ENSMUSG00000056342


Mus musculus

Features
Gene ID: ENSMUSG00000056342
  
Biological name :Usp34
  
Synonyms : Q6ZQ93 / ubiquitin specific peptidase 34 / Usp34
  
Possible biological names infered from orthology : Q70CQ2
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: A3.2
Gene start: 23306895
Gene end: 23490560
  
Corresponding Affymetrix probe sets: 10374621 (MoGene1.0st)   1434392_at (Mouse Genome 430 2.0 Array)   1434393_at (Mouse Genome 430 2.0 Array)   1444437_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120747
Ensembl peptide - ENSMUSP00000121426
Ensembl peptide - ENSMUSP00000137430
Ensembl peptide - ENSMUSP00000115168
NCBI entrez gene - 17847     See in Manteia.
MGI - MGI:109473
RefSeq - XM_006514566
RefSeq - XM_017314317
RefSeq - NM_001190401
RefSeq - XM_006514568
RefSeq - XM_006514565
RefSeq - XM_006514567
RefSeq Peptide - NP_001177330
swissprot - Q6ZQ93
swissprot - F6WJB7
swissprot - Z4YLQ1
swissprot - Z4YN11
Ensembl - ENSMUSG00000056342
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 USP34ENSDARG00000102252Danio rerio
 USP34ENSGALG00000004455Gallus gallus
 USP34ENSG00000115464Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Usp24 / B1AY13 / ubiquitin specific peptidase 24 / Q9UPU5*ENSMUSG0000002851415
Usp9x / ubiquitin specific peptidase 9, X chromosome / Q93008* / ubiquitin specific peptidase 9, X-linked*ENSMUSG0000003101015
Usp9y / ubiquitin specific peptidase 9, Y chromosome / O00507* / ubiquitin specific peptidase 9, Y-linked*ENSMUSG0000006904414
Usp47 / Q8BY87 / ubiquitin specific peptidase 47 / Q96K76*ENSMUSG000000592636
Usp7 / ubiquitin specific peptidase 7 / Q93009*ENSMUSG000000227105
Usp40 / Q8BWR4 / ubiquitin specific peptidase 40 / Q9NVE5*ENSMUSG000000055015
Usp48 / Q3V0C5 / ubiquitin specific peptidase 48 / Q86UV5*ENSMUSG000000434115
Usp18 / Q9WTV6 / ubiquitin specific peptidase 18 / USP41* / Q9UMW8* / Q3LFD5* / ubiquitin specific peptidase 41*ENSMUSG000000301072


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016579 protein deubiquitination ISO
 biological_processGO:0071108 protein K48-linked deubiquitination IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity ISO


Pathways (from Reactome)
Pathway description
TCF dependent signaling in response to WNT
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024811 Tnks2 / Q3UES3 / Tankyrase-2 / Q9H2K2*  / reaction
 ENSMUSG00000031529 Tnks / Q6PFX9 / tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase / O95271* / tankyrase*  / reaction
 ENSMUSG00000000142 Axin2 / O88566 / Q9Y2T1*  / reaction
 ENSMUSG00000024182 Axin1 / O15169*  / reaction
 ENSMUSG00000038876 Q9CZW6 / Rnf146 / ring finger protein 146 / Q9NTX7*  / reaction






 

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