tumor derived from skeletal (striated) muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58877]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Allelic Composition: Ryr2tm1(CAG-KRAS*G12V,-lacZ)Nobs/Ryr2tm1(CAG-KRAS*G12V,-lacZ)Nobs,Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Ryr2tm1(CAG-KRAS*G12V,-lacZ)Nobs/Ryr2tm1(CAG-KRAS*G12V,-lacZ)Nobs,Trp53tm1Sia/Trp53+
Genetic Background: involves: 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Fostm1Wag/Fostm1Wag,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Fostm1Wag/Fostm1Wag,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: SufuGt(XB699)Byg/Sufu+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Ptch1tm1Mps/Ptch1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6

Allelic Composition: Myf6tm1(cre)Mrc/Myf6+,Pax3tm1Mrc/Pax3tm1Mrc,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

Allelic Composition: Myf6tm1(cre)Mrc/Myf6+,Pax3tm1Mrc/Pax3tm1Mrc,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Cdkn2atm1.1Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0002037 fibrohistocytoma "slowly growing skin nodule derived from cellular fibrous tissue; often surrounds capillaries" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877]
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Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

 MP:0002038 carcinoma "malignant neoplasm arising from epithelial cells, usually glandular or squamous" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S7-Trp53tm3.1Glo

Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

Allelic Composition: Trp53tm3.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Tyj/Trp53tm3.1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Trp53tm1Thl/Trp53tm1Thl,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * DBA/2

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm3Glo/Trp53+,Tg(KRT5-cre/PGR)1Der/?
Genetic Background: involves: 129/Sv * C57BL/6 * FVB * ICR

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Tg(KRT5-cre/PGR)1Der/?
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * FVB * ICR

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm3Glo,Tg(KRT5-cre/PGR)1Der/?
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * FVB * ICR

Allelic Composition: Cdkn2atm1Cjs/Cdkn2atm1Cjs,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * NIH/OlaHsd

Allelic Composition: Sirt1tm1.1Cxd/Sirt1+,Trp53tm1Brd/Trp53+
Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB/N)

Allelic Composition: Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tg(KRT14-cre)8Brn/0,Tg(KRT5-Akt1*)Jmpa/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * DBA/2J * FVB/N

Allelic Composition: Ptentm1Mro/Ptentm1Mro,Tg(KRT14-cre)8Brn/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * DBA/2J * FVB/N

Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Rev3ltm1Rwd/Rev3ltm2.1Rwd,Trp53tm1Brd/Trp53+,Tg(MMTV-cre)1Mam/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Mdm2tm4.1Glo/Mdm2tm4.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm4.1Glo Trp53tm3.1Glo

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)105Ayn/0
Genetic Background: FVB.Cg-Trp53tm1Brn Tg(MMTV-cre)105Ayn

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)105Ayn/0
Genetic Background: FVB.Cg-Trp53tm1Brn Rb1tm2Brn Tg(MMTV-cre)105Ayn

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Espl1Gt(XL058)Byg/Espl1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg

Allelic Composition: Espl1Gt(XL058)Byg/Espl1+,Trp53tm1Tyj/Trp53+
Genetic Background: B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Krt19tm1(cre/ERT)Ggu/Krt19+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac

Allelic Composition: Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+,Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Gfap-cre)2Brn/0
Genetic Background: either: (involves: 129 * 129P2/OlaHsd * FVB/N) or (involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB/N)

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Gfap-cre)2Brn/0
Genetic Background: involves: 129 * 129P2/OlaHsd * FVB/N

Allelic Composition: Trp53tm1Thst/Trp53tm1Thst
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Trp53tm1.1Thst/Trp53tm1.1Thst
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Csnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn,Tg(Vil-cre/ERT2)23Syr/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * C57BL/6 * CD-1 * DBA/2

Allelic Composition: Csnk1a1tm1.1Ybn/Csnk1a1+,Tg(Vil-cre/ERT2)23Syr/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * C57BL/6 * CD-1 * DBA/2

Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Tg(Krt18-EGFP,-TAg121)36Ysng/0,Trp53tm1Brn/Trp53tm2Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N

Allelic Composition: Dicer1tm1Tara/Dicer1tm1Tara,Ptentm1Hwu/Ptentm1Hwu,Trp53tm2Tyj/Trp53+,Amhr2tm3(cre)Bhr/Amhr2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Tyj/Trp53tm1.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

 MP:0002039 neuroblastoma "malignant neoplasm characterized by immature nerve cells of embryonic type" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58877]
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Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Allelic Composition: Tg(Th-MYCN)41Waw/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * BALB/c * C57BL/6J * FVB/N

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002041 pituitary adenoma "appearance of benign neoplasms of the pituitary" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042]
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Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL

 MP:0002044 colonic adenoma "benign tumors of the large intestine" [J:38772]
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Allelic Composition: Rb1tm1.1Jyjw/Rb1tm1.1Jyjw,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

Allelic Composition: Rasal2Gt(463C12)Cmhd/Rasal2Gt(463C12)Cmhd,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S * 129X1/SvJ * C57BL/6 * C57BL/6NCrl

 MP:0002048 lung adenoma "benign epithelial neoplasm of the lung" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:57631]
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Allelic Composition: Trp53tm3.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae * SKH1

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Scgb1a1tm1(cre/ERT)Blh/Scgb1a1+,Trp53tm5Tyj/Trp53+
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Sftpctm1(cre/ERT2)Blh/Sftpc+,Trp53tm5Tyj/Trp53+
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Sftpctm1.1(cre/ERT2)Ptch/Sftpc+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB

Allelic Composition: Krastm4Tyj/Kras+,Mapkapk2tm1.1Yaff/Mapkapk2tm1.1Yaff,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Allelic Composition: Krastm1.1Hbji/Krastm1.1Hbji,Trp53tm5Tyj/Trp53tm5Tyj
Genetic Background: involves: 129S4/SvJae

 MP:0002049 extremity angiosarcoma "malignant neoplasm of soft tissues; thought to arise from endothelial cells of blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:57631]
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

 MP:0002051 skin papilloma "a circumscribed, benign epithelial tumor projecting from the surrounding surface" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Myo7aHdb/Myo7a4626SB
Genetic Background: involves: BALB/c * 47BS/Rl * C3HeB/FeJ * CBA/Ca

Allelic Composition: Trp53tm1Adv/Trp53+
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002052 decreased tumor incidence "less than the expected number of abnormal growths in a specific population" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Btktm1Wk/Btktm1Wk,Tectm1Welm/Tectm1Welm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Nf1tm1Tyj/?,Trp53tm1Tyj/?,Mastr129S4/SvJae/?
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6J

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Lig4tm1Icrf/Lig4tm1Icrf,Trp53tm1Tyj/Trp53+
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas) or (involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ)

Allelic Composition: Nf1tm1Tyj/?,Nstr1A/J/?,Trp53tm1Tyj/?
Genetic Background: involves: 129S2/SvPas * A/J * C57BL/6J

Allelic Composition: Nf1tm1Tyj/?,Nstr2A/J/?,Trp53tm1Tyj/?
Genetic Background: involves: 129S2/SvPas * A/J * C57BL/6J

Allelic Composition: Suds3tm1.1Rdp/Suds3+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB

Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Prkdcscid/Prkdcscid,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Chek1tm2.1Sje/Chek1+,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Chek1tm2.1Sje/Chek1tm2.1Sje,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Egfrwa2/Egfr+,Nf1tm1Fcr/Nf1+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * C57BL/6JEi * C3H/HeSnJ

Allelic Composition: Pip4k2atm1.2Lca/Pip4k2atm1.2Lca,Pip4k2bGt(Betageo)1Lca/Pip4k2b+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * 129S5/SvEvBrd

Allelic Composition: Rbm38tm1.1Xch/Rbm38tm1.1Xch,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

Allelic Composition: Rbm38tm1.1Xch/Rbm38tm1.1Xch,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

 MP:0002053 decreased incidence of induced tumors "reduced frequency of tumor incidence induced by a carcinogen or mutagen" [J:56886]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Scgb1a1-rtTA)1Jaw/0
Genetic Background: involves: 129S4/SvJae

 MP:0002060 abnormal skin morphology "malformation or atypical structure of the membranous protective covering of the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:56777]
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Allelic Composition: Grxcr1pi/Grxcr1pi
Genetic Background: B6.C3-Grxcr1pi/J

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Tg(KRT14-rtTA)208Jek/Y,Tg(tetO-KLF4)32831Rup/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6NTac * SJL

Allelic Composition: Trp53tm1Brd/Trp53+,Tg(KRT14-rtTA)208Jek/0,Tg(tetO-KLF4)32831Rup/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6NTac * SJL

 MP:0002064 seizures "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ptentm1Rdp/Pten+,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S4/SvJae * FVB/N

Allelic Composition: Trp53tm1Elee/Trp53tm1Tyj,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Ptentm1Hwu/Pten+,Trp53tm1Tyj/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Trp53tm1Elee/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Ptentm1Hwu/Pten+,Trp53tm1Elee/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0002080 prenatal lethality "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Brca1tm1Arge/Brca1tm1Arge,Brca2tm1Arge/Brca2tm1Arge
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: Brca2tm1Arge/Brca2tm1Arge,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Mdm2tm1Ypz/Mdm2tm1Ypz
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Rb1tm1Tyj/Rb1tm1Tyj,Tg(Rb1)1Blg/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Calcatm1.1(cre/ERT2)Ptch/Calca+,Trp53tm1Brn/Trp53tm1Brn,Rb1tm2Brn/Rb1tm2Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * FVB/N

Allelic Composition: Calcatm1.1(cre/ERT2)Ptch/Calca+,Trp53tm1Brn/Trp53tm1Brn,Rb1tm2Brn/Rb1tm2Brn,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S4/SvJae * BALB/c * FVB/N

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Rad50tm2Jpt/Rad50tm2Jpt,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6J

Allelic Composition: Rag2tm1Fwa/Rag2+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6J

Allelic Composition: Prkdcscid/Prkdc+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: H2afxtm1Fwa/H2afxtm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

Allelic Composition: H2afxtm1Fwa/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm2Glo/Trp53tm2Glo
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Cdkn1btm1Mlf/Cdkn1btm1Mlf,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: C57BL/6J * C3H * NIH

Allelic Composition: Cdkn1btm1Mlf/Cdkn1btm1Mlf,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: H2afxtm1Nus/H2afxtm1Nus,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: H2afxtm1Nus/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Prdm2tm1Shg/Prdm2tm1Shg,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm4Tyj/Trp53tm4Tyj
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Dcntm1Ioz/Dcntm1Ioz,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

Allelic Composition: Dcntm1Ioz/Dcn+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

Allelic Composition: Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S7-Trp53tm3.1Glo

Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Rb1tm1Tyj/Rb1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm2.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

Allelic Composition: Trp53tm3.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Tyj/Trp53tm3.1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Trp53tm1Thl/Trp53tm1Thl,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * DBA/2

Allelic Composition: Trp53bhy/Trp53bhy
Genetic Background: C57BL/6JSfdAnu-Trp53bhy/Anu

Allelic Composition: Nbntm1Jpt/Nbntm1Jpt,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Stk11tm1.1Mlfr/Stk11+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Stk11tm1.1Mlfr/Stk11+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Bhlha15tm2(Kras)Skz/Bhlha15+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Xrcc4tm2.1Fwa/Xrcc4tm2Fwa,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * SJL

Allelic Composition: Tg(Nes-cre)1Kln/0,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * SJL

Allelic Composition: Lig4tm1Icrf/Lig4tm1Icrf,Trp53tm1Tyj/Trp53+
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas) or (involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ)

Allelic Composition: Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Wrntm1Lgu/Wrntm1Lgu
Genetic Background: involves: 129S2/SvPas * BALB/c

Allelic Composition: Ppm1dtm1Lad/Ppm1dtm1Lad,Tg(IghMyc)22Bri/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129 * C57BL * FVB/N * SJL

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Tg(MMTV-KLF4)1Rup/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6NTac * FVB/NJ * SJL

Allelic Composition: Trp53tm1Tyj/Trp53tm3.1Glo
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm3.1Glo/Trp53tm3.1Glo
Genetic Background: B6.129S7-Trp53tm3.1Glo

Allelic Composition: SufuGt(XB699)Byg/Sufu+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Ptch1tm1Mps/Ptch1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm4Xu/Trp53tm4Xu
Genetic Background: Not Specified

Allelic Composition: Kat8tm2Thl/Kat8+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd

Allelic Composition: Rb1tm1.1Jyjw/Rb1tm1.1Jyjw,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Dmbt1tm1Kumc/Dmbt1tm1Kumc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6J

Allelic Composition: Dmbt1tm1Kumc/Dmbt1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6J

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Atp/0
Genetic Background: involves: 129S2/SvPas * FVB/N

Allelic Composition: Mtbptm1Glo/Mtbp+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Tg(IghMyc)22Bri/0,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129/Sv * 129X1/SvJ * C57BL * C57BL/6 * SJL

Allelic Composition: Kat5tm1Jwl/Kat5+,Tg(IghMyc)22Bri/0,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129 * C57BL * C57BL/6 * SJL

Allelic Composition: Trp53tm1Glo/Trp53tm1Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53tm1Ldo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd,Xrcc5tm1Dbr/Xrcc5tm1Dbr
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Xrcc5tm1Dbr/Xrcc5tm1Dbr
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Ccnd3tm1Pisc/Ccnd3tm1Pisc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Tg(S100b-v-erbB)4496Waw/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * DBA/2J * FVB/N

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc2tm2Pmc/Xrcc2tm2Pmc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Lig4tm1Pmc/Lig4tm1Pmc,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Lig4tm1Pmc/Lig4tm1Pmc,Trp53tm1Tyj/Trp53tm1Tyj,Xrcc2tm2Pmc/Xrcc2tm2Pmc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Lig4tm1Pmc/Lig4tm1Pmc,Trp53tm1Tyj/Trp53+,Xrcc2tm2Pmc/Xrcc2tm2Pmc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Rb1tm1Brd/Rb1+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Brca1tm2Mak/Brca1tm2Mak,Tg(Lck-cre)548Jxm/?,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

Allelic Composition: Rag1tm1Jsek/Rag1tm1Jsek,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac

Allelic Composition: Ptentm1Mro/Ptentm1Mro,Tg(KRT14-cre)8Brn/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * DBA/2J * FVB/N

Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S4/SvJae * FVB/N

Allelic Composition: Trp53tm1Elee/Trp53tm1Tyj,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * FVB/N

Allelic Composition: Nf1tm1Fcr/Nf1tm1Fcr,Trp53tm1Elee/Trp53tm1Elee,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Stk11tm1Mmt/Stk11+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ

Allelic Composition: Atrtm1Ofc/Atrtm1Ofc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Xrcc1tm1Pmc/Xrcc1tm1Pmc,Trp53tm1Tyj/Trp53+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Xrcc1tm1Pmc/Xrcc1tm1Pmc,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

Allelic Composition: Trp53tm6Xu/Trp53tm6Xu,Tg(Lck-cre)1Cwi/0
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Tg(Lck-cre)1Cwi/0
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Rev3ltm1Rwd/Rev3ltm2.1Rwd,Trp53tm1Brd/Trp53tm1Brd,Tg(MMTV-cre)1Mam/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Prkdcscid/Prkdcscid,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Trp53tm7.1Xu/Trp53tm7.1Xu
Genetic Background: Not Specified

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Rbl2tm2Tyj/Rbl2tm2Tyj,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Ssbp2tm1Lana/Ssbp2tm1Lana,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Irf1tm1Mak/Irf1tm1Mak,Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

Allelic Composition: Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Nf1tm1Par/Nf1+,Trp53tm1Tyj/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Ptentm1Hwu/Pten+,Trp53tm1Tyj/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Trp53tm1Elee/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Ptentm1Hwu/Pten+,Trp53tm1Elee/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Sirt6tm2.2Cxd/Sirt6tm2.2Cxd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * FVB/N * NIH Black Swiss

Allelic Composition: Brca2tm1Brn/Brca2tm1Cam,Krastm4Tyj/Kras+,Trp53tm3Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Trp53tm3Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Brca2tm1Cam/Brca2+,Krastm4Tyj/Kras+,Trp53tm3Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Brca2tm1Cam/Brca2tm1Brn,Tg(Pdx1-cre)6Tuv/0,Trp53tm3Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Dclre1atm1Rleg/Dclre1atm1Rleg,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

Allelic Composition: Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+,Tg(MMTV-cre)#Tfln/0,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

Allelic Composition: Trp53tm1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm4Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm3.1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Rag2tm1.1Mss/Rag2tm1.1Mss,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac

Allelic Composition: Gt(ROSA)26Sortm2Thl/Gt(ROSA)26Sor+,Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Thl/Trp53tm1Thl,Tyrc-Brd/Tyrc-Brd
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Ptgdstm1.1(cre)Gvn/Ptgds+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Espl1Gt(XL058)Byg/Espl1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (C3H/HeJ x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (CAST/EiJ x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (SJL/J x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Scgb1a1tm1(cre/ERT)Blh/Scgb1a1+,Trp53tm5Tyj/Trp53+
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Sftpctm1(cre/ERT2)Blh/Sftpc+,Trp53tm5Tyj/Trp53+
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Terttm1Rdp/Tert+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Smad4tm1Rdp/Smad4tm1Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129 * C57BL/6 * DBA/2

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Terttm3Rdp/Terttm3Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(Ly6e-MALT1)#Isg/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Lejo/Trp53tm1Lejo
Genetic Background: involves: 129

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Uimc1tm1.2Amj/Uimc1tm1.2Amj
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6

Allelic Composition: Trp53tm1Yjc/Trp53tm1Yjc
Genetic Background: B6.129S1-Trp53tm1Yjc

Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Brd/Trp53+
Genetic Background: B6.129-Trp53tm1Brd Nf1tm1Fcr

Allelic Composition: Krastm4Tyj/Kras+,Sftpctm1.1(cre/ERT2)Ptch/Sftpc+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB

Allelic Composition: Krastm1Bbd/Kras+,Trp53tm1Brd/Trp53+,Tg(Cela1-tTA)#Eps/?,Tg(tetO-cre)3Jig/?
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * FVB/N

Allelic Composition: Trp53tm1Thst/Trp53tm1Thst
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Trp53tm1Thst/Trp53+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Trp53tm1.1Thst/Trp53tm1.1Thst
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Trp53tm1.1Thst/Trp53+
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Trp53tm1Thst/Trp53tm1.1Thst
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Trp53tm1.1Thst/Trp53+,Tg(IghMyc)22Bri/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL * SJL

Allelic Composition: Trp53tm1Thst/Trp53+,Tg(IghMyc)22Bri/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL * SJL

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Rb1tm3Tyj/Rb1+,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Rb1tm3Tyj/Rb1+,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1

Allelic Composition: Exo1tm2Wed/Exo1tm2Wed,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Exo1tm3.1Wed/Exo1tm3.1Wed,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Mdm2tm1Glo/Mdm2+,Trp53tm1.1Tldo/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * BALB/c * C57BL/6

Allelic Composition: Mdm4tm1Glo/Mdm4+,Trp53tm1.1Tldo/Trp53+
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Csnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn,Tg(Vil-cre/ERT2)23Syr/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * C57BL/6 * CD-1 * DBA/2

Allelic Composition: Brca1tm2Cxd/Brca1tm2Cxd,Pkmtm1.1Mgvh/Pkmtm1.1Mgvh,Tg(MMTV-cre)4Mam/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * 129S7/SvEvBrd * FVB/N

Allelic Composition: Rasal2Gt(463C12)Cmhd/Rasal2Gt(463C12)Cmhd,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S * 129X1/SvJ * C57BL/6 * C57BL/6NCrl

Allelic Composition: Rtel1tm2.1Hdin/Rtel1tm2.1Hdin,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

Allelic Composition: Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+,Ptf1atm1.1(cre)Cvw/Ptf1a+,Tg(tetO-Kras2)12Hev/0,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J * FVB/N

Allelic Composition: Susd6tm1.1Geno/Susd6+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: C57BL/6J

Allelic Composition: Susd6tm1.1Geno/Susd6tm1.1Geno,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: C57BL/6J

Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR

Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brn/Trp53+,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N * FVB/N * ICR

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tsc1tm1Djk/Tsc1tm1Djk
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Cdh1tm2Kem/Cdh1+,Smad4tm2.1Cxd/Smad4tm2.1Cxd,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Col1a1tm4(CAG-FGFR2_iIIIb*K660N)Kkw/Col1a1+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Ren-cre)#Kwg/0
Genetic Background: involves: 129 * 129P2/OlaHsd

Allelic Composition: Rbm38tm1.1Xch/Rbm38tm1.1Xch,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

Allelic Composition: Rbm38tm1.1Xch/Rbm38tm1.1Xch,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Nf1tm1Tyj/Nf1+,Suz12Gt(Betageo)1Khe/Suz12+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Dicer1tm1Tara/Dicer1tm1Tara,Ptentm1Hwu/Ptentm1Hwu,Trp53tm2Tyj/Trp53+,Amhr2tm3(cre)Bhr/Amhr2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd

Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Trp53tm2Tyj/Trp53+,Amhr2tm3(cre)Bhr/Amhr2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd

Allelic Composition: Rps27lGt(IST11658B7)Tigm/Rps27lGt(IST11658B7)Tigm,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6N

Allelic Composition: Tg(Trp53)1Srn/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

Allelic Composition: Trp53tm1Tyj/Trp53tm1.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm1.1Umol/Trp53tm1.1Umol
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm2.1Umol/Trp53tm2.1Umol
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: 129 * 129P2/OlaHsd * FVB/N

Allelic Composition: Rb1tm2Brn/Rb1+,Trp53tm1Brn/Trp53tm1Brn,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: 129 * 129P2/OlaHsd * FVB/N

Allelic Composition: Prkar1atm1.2Lsk/Prkar1a+,Rb1tm2Brn/Rb1+,Tg(Col1a1-cre)1Kry/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Prkar1atm1.2Lsk/Prkar1a+,Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Prkar1atm1.2Lsk/Prkar1a+,Tg(Col1a1-cre)1Kry/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Trp53tm1Brn/Trp53tm1Brn,Tg(TPO-cre)1Shk/0
Genetic Background: 129.Cg-Trp53tm1Brn Ptentm2.1Ppp Tg(TPO-cre)1Shk

Allelic Composition: Braftm1Mmcm/Braf+,Trp53tm3.1Tyj/Trp53+,Tg(TPO-cre/ERT2)1139Tyj/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * C57BL/6NTac

Allelic Composition: Braftm1Mmcm/Braf+,Tg(TPO-cre/ERT2)1139Tyj/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * C57BL/6NTac

Allelic Composition: Apctm2Rak/Apc+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

Allelic Composition: Mdm4tm2Glo/Mdm4tm2.1Glo,Tg(Myh6-cre)2182Mds/0,Trp53tm1Tyj/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0002085 abnormal embryonic tissue morphology "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Brca2tm1Arge/Brca2tm1Arge,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Allelic Composition: Brca1tm1Cxd/Brca1tm1Cxd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Rev3ltm1Ndew/Rev3ltm1Ndew,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0002092 abnormal eye morphology "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Nefmtm1Jpj/Nefmtm1Jpj
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Atp/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0002106 abnormal muscle physiology "anomolous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Rb1tm1Tyj/Rb1tm1Tyj,Tg(Rb1)1Blg/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

 MP:0002109 abnormal limb morphology "abnormal development of limbs resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1Manf/Trp53tm1Manf
Genetic Background: Not Specified

 MP:0002113 abnormal skeleton development "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0002123 abnormal hematopoiesis "abnormal development of the enucleated fetal and adult erythrocytes that develop in the aorta, genital ridge and mesonephros region and later in the fetal and adult liver" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0002151 abnormal neural tube morphology/development "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cenpjtm1d(EUCOMM)Wtsi/Cenpjtm1d(EUCOMM)Wtsi,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N * FVB/NJ

 MP:0002152 abnormal brain morphology "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
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Allelic Composition: Thratm1Ven/Thra+,Thrbtm1Df/Thrbtm1Df
Genetic Background: B6.129-Thratm1Ven Thrbtm1Df

 MP:0002166 altered tumor susceptibility/resistance "greater than or less than the average number of tumors, usually a specific type, arising in a given strain when compared to controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Rbm38tm1.1Xch/Rbm38tm1.1Xch,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

Allelic Composition: Rbm38tm1.1Xch/Rbm38tm1.1Xch,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Bmp4tm1Blh/Bmp4tm3.1Blh
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Black Swiss

Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Mdm4tm2.1Glo/Mdm4tm2.1Glo,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6J

Allelic Composition: Dp(4D4Mit190-D4Mit51)1Aam/0,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Trp53tm2Holl/Trp53tm2Holl
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Trp53tm1Holl/Trp53tm2Holl
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(Gfap-cre)2Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Trp53tm1.1Mcba/Trp53tm1.1Mcba
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CD-1

Allelic Composition: Mdm4tm1Zmy/Mdm4tm1Zmy,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Manf/Trp53tm1Manf
Genetic Background: Not Specified

 MP:0002177 abnormal outer ear morphology "malformation or malfunction of any components of the auricles or external acoustic meatus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0002183 gliosis "increased growth pattern of neuroglia in a damaged area of the brain or spinal cord" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0002269 muscular atrophy "a wasting of muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0002270 abnormal alveoli morphology "any structural anomaly of the outpouching of the respiratory system where gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Krastm4Tyj/Kras+,Sftpctm1(cre/ERT2)Blh/Sftpc+,Trp53tm5Tyj/Trp53+
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6

 MP:0002357 abnormal spleen white pulp morphology "anomalous structure or formation of the splenic area consisting of lymph nodules and diffuse lymphatic tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Trp53tm1Yjc/Trp53tm1Yjc
Genetic Background: B6.129S1-Trp53tm1Yjc

Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0002362 abnormal spleen marginal zone morphology "anomalous structure of the area surrounding the marginal sinus and containing lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Trp53tm1Yjc/Trp53tm1Yjc
Genetic Background: B6.129S1-Trp53tm1Yjc

 MP:0002397 abnormal bone marrow morphology "structural anomalies in the soft tissue that fills the cavities of bones" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Hsf1tm1.1Echr/Hsf1tm1.1Echr,Tg(Zp3-cre)93Knw/0
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0002398 abnormal bone marrow cell morphology/development "anomalous structure or formation of the cells found in the bone marrow" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Mdm2tm1Mep/Mdm2tm1.1Mep
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB

 MP:0002399 abnormal pluripotent precursor cell morphology/development "anomalous structure or fomation of the cells that give rise to most types of cells necessary for fetal development" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Pknox1tm1Fbla/Pknox1tm1Fbla,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002401 abnormal lymphopoiesis "atypcial formation of lymphocytes and plasma cells from lymphoid stem cells which develop from the pluripotent hematopoietic stem cells in the bone marrow; these lymphoid stem cells differentiate into T-lymphocytes; B-lymphocytes; plasma cells; or NK-cells (natural killer cells), depending on the organ or tissues to which they migrate" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0002404 intestinal adenoma "benign tumors of the small and large intestine" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

 MP:0002407 abnormal double-negative T cell "anomalous structure, development, or number of the subset of T cells found in the thymus that express neither CD4 nor CD8" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Tcrbetm1Che/Tcrbetm1Che,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Tcrbetm1Che/Tcrbetm1Che,Tcrdtm1Mom/Tcrdtm1Mom,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0002408 abnormal double-positive T cell "anomalous development or number of the subset of T cells found in the thymus that express both CD4 and CD8" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tcrbetm1Che/Tcrbetm1Che,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0002413 abnormal megakaryoblast morphology/development "anomalous structure or development of the progenitor cells of the thrombocytic (platelet) line of cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

 MP:0002582 disorganized extraembryonic tissue "a lack of the regular arrangement of the membranes involved with the embryo s protection and nutrition" [J:40596, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gusbmps/Gusbmps
Genetic Background: involves: C57BL/6By

 MP:0002590 increased mean corpuscular volume "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Smim3tm1Anjm/Smim3+,Cd74tm1Anjm/Cd74+,Lmo2tm2(cre)Thr/Lmo2+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

 MP:0002619 abnormal lymphocyte morphology/development "anomalous structure, differentiation, or number of the white blood cells formed in the body s lymphoid tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

 MP:0002627 teratoma "neoplasms composed of multiple tissue types; includes types not found in tissue in which lesion arises" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: H2afxtm1Fwa/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53Bbl/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53Bbl/Anu

Allelic Composition: Nbntm1Jpt/Nbntm1Jpt,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Rb1tm1.1Jyjw/Rb1tm1.1Jyjw,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

Allelic Composition: Sirt1tm1.1Cxd/Sirt1+,Trp53tm1Brd/Trp53+
Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB/N)

Allelic Composition: Irf1tm1Mak/Irf1tm1Mak,Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

Allelic Composition: Trp53tm1Thst/Trp53tm1Thst
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Rtel1tm2.1Hdin/Rtel1tm2.1Hdin,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0002628 fatty liver "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

Allelic Composition: Rbm38tm1.1Xch/Rbm38tm1.1Xch,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

 MP:0002633 persistent truncus arteriosis "complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0002639 micrognathia "abnormally reduced size of the jaws, especially of the mandible" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Atrtm1Ofc/Atrtm1Ofc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

 MP:0002661 abnormal corpus "anomalous structure of the body of the epididymis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Mapttm1(EGFP)Klt/Mapttm1(EGFP)Klt
Genetic Background: B6.129S4-Mapttm1(EGFP)Klt

 MP:0002663 failure to form blastocele "developmental anomaly resulting in the absence of the cavity in the blastula of the developing embryo" [cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:19904]
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Allelic Composition: Emg1tm1Hdin/Emg1tm1Hdin,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S * 129S2/SvPas * 129X1/SvJ * CD-1 * ICR

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
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Allelic Composition: Ing2tm1.1Ccha/Ing2tm1.1Ccha,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0002700 opacity of vitreous body "milky or cloudy eyeball that is impervious to light" [J:30249]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129S2-Trp53tm1Tyj/J

 MP:0002703 abnormal renal tubules "anomalous structure or development of the loops of Henle and collecting ducts in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

 MP:0002712 increased circulating glucagon level "greater than normal blood concentration of this peptide hormone" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Ren-cre)#Kwg/0
Genetic Background: involves: 129 * 129P2/OlaHsd

 MP:0002724 enhanced wound healing "increased ability to self-repair and close wounds" [dlb:Donna Burkart , Mouse Genome Informatics Curator, J:42016]
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Allelic Composition: Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

 MP:0002792 abnormal retinal vascularization "malformation or disorganization of the blood vessels supplying the retina" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Glis3tm1Hiha/Glis3tm1Hiha
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129S2-Trp53tm1Tyj/J

 MP:0002833 increased heart weight "greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

 MP:0002840 abnormal lens fibers morphology "structural anomaly of the elongated cells of the crystalline lens of the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Atf4tm1Jml/Atf4tm1Jml
Genetic Background: involves: 129X1/SvJ

 MP:0002864 abnormal ocular fundus morphology "malformation of the posterior concave interior of the eye, consisting of the retina, the choroid, the posterior segment of the sclera, the optic disk, and blood vessels, visible by an ophthalmoscope" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129S2-Trp53tm1Tyj/J

 MP:0002875 decreased erythrocyte count "reduced number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

Allelic Composition: Smim3tm1Anjm/Smim3+,Cd74tm1Anjm/Cd74+,Lmo2tm2(cre)Thr/Lmo2+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mdm2tm1Glo/Mdm2+,Trp53tm2Wahl/Trp53tm2Wahl
Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6

 MP:0002877 abnormal melanocyte morphology "malformation of the cells that produce pigment " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB

Allelic Composition: Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh,Trp53tm1Brn/Trp53tm1Brn,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Cdkn2atm2.1Nesh/Cdkn2a+,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB

 MP:0002908 delayed wound healing "longer time requirement for the ability to self-repair and close wounds than normal" [J:63037]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002947 hemangioma "proliferation of blood vessels leading to a mass that resembles a neoplasm" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:87544]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129S4/SvJae * FVB/N * SKH1

 MP:0002957 intestinal adenocarcinoma "malignant neoplasm of epithelial cells in the intestine" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Rb1tm1.1Jyjw/Rb1tm1.1Jyjw,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

Allelic Composition: Cdh1tm2Kem/Cdh1+,Smad4tm2.1Cxd/Smad4tm2.1Cxd,Trp53tm1Brn/Trp53tm1Brn,Tg(Vil-cre)20Syr/0
Genetic Background: involves: 129 * C57BL/6 * DBA/2

Allelic Composition: Smad4tm2.1Cxd/Smad4tm2.1Cxd,Trp53tm1Brn/Trp53tm1Brn,Tg(Vil-cre)20Syr/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

 MP:0002989 small kidney "reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0003010 decreased mortality induced by ionizing radiation "reduced sensitivity to lethal doses of ionizing radiation such as ultraviolet light, X-rays, or gamma rays" [smb:Susan M. Bello , Mouse Genome Informatics Curator, J:88888]
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Allelic Composition: Mdm2tm1Mep/Mdm2tm1.1Mep
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB

Allelic Composition: Cdkn1atm1Hpw/Cdkn1a+,Trp53tm2Wahl/Trp53tm2Wahl
Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Rbm38tm1.1Xch/Rbm38tm1.1Xch,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

 MP:0003046 liver cirrhosis "liver disease in which the occurrence of fibrotic nodules cause diffuse damage to parenchymal cells, disruptions in microcirculation, vascular anatomy and hepatic architecture, resulting in hepatic dysfunction and ultimately, hepatic failure" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

 MP:0003077 abnormal cell cycle "failure to progress or abnormal progression through the stages of of the cell cycle" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91266]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S7-Trp53tm3.1Glo

Allelic Composition: Trp53tm1Wahl/Trp53tm1Wahl
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Mdm4Gt(VICTR20)7Lex/Mdm4Gt(VICTR20)7Lex,Trp53tm1Wahl/Trp53tm1Wahl
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

Allelic Composition: Mdm2tm1Glo/Mdm2+,Trp53tm1Wahl/Trp53tm1Wahl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mdm4Gt(VICTR20)7Lex/Mdm4+,Trp53tm1Wahl/Trp53tm1Wahl
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

Allelic Composition: Mdm2tm1Glo/Mdm2+,Mdm4Gt(VICTR20)7Lex/Mdm4+,Trp53tm1Wahl/Trp53tm1Wahl
Genetic Background: involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm5Tyj/Trp53tm5Tyj
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm3Wahl/Trp53tm3Wahl
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Mdm4Gt(VICTR20)7Lex/Mdm4Gt(VICTR20)7Lex,Trp53tm3Wahl/Trp53tm3Wahl
Genetic Background: involves: 129S4/SvJae * 129S5/SvEvBrd

Allelic Composition: Mdm2tm1Glo/Mdm2+,Trp53tm3Wahl/Trp53tm3Wahl
Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd

Allelic Composition: Mdm2tm1Glo/Mdm2+,Mdm4Gt(VICTR20)7Lex/Mdm4+,Trp53tm3Wahl/Trp53tm3Wahl
Genetic Background: involves: 129

Allelic Composition: Trp53tm1Att/Trp53tm1Att
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Mlh/Trp53tm1Mlh
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Trp53tm2Att/Trp53tm2Att
Genetic Background: either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C57BL/6)

Allelic Composition: Telo2tm1Tdl/Telo2tm1.1Tdl,Trp53tm1Tyj/Trp53tm1Tyj,Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S2/SvPas * C57BL/6J

Allelic Composition: Rb1tm1Tyj/Rb1tm1Tyj,Tg(Rb1)1Blg/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm2.1Snj/Trp53tm2.1Snj
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm2.1Snj/Trp53+
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm2.1Wgu/Trp53tm2.1Wgu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0003084 abnormal skeletal muscle fiber morphology "anomalous structure of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [smb:Susan M. Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Rb1tm1Tyj/Rb1tm1Tyj,Tg(Rb1)1Blg/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

 MP:0003091 abnormal cell migration "defect in the movement of cells during developmental processes" [smb:Susan M. Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

 MP:0003111 abnormal nucleus morphology "abnormalities in the nucleus and/or its surrounding membrane" [J:91473, smb:Susan M. Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Rnaseh2btm1a(EUCOMM)Wtsi/Rnaseh2btm1a(EUCOMM)Wtsi,Trp53tm1Mlh/Trp53tm1Mlh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N

 MP:0003155 abnormal telomere length "abnormal length of the terminal section of a chromosome which has a specialized structure and which is involved in chromosomal replication and stability; normal length is a few hundred base pairs" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Terttm1Rdp/Terttm1Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Terttm3Rdp/Terttm3Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Mdm2tm1Glo/Mdm2+,Trp53tm1.1Tldo/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * BALB/c * C57BL/6

Allelic Composition: Mdm4tm1Glo/Mdm4+,Trp53tm1.1Tldo/Trp53+
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

 MP:0003179 decreased platelet count "fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

Allelic Composition: Smim3tm1Anjm/Smim3+,Cd74tm1Anjm/Cd74+,Lmo2tm2(cre)Thr/Lmo2+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mdm2tm1Glo/Mdm2+,Trp53tm2Wahl/Trp53tm2Wahl
Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0003202 abnormal neuron apoptosis "change in the timing or the number of neurons undergoing programmed cell death" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Emx1tm1(cre)Krj/Emx1+,Topbp1tm1Pmc/Topbp1tm1Pmc
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0003204 decreased neuron apoptosis "decrease in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission]
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Allelic Composition: Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc2tm1Pmc/Xrcc2tm1Pmc
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

 MP:0003205 testicular atrophy "wasting of the male reproductive glands resulting in reduced size" [RGD:Rat Genome Database submission]
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Allelic Composition: Trp53tm2Xu/Trp53tm2Xu,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

 MP:0003207 decreased sensitivity to gamma-irradiation "decreased incidence of cell death following high levels of gamma-irradiation" [J:92917, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm4Tyj/Trp53tm4Tyj
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S7-Trp53tm3.1Glo

Allelic Composition: Trp53tm1Gev/Trp53tm1Gev
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Trp53tm2.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm3.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Wahl/Trp53tm1Wahl
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm3Wahl/Trp53tm3Wahl
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Att/Trp53tm1Att
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Trp73tm2Mak/Trp73tm2Mak
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Trp53tm1.1Awbr/Trp53tm1.1Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm4Att/Trp53tm4Att
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1.1Wgu/Trp53tm1.1Wgu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Trp53tm1Thst/Trp53tm1Thst
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Trp53tm1.1Thst/Trp53tm1.1Thst
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Trp53tm1Tyj/Trp53tm1.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

 MP:0003223 decreased cardiomyocyte apoptosis "decrease in the number of cardiac muscle cells undergoing programmed cell death" [RGD:Rat Genome Database submission]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NCrj

 MP:0003236 abnormal lens capsule morphology "malformation in the elastic, clear, membrane-like structure, that is outer most layer of the lens" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93301]
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Allelic Composition: Nefmtm1Jpj/Nefmtm1Jpj
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003237 abnormal lens epithelium morphology "malformation in the one or more of the layers of epithelial cells in the lens" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93301]
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Allelic Composition: Thratm1Ven/Thra+,Thrbtm1Df/Thrbtm1Df
Genetic Background: B6.129-Thratm1Ven Thrbtm1Df

 MP:0003269 colonic polyps "abnormal tissue masses that protrude into the lumen of the colon and are tethered to the wall of the colon" [ncbi:Matthew Mailman, NCBI request, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Stk11tm1.1Mlfr/Stk11+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

 MP:0003270 intestinal obstruction "any impediment, blockage, or reversal of the normal flow of the intestinal contents toward the anus " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0003277 esophageal papilloma "benign epithelial tumor of the esophagus" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0003299 gastric polyps "abnormal tissue masses that protrude into the lumen of the stomach and are tethered to the wall of the colon" [ncbi:Matthew Mailman, NCBI request, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Stk11tm1.1Mlfr/Stk11+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

 MP:0003324 liver adenoma "benign epithelial neoplasm of the liver" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Gt(ROSA)26Sortm2(sb11)Njen/Gt(ROSA)26Sor+,Trp53tm3Tyj/Trp53+,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+,TgTn(sb-T2/Onc)68Dla/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

 MP:0003331 hepatocellular carcinoma "malignant neoplasm arising from liver cells" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Trp53tm3.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Bhlha15tm2(Kras)Skz/Bhlha15+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Gt(ROSA)26Sortm2(sb11)Njen/Gt(ROSA)26Sor+,Trp53tm3Tyj/Trp53+,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+,TgTn(sb-T2/Onc)68Dla/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N

Allelic Composition: Stk11tm1Mmt/Stk11+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Rasal2Gt(463C12)Cmhd/Rasal2Gt(463C12)Cmhd,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S * 129X1/SvJ * C57BL/6 * C57BL/6NCrl

 MP:0003335 exocrine pancreatic insufficiency "reduced or absent function of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [ncbi:Matthew Mailman, NCBI request, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Brca2tm1Cam/Brca2tm1Brn,Tg(Pdx1-cre)6Tuv/0,Trp53tm3Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N

 MP:0003365 glucagonoma "a pancreatic islet alpha cell adenoma that secretes excess glucagon" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Ren-cre)#Kwg/0
Genetic Background: involves: 129 * 129P2/OlaHsd

 MP:0003402 decreased liver weight "reduced average weight of the bile-secreting exocrine gland" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003446 renal hypoplasia "decreased cell number in the kidney leading to reduced size" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003447 reduced tumor growth/size "less than expected development of tumorous growth when compared to controls" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65383]
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Allelic Composition: Cdkn2atm1Cjs/Cdkn2a+
Genetic Background: involves: 129X1/SvJ * C57BL/6 * NIH/OlaHsd

