ENSMUSG00000028514


Mus musculus

Features
Gene ID: ENSMUSG00000028514
  
Biological name :Usp24
  
Synonyms : B1AY13 / ubiquitin specific peptidase 24 / Usp24
  
Possible biological names infered from orthology : Q9UPU5
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: C7
Gene start: 106316213
Gene end: 106441322
  
Corresponding Affymetrix probe sets: 10506500 (MoGene1.0st)   10506569 (MoGene1.0st)   1441018_at (Mouse Genome 430 2.0 Array)   1448013_at (Mouse Genome 430 2.0 Array)   1448014_s_at (Mouse Genome 430 2.0 Array)   1452868_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000133095
Ensembl peptide - ENSMUSP00000092538
NCBI entrez gene - 329908     See in Manteia.
MGI - MGI:1919936
RefSeq - XM_006503180
RefSeq - XM_006503177
RefSeq - XM_006503178
RefSeq - XM_006503179
RefSeq - NM_183225
RefSeq - XM_006503176
RefSeq Peptide - NP_899048
swissprot - E9PV45
swissprot - B1AY13
Ensembl - ENSMUSG00000028514
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 USP24ENSGALG00000010805Gallus gallus
 USP24ENSG00000162402Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Usp9x / ubiquitin specific peptidase 9, X chromosome / Q93008* / ubiquitin specific peptidase 9, X-linked*ENSMUSG0000003101030
Usp9y / ubiquitin specific peptidase 9, Y chromosome / O00507* / ubiquitin specific peptidase 9, Y-linked*ENSMUSG0000006904429
Usp34 / Q6ZQ93 / ubiquitin specific peptidase 34 / Q70CQ2*ENSMUSG0000005634220
Usp47 / Q8BY87 / ubiquitin specific peptidase 47 / Q96K76*ENSMUSG000000592636
Usp48 / Q3V0C5 / ubiquitin specific peptidase 48 / Q86UV5*ENSMUSG000000434116
Usp7 / ubiquitin specific peptidase 7 / Q93009*ENSMUSG000000227106
Usp40 / Q8BWR4 / ubiquitin specific peptidase 40 / Q9NVE5*ENSMUSG000000055016
Usp18 / Q9WTV6 / ubiquitin specific peptidase 18 / USP41* / Q9UMW8* / Q3LFD5* / ubiquitin specific peptidase 41*ENSMUSG000000301073


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR009060  UBA-like superfamily
 IPR011989  Armadillo-like helical
 IPR015940  Ubiquitin-associated domain
 IPR016024  Armadillo-type fold
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR033382  Ubiquitin-specific peptidase 24


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000195 hypocalcemia "subnormal concentrations of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Nbeal2tm1a(EUCOMM)Wtsi/Nbeal2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nbeal2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Nbeal2tm1a(EUCOMM)Wtsi/Nbeal2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nbeal2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0002591 decreased mean corpuscular volume "less than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Nbeal2tm1a(EUCOMM)Wtsi/Nbeal2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nbeal2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0002834 decreased heart weight "less than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]
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Allelic Composition: Nbeal2tm1a(EUCOMM)Wtsi/Nbeal2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nbeal2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Nbeal2tm1a(EUCOMM)Wtsi/Nbeal2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nbeal2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0005567 decreased circulating total protein level "less than the average total concentration of these macromolecules in the blood " [RGD:Rat Genome Database submission]
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Allelic Composition: Nbeal2tm1a(EUCOMM)Wtsi/Nbeal2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nbeal2tm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000059552 Trp53 / P02340 / transformation related protein 53 / TP53* / P04637* / tumor protein p53*  / complex
 ENSMUSG00000002109 Ddb2 / Q99J79 / DNA damage-binding protein 2 / Q92466* / damage specific DNA binding protein 2*  / complex






 

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