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Scgb1a1-rtTA)1Jaw/0
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm3.1Glo/Trp53tm4Glo,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Terttm1Rdp/Terttm1Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

 MP:0003448 altered tumor morphology "changes in the expected pathology for a given tumor type compared to controls" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brd/Trp53+,Tg(Rbp3-cre)1Brn/0
Genetic Background: involves: 129 * 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Rb1tm1Tyj/Rb1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm3Glo/Trp53+,Tg(KRT5-cre/PGR)1Der/?
Genetic Background: involves: 129/Sv * C57BL/6 * FVB * ICR

Allelic Composition: Sirt1tm1.1Cxd/Sirt1+,Trp53tm1Brd/Trp53+
Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB/N)

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Tyj/Trp53+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Lig4tm1Pmc/Lig4tm1Pmc,Trp53tm1Tyj/Trp53+,Xrcc2tm2Pmc/Xrcc2tm2Pmc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Tg(KRT14-cre)8Brn/0,Tg(KRT5-Akt1*)Jmpa/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * DBA/2J * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Scgb1a1-rtTA)1Jaw/0
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Chek1tm2.1Sje/Chek1tm2.1Sje,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Chek1tm2.1Sje/Chek1+,Trp53tm1Brn/Trp53+,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Trp53tm1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm3.1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Brca1tm1Brn/Brca1tm1.1Jjon,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N

Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N

Allelic Composition: Palb2tm1.1Dli/Palb2tm1.1Dli,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)1Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CBA

 MP:0003507 abnormal ovary physiology "anomaly or loss either the production of female germ cells or the endocrine cells for the production of estrogen and progesterone" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: KitW-v/KitW-v,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N

 MP:0003570 uterine leiomyoma "a benign tumor derived from the smooth muscle tissue of the uterus" [ncbi:Matthew Mailman, NCBI request, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

 MP:0003574 abnormal oviduct morphology "malformation of the tube through which the ova pass from the ovary to the uterus" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Tg(Krt18-EGFP,-TAg121)36Ysng/0,Trp53tm1Brn/Trp53tm2Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N

 MP:0003579 ovarian carcinoma 
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Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Tg(Krt18-EGFP,-TAg121)36Ysng/0,Trp53tm1Brn/Trp53tm2Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N

Allelic Composition: Dicer1tm1Tara/Dicer1tm1Tara,Ptentm1Hwu/Ptentm1Hwu,Trp53tm2Tyj/Trp53+,Amhr2tm3(cre)Bhr/Amhr2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd

Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Trp53tm2Tyj/Trp53+,Amhr2tm3(cre)Bhr/Amhr2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd

 MP:0003587 ureter obstruction "any impediment, blockage, or reversal of the normal flow of the urine towards the bladder" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Brca1tm2Cxd/Brca1tm2Cxd,Tg(MMTV-cre)4Mam/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB

 MP:0003606 kidney failure "cessation of renal function" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Trp53tm1Thl/Trp53tm1Thl,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * DBA/2

 MP:0003607 abnormal prostate physiology "malfunction of the gland in males that secretes part of the seminiferous fluid" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Brn/Trp53+,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2

 MP:0003632 abnormal nervous system morphology 
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Allelic Composition: Emx1tm1(cre)Krj/Emx1+,Topbp1tm1Pmc/Topbp1tm1Pmc
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0003643 spleen atrophy "wasting of the spleen resulting in reduced size" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Mdm2tm1Glo/Mdm2+,Trp53tm2Wahl/Trp53tm2Wahl
Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6

 MP:0003667 hemangiosarcoma "a malignant tumor characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and appear as irregular blood-filled or lumpy sacs that are typically filled with blood; rupture of the tumor can cause rapid death from bleeding" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:53511]
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Allelic Composition: Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Dcntm1Ioz/Dcntm1Ioz,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

Allelic Composition: Trp53Bbl/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53Bbl/Anu

Allelic Composition: Trp53bhy/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53bhy/Anu

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Irf1tm1Mak/Irf1tm1Mak,Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

Allelic Composition: Tg(TRP53*R72P)7Dgj/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * FVB

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Rnf168Gt(405F11)Cmhd/Rnf168Gt(405F11)Cmhd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Rnf168Gt(156B6)Cmhd/Rnf168Gt(156B6)Cmhd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Trp53tm1.1Thst/Trp53tm1.1Thst
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Tg(Mdm2)1Snj/0,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Nf1tm1Tyj/Nf1+,Suz12Gt(Betageo)1Khe/Suz12+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0003674 oxidative stress "condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NCrj

Allelic Composition: Trp53tm1Thst/Trp53tm1Thst
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003701 elevated level of sister chromatid exchange "increased number of crossovers between sister chromatids during meiosis resulting in increased numbers of reciprocal exchanges of DNA between the two chromosomes" [hdene:Howard Dene , Mouse Genome Informatics Curator, J:97667]
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Allelic Composition: Pot1atm1Schg/Pot1atm1.1Schg,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6

 MP:0003702 abnormal chromosome morphology "anomalies in the structure of the compact, intertwined molecules of DNA found in the nucleus which carry genetic information " [hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Pot1atm1Schg/Pot1atm1.1Schg,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Brca2tm1Mak/Brca2tm2Mak,Trp53tm1Brd/Trp53tm1Brd,Tg(Lck-cre)548Jxm/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Chek1tm2.1Sje/Chek1+,Trp53tm1Brn/Trp53+,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Rag2tm1.1Mss/Rag2tm1.1Mss,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Terttm3Rdp/Terttm3Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

 MP:0003717 pallor "an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

 MP:0003720 abnormal neural tube closure "abnormal invagination and fusion of the neuroepithelial layer in early development" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:99099]
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Allelic Composition: Rnaseh2btm1a(EUCOMM)Wtsi/Rnaseh2btm1a(EUCOMM)Wtsi,Trp53tm1Mlh/Trp53tm1Mlh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N

Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0003721 increased tumor growth/size "greater than expected development of tumorous growth when compared to controls" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Cdkn2atm1Cjs/Cdkn2atm1Cjs,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * NIH/OlaHsd

Allelic Composition: Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)105Ayn/0
Genetic Background: FVB.Cg-Trp53tm1Brn Rb1tm2Brn Tg(MMTV-cre)105Ayn

Allelic Composition: Gt(ROSA)26Sortm2Thl/Gt(ROSA)26Sor+,Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Thl/Trp53tm1Thl,Tyrc-Brd/Tyrc-Brd
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6

Allelic Composition: Krastm5Tyj/Kras+,Trp53tm1.1Dgk/Trp53tm1.1Dgk
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+,Uimc1tm1.2Amj/Uimc1tm1.2Amj
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6

 MP:0003750 mouth tumor "presence of abnormal rapidly proliferating cells in the mouth, usually in the form of a distinct mass" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Palb2tm1.1Dli/Palb2tm1.1Dli,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)1Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CBA

Allelic Composition: Rasal2Gt(463C12)Cmhd/Rasal2Gt(463C12)Cmhd,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S * 129X1/SvJ * C57BL/6 * C57BL/6NCrl

 MP:0003751 oral leukoplakia "white precancerous lesions of the mucous membranes of the oral cavity" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Trim71Gt(XD089)Byg/Trim71Gt(XD089)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

 MP:0003763 abnormal thymus physiology "anomalous function of the primary lymphoid organ that is required for immune system development" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm7.1Xu/Trp53tm7.1Xu
Genetic Background: Not Specified

Allelic Composition: Trp53tm7.1Xu/Trp53+
Genetic Background: Not Specified

Allelic Composition: Trp53tm2.1Snj/Trp53tm2.1Snj
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0003786 premature aging "earlier than normal occurence of the normal signs of aging" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:97764]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Atrtm1Ofc/Atrtm1Ofc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

Allelic Composition: Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0003789 osteosarcoma "malignant neoplasm derived from bone" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53Bbl/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53Bbl/Anu

Allelic Composition: Trp53bhy/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53bhy/Anu

Allelic Composition: Stk11tm1.1Mlfr/Stk11+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Brca2tm1Kamc/Brca2tm1Kamc,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Brca2tm1Mak/Brca2tm2Mak,Trp53tm1Brd/Trp53tm1Brd,Tg(Lck-cre)548Jxm/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Rev3ltm1Rwd/Rev3ltm2.1Rwd,Trp53tm1Brd/Trp53+,Tg(MMTV-cre)1Mam/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Tg(TRP53)4Dgj/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * FVB

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Mdm2tm4.1Glo/Mdm2tm4.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm4.1Glo Trp53tm3.1Glo

Allelic Composition: Trp53tm1.1Awbr/Trp53tm1.1Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Ptgdstm1.1(cre)Gvn/Ptgds+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Rb1tm3Tyj/Rb1+,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Rb1tm3Tyj/Rb1+,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6J * CD-1 * FVB/N

Allelic Composition: Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1

Allelic Composition: Tg(Mdm2)1Snj/0,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Ptch1tm1Yy/Ptch1+,Trp53tm1Brd/Trp53+,Tg(BGLAP-cre)1Clem/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/NJ

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: 129 * 129P2/OlaHsd * FVB/N

Allelic Composition: Rb1tm2Brn/Rb1+,Trp53tm1Brn/Trp53tm1Brn,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: 129 * 129P2/OlaHsd * FVB/N

Allelic Composition: Prkar1atm1.2Lsk/Prkar1a+,Rb1tm2Brn/Rb1+,Tg(Col1a1-cre)1Kry/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Prkar1atm1.2Lsk/Prkar1a+,Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Prkar1atm1.2Lsk/Prkar1a+,Tg(Col1a1-cre)1Kry/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N

 MP:0003795 abnormal bone structure 
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0003809 abnormal hair shaft morphology "irregular or unusual structure of the cuticle, and/or cortex and/or medulla of a hair" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR

 MP:0003886 abnormal embryonic epiblast morphology "anomaly in the development/organization of the tissue that gives rise to the ectoderm, endoderm and mesoderm of the embryo proper" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Pknox1tm1Fbla/Pknox1tm1Fbla,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0003918 decreased kidney weight "reduced heft of the organs responsible for urine secretion" [RGD:Rat Genome Database submission]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003927 enhanced cellular glucose import "improved ability of a cell to take in glucose from the environment" [RGD:Rat Genome Database submission]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Brca1tm1Arge/Brca1tm1Arge,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Allelic Composition: Eloatm1Aso/Eloatm1Aso,Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: 129S/SvEv * C57BL/6 * CBA

Allelic Composition: Kat2atm1Roth/Kat2atm1Roth,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Mdm4tm1Glo/Mdm4tm1Glo,Trp53tm1Adv/Trp53tm1Adv
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Brca1tm1Mak/Brca1tm1Mak,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

Allelic Composition: Pknox1tm1Fbla/Pknox1tm1Fbla,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Mdm4Gt(VICTR20)7Lex/Mdm4+,Trp53tm1.1Xlu/Trp53tm1.1Xlu
Genetic Background: involves: 129S5/SvEvBrd * 129S6/SvEvTac * C57BL/6 * FVB/N

Allelic Composition: Cops6Gt(RRI087)Byg/Cops6Gt(RRI087)Byg,Trp53tm1Glo/Trp53tm1Glo
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Rnaseh2btm1a(EUCOMM)Wtsi/Rnaseh2btm1a(EUCOMM)Wtsi,Trp53tm1Mlh/Trp53tm1Mlh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N

 MP:0003992 increased mortality induced by ionizing radiation "greater sensitivity to doses of ionizing radiation that include ultraviolet light, X-rays, or gamma rays" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

Allelic Composition: Mdm2tm1Glo/Mdm2+,Trp53tm2Wahl/Trp53tm2Wahl
Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6

 MP:0004023 abnormal chromosome number "chromosome count is other than the expected diploid chromosome number" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Brca1tm1Cxd/Brca1tm1Cxd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm5Tyj/Trp53tm5Tyj
Genetic Background: involves: 129S4/SvJae

 MP:0004024 aneuploidy "chromosome count is not an exact multiple of the haploid number " [llw2:Linda Washburn , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Suds3tm1.1Rdp/Suds3+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB

Allelic Composition: Chek1tm2.1Sje/Chek1+,Trp53tm1Brn/Trp53+,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Rag2tm1.1Mss/Rag2tm1.1Mss,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac

Allelic Composition: Espl1Gt(XL058)Byg/Espl1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg

Allelic Composition: Rps27lGt(IST11658B7)Tigm/Rps27lGt(IST11658B7)Tigm,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6N

 MP:0004025 polyploidy "more than two chromosome sets are present" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Tg(MMTV-AURKA)#Cxd/?,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * FVB/N

Allelic Composition: Rb1tm1Tyj/Rb1tm1Tyj,Tg(Rb1)1Blg/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

 MP:0004028 chromosome breakage "chromosome instability in the from of increased frequency of spontaneous breakage with or without rearrangements" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Bard1tm1Thl/Bard1tm1Thl,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S1/Sv * 129S2/SvPas

Allelic Composition: Pot1atm1Schg/Pot1atm1.1Schg,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6

 MP:0004029 spontaneous chromosome breakage "chromosome breakage due to inherent instability of chromosomes" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Brca1tm1Cxd/Brca1tm1Cxd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm4Xu/Trp53tm4Xu
Genetic Background: Not Specified

Allelic Composition: Trp53tm5Xu/Trp53tm5Xu
Genetic Background: Not Specified

Allelic Composition: Brca1tm2Mak/Brca1tm2Mak,Tg(Lck-cre)548Jxm/?,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

Allelic Composition: Rag1tm1Jsek/Rag1tm1Jsek,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac

Allelic Composition: Ightm2Cgn/Ightm2Cgn,Igktm1Rsky/Igktm1Rsky,Trp53tm1Tyj/Trp53tm1Tyj,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac

 MP:0004045 abnormal cell cycle checkpoint function "anomaly in the amount of time spent at the points in the cell cycle (end of G1 phase, end of G2 phase, and during metaphase) which prevent the cell from progressing to the next phase when conditions are unfavorable" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Mdm4Gt(VICTR20)7Lex/Mdm4Gt(VICTR20)7Lex,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd

Allelic Composition: Trp53tm1Att/Trp53tm1Att
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm4Xu/Trp53tm4Xu
Genetic Background: Not Specified

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm7.1Xu/Trp53tm7.1Xu
Genetic Background: Not Specified

Allelic Composition: Trp53tm7.1Xu/Trp53+
Genetic Background: Not Specified

 MP:0004046 abnormal mitosis "anomaly in the process of cell division including both division of the nucleus (karyokinesis) and the cytoplasm (cytokinesis) " [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Cenpjtm1d(EUCOMM)Wtsi/Cenpjtm1d(EUCOMM)Wtsi,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N * FVB/NJ

 MP:0004097 abnormal cerebellar cortex morphology "any structural anomaly of the thin mantle of gray matter that covers the surface of each cerebral hemisphere, including the six layers of nerve cells and the nerve pathways that connect them; together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0004174 abnormal spine curvature "deviation from the typical S-shape of the spine" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004179 transmission ratio distortion "the occurence of an allele or haplotype in the offspring of an organism at skewed Mendelian ratios" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Map1btm1Prop/Map1btm1Prop
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Motp1CE/J/Motp1CE/J,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129-Trp53tm1Tyj/J * CE/J

 MP:0004180 failure of initiation of embryo turning "failure to begin the axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (E8.5-E9.5)" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Brca1tm1Mak/Brca1tm1Mak,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0004201 fetal growth retardation "slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rbm24tm1.1Xch/Rbm24tm1.1Xch,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

 MP:0004207 squamous cell carcinoma "a carcinoma that arises from stratified squamous epithelium that occurs in sites where glandular or columnar epithelium is normally present, such as the skin, esophagus, lungs and cervix" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm3.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Cdh1tm1Jjon/Cdh1+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/?
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * FVB * ICR

Allelic Composition: Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Tg(KRT14-cre)8Brn/0,Tg(KRT5-Akt1*)Jmpa/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * DBA/2J * FVB/N

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Mdm2tm4.1Glo/Mdm2tm4.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm4.1Glo Trp53tm3.1Glo

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)105Ayn/0
Genetic Background: FVB.Cg-Trp53tm1Brn Tg(MMTV-cre)105Ayn

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)105Ayn/0
Genetic Background: FVB.Cg-Trp53tm1Brn Rb1tm2Brn Tg(MMTV-cre)105Ayn

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Tg(Mdm2)1Snj/0,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Cdh1tm2Kem/Cdh1+,Smad4tm2.1Cxd/Smad4tm2.1Cxd,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

 MP:0004208 basal cell carcinoma "a slow-growing, invasive, but usually non-metastasizing neoplasm that originates from basal keratinocytes in the epidermis" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brn/Trp53+,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR

 MP:0004227 increased cellular sensitivity to ionizing radiation "increased incidence of cell death following exposure to high levels of ionizing radiation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm3Xu/Trp53tm3Xu
Genetic Background: Not Specified

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * BALB/c

Allelic Composition: Ing1Gt(OST206270)Lex/Ing1Gt(OST206270)Lex,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Ightm2Cgn/Ightm2Cgn,Igktm1Rsky/Igktm1Rsky,Trp53tm1Tyj/Trp53tm1Tyj,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac

Allelic Composition: Trp53tm2.1Dgj/Trp53tm2.1Dgj
Genetic Background: involves: SKH

 MP:0004228 decreased cellular sensitivity to ionizing radiation "decreased incidence of cell death following exposure to high levels of ionizing radiation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Xu/Trp53tm1Xu
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Snj/Trp53tm1Snj
Genetic Background: involves: C57BL/6

Allelic Composition: Brca2tm1Mak/Brca2tm2Mak,Trp53tm1Brd/Trp53tm1Brd,Tg(Lck-cre)548Jxm/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * FVB/N

Allelic Composition: Trp53tm1.1Dgj/Trp53tm1.1Dgj
Genetic Background: involves: SKH

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Trp53tm2.1Snj/Trp53tm2.1Snj
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm2.1Snj/Trp53+
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0004261 abnormal embryonic neuroepithelium morphology "any structural anomaly in the epithelial cell layer that lines the neural tube and develops into the nervous system and into the neural crest cells" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition", MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Cenpjtm1d(EUCOMM)Wtsi/Cenpjtm1d(EUCOMM)Wtsi,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N * FVB/NJ

 MP:0004263 abnormal limb posture "atypical position of the limbs compared to the normal carriage of the body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0004351 short humerus "reduced length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0004390 abnormal bronchoalveolar duct junctions "any structural anomaly of the branch point connecting the respiratory bronchioles to the alveolar ducts" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Krastm4Tyj/Kras+,Scgb1a1tm1(cre/ERT)Blh/Scgb1a1+,Trp53tm5Tyj/Trp53+
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6

 MP:0004478 testicular teratoma "neoplasms found in the testis that are composed of multiple tissue types; includes types not normally found in tesis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Rb1tm1.1Jyjw/Rb1tm1.1Jyjw,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

 MP:0004499 increased incidence of chemically-induced tumors "higher than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Terttm1Rdp/Terttm1Rdp,Trp53tm1Tyj/Trp53+
Genetic Background: B6.Cg-Trp53tm1Tyj Terttm1Rdp

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm3Glo/Trp53+,Tg(KRT5-cre/PGR)1Der/?
Genetic Background: involves: 129/Sv * C57BL/6 * FVB * ICR

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm3Glo,Tg(KRT5-cre/PGR)1Der/?
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * FVB * ICR

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Tyj/Trp53+,Xpatm1Hvs/Xpatm1Hvs
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0004500 increased incidence of ionizing radiation-induced tumors "higher than normal frequency of tumor incidence induced by radiation in which the individual particle or photon carries sufficient energy to completely remove an electron from its orbit; common types of this radiation include gamma-rays and X-rays" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Sh2d1atm1Cpt/Sh2d1atm1Cpt
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1.1Awbr/Trp53tm1.1Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cops6Gt(RRI087)Byg/Cops6+,Trp53tm1Glo/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Trp53tm1Tyj/Trp53+,Uimc1tm1.2Amj/Uimc1tm1.2Amj
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6

 MP:0004501 increased incidence of UV-induced tumors "higher than normal frequency of tumor incidence induced by exposure to ultraviolet light" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tarbp2tm1.2Dzw/Tarbp2tm1.2Dzw
Genetic Background: involves: 129 * FVB/N

 MP:0004502 decreased incidence of chemically-induced tumors "lower than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/?
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * FVB * ICR

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd
Genetic Background: NIHOla.129S7-Trp53tm1Brd

Allelic Composition: Tg(KRT14-Birc5)19Gros/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6

 MP:0004510 myositis "inflammation of skeletal muscle; local accumulation of fluid, plasma proteins, and leukocytes in the striated muscle" [MESH:C05.651.594]
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Allelic Composition: Ryr2tm1(CAG-KRAS*G12V,-lacZ)Nobs/Ryr2tm1(CAG-KRAS*G12V,-lacZ)Nobs,Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: 129X1/SvJ * C57BL/6 * CBA

 MP:0004624 abnormal thoracic cage "any structural anomaly of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Nabp2tm1.2Nfel/Nabp2tm1.2Nfel,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N * SJL

 MP:0004684 intervertebral disk degeneration "retrogressive pathological change of the cartilaginous and gelatinous structure found between vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0004701 decreased circulating insulin-like growth factor I level "reduced blood concentration of this polypeptide hormone with growth-regulating, insulin-like, and mitogenic activities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: B6.129S7-Trp53tm1Ldo

 MP:0004734 small thoracic cavity "reduced size of the cavity in the vertebrate body enclosed by the ribcage between the diaphragm and the neck, and contains the lungs, heart, thoracic aorta, pulmonary artery and its branches, thymus gland, and the respiratory airway" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Atrtm1Ofc/Atrtm1Ofc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

 MP:0004809 increased hematopoietic stem cell number "greater cell count of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; these give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hey1tm1Kkb/Hey1tm1Kkb,Heyltm1Kkb/Heyltm1Kkb
Genetic Background: B6.Cg-Hey1tm1Kkb Heyltm1Kkb

Allelic Composition: Trp53tm1Tyj/Trp53tm1.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

 MP:0004810 decreased hematopoietic stem cell number "reduced cell count of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; these give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Smim3tm1Anjm/Smim3+,Cd74tm1Anjm/Cd74+,Lmo2tm2(cre)Thr/Lmo2+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Bcl11atm2.1Peli/Bcl11atm2.1Peli,Trp53tm1Brn/Trp53tm1Brn,Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv

 MP:0004816 abnormal class switch recombination "anomaly in the rearrangement of the heavy chain genes of differentiating B cells such that the initially encoded heavy chain IgM molecule is altered to one encoding IgG, IgA or IgE; normally, this allows the body to produce antibodies with different effector functions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ightm2Cgn/Ightm2Cgn,Igktm1Rsky/Igktm1Rsky,Trp53tm1Tyj/Trp53tm1Tyj,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac

Allelic Composition: Ightm2Cgn/Ightm2Cgn,Igktm1Rsky/Igktm1Rsky,Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac

Allelic Composition: Cd79atm1(cre)Reth/Cd79a+,Huwe1tm1.1Mak/Y,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL

 MP:0004819 decreased skeletal muscle mass "reduction in the physical bulk, or total amount of matter contained within skeletal muscle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Ing2tm1.1Ccha/Ing2tm1.1Ccha,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0004868 endometrial carcinoma "malignant neoplasm arising from the endometrial tissue" [RGD:Rat Genome Database submission]
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Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(Cdh16-cre)91Igr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N * ICR

 MP:0004896 abnormal endometrium morphology "any structural anomaly of the glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy" [MESH:A05.360.319.679.490, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(Cdh16-cre)91Igr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N * ICR

 MP:0004906 enlarged uterus 
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Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * C57BL/6

 MP:0004953 decreased spleen weight "reduction in the average weight of the organ that functions to filter blood and to store red corpuscles and platelets" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004981 decreased neuronal precursor cell number "reduced number of the neuroblast embryonic cells that develop into nerve cells or neurons" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004986 abnormal osteoblast morphology "any structural anomaly of a bone-forming cell, which normally forms an osseous matrix (osteoid) in which it becomes enclosed as an osteocyte" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

 MP:0005014 increased B cell number "greater than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

 MP:0005017 decreased B cell number "fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Atmintm1.2Jhh/Atmintm1.2Jhh,Trp53tm1Brn/Trp53tm1Brn,Cd79atm1(cre)Reth/Cd79a+
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6

 MP:0005095 decreased T cell proliferation "reduced clonal expansion of naive T cells in response to stimuli" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Trp53tm2Xu/Trp53tm2Xu
Genetic Background: involves: 129S6/SvEvTac

 MP:0005134 decreased thyroid-stimulating hormone level "less than expected concentration of the hormone that stimulates the growth and function of the thyroid gland" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Trp53tm1Brn/Trp53tm1Brn,Tg(TPO-cre)1Shk/0
Genetic Background: 129.Cg-Trp53tm1Brn Ptentm2.1Ppp Tg(TPO-cre)1Shk

 MP:0005135 increased thyroid-stimulating hormone level "less than expected concentration of the hormone that stimulates the growth and function of the thyroid gland" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Braftm1Mmcm/Braf+,Tg(TPO-cre/ERT2)1139Tyj/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * C57BL/6NTac

 MP:0005141 liver hyperplasia "increased size of liver due to increased hepatocyte cell number" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33827]
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Allelic Composition: Sh2d1atm1Cpt/Sh2d1atm1Cpt
Genetic Background: involves: 129S4/SvJae

 MP:0005150 cachexia "general weight loss and wasting occurring in the course of chronic disease" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0005152 pancytopenia "reduction in the number of erythrocytes, all types of white blood cells, and platelets in the circulating blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:20450]
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Allelic Composition: Atrtm1Ofc/Atrtm1Ofc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0005165 increased susceptibility to injury "greater than the normal reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+,Ptf1atm1.1(cre)Cvw/Ptf1a+,Tg(tetO-Kras2)12Hev/0,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J * FVB/N

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0005170 cleft lip "defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Apctm2Rak/Apc+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

 MP:0005195 abnormal posterior eye segment morphology "anomalous structure of any of the parts of the eye that lie in back of, or dorsal to, the lens (but not inclusive) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129S2-Trp53tm1Tyj/J

 MP:0005202 lethargy "mild impairment of consciousness resulting in reduced alertness and awareness; ultimately due to generalized brain dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0005205 abnormal eye anterior chamber "anomaly of the space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Rb1tm1Tyj/Rb1tm2Brn,Rbl1tm1Tyj/Rbl1tm1Tyj,Trp53tm1Brn/Trp53tm1Brn,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Rb1tm1Tyj/Rb1tm2Brn,Rbl1tm1Tyj/Rbl1tm1Tyj,Trp53tm1Brn/Trp53tm1Tyj,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

 MP:0005220 abnormal exocrine pancreas morphology "malformation of the acinar gland portion of the pancreas that secretes digestive enzymes " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Mir122tm1.1Kgh/Mir122+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0005238 increased brain size "larger than the normal physical proportions of the brain" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:57958]
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Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S4/SvJae * FVB/N

Allelic Composition: Trp53tm1Elee/Trp53tm1Tyj,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * FVB/N

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

 MP:0005299 abnormal eye posterior chamber "anomaly of the ringlike space, filled with aqueous humor, between the iris/pupil anteriorly and the lens and ciliary body posteriorly" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Rb1tm1Tyj/Rb1tm2Brn,Rbl1tm1Tyj/Rbl1tm1Tyj,Trp53tm1Brn/Trp53tm1Brn,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Rb1tm1Tyj/Rb1tm2Brn,Rbl1tm1Tyj/Rbl1tm1Tyj,Trp53tm1Brn/Trp53tm1Tyj,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

 MP:0005323 dystonia "impairment of muscle tone resulting in prolonged muscle contraction and involuntary movements such as repetitive movements, or twisting or writhing of the limbs" [J:84533]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0005324 ascites "accumulation or retention of fluid within the peritoneal cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Dicer1tm1Tara/Dicer1tm1Tara,Ptentm1Hwu/Ptentm1Hwu,Trp53tm2Tyj/Trp53+,Amhr2tm3(cre)Bhr/Amhr2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd

Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Trp53tm2Tyj/Trp53+,Amhr2tm3(cre)Bhr/Amhr2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd

 MP:0005355 enlarged thyroid gland "increased size of the endocrine gland located in the front and to the sides of the upper part of the trachea, and which secretes thyroid hormone and calcitonin " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:85158, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Trp53tm1Brn/Trp53tm1Brn,Tg(TPO-cre)1Shk/0
Genetic Background: 129.Cg-Trp53tm1Brn Ptentm2.1Ppp Tg(TPO-cre)1Shk

 MP:0005409 darkened coat color "amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is decreasesd when compared to wild-type agouti" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm2Brd/Trp53tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0005435 hemoperitoneum "blood in the peritoneal cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:87293]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

 MP:0005481 chronic myelocytic leukemia "a heterogeneous group of myeloproliferative disorders that may evolve into acute leukemia in late stages " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0005488 bronchial epithelial hyperplasia "increased numbers of cells lining the inner surfaces of the bronchi" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Rb1tm1Tyj/Rb1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0005498 hyporesponsive to tactile stimuli "reduced reflex action normally induced by touch or pain" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Rb1tm1Tyj/Rb1tm1Tyj,Tg(Rb1)1Blg/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

 MP:0005501 abnormal skin physiology "atypical function of the membranous protective covering of the body" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6

Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Sirt6tm2.2Cxd/Sirt6tm2.2Cxd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * FVB/N * NIH Black Swiss

 MP:0005599 increased cardiac muscle contractility "greater than the normal ability of the heart muscle to shorten or to develop increased tension " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
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Allelic Composition: Odf1tm1Shf/Odf1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0005601 increased angiogenesis "enhanced process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network" [RGD:Rat Genome Database submission]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Pot1atm1Schg/Pot1atm1.1Schg,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Brn/Trp53tm2Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Trp53tm2Tyj/Trp53tm2Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Trp53tm3.1Holl/Trp53tm3.1Holl
Genetic Background: Not Specified

Allelic Composition: Trp53tm1Thst/Trp53tm1Thst
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Trp53tm1.1Thst/Trp53tm1.1Thst
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Gnl3tm2.1Rylt/Gnl3tm2.1Rylt,Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6 * CBA

 MP:0006036 abnormal mitochondrial physiology 
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NCrj

 MP:0006042 increased apoptosis "greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Chek1tm1Sje/Chek1tm1Sje,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Ing2tm1.1Ccha/Ing2tm1.1Ccha,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129/Sv * 129S7/SvEvBrd * C57BL/6J * FVB/N

Allelic Composition: Csnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn,Tg(Vil-cre/ERT2)23Syr/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * C57BL/6 * CD-1 * DBA/2

Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0006043 decreased apoptosis "less than normal cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm3Wahl/Trp53tm3Wahl
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm4Xu/Trp53tm4Xu
Genetic Background: Not Specified

Allelic Composition: Trp53tm5Xu/Trp53tm5Xu
Genetic Background: Not Specified

Allelic Composition: Rb1tm1.1Jyjw/Rb1tm1.1Jyjw,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

Allelic Composition: Trp53tm1Att/Trp53tm1Att,Gt(ROSA)26Sortm1(cre/ERT2)Tyj/?
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm4Att/Trp53tm4Att,Gt(ROSA)26Sortm1(cre/ERT2)Tyj/?
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Dcctm1Nki/Dcctm1Nki,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0006050 pulmonary fibrosis "formation of fibrous tissue within the lung often resulting from inflammation or injury " [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

 MP:0006072 abnormal retinal apoptosis "increase or decrease in the number of cells in the retina undergoing programmed cell death" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92622:]
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Allelic Composition: Rb1tm1Tyj/Rb1tm1Tyj,Tg(Rb1)1Blg/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

 MP:0006099 thin granule layer "reduced thickness of the innermost cortical layer of the cerebellum that contains granule cells" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65410]
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Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0006126 abnormal outflow tract development "anomaly in the development of the common arterial trunk that forms the aorta and pulmonary artery" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0006206 embryonic lethality before turning of embryo "death anytime after somite formation but before embryo turning (E8 to less than E9)" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Hcktm1Hev/Hcktm1Hev,Srctm1Sor/Srctm1Sor
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0006219 optic nerve degeneration "retrogressive pathologic change of the optic nerve" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129S2-Trp53tm1Tyj/J

 MP:0006221 optic nerve hypoplasia "less than the normal number of fibers in the optic nerve" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129S2-Trp53tm1Tyj/J

 MP:0006279 abnormal limb development "anomaly in the formation of the limbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Nabp2tm1.2Nfel/Nabp2tm1.2Nfel,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N * SJL

 MP:0006283 medulloblastoma "a solid, cancerous tumor originating in the cerebellum of the brain and of primitive neuroectodermal origin " [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Xrcc4tm2.1Fwa/Xrcc4tm2Fwa,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * SJL

Allelic Composition: Lig4tm1Icrf/Lig4tm1Icrf,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas) or (involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ)

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc2tm1Pmc/Xrcc2tm1Pmc
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Cdkn2ctm1Bbd/Cdkn2c+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Cdkn2ctm1Bbd/Cdkn2c+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Cdkn2ctm1Bbd/Cdkn2ctm1Bbd,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Cdkn2ctm1Bbd/Cdkn2ctm1Bbd,Trp53tm1Brn/Trp53tm1Tyj,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Trp53tm1Brn/Trp53tm1Tyj,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: SufuGt(XB699)Byg/Sufu+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Ptch1tm1Mps/Ptch1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brd/Trp53tm1Brd,Tg(Gfap-cre)2Brn/0
Genetic Background: involves: 129 * 129S7/SvEvBrd * FVB/N

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Gfap-cre)2Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Nhej1tm1Fwa/Nhej1tm1Fwa,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129/Sv

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd,Xrcc5tm1Dbr/Xrcc5tm1Dbr
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Xrcc5tm1Dbr/Xrcc5tm1Dbr
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc2tm2Pmc/Xrcc2tm2Pmc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Tyj/Trp53+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Ptch1tm1Mps/Ptch1+,Trp53tm1Tyj/Trp53+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Ptch1tm1Mps/Ptch1+,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129 * C57BL/6 * SJL

Allelic Composition: Lig4tm1Pmc/Lig4tm1Pmc,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Lig4tm1Pmc/Lig4tm1Pmc,Trp53tm1Tyj/Trp53tm1Tyj,Xrcc2tm2Pmc/Xrcc2tm2Pmc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Lig4tm1Pmc/Lig4tm1Pmc,Trp53tm1Tyj/Trp53+,Xrcc2tm2Pmc/Xrcc2tm2Pmc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S4/SvJae * FVB/N

Allelic Composition: Trp53tm1Elee/Trp53tm1Tyj,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * FVB/N

Allelic Composition: Xrcc1tm1Pmc/Xrcc1tm1Pmc,Trp53tm1Tyj/Trp53+,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Xrcc1tm1Pmc/Xrcc1tm1Pmc,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Ptch1tm1Cklr/Ptch1+,Trp53tm1Brn/?,Pax7tm1(cre)Mrc/Pax7+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

Allelic Composition: Tg(Atoh1-sb11)1Mtay/0,TgTn(sb-T2/Onc3)12740Njen/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C3H * C57BL/6J * ICR

Allelic Composition: Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+,Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Gfap-cre)2Brn/0
Genetic Background: either: (involves: 129 * 129P2/OlaHsd * FVB/N) or (involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB/N)

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Gfap-cre)2Brn/0
Genetic Background: involves: 129 * 129P2/OlaHsd * FVB/N

Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Pik3catm1Gilb/Pik3ca+,Trp53tm1Brn/Trp53+,Tg(Fabp7-cre,-lacZ)3Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Trp53tm1Brn/Trp53+,Tg(Fabp7-cre,-lacZ)3Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Rtel1tm2.1Hdin/Rtel1tm2.1Hdin,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

Allelic Composition: Tg(Mdm2)1Snj/0,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0006301 abnormal mesenchyme morphology "abnormality in the loosely packed, unspecialized cells that derive mostly from the mesoderm and contribute to connective tissue, bone, cartilage and circulatory and lymphatic systems." [J:120305, mnk:Michelle Knowlton_MGI Curator]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

 MP:0006310 retinoblastoma "a malignant tumor of the retina composed of cells arising from the retinoblasts" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Rb1tm1Tyj/Rb1tm2Brn,Rbl1tm1Tyj/Rbl1tm1Tyj,Trp53tm1Brn/Trp53tm1Brn,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Rb1tm1Tyj/Rb1tm2Brn,Rbl1tm1Tyj/Rbl1tm1Tyj,Trp53tm1Brn/Trp53tm1Tyj,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Rb1tm1Tyj/Rb1tm2Brn,Rbl1tm1Tyj/Rbl1+,Trp53tm1Brn/Trp53tm1Brn,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0006410 abnormal common myeloid progenitor cell morphology "anomaly in the structure of the hematopoietic stem cells that are capable of forming any of the myeloid lineage cells (erythrocytes, granulocytes, thrombocytes, monocytes, and mast cells) but not cells of the lymphoid lineage" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

 MP:0006414 decreased T cell apoptosis "decrease in the number of T cells undergoing programmed cell death" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Trp53tm2Xu/Trp53tm2Xu
Genetic Background: involves: 129S6/SvEvTac

 MP:0008000 ovary tumor "presence of abnormal rapidly proliferating cells in the ovary, usually in the form of a distinct mass" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Stk11tm1Mmt/Stk11+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

Allelic Composition: Tg(Krt18-EGFP,-TAg121)36Ysng/0,Trp53tm1Brn/Trp53tm2Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N

Allelic Composition: Tg(Krt18-EGFP,-TAg121)36Ysng/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N

Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Tg(Krt18-EGFP,-TAg121)36Ysng/0,Trp53tm1Brn/Trp53tm2Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Tg(Krt18-EGFP,-TAg121)36Ysng/0,Trp53tm1Brn/Trp53tm2Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N

Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Tg(Krt18-EGFP,-TAg121)36Ysng/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N

Allelic Composition: KitW-v/KitW-v,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N

Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,KitW-v/KitW-v,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0008008 early cellular replicative senescence "increase in the progression of the process in which a cell progresses from its inception to the end of its lifespan, which occurs as the cell continues cycles of growth and division" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm2Att/Trp53tm2Att
Genetic Background: either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C57BL/6)

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: either: (involves: 129S2/SvPas * C57BL/6 * FVB/N) or (involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6)

Allelic Composition: Trp53tm2Tyj/Trp53tm2Tyj
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm3Tyj/Trp53tm3Tyj
Genetic Background: involves: 129S4/SvJae

 MP:0008009 delayed cellular replicative senescence "slower progression of the process in which a cell progresses from its inception to the end of its lifespan, which occurs as the cell continues cycles of growth and division" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm2.1Snj/Trp53tm2.1Snj
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1.1Dgk
Genetic Background: involves: 129S * 129X1/SvJ * C57BL/6

Allelic Composition: Trp53tm2.1Wgu/Trp53tm2.1Wgu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0008010 gastric adenocarcinoma "malignant neoplasm of epithelial cells in the stomach" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Cdh1tm2Kem/Cdh1+,Smad4tm2.1Cxd/Smad4tm2.1Cxd,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

Allelic Composition: Cdh1tm2Kem/Cdh1tm2Kem,Smad4tm2.1Cxd/Smad4tm2.1Cxd,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

 MP:0008011 intestinal polyps "abnormal tissue masses that protrude into the lumen of the intestine and are tethered to the wall of the intestine" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0008014 lung tumor "presence of abnormal, rapidly proliferating cells on the lung usually in the form of a distinct mass" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Braftm1Mmcm/Braf+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm2Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm3Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Rbl2tm2Tyj/Rbl2tm2Tyj,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)105Ayn/0
Genetic Background: FVB.Cg-Trp53tm1Brn Tg(MMTV-cre)105Ayn

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)105Ayn/0
Genetic Background: FVB.Cg-Trp53tm1Brn Rb1tm2Brn Tg(MMTV-cre)105Ayn

Allelic Composition: Krastm4Tyj/Kras+,Map2k7tm1.1Twad/Map2k7tm1.2Twad,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N

Allelic Composition: Col1a1tm4(CAG-FGFR2_iIIIb*K660N)Kkw/Col1a1+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6

Allelic Composition: Col1a1tm5(CAG-FGFR2_iIIIb*W290C)Kkw/Col1a1+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

Allelic Composition: Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-Kras2)12Hev/0,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

 MP:0008019 liver tumor "presence of abnormal, rapidly proliferating cells in the liver usually in the form of a distinct mass" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Stk11tm1Mmt/Stk11+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ

Allelic Composition: Trp53tm1.1Xlu/Trp53tm1.1Xlu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * FVB/N

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Brca1tm2Cxd/Brca1tm2Cxd,Pkmtm1.1Mgvh/Pkmtm1.1Mgvh,Tg(MMTV-cre)4Mam/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * 129S7/SvEvBrd * FVB/N

Allelic Composition: Rasal2Gt(463C12)Cmhd/Rasal2Gt(463C12)Cmhd,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S * 129X1/SvJ * C57BL/6 * C57BL/6NCrl

 MP:0008026 abnormal brain white matter morphology "any structural anomaly of the regions of the brain that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1+,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0008040 decreased NK T cell number "reduced number of the distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments" [GO:0001865]
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Allelic Composition: Nhej1tm1.1Ics/Nhej1+
Genetic Background: involves: 129 * C57BL/6

 MP:0008057 abnormal DNA replication "any anomaly in the process whereby new strands of DNA are synthesized" [GO:0006260]
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Allelic Composition: Trp53tm3.1Glo/Trp53tm3.1Glo
Genetic Background: B6.129S7-Trp53tm3.1Glo

Allelic Composition: Atrtm1Ofc/Atrtm1Ofc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

 MP:0008186 increased pro-B cell number "greater number of the progenitor cells of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but are not yet fully committed to the B cell lineage until the expression of PAX5 occurs" [CL:0000826, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1.1Awbr/Trp53tm1.1Awbr
Genetic Background: involves: C57BL/6

 MP:0008203 absent B-1a cells "absence of the B-1 B cell subset bearing the CD5 surface marker" [CL:0000820, PMID:11861604]
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Allelic Composition: Cd79atm1(cre)Reth/Cd79a+,Huwe1tm1.1Mak/Y,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL

 MP:0008209 decreased pre-B cell number "reduced number of the cells in the B lymphocyte lineage that have undergone VDJ rearrangement of the immunoglobulin heavy chain and are in the process of V-J rearrangement of the light chain: these cells express mu heavy chain on the cell surface" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]
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Allelic Composition: Noc2ltm1.1Arte/Noc2ltm1.1Arte,Trp53tm1Brn/Trp53tm1Brn,Tg(CD2-icre)4Kio/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/10 * CBA/Ca

 MP:0008215 decreased immature B cell number "reduced number of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]
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Allelic Composition: Atmintm1.2Jhh/Atmintm1.2Jhh,Trp53tm1Brn/Trp53tm1Brn,Cd79atm1(cre)Reth/Cd79a+
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6

 MP:0008260 abnormal autophagy "abnormal catabolic process involving the degradation of a cell s own components through the lysosomal machinery" [MGI:honda "Hiraoki Onda, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NCrj

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

Allelic Composition: Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129S7/SvEvBrd

 MP:0008402 increased cellular sensitivity to alkylating agents "greater incidence of cell death following exposure to agents that cause DNA damage" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rnaseh2btm1a(EUCOMM)Wtsi/Rnaseh2btm1a(EUCOMM)Wtsi,Trp53tm1Mlh/Trp53tm1Mlh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N

 MP:0008410 increased cellular sensitivity to ultraviolet irradiation "greater incidence of cell death following exposure to ultraviolet irradiation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm2.1Dgj/Trp53tm2.1Dgj
Genetic Background: involves: SKH

Allelic Composition: Tg(TRP53)4Dgj/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * FVB

 MP:0008411 decreased cellular sensitivity to ultraviolet irradiation "reduced incidence of cell death following exposure to ultraviolet irradiation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Xu/Trp53tm1Xu
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm1Adv/Trp53tm1Adv
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Adv/Trp53+
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm2Mok/Trp53+
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: Mdm4Gt(VICTR20)7Lex/Mdm4Gt(VICTR20)7Lex,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129S4/SvJae * FVB/N * SKH1

Allelic Composition: Trp53tm1.1Brn/Trp53tm3Tyj,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB/N * SKH1

Allelic Composition: Trp53tm1.1Brn/Trp53tm1.1Brn,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129P2/OlaHsd * FVB/N * SKH1

Allelic Composition: Trp53tm1.1Brn/Trp53+,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129P2/OlaHsd * FVB/N * SKH1

Allelic Composition: Trp53tm1Att/Trp53tm1Att
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm2Att/Trp53tm2Att
Genetic Background: either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C57BL/6)

Allelic Composition: Trp53tm1.1Dgj/Trp53tm1.1Dgj
Genetic Background: involves: SKH

Allelic Composition: Tg(TRP53*R72P)7Dgj/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * FVB

Allelic Composition: Trp53tm2.1Snj/Trp53tm2.1Snj
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0008470 abnormal spleen B cell follicle morphology "any structural anomaly of the area of the white pulp where the affinity maturation of B cells and the generation of memory B cells and plasma cells occur" [PMID:17495967]
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Allelic Composition: Rbm38tm1.1Xch/Rbm38tm1.1Xch,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

 MP:0008477 decreased spleen red pulp amount "reduction in the quantity of the parenchymatous tissue network of the spleen that consists of loose plates or cords (sinuses) infiltrated with red blood cells where most of the blood filtration occurs and degenerate erythrocytes are removed from the circulation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

 MP:0008495 decreased IgG1 level "less than normal immunoglobulin class G1 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd79atm1(cre)Reth/Cd79a+,Huwe1tm1.1Mak/Y,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL

 MP:0008515 thin retinal outer nuclear layer "reduced thickness of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Atp/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0008553 increased circulating tumor necrosis factor level "greater amount in the blood of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MESH:D12.644.276.374.500.800]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

 MP:0008577 increased circulating interferon-gamma level "increase in the amount in the blood of the major interferon produced by mitogenically or antigenically stimulated lymphocytes that is involved in immunoregulation" [MESH:D12.644.276.374.440.893]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

 MP:0008596 increased circulating interleukin-6 level "increase in the amount in the blood of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts" [MESH:D12.644.276.374.465.506]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

 MP:0008623 increased circulating interleukin-3 level "increase in the amount in the blood of a multilineage cell growth factor secreted by lymphocytes, epithelial cells and astrocytes which stimulates clonal proliferation and differentiation of various types of blood and tissue cells" [MESH:D12.644.276.374.410.240.400]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

 MP:0008626 increased circulating interleukin-5 level "increase in the amount in the blood of a cytokine that promotes differentiation and activation of eosinophils; it also triggers activated B-cells to differentiate into immunoglobulin-secreting cells" [MESH:D12.644.276.374.465.505]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

 MP:0008713 abnormal cytokine level "deviation from the normal levels of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Apctm2Rak/Apc+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

 MP:0008714 lung carcinoma "a malignant neoplasm of the ling, arising from epithelial cells, usually glandular or squamous" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

 MP:0008715 lung small cell carcinoma "an anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm" [MESH:C04.557.465.625.650.240.390]
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Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Rbl2tm2Tyj/Rbl2tm2Tyj,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Lejo/Trp53tm1Lejo
Genetic Background: involves: 129

Allelic Composition: Calcatm1.1(cre/ERT2)Ptch/Calca+,Trp53tm1Brn/Trp53tm1Brn,Rb1tm2Brn/Rb1tm2Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * FVB/N

Allelic Composition: Calcatm1.1(cre/ERT2)Ptch/Calca+,Trp53tm1Brn/Trp53tm1Brn,Rb1tm2Brn/Rb1tm2Brn,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S4/SvJae * BALB/c * FVB/N

Allelic Composition: Rb1tm2Brn/Rb1+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

 MP:0008716 lung non-small cell carcinoma "a heterogeneous aggregate of at least three distinct histological types of lung cancer" [MESH:C04.557.470.200.300]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Lejo/Trp53tm1Lejo
Genetic Background: involves: 129S4/SvJae

 MP:0008754 abnormal T cell receptor V(D)J recombination "any anomaly in the process by which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus" [GO:0033153, MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Nhej1tm1.1Ics/Nhej1tm1.1Ics,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0008762 embryonic lethality "death of an animal in the embryonic period (Mus: up to E14)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Atp8a2agil-3J/Atp8a2agil-3J
Genetic Background: CBA/J-Atp8a2agil-3J/GrsrJ

 MP:0008770 decreased survivor rate "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Sirt1tm1.1Cxd/Sirt1tm1.1Cxd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB/N)

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Brca2tm1Kamc/Brca2tm1Kamc,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Rag1tm1Jsek/Rag1tm1Jsek,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0008780 pancreatic acinar cell carcinoma "presence of an adenocarcinoma arising from cells of the pancreas that secrete digestive enzymes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Pdx1-cre/Esr1*)35.10Dam/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA

Allelic Composition: Brca2tm1Brn/Brca2tm1Cam,Krastm4Tyj/Kras+,Trp53tm3Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: ApcMin/Apc+,Trp53tm1Mlh/Trp53tm1Mlh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SWR

 MP:0008813 decreased common myeloid progenitor cell number "reduced number of progenitor cells committed to myeloid lineage, including the megakaryocyte and erythroid lineages" [CL:0000049, MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

 MP:0008844 decreased subcutaneous adipose tissue amount "reduction in amount of adipose tissue beneath the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0008866 chromosomal instability "abnormalities of DNA metabolism, DNA repair, cell-cycle governance, or control of apoptosis that increase the probability that whole chromosomes or pieces of chromosomes are gained or lost during cell division, resulting in an imbalance in the number of chromosomes per cell (aneuploidy) and an enhanced rate of loss of heterozygosity" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:12446840]
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Allelic Composition: Brca1tm2Mak/Brca1tm2Mak,Tg(Lck-cre)548Jxm/?,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA

Allelic Composition: Trp53tm7.1Xu/Trp53tm7.1Xu
Genetic Background: Not Specified

Allelic Composition: Trp53tm7.1Xu/Trp53+
Genetic Background: Not Specified

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)105Ayn/0
Genetic Background: FVB.Cg-Trp53tm1Brn Rb1tm2Brn Tg(MMTV-cre)105Ayn

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Rnaseh2btm1a(EUCOMM)Wtsi/Rnaseh2btm1a(EUCOMM)Wtsi,Trp53tm1Mlh/Trp53tm1Mlh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N

Allelic Composition: Exo1tm2Wed/Exo1tm2Wed,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Rps27lGt(IST11658B7)Tigm/Rps27lGt(IST11658B7)Tigm,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6N

 MP:0008872 abnormal response to xenobiotics "any anomaly in the physiological or morphological changes induced by a foreign compound, such as changes in blood pressure, changes in hormone or protein levels or hypertrophy or hypotrophy of an organ" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008873 increased sensitivity to xenobiotics "decrease in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0008883 abnormal enterocyte proliferation "anomaly in the ability of the enterocyte cell population to undergo expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Csnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn,Tg(Vil-cre/ERT2)23Syr/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * C57BL/6 * CD-1 * DBA/2

 MP:0008884 abnormal enterocyte apoptosis "change in the timing or the number of enterocytes undergoing programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Mlh/Trp53tm1Mlh
Genetic Background: involves: 129P2/OlaHsd

 MP:0008885 increased enterocyte apoptosis "increase in the timing or the number of B cells undergoing programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Brd/Trp53tm8Xu
Genetic Background: involves: 129S7/SvEvBrd

 MP:0008924 decreased granule neuron number "reduction in the number of the small neurons of the granule cell layer that send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition"]
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Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm2Glo/Trp53tm2Glo
Genetic Background: involves: 129S7/SvEvBrd

 MP:0008943 increased sensitivity to induced cell death "decrease in the exposure level to an agent that is required to induce cessation of function at the cellular level" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: C57BL/6 * CBA

 MP:0008944 decreased sensitivity to induced cell death "increase in the exposure level to an agent that is required to induce cessation of function at the cellular level" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1.1Awbr/Trp53tm1.1Awbr
Genetic Background: involves: C57BL/6

 MP:0008973 decreased erythroid progenitor cell number "reduced numbers of progenitors of the erythrocyte lineage" [CL:0000038, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

Allelic Composition: Smim3tm1Anjm/Smim3+,Cd74tm1Anjm/Cd74+,Lmo2tm2(cre)Thr/Lmo2+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

 MP:0008974 proportional dwarf "abnormally undersized with both limbs and trunk symmetrically shorter; usually due to chemical, endocrine, nutritional or nonosseous influences" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Atrtm1Ofc/Atrtm1Ofc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

 MP:0009004 progressive hair loss "thinning of hair (coat) over time, usually in a defined pattern, until entirely gone with no recurrent growth" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR

 MP:0009092 endometrium hyperplasia "overdevelopment or increased size, usually due an increased number of cells, of the glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * C57BL/6

 MP:0009151 pancreatic ductal adenocarcinoma "adenocarcinoma that arises from the pancraetic ducts" [MESH:C04.557.470.200.025.232.750]
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Tg(Pdx1-cre/Esr1*)35.10Dam/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA

Allelic Composition: Brca2tm1Brn/Brca2tm1Cam,Krastm4Tyj/Kras+,Trp53tm3Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Trp53tm3Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Brca2tm1Cam/Brca2+,Krastm4Tyj/Kras+,Trp53tm3Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2a+,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2a+,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Krastm1Bbd/Kras+,Trp53tm1Brd/Trp53+,Tg(Cela1-tTA)#Eps/?,Tg(tetO-cre)3Jig/?
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm2Tyj,Ptf1atm1(cre)Hnak/Ptf1a+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+,Ptf1atm1.1(cre)Cvw/Ptf1a+,Tg(tetO-Kras2)12Hev/0,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Trp53tm1Gev/Trp53tm1Gev
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+,Ptf1atm1.1(cre)Cvw/Ptf1a+,Tg(tetO-Kras*G12D)#Rdp/0,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+,Ptf1atm1.1(cre)Cvw/Ptf1a+,Tg(tetO-Kras*G12D)#Rdp/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

 MP:0009152 pancreatic intraepithelial neoplasia "noninvasive pancreatic duct lesions that affect smaller caliber ducts and do not involve the main pancreatic duct" [PMID:11342768]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+,Ptf1atm1.1(cre)Cvw/Ptf1a+,Tg(tetO-Kras2)12Hev/0,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J * FVB/N

 MP:0009153 pancreas tumor "tumors or cancer of the pancreas" [MESH:C04.588.274.761]
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2a+,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2a+,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Tg(Pdx1-cre)89.1Dam/0
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N

Allelic Composition: Apctm2Rak/Apc+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

 MP:0009219 prostate intraepithelial neoplasia "noninvasive prostate duct lesions that affect smaller caliber ducts" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Brn/Trp53+,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Terttm1Rdp/Terttm1Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Terttm1Rdp/Tert+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Terttm3Rdp/Terttm3Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

 MP:0009220 prostate adenocarcinoma "malignant neoplasm arising from prostate tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Terttm1Rdp/Tert+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Smad4tm1Rdp/Smad4tm1Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129 * C57BL/6 * DBA/2

Allelic Composition: Ptentm1Rdp/Ptentm1Rdp,Terttm3Rdp/Terttm3Rdp,Trp53tm1Brn/Trp53tm1Brn,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2

 MP:0009258 abnormal thymocyte apoptosis "change in the timing or the number of immature T cells located in the thymus that are undergoing programmed cell death" [CL:0000893]
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Allelic Composition: Trp53tm1Xu/Trp53tm1Xu
Genetic Background: involves: 129S4/SvJae

 MP:0009277 brain tumor "presence of abnormal rapidly proliferating cells in the brain, usually in the form of a distinct mass" [MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53Bbl/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53Bbl/Anu

Allelic Composition: Trp53bhy/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53bhy/Anu

Allelic Composition: Nf1tm1Par/Nf1+,Trp53tm1Tyj/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Ptentm1Hwu/Pten+,Trp53tm1Tyj/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Trp53tm1Elee/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Ptentm1Hwu/Pten+,Trp53tm1Elee/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (C3H/HeJ x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (CAST/EiJ x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (CBA/J x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (SJL/J x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Brd/Trp53+
Genetic Background: B6.129-Trp53tm1Brd Nf1tm1Fcr

Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0009278 abnormal bone marrow cell physiology "any functional anomaly of any of the cells found in the blood" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Espl1Gt(XL058)Byg/Espl1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg

 MP:0009308 adenocarcinoma "malignant neoplasm of epithelial cells in a glandular or glandular-like pattern" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm2Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Mdm2tm4.1Glo/Mdm2tm4.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm4.1Glo Trp53tm3.1Glo

Allelic Composition: Trp53tm1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm4Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm3.1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Scgb1a1tm1(cre/ERT)Blh/Scgb1a1+,Trp53tm5Tyj/Trp53+
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Sftpctm1(cre/ERT2)Blh/Sftpc+,Trp53tm5Tyj/Trp53+
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6

 MP:0009309 small intestine adenocarcinoma "malignant neoplasm of epithelial cells in the small intestine" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0009311 duodenum adenocarcinoma "malignant neoplasm of epithelial cells in the duodenum" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Cdh1tm2Kem/Cdh1+,Smad4tm2.1Cxd/Smad4tm2.1Cxd,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

 MP:0009314 colon adenocarcinoma "malignant neoplasm of epithelial cells in the colon" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: H2afxtm1Fwa/H2afxtm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

 MP:0009317 follicular lymphoma "malignant lymphoma arising from lymphoid follicular B cells which may be small or large" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Trp53tm1.1Awbr/Trp53tm1.1Awbr
Genetic Background: involves: C57BL/6

 MP:0009318 splenic marginal zone lymphoma "neoplasm arising from the B cell-rich zones of the spleen" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Trp53tm1Yjc/Trp53tm1Yjc
Genetic Background: B6.129S1-Trp53tm1Yjc

 MP:0009321 histiocytic sarcoma 
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Mdm2tm4.1Glo/Mdm2tm4.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm4.1Glo Trp53tm3.1Glo

Allelic Composition: Trp53tm1.1Awbr/Trp53tm1.1Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Nf1tm1Tyj/Nf1+,Suz12Gt(Betageo)1Khe/Suz12+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0009332 abnormal splenocyte morphology "any structural anomaly of a cell of the spleen" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Espl1Gt(XL058)Byg/Espl1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg

 MP:0009336 increased splenocyte proliferation "increase in the expansion rate of a splenocyte cell population by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Espl1Gt(XL058)Byg/Espl1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg

 MP:0009341 decreased splenocyte apoptosis "reduction in the number of spleen cells undergoing programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Trp53tm1Yjc/Trp53tm1Yjc
Genetic Background: B6.129S1-Trp53tm1Yjc

 MP:0009442 ovarian teratoma "a usually benign tumor found in the ovary that is the result of an anomaly of oogenesis and typically contains a diversity of tissues often representing all organ systems e.g. hair, teeth, bone, thyroid, nerve tissue" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Braftm1Mmcm/Braftm1Mmcm,Nkx3-1tm4(cre/ERT2)Mms/Nkx3-1+,Ptentm1Hwu/Pten+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6

 MP:0009504 abnormal mammary gland epithelium morphology "any structural anomaly of the epithelial layer of the luminal surfaces of the mammary gland" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tg(MMTV-AURKA)#Cxd/?,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0009506 abnormal mammary gland alveolus morphology "any structural anomaly of the sac-like structure of the mammary gland that secretes milk after pregnancy" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Chek1tm2.1Sje/Chek1+,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Chek1tm2.1Sje/Chek1tm2.1Sje,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Chek1tm2.1Sje/Chek1tm2.1Sje,Trp53tm1Brn/Trp53+,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Chek1tm2.1Sje/Chek1+,Trp53tm1Brn/Trp53+,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

 MP:0009508 mammary gland ductal carcinoma "higher than normal incidence of malignant tumors of the ducts of the mammary gland" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Brca1tm1Aash/Brca1tm1Aash,Trp53tm1Brd/Trp53+,Tg(LGB-cre)74Acl/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * CBA

 MP:0009541 increased thymocyte apoptosis "increase in the number of immature T cells located in the thymus that are undergoing programmed cell death" [CL:0000893, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm3.1Holl/Trp53tm3.1Holl
Genetic Background: Not Specified

Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

 MP:0009542 decreased thymocyte apoptosis "reduction in the number of immature T cells located in the thymus that are undergoing programmed cell death" [CL:0000893, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Trp73tm2Mak/Trp73tm2Mak
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Trp53tm7.1Xu/Trp53tm7.1Xu
Genetic Background: Not Specified

Allelic Composition: Trp53tm1Holl/Trp53tm7.1Xu
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Trp53tm1.1Awbr/Trp53tm1.1Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1Glo/Trp53tm1Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.1Wgu/Trp53tm1.1Wgu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Trp53tm2.1Wgu/Trp53tm2.1Wgu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Nhej1tm1.1Ics/Nhej1tm1.1Ics,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Thst/Trp53tm1Thst
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Trp53tm1.1Thst/Trp53tm1.1Thst
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

Allelic Composition: Tg(Trp53)1Srn/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

 MP:0009550 urinary bladder carcinoma "a malignant neoplasm of the urinary bladder, arising from epithelial cells" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB

 MP:0009551 urinary bladder transitional cell carcinoma "a malignant neoplasm of the transitional epithelial layer of the urinary bladder" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

 MP:0009552 urinary bladder obstruction "any impediment or blockage of the musculomembranous elastic bag serving as a storage place for urine" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Trp53tm1Thl/Trp53tm1Thl,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * DBA/2

 MP:0009566 meiotic nondisjunction "failure of homologous chromosomes to separate to the cell poles at anaphase" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0009583 increased keratinocyte proliferation "increase in the expansion rate of keratinocytes by cell division" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Tg(KRT14-cre)8Brn/0,Tg(KRT5-Akt1*)Jmpa/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * DBA/2J * FVB/N

 MP:0009591 liver adenocarcinoma "malignant neoplasm of epithelial cells in the liver" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Mdm2tm4.1Glo/Mdm2tm4.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm4.1Glo Trp53tm3.1Glo

 MP:0009600 hypergranulosis "increased thickness of the granular layer of the epidermis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR

 MP:0009625 abnormal abdominal lymph node morphology 
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Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0009704 skin squamous cell carcinoma "a skin carcinoma derived from stratified squamous epithelium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trim71Gt(XD089)Byg/Trim71Gt(XD089)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre/ERT)20Efu/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * CD-1

Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N * FVB/N * ICR

 MP:0009764 decreased sensitivity to induced morbidity/mortality "increase in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0009766 increased sensitivity to xenobiotic induced morbidity/mortality "decrease in the amount of a foreign compound required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Ldo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

 MP:0009781 abnormal preimplantation embryo development "an anomaly in the developmental progress of an embryo from 2 cell to blastocyst affecting the viability or number of embryos" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Emg1tm1Hdin/Emg1tm1Hdin,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S * 129S2/SvPas * 129X1/SvJ * CD-1 * ICR

 MP:0009808 reduced oligodendrocyte number "significantly fewer than the expected number of cells of the central nervous system that form the insulating myelin sheath of axons in the CNS are present" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0009828 delayed tumor appearance "later onset of tumor occurence than expected, but with expected incidence" [MGI:mberry "Melissa Berry, Genetics Resources Curator"]
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Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(MMTV-cre)AElee/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm2Xu/Trp53tm2Xu
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Trp53tm3Wahl/Trp53tm3Wahl
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Rpl27aSfa/Rpl27a+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N

Allelic Composition: Brca1tm2.1Cxd/Brca1tm3.1Thl,Trp53tm3Tyj/Trp53+,Waptm1(cre)Arge/Wap+
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129S6/SvEvTac * C57BL/6

 MP:0009908 protruding tongue "the tongue extends out beyond the oral cavity past the lips; may be due to paralysis, oral cavity size, tongue hypoplasia or dysfunction of the hypoglossal nerve" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0009937 abnormal neuron differentiation "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Cdkn2ctm1Bbd/Cdkn2ctm1Bbd,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Xrcc1tm1Pmc/Xrcc1tm1Pmc,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

 MP:0009956 abnormal cerebellar layer morphology "any structural anomaly of the laminar structure of the cerebellar cortex comprising the gray matter of the cerebellum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0009967 abnormal neuron proliferation "any anomaly in the ability of a neuron to undergo rapid expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Atrtm2Bal/Atrtm2Bal,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0009977 abnormal cerebellar granule cell migration "defective or impaired movement of cerebellar granule cell neurons from the germinal zone into the granule cell layer of the cerebellum during development of the cerebellar cortex" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

 MP:0010094 abnormal chromosome stability "anomaly in the probability that whole chromosomes or pieces of chromosomes are gained or lost during cell division, resulting in an imbalance in the number of chromosomes per cell (aneuploidy) and an reduced rate of loss of heterozygosity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Exo1tm3.1Wed/Exo1tm3.1Wed,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010144 abnormal tumor vascularization "aberrant process of blood vessel formation and the subsequent remodeling process within and/or around tumors" [MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"]
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Allelic Composition: Cdh1tm1Jjon/Cdh1tm1Jjon,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Cdh1tm1Jjon/Cdh1tm1Jjon,Trp53tm1Brn/Trp53+,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Chek1tm2.1Sje/Chek1+,Trp53tm1Brn/Trp53+,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

 MP:0010173 increased mammary gland epithelium proliferation "increase in the expansion rate of the cells of the mammary gland epithelium by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Brca1tm2Cxd/Brca1tm2Cxd,Tg(MMTV-cre)4Mam/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB

 MP:0010207 abnormal telomere morphology "any structural anomaly of the terminal repetitive DNA section of a chromosome which is involved in chromosomal replication and senescence, and which protects the end of the chromosome from deterioration" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rtel1tm2.1Hdin/Rtel1tm2.1Hdin,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0010268 decreased lymphoma incidence "less than the expected number of neoplasms derived from lymphoid tissue in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tg(TRP53)4Dgj/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * FVB

Allelic Composition: Tg(TRP53*R72P)7Dgj/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * FVB

Allelic Composition: Rpl27aSfa/Rpl27a+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+,Tacc3tm1.1Tno/Tacc3tm1.2Tno,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Ino80tm1.1Schg/Ino80+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0010269 decreased mammary gland tumor incidence "less than the expected number of neoplasms in the mammary gland, usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Brca1tm1Brn/Brca1tm1.1Jjon,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N

 MP:0010273 increased classified tumor incidence "greater than the expected number of tumors with a specific classification type in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dcctm1Nki/Dcctm1Nki,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0010274 increased organ/body region tumor incidence "greater than the expected number of tumors originating in a specific body region or organ in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm4Att/Trp53tm4Att,Gt(ROSA)26Sortm1(cre/ERT2)Tyj/?
Genetic Background: involves: 129S4/SvJae

 MP:0010275 increased melanoma incidence "greater than the expected number of malignant neoplasms, derived from melanocytes and occuring in pigmented tissues, in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB

Allelic Composition: Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh,Trp53tm1Brn/Trp53tm1Brn,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Cdkn2atm2.1Nesh/Cdkn2a+,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB

 MP:0010277 increased astrocytoma incidence "greater than the expected number of tumors that arise from astrocytes, large neuroglia cells of nervous tissue, occurring in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Nf1tm1Tyj/?,Trp53tm1Tyj/?,Mastr129S4/SvJae/?
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6J

Allelic Composition: Ptentm1Rdp/Pten+,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Trp53tm1Tyj/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Ptentm1Hwu/Pten+,Trp53tm1Tyj/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Trp53tm1Elee/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Par/Nf1+,Ptentm1Hwu/Pten+,Trp53tm1Elee/Trp53+,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * FVB/N

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (C3H/HeJ x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (CAST/EiJ x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (SJL/J x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sortm1Sor,Ptentm1Mro/Ptentm1Mro,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB

Allelic Composition: Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sortm1Sor,Ptentm1Mro/Ptentm1Mro,Slc1a3tm1(cre/ERT2)Mgoe/Slc1a3+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJaeSor

 MP:0010278 increased glioma incidence "greater than the expected number of tumors that arise from glial cells, non-neuronal cells of the nervous tissue, occurring in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tg(S100b-v-erbB)4496Waw/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * DBA/2J * FVB/N

Allelic Composition: Ptentm1Rdp/Pten+,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N

Allelic Composition: Tg(NES-TVA)J12Ech/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129 * C57BL/6 * FVB/N

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S4/SvJae * FVB/N

Allelic Composition: Trp53tm1Elee/Trp53tm1Tyj,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * FVB/N

Allelic Composition: Nf1tm1Fcr/Nf1tm1Fcr,Trp53tm1Elee/Trp53tm1Elee,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * FVB/N

Allelic Composition: Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sortm1Sor,Ptentm1Mro/Ptentm1Mro,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Nf1tm1Tyj/Nf1+,Suz12Gt(Betageo)1Khe/Suz12+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Tg(S100b-v-erbB)4496Waw/0,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * DBA/2J

Allelic Composition: Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sortm1Sor,Ptentm1Mro/Ptentm1Mro,Slc1a3tm1(cre/ERT2)Mgoe/Slc1a3+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJaeSor

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0010279 increased gastrointestinal tumor incidence "greater than the expected number of tumors originating in the gastrointestinal system in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Krt19tm1(cre/ERT)Ggu/Krt19+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac

 MP:0010280 increased skeletal tumor incidence "greater than the expected number of neoplasms in the skeletal tissue, usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

 MP:0010281 increased nervous system tumor incidence "greater than the expected number of tumors originating in the nervous system in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Ptgdstm1.1(cre)Gvn/Ptgds+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sortm1Sor,Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N

Allelic Composition: Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sortm1Sor,Ptentm1Mro/Ptentm1Mro,Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N

 MP:0010285 decreased skin tumor incidence "less than the expected number of neoplasms in the skin tissue usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Brca1tm1Brn/Brca1tm1.1Jjon,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N

 MP:0010287 increased reproductive system tumor incidence "greater than the expected number of tumors originating in the reproductive system in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

 MP:0010289 increased urinary system tumor incidence "greater than the expected number of tumors originating in the urinary system in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Trp53tm1Tyj/Trp53+,Xpatm1Hvs/Xpatm1Hvs
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0010299 increased mammary gland tumor incidence "greater than the expected number of neoplasms in the mammary gland, usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Brca1tm1Cxd/Brca1tm2Cxd,Trp53tm1Brd/Trp53+,Tg(MMTV-cre)4Mam/0
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(MMTV-cre)AElee/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Brca1tm1Aash/Brca1tm1Aash,Trp53tm1Brd/Trp53+,Tg(LGB-cre)74Acl/0
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Suprmam1BALB/cMed/Suprmam1BALB/cMed,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * BALB/cMed * C57BL/6 * C57BL/6J

Allelic Composition: Brca1tm1Brn/Brca1+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N

Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53+,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N

Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N

Allelic Composition: Brca2tm1Kamc/Brca2tm1Kamc,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Brca2tm1Brn/Brca2+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Brn/Trp53+,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Rev3ltm1Rwd/Rev3ltm2.1Rwd,Trp53tm1Brd/Trp53+,Tg(MMTV-cre)1Mam/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Chek1tm2.1Sje/Chek1+,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Chek1tm2.1Sje/Chek1tm2.1Sje,Trp53tm1Brn/Trp53+,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Chek1tm2.1Sje/Chek1+,Trp53tm1Brn/Trp53+,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)105Ayn/0
Genetic Background: FVB.Cg-Trp53tm1Brn Tg(MMTV-cre)105Ayn

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)105Ayn/0
Genetic Background: FVB.Cg-Trp53tm1Brn Rb1tm2Brn Tg(MMTV-cre)105Ayn

Allelic Composition: Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

Allelic Composition: Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+,Tg(MMTV-cre)#Tfln/0,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

Allelic Composition: Trp53tm1Brn/Trp53+,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Brca1tm2Cxd/Brca1tm2Cxd,Tg(MMTV-cre)4Mam/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB

Allelic Composition: Brca1tm2Cxd/Brca1tm2Cxd,Tg(MMTV-cre)4Mam/0,Tg(MMTV-rtTA)1Lach/0,Tg(tetO-Esr1)#Paf/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB

Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N

Allelic Composition: Palb2tm1.1Dli/Palb2tm1.1Dli,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)1Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CBA

Allelic Composition: Palb2tm1.1Dli/Palb2tm1.1Dli,Trp53tm1Brn/Trp53+,Tg(KRT14-cre)1Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CBA

Allelic Composition: Brca1tm2Cxd/Brca1tm2Cxd,Pkmtm1.1Mgvh/Pkmtm1.1Mgvh,Tg(MMTV-cre)4Mam/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * 129S7/SvEvBrd * FVB/N

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0010300 increased skin tumor incidence "greater than the expected number of neoplasms in the skin tissue usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Adv/Trp53tm1Adv
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Adv/Trp53+
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc2tm1Pmc/Xrcc2tm1Pmc
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Cdh1tm1Jjon/Cdh1tm1Jjon,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Cdh1tm1Jjon/Cdh1tm1Jjon,Trp53tm1Brn/Trp53+,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Cdh1tm1Jjon/Cdh1+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129S4/SvJae * FVB/N * SKH1

Allelic Composition: Trp53tm1.1Brn/Trp53tm3Tyj,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB/N * SKH1

Allelic Composition: Trp53tm1.1Brn/Trp53tm1.1Brn,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129P2/OlaHsd * FVB/N * SKH1

Allelic Composition: Trp53tm1.1Brn/Trp53+,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129P2/OlaHsd * FVB/N * SKH1

Allelic Composition: Trp53tm3.1Tyj/Trp53+
Genetic Background: involves: 129S4/SvJae * SKH1

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Brca2tm1Brn/Brca2+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Brca2tm1Brn/Brca2tm1Brn,Trp53tm1Brn/Trp53+,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Krt19tm1(cre/ERT)Ggu/Krt19+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac

Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N

Allelic Composition: Palb2tm1.1Dli/Palb2tm1.1Dli,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)1Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CBA

Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR

Allelic Composition: Dicer1tm1Snj/Dicer1tm1Snj,Trp53tm1Brn/Trp53+,Tg(KRT5-cre/PGR)1Der/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR

 MP:0010301 increased stomach tumor incidence "greater than the expected number of neoplasms in the gastric tissue usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Brca2tm1Kamc/Brca2tm1Kamc,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Rag1tm1Mom/Rag1tm1Mom,Trp53tm1Brd/Trp53tm1Brd,Xrcc5tm1Dbr/Xrcc5tm1Dbr
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Rasal2Gt(463C12)Cmhd/Rasal2Gt(463C12)Cmhd,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S * 129X1/SvJ * C57BL/6 * C57BL/6NCrl

 MP:0010306 increased hamartoma incidence "greater than the expected number of benign focal malformations in a specific population in a given time period; results from faulty development of an organ, and is composed of an abnormal mixture of tissue elements, or an abnormal proportion of a single element normally present at that site" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Stk11tm1.1Mlfr/Stk11+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Stk11tm1.1Mlfr/Stk11+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Stk11tm1Mmt/Stk11+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ

Allelic Composition: Stk11tm1Mmt/Stk11+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

 MP:0010307 abnormal tumor latency "anomaly in the expected time of onset of tumor occurrence" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

Allelic Composition: Dcctm1Nki/Dcctm1Nki,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0010308 decreased tumor latency "earlier onset of tumor occurrence than expected" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Wrntm1Led/Wrntm1Led
Genetic Background: either: (involves: 129S/SvEv) or (involves: 129S/SvEv * NIH Black Swiss)

Allelic Composition: Dph1tm2Bhr/Dph1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Ccne1tm1Jro/?,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: either: (involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6J) or (involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * C57BL/6J)

Allelic Composition: Nbntm1Jpt/Nbntm1Jpt,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Suds3tm1.1Rdp/Suds3+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB

Allelic Composition: Trp53tm1.1Brn/Trp53tm1.1Brn
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * FVB/N

Allelic Composition: Nf1tm1Fcr/Nf1tm1Fcr,Trp53tm1Elee/Trp53tm1Elee,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * FVB/N

Allelic Composition: Brca1tm1Brn/Brca1tm1.1Jjon,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Thl,Trp53tm3Tyj/Trp53+,Waptm1(cre)Arge/Wap+
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129S6/SvEvTac * C57BL/6

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm3Tyj/Trp53+,Waptm1(cre)Arge/Wap+
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129S6/SvEvTac * C57BL/6

Allelic Composition: Brca1tm1Thl/Brca1tm3.1Thl,Krastm4Tyj/Kras+,Trp53tm1Thl/Trp53tm1Thl,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Thl/Trp53tm1Thl,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * FVB/N

Allelic Composition: Brca1tm1Thl/Brca1tm1Thl,Krastm4Tyj/Kras+,Trp53tm1Thl/Trp53tm1Thl,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Brca1tm1Thl/Brca1tm2.1Thl,Krastm4Tyj/Kras+,Trp53tm1Thl/Trp53tm1Thl,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Palb2tm1.1Dli/Palb2tm1.1Dli,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)1Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CBA

Allelic Composition: Palb2tm1.1Dli/Palb2tm1.1Dli,Trp53tm1Brn/Trp53+,Tg(KRT14-cre)1Amc/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CBA

Allelic Composition: Rtel1tm2.1Hdin/Rtel1tm2.1Hdin,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

Allelic Composition: Rbm38tm1.1Xch/Rbm38tm1.1Xch,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

Allelic Composition: Trp53tm1Tyj/Trp53tm1.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm1.1Umol/Trp53tm1.1Umol
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

 MP:0010309 increased mesothelioma incidence "greater than the expected number of neoplasms derived from the lining cells of the pleura and peritoneum, in a specific population in a given time period; is composed of spindle cells or fibrous tissue which may enclose glandlike spaces lined by cuboidal cells" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Cdkn2atm1.1Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tsc1tm1Djk/Tsc1tm1Djk
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

 MP:0010310 increased Schwannoma incidence "greater than the expected number of benign, encapsulated nerve sheath tumors composed of Schwann cells, in a specific population in a given time period; usually associated with a peripheral or cranial nerve" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

 MP:0010312 increased oligodendroglioma incidence "greater than the expected number of encapsulated neoplasms derived from oligodendrocytes, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tg(S100b-v-erbB)4496Waw/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * DBA/2J * FVB/N

Allelic Composition: Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sortm1Sor,Ptentm1Mro/Ptentm1Mro,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB

Allelic Composition: Tg(S100b-v-erbB)4496Waw/0,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * DBA/2J

Allelic Composition: Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sortm1Sor,Ptentm1Mro/Ptentm1Mro,Slc1a3tm1(cre/ERT2)Mgoe/Slc1a3+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJaeSor

 MP:0010313 increased osteoma incidence "greater than the expected number of benign neoplasms derived from lamellar bone, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2+,Trp53tm1Brd/Trp53+,Tg(P0-Cre)3Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

 MP:0010314 increased neurofibroma incidence "greater than the expected number of benign, encapsulated nerve sheath tumors composed of Schwann cells, in a specific population in a given time period; proliferation is disordered and includes portions of nerve fibers" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

 MP:0010315 increased cholangiocarcinoma incidence "greater than the expected number of malignant adenocarcimomas arising in the intrahepatic bile duct epithelium, in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

 MP:0010316 increased thyroid tumor incidence "greater than the expected number of neoplams in the thyroid occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rb1tm1Tyj/Rb1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Calcatm1.1(cre/ERT2)Ptch/Calca+,Trp53tm1Brn/Trp53tm1Brn,Rb1tm2Brn/Rb1tm2Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * FVB/N

Allelic Composition: Calcatm1.1(cre/ERT2)Ptch/Calca+,Trp53tm1Brn/Trp53tm1Brn,Rb1tm2Brn/Rb1tm2Brn,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S4/SvJae * BALB/c * FVB/N

Allelic Composition: Hrastm1Jaf/Hrastm1Jaf,Trp53tm1Brn/Trp53tm1Brn,Tg(TPO-cre)1Shk/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * C57BL/6 * FVB/NCr

 MP:0010320 increased pituitary gland tumor incidence "greater than the expected number of neoplams in the pituitary gland occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Atp/0
Genetic Background: involves: 129S2/SvPas * FVB/N

Allelic Composition: Gt(ROSA)26Sortm1(CAG-Bmi1,-EGFP)Nki/Gt(ROSA)26Sor+,Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Gfap-cre)2Brn/0
Genetic Background: either: (involves: 129 * 129P2/OlaHsd * FVB/N) or (involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB/N)

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Gfap-cre)2Brn/0
Genetic Background: involves: 129 * 129P2/OlaHsd * FVB/N

 MP:0010322 increased cutaneous melanoma incidence "greater than the expected number of a dark-pigmented, usually malignant tumor arising from a melanocyte in the skin, occurring in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tarbp2tm1.2Dzw/Tarbp2tm1.2Dzw
Genetic Background: involves: 129 * FVB/N

 MP:0010334 pleural effusion "accumulation of excess fluid in the pleural cavity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cdkn2atm1.1Brn/Cdkn2a+,Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd

 MP:0010337 increased chronic lymphocytic leukemia incidence 
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Allelic Composition: Ightm2.1(Tag)Rwhe/Igh+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Ightm1.1(Tag)Rwhe/Igh+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0010343 increased lipoma incidence "greater than the expected number of a benign neoplasia derived from lipoblasts or lipocytes of white or brown fat, occurring in a specific population in a given time period" [MPATH:417]
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Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Trp53tm1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0010344 increased hibernoma incidence "greater than the expected number of a benign neoplasm derived from brown fat occurring in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

Allelic Composition: Trp53tm1.2Awbr/Trp53+
Genetic Background: involves: C57BL/6

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1

 MP:0010346 increased thyroid carcinioma incidence "greater than the expected number of a malignant epithelial neoplasms of the thyroid gland, occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Trp53tm1Brn/Trp53tm1Brn,Tg(TPO-cre)1Shk/0
Genetic Background: 129.Cg-Trp53tm1Brn Ptentm2.1Ppp Tg(TPO-cre)1Shk

Allelic Composition: Braftm1Mmcm/Braf+,Trp53tm3.1Tyj/Trp53+,Tg(TPO-cre/ERT2)1139Tyj/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * C57BL/6NTac

Allelic Composition: Braftm1Mmcm/Braf+,Trp53tm1Brn/Trp53tm3.1Tyj,Tg(TPO-cre/ERT2)1139Tyj/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * C57BL/6NTac

Allelic Composition: Braftm1Mmcm/Braf+,Tg(TPO-cre/ERT2)1139Tyj/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * C57BL/6NTac

 MP:0010347 osseous metaplasia "the formation of mature bone elements in the stroma of a neoplasm" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53+,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Trp53tm1Brd/Trp53tm1Brd,Tg(P0-Cre)2Gth/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

 MP:0010348 increased pancreatic islet cell carcinoma incidence "greater than the expected number of malignant neoplasms arising in the pancreatic islet cells, occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rb1tm1Tyj/Rb1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(Ren-cre)#Kwg/0
Genetic Background: involves: 129 * 129P2/OlaHsd

 MP:0010349 increased teratocarcinoma incidence "greater than the expected number of a mixed germ cell neoplasm contaning elements of embryonal carcinoma and teratoma, occurring in a specific population in a given time period" [MPATH:321]
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Allelic Composition: Trp53bhy/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53bhy/Anu

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0010351 increased pituitary melanotroph tumor incidence "greater than the expected number of neoplasms derived from the cells of intermediate pituitary that produce melanocyte stimulating hormone and other peptides from the post-translational processing of pro-opiomelanocortin (POMC)" [CL:0000440, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rb1tm1Tyj/Rb1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010357 increased prostate gland tumor incidence "greater than the expected number of neoplams in the prostate gland occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Trp53tm1Thl/Trp53tm1Thl,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * DBA/2

 MP:0010363 increased fibrosarcoma incidence "greater than the expected number of a highly aggressive malignant neoplasm arising from fibrous connective tissue, in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53Bbl/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53Bbl/Anu

Allelic Composition: Trp53bhy/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53bhy/Anu

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Mdm2tm4.1Glo/Mdm2tm4.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm4.1Glo Trp53tm3.1Glo

Allelic Composition: Trp53tm1.1Awbr/Trp53tm1.1Awbr
Genetic Background: involves: C57BL/6

 MP:0010367 increased spindle cell carcinoma incidence "greater than the expected number of a highly malignant variant of squamous cell carcinoma, occurring in a specific population in a given time period; spindle cell carcinoma shows biphasic proliferation of conventional SCC component and malignant spindle shape cells with sarcomatous appearance" [PMID:19040765]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm3Glo,Tg(KRT5-cre/PGR)1Der/?
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * FVB * ICR

Allelic Composition: Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB

Allelic Composition: Cdkn2atm2.1Nesh/Cdkn2a+,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53+,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Tyr-cre/ERT2)13Bos/0
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB

Allelic Composition: Trp53tm1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm4Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm3.1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Dcctm1Nki/Dcctm1Nki,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0010383 increased adenoma incidence "greater than the expected number of a benign epithelial neoplasm with a glandular organization, occurring in a specific population in a given time period; this tumor type usually does not invade or infiltrate surrounding tissue but may remain a benign tumor or progress to malignancy" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:C04.557.470.035]
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010402 ventricular septal defect "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0010537 tumor regression "a decrease in tumor size from a formerly larger state and/or a decrease in the extent of tumors in the body" [MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"]
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Allelic Composition: Alms1L2131X/Alms1L2131X
Genetic Background: involves: C57BL/6 * NOD

Allelic Composition: Trp53tm1Glo/Trp53tm4Glo,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0010639 altered tumor pathology "any changes associated with the chemistry, immunohistology, cellular alterations or environmental interactions of tumors compared to the expected state" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rb1tm2Brn/Rb1tm2Brn,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Trp53tm1Glo/Trp53tm4Glo,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Trp53tm3.1Glo/Trp53tm4Glo,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Espl1Gt(XL058)Byg/Espl1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg

Allelic Composition: Brca1tm1Brn/Brca1tm1.1Jjon,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N

Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N

Allelic Composition: Braftm1.1Brd/Braf+,Tg(Vil1-cre)997Gum/0,Trp53tm2Tyj/Trp53tm2Tyj
Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * SJL

Allelic Composition: Rb1tm2Brn/Rb1+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd

 MP:0010711 persistent hyperplastic primary vitreous "persistence of the embryonic fibrovascular mesodermal tissue located between the optic cup and lens vesicle that normally regresses during the development of the vitreous body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cdkn2atm1Cjs/Cdkn2atm1Cjs,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0010715 coloboma of the retina "congenital defect of the retina in which some part of the structure is absent" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0010727 increased glioblastoma incidence "greater than the expected number of a fast-growing type of central nervous system tumor that forms from glial tissue of the brain and spinal cord and has cells that look very different from normal cells; glioblastoma usually occurs in adults and affects the brain more often than the spinal cord" [NCI:CDRID45698 "http://www.cancer.gov/dictionary/?CdrID=45698"]
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Allelic Composition: Ptentm1Rdp/Pten+,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N

Allelic Composition: Gt(ROSA)26Sortm2Thl/Gt(ROSA)26Sor+,Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Thl/Trp53tm1Thl,Tyrc-Brd/Tyrc-Brd
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (C3H/HeJ x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (CAST/EiJ x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: (SJL/J x B6.129S2-Trp53tm1Tyj Nf1tm1Tyj/+ +)F1

 MP:0010763 abnormal hematopoietic stem cell physiology "any functional anomaly or number of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; HSCs give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ctla4tm1Shr/Ctla4tm1Shr,Rag2tm1Fwa/Rag2tm1Fwa,Tg(DO11.10)10Dlo/0
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

Allelic Composition: Bcl11atm2.1Peli/Bcl11atm2.1Peli,Trp53tm1Brn/Trp53tm1Brn,Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv

 MP:0010769 abnormal survival "deviation from the expected viability or life span of an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rpl27aSfa/Rpl27a+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

Allelic Composition: Sugt1Gt(RRS405)Byg/Sugt1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Epha2tm1Jrui/Epha2tm1Jrui,Krastm4Tyj/Kras+,Tg(Pdx1-cre)6Tuv/0,Trp53tm2.1Tyj/Trp53+
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * FVB/N

Allelic Composition: Rbm24tm1.1Xch/Rbm24tm1.1Xch,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

 MP:0010810 increased type II pneumocyte number "greater number of the granular and roughly cuboidal cells typically found at the alveolar-septal junction that modulate the fluid surrounding the alveolar epithelium by secreting and recycling surfactants, and also contribute to tissue repair and can differentiate after injury into a type I pneumocyte; type II cells cover a much smaller surface area than type I cells (less than 5 percent), but are much more numerous and contain lamellar bodies on the apical surface where surfactant is stored" [ISBN:0412046911, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", PMID:8540632]
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Allelic Composition: Krastm4Tyj/Kras+,Sftpctm1.1(cre/ERT2)Ptch/Sftpc+,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB

 MP:0010918 abnormal pulmonary neuroendocrine bodies "any structural anomaly of the corpuscular, organoid structures composed of PNECs, found as distinctive innervated clusters only within intrapulmonary airways, where they appear concentrated at airway branch points; NEBs reach from the basement membrane to the airway lumen and are thought to function as oxygen sensors" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Calcatm1.1(cre/ERT2)Ptch/Calca+,Trp53tm1Brn/Trp53tm1Brn,Rb1tm2Brn/Rb1tm2Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * FVB/N

Allelic Composition: Calcatm1.1(cre/ERT2)Ptch/Calca+,Trp53tm1Brn/Trp53tm1Brn,Rb1tm2Brn/Rb1tm2Brn,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S4/SvJae * BALB/c * FVB/N

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Sirt1tm1.1Cxd/Sirt1+
Genetic Background: either: (involves: 129S6/SvEvTac * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * C57BL/6 * FVB/N)

Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Nabp2tm1.2Nfel/Nabp2tm1.2Nfel,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N * SJL

Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Gt(ROSA)26Sortm1(Gck)Ydor/Gt(ROSA)26Sor+,Trp53tm1Brn/Trp53tm1Brn,Tg(Ins2-cre)25Mgn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Dph1tm2Bhr/Dph1+
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Ddb1tm1Spg/Ddb1tm1Spg,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Usp7tm2Wgu/Usp7tm2Wgu,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * SJL

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Lig4tm1Icrf/Lig4tm1Icrf,Trp53tm1Tyj/Trp53+
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas) or (involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ)

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc2tm1Pmc/Xrcc2tm1Pmc
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Sirt1tm1.1Cxd/Sirt1tm1.1Cxd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB/N)

Allelic Composition: Sirt1tm1.1Cxd/Sirt1tm1.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB/N)

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Twsg1tm1.1Mboc/Twsg1tm1.1Mboc
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Hprttm1(ACTB-Epor)Unc/Hprttm1(ACTB-Epor)Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Terf1tm1Tdl/Terf1tm1Tdl,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Mdm2tm1Bay/Mdm2tm1Bay,Trp53tm1Snj/Trp53tm1Snj
Genetic Background: involves: C57BL/6

Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm1Wahl/Trp53tm1Wahl
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm3Wahl/Trp53tm3Wahl
Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd

Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm2Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ

Allelic Composition: Cops6Gt(RRI087)Byg/Cops6Gt(RRI087)Byg,Trp53tm1Glo/Trp53tm1Glo
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Mdm2tm1Bay/Mdm2tm1Bay,Trp53tm2.1Kasa/Trp53tm2.1Kasa
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tsg101tm1Mak/Tsg101tm1Mak
Genetic Background: involves: 129P3/J * 129S2/SvPas * C57BL/6 * CD-1

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc1tm1Rpe/Xrcc1tm1Rpe
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ

Allelic Composition: Ubr5tm1Ckww/Ubr5tm1Ckww,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

Allelic Composition: Npm1tm1Ppp/Npm1tm1Ppp,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Cdca8tm1Tatn/Cdca8tm1Tatn,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Pknox1tm1Fbla/Pknox1tm1Fbla,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm1Glo/Trp53tm1Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Rpl27aSfa/Rpl27aSfa,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Trp53tm3.1Holl/Trp53tm3.1Holl,Xrcc4tm1Fwa/Xrcc4tm1Fwa
Genetic Background: involves: 129P2/OlaHsd

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
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Allelic Composition: Chek1tm1Sje/Chek1tm1Sje,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd

 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
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Allelic Composition: Mtbptm1Glo/Mtbptm1Glo,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Mtbptm1Glo/Mtbptm1Glo,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

 MP:0011097 complete embryonic lethality before turning of embryo "death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith]
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Allelic Composition: Cdc7tm1Hmas/Cdc7tm1Hmas,Trp53tm2Mok/Trp53tm2Mok
Genetic Background: involves: 129S/Sv * C57BL/6

Allelic Composition: Rad51tm1Hst/Rad51tm1Hst,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Mdm2tm1Glo/Mdm2tm1Glo,Trp53tm1Adv/Trp53tm1Adv
Genetic Background: involves: 129S7/SvEvBrd

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Bard1tm1Thl/Bard1tm1Thl,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S1/Sv * 129S2/SvPas

Allelic Composition: Trp53tm1.1Att/Trp53+
Genetic Background: Not Specified

Allelic Composition: Npm1Gt(VICTR37)704Lex/Npm1Gt(VICTR37)704Lex,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Trp53bp2tm1Xlu/Trp53bp2tm1Xlu
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

Allelic Composition: Brca1tm1Cxd/Brca1tm1Cxd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Metap2tm1.2Ccr/Metap2tm1.2Ccr,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * FVB/N

Allelic Composition: Gnl3Gt(W223E05)Wrst/Gnl3Gt(W223E05)Wrst,Trp53tm1Tyj/Trp53tm5Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

Allelic Composition: Eloatm1Aso/Eloatm1Aso,Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: 129S/SvEv * C57BL/6 * CBA

Allelic Composition: Rev3ltm1Ndew/Rev3ltm1Ndew,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Brca1tm1Mak/Brca1tm1Mak,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

Allelic Composition: Pip4k2bGt(Betageo)1Lca/Pip4k2bGt(Betageo)1Lca,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd

 MP:0011099 complete lethality throughout fetal growth and development "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
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Allelic Composition: Npm1tm1Ppp/Npm1tm1Ppp,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Mdm4Gt(VICTR20)7Lex/Mdm4Gt(VICTR20)7Lex,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd

Allelic Composition: Nelfbtm1.2Roli/Nelfbtm1.2Roli,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Nelfbtm1.2Roli/Nelfbtm1.2Roli,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Mdm4tm1Glo/Mdm4tm1Glo,Trp53tm1Adv/Trp53tm1Adv
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Mdm4tm1Glo/Mdm4tm1Glo,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Cdkn2atm1.1Brn/Cdkn2atm1.1Brn,Pknox1tm1Fbla/Pknox1tm1Fbla,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Atmintm1.1Jhh/Atmintm1.1Jhh,Trp53tm1.1Brn/Trp53tm1.1Brn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Trp53tm8Xu/Trp53tm8Xu
Genetic Background: Not Specified

Allelic Composition: Ino80tm1.1Schg/Ino80tm1.1Schg,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Tfdp1tm1Lili/Tfdp1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Tg(ACTB-NOTCH1)1Shn/0,Tg(Nes-cre)1Kln/0,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Motp1CE/J/Motp1CE/J,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129-Trp53tm1Tyj/J * CE/J

Allelic Composition: Motp1CE/J/Motp1CE/J,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129-Trp53tm1Tyj/J * CE/J

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

Allelic Composition: Trp53tm1Tyj/Trp53tm3.1Tyj
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2tm1Xlu
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

Allelic Composition: Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Atrtm1Ofc/Atrtm1Ofc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

 MP:0011102 partial embryonic lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Sirt1tm1.1Cxd/Sirt1tm1.1Cxd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB/N)

Allelic Composition: Sirt1tm1.1Cxd/Sirt1tm1.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB/N)

Allelic Composition: Ino80tm1.1Schg/Ino80tm1.1Schg,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Dph1tm2Bhr/Dph1tm2Bhr,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Rbbp6tm1Xya/Rbbp6tm1Xya,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Kat2atm1Roth/Kat2atm1Roth,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Mdm4Gt(VICTR20)7Lex/Mdm4Gt(VICTR20)7Lex,Trp53tm1.1Xlu/Trp53tm1.1Xlu
Genetic Background: involves: 129S5/SvEvBrd * 129S6/SvEvTac * C57BL/6 * FVB/N

Allelic Composition: Mdm4Gt(VICTR20)7Lex/Mdm4+,Trp53tm1.1Xlu/Trp53tm1.1Xlu
Genetic Background: involves: 129S5/SvEvBrd * 129S6/SvEvTac * C57BL/6 * FVB/N

Allelic Composition: Trp53tm2.1Snj/Trp53tm2.1Snj
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0011109 partial lethality throughout fetal growth and development "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
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Allelic Composition: Sirt1tm1.1Cxd/Sirt1tm1.1Cxd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB/N)

Allelic Composition: Trp53tm2.1Snj/Trp53tm2.1Snj
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Dp(4D4Mit190-D4Mit51)1Aam/0,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0011276 increased tail pigmentation "visually detectable excess of pigment present on the tail surface" [MGI:csmith]
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Allelic Composition: Trp53tm1.1Tldo/Trp53+
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

 MP:0011400 complete lethality "all individuals of a given genotype in a population die before the end of the normal lifespan but time(s) of death are unspecified" [MGI:llw2]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Krt19tm1(cre/ERT)Ggu/Krt19+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac

 MP:0011638 abnormal mitochondrial chromosome morphology "any structrual anomaly of the chromosome found in the mitochondrion of a eukaryotic cell" [GO:0000262]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NCrj

 MP:0011703 increased fibroblast proliferation "greater the expansion rate of a fibroblast cell population by cell division" [MGI:csmith]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S7-Trp53tm3.1Glo

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Ccne1tm1Jro/?,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: either: (involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6J) or (involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * C57BL/6J)

Allelic Composition: Npm1tm1Ppp/Npm1+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Npm1Gt(VICTR37)704Lex/Npm1Gt(VICTR37)704Lex,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Wahl/Trp53tm1Wahl
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Mdm4Gt(VICTR20)7Lex/Mdm4Gt(VICTR20)7Lex,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd

Allelic Composition: Trp53tm3.1Glo/Trp53tm3.1Glo
Genetic Background: B6.129S7-Trp53tm3.1Glo

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm2.1Snj/Trp53tm2.1Snj
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm2.1Snj/Trp53+
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Trp53tm1.1Wgu/Trp53tm1.1Wgu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Trp53tm2.1Wgu/Trp53tm2.1Wgu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Krastm1.1Hbji/Krastm1.1Hbji,Trp53tm5Tyj/Trp53tm5Tyj
Genetic Background: involves: 129S4/SvJae

 MP:0011704 decreased fibroblast proliferation "reduction in the expansion rate of a fibroblast cell population by cell division" [MGI:csmith]
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Allelic Composition: Mdm4Gt(VICTR20)7Lex/Mdm4Gt(VICTR20)7Lex,Trp53tm3Wahl/Trp53tm3Wahl
Genetic Background: involves: 129S4/SvJae * 129S5/SvEvBrd

Allelic Composition: Gnl3tm2.1Rylt/Gnl3tm2.1Rylt,Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6 * CBA

 MP:0011804 increased cell migration "increased or faster movement of cells from one site to another, often occuring during developmental or chemotactic processes" [GO:0016477, MGI:csmith]
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Allelic Composition: Prkar1atm1.2Lsk/Prkar1a+,Rb1tm2Brn/Rb1+,Tg(Col1a1-cre)1Kry/0,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N

 MP:0011903 decreased hematopoietic stem cell proliferation "reduction in the expansion rate of a hematopoietic stem cell population by cell division" [MGI:csmith]
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Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0012043 increased myoepithelioma incidence "greater than the expected occurrence of a benign tumor of myoepithelial cells, occurring in a specific population in a given time period" [ISBN:0-683-40008-8]
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Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0012400 nail dystrophy "the presence of misshapen or partially destroyed nail plates, fequently with keratin often accumulating between the dystrophic nail plate and nail bed; often due to trauma or infection" [MGI:smb]
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Allelic Composition: Trp53tm1.1Tldo/Trp53tm1.1Tldo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6

 MP:0012411 increased granulosa cell tumor incidence "greater than the expected number of neoplasms derived from somatic cells of the sex cord in the ovary a given population in a given time period" [http://orcid.org/0000-0001-5208-3432]
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Allelic Composition: Ptentm1Hwu/Ptentm1Hwu,Trp53tm2Tyj/Trp53+,Amhr2tm3(cre)Bhr/Amhr2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd

Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,KitW-v/KitW-v,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0012415 decreased sarcoma incidence "less than the expected number of a connective tissue neoplasm associated with the proliferation of embryonically-derived mesodermal cells, occurring in a specific population in a given time period" [DOID:1115]
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Allelic Composition: Rbm38tm1.1Xch/Rbm38tm1.1Xch,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

Allelic Composition: Cpt1cGt(XL823)Byg/Cpt1c+,Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

 MP:0012431 increased lymphoma incidence "greater than the expected number of neoplasms characterized by a proliferation of malignant lymphocytes in lymphoid tissue in a specific population in a given time period" [http://orcid.org/0000-0001-5208-3432, MGI:csmith]
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: H2afxtm1Fwa/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm2Glo/Trp53tm2Glo
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Thbs1tm1Hyn/Thbs1tm1Hyn,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: H2afxtm1Nus/H2afxtm1Nus,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Trp53tm1Elee/Trp53tm1Elee,Tg(MMTV-cre)AElee/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Psmb9tm1Stl/Psmb9tm1Stl,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S7-Trp53tm3.1Glo

Allelic Composition: Nbntm2Zqw/Nbntm2Zqw,Trp53tm1Brd/Trp53tm1Brd,Tg(Nes-cre)1Wme/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Allelic Composition: Nf1tm1Fcr/Nf1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6

Allelic Composition: Trp53Bbl/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53Bbl/Anu

Allelic Composition: Trp53bhy/Trp53+
Genetic Background: C57BL/6JSfdAnu-Trp53bhy/Anu

Allelic Composition: Nbntm1Jpt/Nbntm1Jpt,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Stk11tm1.1Mlfr/Stk11+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Trp53tm1Tyj/Trp53+,Trp53bp2tm1Xlu/Trp53bp2+
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Xrcc2tm1Pmc/Xrcc2tm1Pmc
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Lig4tm1Fwa/Lig4tm1Fwa,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129S4/SvJae * FVB/N * SKH1

Allelic Composition: Trp53tm1.1Brn/Trp53tm3Tyj,Tg(KRT14-cre)8Brn/?
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB/N * SKH1

Allelic Composition: Trp53tm3.1Glo/Trp53tm3.1Glo
Genetic Background: B6.129S7-Trp53tm3.1Glo

Allelic Composition: SufuGt(XB699)Byg/Sufu+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Trp53tm4Xu/Trp53tm4Xu
Genetic Background: Not Specified

Allelic Composition: Fbxw7tm1Kei/Fbxw7tm1Kei,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Lck-cre)1Cwi/?
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Rb1tm1.1Jyjw/Rb1tm1.1Jyjw,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: 129S6.129-Trp53tm1Tyj Rb1tm1.1Jyjw

Allelic Composition: Mtbptm1Glo/Mtbp+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Sirt1tm1.1Cxd/Sirt1+,Trp53tm1Brd/Trp53+
Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB/N) or (involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * FVB/N)

Allelic Composition: Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Krastm2Tyj/Kras+,Trp53tm1Glo/Trp53+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Trp53tm1Brd/Trp53tm1Brd,Xrcc5tm1Dbr/Xrcc5tm1Dbr
Genetic Background: involves: 129S7/SvEvBrd * C57BL

Allelic Composition: Brca2tm1Mak/Brca2tm2Mak,Trp53tm1Brd/Trp53tm1Brd,Tg(Lck-cre)548Jxm/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

Allelic Composition: Trp53tm6Xu/Trp53tm6Xu,Tg(Lck-cre)1Cwi/0
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Trp53tm7.1Xu/Trp53tm7.1Xu
Genetic Background: Not Specified

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Mam/0
Genetic Background: involves: 129P2/OlaHsd * FVB

Allelic Composition: Irf1tm1Mak/Irf1tm1Mak,Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

Allelic Composition: Mdm2tm3.1Glo/Mdm2tm3.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo

Allelic Composition: Mdm2tm4.1Glo/Mdm2tm4.1Glo,Trp53tm3.1Glo/Trp53+
Genetic Background: B6.129S-Mdm2tm4.1Glo Trp53tm3.1Glo

Allelic Composition: Trp53tm1.1Xlu/Trp53tm1.1Xlu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * FVB/N

Allelic Composition: Dclre1atm1Rleg/Dclre1atm1Rleg,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Cd44tm1Mak/Cd44tm1Mak,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * C57BL/6J

Allelic Composition: Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+,Trp53tm1Brn/Trp53tm1Brn,Tg(MMTV-cre)#Tfln/0
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

Allelic Composition: Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+,Tg(MMTV-cre)#Tfln/0,Trp53tm1Brn/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

Allelic Composition: Trp53tm1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm4Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm3.1Glo/Trp53tm4Glo
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Rag2tm1.1Mss/Rag2tm1.1Mss,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Pinx1tm1.1Kplu/Pinx1+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

Allelic Composition: Espl1Gt(XL058)Byg/Espl1+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg

Allelic Composition: Trp53tm1Tyj/Trp53+,Uimc1tm1.2Amj/Uimc1tm1.2Amj
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6

Allelic Composition: Trp53tm1.1Thst/Trp53+,Tg(IghMyc)22Bri/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL * SJL

Allelic Composition: Trp53tm1Thst/Trp53+,Tg(IghMyc)22Bri/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL * SJL

Allelic Composition: Exo1tm3.1Wed/Exo1tm3.1Wed,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Rasal2Gt(463C12)Cmhd/Rasal2Gt(463C12)Cmhd,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S * 129X1/SvJ * C57BL/6 * C57BL/6NCrl

Allelic Composition: Rtel1tm2.1Hdin/Rtel1tm2.1Hdin,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

Allelic Composition: Tg(Mdm2)1Snj/0,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Rbm38tm1.1Xch/Rbm38tm1.1Xch,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6 * FVB/N

Allelic Composition: Nf1tm1Tyj/Nf1+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Nf1tm1Tyj/Nf1+,Suz12Gt(Betageo)1Khe/Suz12+,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Allelic Composition: Rps27lGt(IST11658B7)Tigm/Rps27lGt(IST11658B7)Tigm,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6N

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

Allelic Composition: Nabp2tm1Schg/Nabp2tm1Schg,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Trp53tm1Tyj/Trp53tm1.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

Allelic Composition: Trp53tm1Tyj/Trp53tm2.1Umol
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

 MP:0012690 abnormal stride length "abnormal average distance between steps" [MPD:Molly]
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Allelic Composition: Smarcb1tm2Sho/Smarcb1tm2Sho,Trp53tm1Brn/Trp53tm1Brn,Tg(GFAP-cre)#Gtm/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA

 MP:0013177 abnormal tail tip morphology "any structural anomaly of the distal end of the tail" [MGI:anna]
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Allelic Composition: Trp53tm1.1Manf/Trp53tm1.1Manf
Genetic Background: Not Specified

 MP:0013184 hemorrhagic ascites "the presence of bloody or blood-stained serous fluid, frequently resulting from metastatic carcinoma, in the peritoneal cavity" [MGI:anna]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm2Tyj/Trp53+,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Brca1tm1Brn/Brca1tm1Brn,Tg(Krt18-EGFP,-TAg121)36Ysng/0,Trp53tm1Brn/Trp53tm2Tyj
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N

Allelic Composition: Trp53tm1Brn/Trp53tm1Brn,Tsc1tm1Djk/Tsc1tm1Djk
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae

 MP:0013236 ovary degeneration "a retrogressive impairment of function or destruction of one or both ovaries" [MGI:anna]
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Allelic Composition: Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0013241 embryo tissue necrosis "morphological changes resulting from pathological death of some or all embryo tissue; usually due to irreversible damage" [MGI:csmith]
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Allelic Composition: Metap2tm1.2Ccr/Metap2tm1.2Ccr,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * FVB/N

 MP:0013502 decreased fibroblast apoptosis "reduction in the timing or the number of fibroblast cells undergoing programmed cell death" [MGI:csmith]
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Allelic Composition: Trp53tm1Wahl/Trp53tm1Wahl
Genetic Background: involves: C57BL/6

 MP:0013504 increased embryonic tissue cell apoptosis "increase in the timing or the number of cells in embryonic tissue undergoing programmed cell death" [MGI:csmith]
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Allelic Composition: Eloatm1Aso/Eloatm1Aso,Trp53tm1Sia/Trp53tm1Sia
Genetic Background: involves: 129S/SvEv * C57BL/6 * CBA

Allelic Composition: Atrtm1Ofc/Atrtm1Ofc,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Brca1tm2.1Cxd/Brca1tm2.1Cxd,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

 MP:0013505 decreased embryonic tissue cell apoptosis "decrease in the timing or the number of cells in embryonic tissue undergoing programmed cell death" [MGI:csmith]
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Allelic Composition: Kat2atm1Roth/Kat2atm1Roth,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J

 MP:0013539 increased ovary adenoma incidence "greater than the expected number of a benign epithelial neoplasm with a glandular organization arising in the ovary, occurring in a specific population in a given time period" [MGI:Anna]
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Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,KitW-v/KitW-v,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0013697 decreased granulocyte monocyte progenitor cell number "reduction in the number of a hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages; these cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1" [CL:0000557, PMID:16551251]
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Allelic Composition: Smim3tm1Anjm/Smim3+,Cd74tm1Anjm/Cd74+,Lmo2tm2(cre)Thr/Lmo2+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

 MP:0013705 decreased megakaryocyte-erythroid progenitor cell number "reduced number of a progenitor cell committed to the megakaryocyte and erythroid lineages" [CL:0000050]
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Allelic Composition: Smim3tm1Anjm/Smim3+,Cd74tm1Anjm/Cd74+,Lmo2tm2(cre)Thr/Lmo2+,Trp53tm1Brd/Trp53+
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

 MP:0013751 increased cystadenoma incidence "greater than the expected number of a histologically benign neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed, occurring in a specific population in a given time period; in some instances, considerable portions of the neoplasm, or even the entire mass, may be cystic" [http://medical-dictionary.thefreedictionary.com/cystoadenoma, MGI:Anna]
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Allelic Composition: Apctm2Rak/Apc+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)6Tuv/0
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

 MP:0014127 increased thymoma incidence "greater than the expected number of a malignant neoplasm originating from the epithelial cells of the thymus, occurring in a specific population in a given time period; thymoma is an uncommon tumor linked with myasthenia gravis and other autoimmune diseases" [http://medical-dictionary.thefreedictionary.com/thymoma, http://www.cancer.gov/cancertopics/pdq/treatment/thymoma/patient/page1#_139]
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Allelic Composition: Prkdcscid/Prkdc+,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Rnf168Gt(405F11)Cmhd/Rnf168Gt(405F11)Cmhd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Rnf168Gt(156B6)Cmhd/Rnf168Gt(156B6)Cmhd,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

 MP:0020386 adipose tissue inflammation "local accumulation of fluid, plasma proteins, and leukocytes in adipose tissue" [MGI:anna, PMID:24662293, PMID:24695736, PMID:26629401]
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Allelic Composition: Trp53tm1.2Awbr/Trp53tm1.2Awbr
Genetic Background: involves: C57BL/6

 MP:0020410 increased liposarcoma incidence "greater than the expected number of malignant tumors derived from primitive or embryonal lipoblastic cells; these may be composed of well-differentiated fat cells or may be dedifferentiated: myxoid, round-celled, or pleomorphic" [MESH:D008080, PMID:27573812]
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Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(Prrx1-FUS/DDIT3)1Mete/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * CBA

 MP:0030005 increased retinal apoptosis "increase in the number of cells in the retina undergoing programmed cell death" [MGI:anna]
Show

Allelic Composition: Rb1tm3Tyj/Rb1tm3Tyj,Trp53tm1Tyj/Trp53tm1Tyj,Tg(Nes-cre)1Atp/0
Genetic Background: involves: 129S2/SvPas * FVB/N

 MP:0030073 square face "facial contours, as viewed from the front, show a broad upper face/cranium and lower face/mandible, creating a square appearance" [HP:0000321]
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Allelic Composition: Tg(CMV-cre)1Cgn/0,Trp53tm4Att/Trp53+
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000006288 Ttc5 / Q99LG4 / tetratricopeptide repeat domain 5 / Q8N0Z6*  / reaction / complex
 ENSMUSG00000028630 Dyrk2 / Q5U4C9 / Dual specificity tyrosine-phosphorylation-regulated kinase 2 / Q92630*  / reaction
 ENSMUSG00000035576 A2A5N8 / L3mbtl1 / Lethal(3)malignant brain tumor-like protein 1 / Q9Y468* / L3MBTL1, histone methyl-lysine binding protein*  / complex / reaction
 ENSMUSG00000008730 Hipk1 / O88904 / Homeodomain-interacting protein kinase 1 / Q86Z02*  / complex / reaction
 ENSMUSG00000003068 Stk11 / Q9WTK7 / Serine/threonine-protein kinase STK11 / Q15831* / serine/threonine kinase 11*  / reaction / complex
 ENSMUSG00000001632 Brpf1 / B2RRD7 / Peregrin / P55201* / bromodomain and PHD finger containing 1*  / complex / reaction
 ENSMUSG00000031540 Kat6a / lysine acetyltransferase 6A / Q92794*  / reaction / complex
 ENSMUSG00000026510 Trp53bp2 / transformation related protein 53 binding protein 2 / Q13625* / TP53BP2* / tumor protein p53 binding protein 2*  / complex / reaction
 ENSMUSG00000031826 Usp10 / P52479 / ubiquitin specific peptidase 10 / Q14694*  / complex
 ENSMUSG00000051306 Usp42 / B2RQC2 / ubiquitin specific peptidase 42 / Q9H9J4*  / complex
 ENSMUSG00000023110 Prmt5 / protein arginine N-methyltransferase 5 / O14744* / protein arginine methyltransferase 5*  / complex / reaction
 ENSMUSG00000061436 Hipk2 / Q9QZR5 / homeodomain interacting protein kinase 2 / Q9H2X6*  / reaction / complex
 ENSMUSG00000021285 Q62415 / Ppp1r13b / protein phosphatase 1, regulatory (inhibitor) subunit 13B / Q96KQ4* / protein phosphatase 1 regulatory subunit 13B*  / reaction / complex
 ENSMUSG00000055024 Ep300 / B2RWS6 / Histone acetyltransferase p300 / Q09472* / E1A binding protein p300*  / complex / reaction
 ENSMUSG00000028863 Meaf6 / Q2VPQ9 / MYST/Esa1-associated factor 6 / Q9HAF1*  / reaction / complex
 ENSMUSG00000032171 Pin1 / Q9QUR7 / Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 / Q13526* / peptidylprolyl cis/trans isomerase, NIMA-interacting 1*  / complex / reaction
 ENSMUSG00000021690 Jmy / junction mediating and regulatory protein, p53 cofactor / Q8N9B5*  / complex / reaction
 ENSMUSG00000038116 Phf20 / Q8BLG0 / PHD finger protein 20 / Q9BVI0*  / reaction / complex
 ENSMUSG00000029505 Ep400 / Q8CHI8 / E1A-binding protein p400 / Q96L91*  / reaction / complex
 ENSMUSG00000028514 Usp24 / B1AY13 / ubiquitin specific peptidase 24 / Q9UPU5*  / complex
 ENSMUSG00000063049 Ing2 / Q9ESK4 / Inhibitor of growth protein 2 / Q9H160* / inhibitor of growth family member 2*  / complex / reaction
 ENSMUSG00000040782 Cop1 / Q9R1A8 / COP1, E3 ubiquitin ligase / Q8NHY2*  / complex
 ENSMUSG00000074997 Pin1rt1 / PIN1* / Q13526* / peptidylprolyl cis/trans isomerase, NIMA-interacting 1*  / reaction / complex
 ENSMUSG00000059552 Trp53 / P02340 / transformation related protein 53 / TP53* / P04637* / tumor protein p53*  / complex / reaction
 ENSMUSG00000020897 Aurkb / O70126 / Aurora kinase B / Q96GD4*  / complex / reaction
 ENSMUSG00000026283 Ing5 / Q9D8Y8 / Inhibitor of growth protein 5 / Q8WYH8* / inhibitor of growth family member 5*  / reaction / complex
 ENSMUSG00000031660 Brd7 / O88665 / Bromodomain-containing protein 7 / Q9NPI1* / bromodomain containing 7*  / complex / reaction
 ENSMUSG00000020184 Mdm2 / P23804 / E3 ubiquitin-protein ligase Mdm2 / Q00987* / MDM2 proto-oncogene*  / reaction / complex
 ENSMUSG00000020032 Nuak1 / Q641K5 / NUAK family SNF1-like kinase 1 / O60285* / NUAK family kinase 1*  / reaction / complex
 ENSMUSG00000013787 Ehmt2 / Q9Z148 / Histone-lysine N-methyltransferase EHMT2 / Q96KQ7* / euchromatic histone lysine methyltransferase 2*  / reaction
 ENSMUSG00000024387 Csnk2b / P67871 / Casein kinase II subunit beta / P67870* / casein kinase 2 beta*  / reaction
 ENSMUSG00000025316 Banp / Q8VBU8 / Protein BANP / Q8N9N5* / BTG3 associated nuclear protein*  / complex / reaction
 ENSMUSG00000025358 Cdk2 / P97377 / Cyclin-dependent kinase 2 / P24941*  / reaction
 ENSMUSG00000026603 Smyd2 / Q8R5A0 / N-lysine methyltransferase SMYD2 / Q9NRG4* / SET and MYND domain containing 2*  / reaction
 ENSMUSG00000039725 Trp53rka / transformation related protein 53 regulating kinase A / Q96S44* / TP53RK* / TP53 regulating kinase*  / reaction
 ENSMUSG00000028211 Q9QXE4 / Trp53inp1 / transformation related protein 53 inducible nuclear protein 1 / Q96A56* / TP53INP1* / tumor protein p53 inducible nuclear protein 1*  / reaction / complex
 ENSMUSG00000029513 Prkab1 / Q9R078 / protein kinase, AMP-activated, beta 1 non-catalytic subunit / Q9Y478* / protein kinase AMP-activated non-catalytic subunit beta 1*  / reaction
 ENSMUSG00000028969 Cdk5 / P49615 / Cyclin-dependent-like kinase 5 / Q00535* / cyclin dependent kinase 5*  / reaction
 ENSMUSG00000032409 Atr / ATR serine/threonine kinase / Q13535*  / reaction
 ENSMUSG00000027496 Aurka / P97477 / Aurora kinase A / O14965*  / reaction
 ENSMUSG00000031688 Pou4f2 / Q63934 / POU domain, class 4, transcription factor 2 / Q12837* / POU class 4 homeobox 2*  / reaction / complex
 ENSMUSG00000028944 Prkag2 / Q91WG5 / protein kinase, AMP-activated, gamma 2 non-catalytic subunit / Q9UGJ0* / protein kinase AMP-activated non-catalytic subunit gamma 2*  / reaction
 ENSMUSG00000028518 Prkaa2 / Q8BRK8 / protein kinase, AMP-activated, alpha 2 catalytic subunit / P54646* / protein kinase AMP-activated catalytic subunit alpha 2*  / reaction
 ENSMUSG00000029454 O54992 / Mapkapk5 / MAP kinase-activated protein kinase 5 / Q8IW41* / mitogen-activated protein kinase-activated protein kinase 5*  / reaction
 ENSMUSG00000032113 Chek1 / O35280 / Serine/threonine-protein kinase Chk1 / O14757* / checkpoint kinase 1*  / reaction
 ENSMUSG00000050697 Prkaa1 / Q5EG47 / protein kinase, AMP-activated, alpha 1 catalytic subunit / Q13131* / protein kinase AMP-activated catalytic subunit alpha 1*  / reaction
 ENSMUSG00000042854 Trp53rkb / Q96S44* / TP53RK* / TP53 regulating kinase*  / reaction
 ENSMUSG00000036893 Ehmt1 / Q5DW34 / Histone-lysine N-methyltransferase EHMT1 / Q9H9B1* / euchromatic histone lysine methyltransferase 1*  / reaction
 ENSMUSG00000070691 Runx3 / Q64131 / Runt-related transcription factor 3 / Q13761*  / complex / reaction
 ENSMUSG00000049327 Kmt5a / lysine methyltransferase 5A / Q9NQR1*  / reaction
 ENSMUSG00000048349 P17208 / Pou4f1 / POU domain, class 4, transcription factor 1 / Q01851* / POU class 4 homeobox 1*  / reaction / complex
 ENSMUSG00000054387 Mdm4 / O35618 / transformed mouse 3T3 cell double minute 4 / O15151* / MDM4, p53 regulator*  / reaction / complex
 ENSMUSG00000038205 Prkab2 / Q6PAM0 / protein kinase, AMP-activated, beta 2 non-catalytic subunit / O43741* / protein kinase AMP-activated non-catalytic subunit beta 2*  / reaction
 ENSMUSG00000025646 Atrip / Q8BMG1 / ATR-interacting protein / Q8WXE1*  / reaction
 ENSMUSG00000046707 O54833 / Csnk2a2 / Casein kinase II subunit alpha / P19784* / casein kinase 2 alpha 2*  / reaction
 ENSMUSG00000040734 Q5I1X5 / Ppp1r13l / protein phosphatase 1, regulatory (inhibitor) subunit 13 like / Q8WUF5* / protein phosphatase 1 regulatory subunit 13 like*  / reaction / complex
 ENSMUSG00000048895 Cdk5r1 / P61809 / Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 activator 1, p35 Cyclin-dependent kinase 5 activator 1, p25 / Q15078* / cyclin dependent kinase 5 regulator...  / reaction
 ENSMUSG00000029521 Chek2 / Q9Z265 / Serine/threonine-protein kinase Chk2 / O96017* / checkpoint kinase 2*  / reaction
 ENSMUSG00000006542 Prkag3 / Q8BGM7 / protein kinase, AMP-activated, gamma 3 non-catatlytic subunit / Q9UGI9* / protein kinase AMP-activated non-catalytic subunit gamma 3*  / reaction
 ENSMUSG00000036986 Pml / Q60953 / Protein PML / P29590* / promyelocytic leukemia*  / reaction / complex
 ENSMUSG00000028680 Plk3 / serine/threonine-protein kinase PLK3 isoform 2 / Q9H4B4* / polo like kinase 3*  / reaction
 ENSMUSG00000031314 Taf1 / Q80UV9 / TATA-box binding protein associated factor 1 / TAF1L* / Q8IZX4* / P21675* / TATA-box binding protein associated factor 1 like*  / reaction
 ENSMUSG00000034218 Atm / Q62388 / Serine-protein kinase ATM / Q13315* / ATM serine/threonine kinase*  / reaction
 ENSMUSG00000022710 Usp7 / ubiquitin specific peptidase 7 / Q93009*  / reaction
 ENSMUSG00000067713 O54950 / Prkag1 / protein kinase, AMP-activated, gamma 1 non-catalytic subunit / P54619* / protein kinase AMP-activated non-catalytic subunit gamma 1*  / reaction
 ENSMUSG00000000552 Q8VD12 / Zfp385a / zinc finger protein 385A / Q96PM9* / ZNF385A*  / reaction / complex
 ENSMUSG00000095567 Noc2l / NOC2 like nucleolar associated transcriptional repressor / Q9Y3T9*  / complex / reaction
 ENSMUSG00000022385 Gtse1 / Q8R080 / G2 and S phase-expressed protein 1 / Q9NYZ3* / G2 and S-phase expressed 1*  / complex / reaction
 ENSMUSG00000101523 Q60737 / Gm10031 / predicted pseudogene 10031 / Q8NEV1* / P68400* / CSNK2A1* / CSNK2A3* / casein kinase 2 alpha 1* / casein kinase 2 alpha 3*  / reaction






 

2 s.

 
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