| MP:0000111 | cleft palate | "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Ccnd3tm1Pisc/Ccnd3tm1Pisc,Rb1tm2Brn/Rb1tm2Brn,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129 * C57BL/6 * CBA
|
| MP:0000117 | absent tooth primordium | "missing the cells that will give rise to teeth" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0000124 | absent teeth | "missing bony structures of the upper and lower jaws used in mastication" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
|
| MP:0000160 | kyphosis | "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Tg(KRT5-cre/PGR)1Der/0,Trp63tm2Brd/Trp63tm3.1Brd
Genetic Background: involves: 129S7/SvEvBrd * FVB * ICR
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
|
| MP:0000352 | decreased cell proliferation | "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Trp63tm3.1Brd/Trp63tm3.1Brd
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0000378 | absent hair follicles | "missing epidermal invaginations from which the hair shaft develops" [J:65039] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm3.2Brd/Trp63tm3.2Brd
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: Not Specified
|
| MP:0000379 | reduced hair follicle number | "fewer number of the epidermal invaginations from which the hair shaft develops" [J:15108] |
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Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
|
| MP:0000414 | alopecia | "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796] |
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Allelic Composition: Tg(KRT5-cre/PGR)1Der/0,Trp63tm2Brd/Trp63tm3.1Brd
Genetic Background: involves: 129S7/SvEvBrd * FVB * ICR
Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0000428 | abnormal craniofacial morphology | "anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Trp63tm1Aam/Trp63tm1Aam
Genetic Background: Not Specified
Allelic Composition: Tg(KRT5-cre/PGR)1Der/0,Trp63tm2Brd/Trp63tm3.1Brd
Genetic Background: involves: 129S7/SvEvBrd * FVB * ICR
Allelic Composition: Trp63tm1.1(cre)Ssig/Trp63tm1.1(cre)Ssig
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: Trp63m1Mhda/Trp63m1Mhda
Genetic Background: C3HeB/FeJ-Trp63m1Mhda
|
| MP:0000468 | abnormal esophageal epithelium morphology | "malformation of the epithelial layer of the esophagus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
Allelic Composition: Trp63tm1.1(cre)Ssig/Trp63tm1.1(cre)Ssig
Genetic Background: involves: 129S/SvEv * C57BL/6
|
| MP:0000469 | abnormal esophageal squamous epithelium morphology | "malformation of the scaly epithelial layer of the esophagus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc, J:54637] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm1Fmc/Trp63tm1Fmc
Genetic Background: involves: 129S4/SvJae * C57BL/6
|
| MP:0000471 | abnormal stomach epithelium morphology | "malformation of the epithelial layer of the stomach " [tc:Teresa Chu , Mouse Genome Informatics Curator] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0000472 | abnormal stomach squamous epithelium morphology | "malformation of the scaly epithelial layer of the stomach" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc, J:54637] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0000492 | abnormal rectum morphology | "structural aberration in the terminal portion of the intestinal tube adjacent to the anus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0000493 | rectal prolapse | "downward movement and external appearance of the rectum through the anus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0000539 | distended urinary bladder | "stretched musculomembranous bag for holding urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
|
| MP:0000540 | abnormal urinary bladder epithelium morphology | "malformation of the epithelial layer of the urinary bladder" [MGI:tc] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
|
| MP:0000543 | absent urinary bladder transitional epithelium | "missing the transitional epithelial layer of the urinary bladder" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
|
| MP:0000544 | thin urinary bladder transitional epithelium | "decrease in the thickness of the transitional epithelial layer of the urinary bladder" [MGI:tc, J:54637] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0000549 | absent limbs | "missing extremities" [J:51966, J:50768] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm1.1(cre)Ssig/Trp63tm1.1(cre)Ssig
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: Trp63m1Mhda/Trp63m1Mhda
Genetic Background: C3HeB/FeJ-Trp63m1Mhda
|
| MP:0000550 | abnormal forelimb morphology | "malformation of the entire anterior extremities" [MGI:tc] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Aam/Trp63tm1Aam
Genetic Background: Not Specified
Allelic Composition: Trp63tm3.2Brd/Trp63tm3.2Brd
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0000553 | absent radius | "missing the short bone of the lateral forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54637] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
|
| MP:0000555 | absent carpal bone | "missing the wrist bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54637] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
|
| MP:0000557 | absent hindlimb | "missing the entire posterior extremities" [MGI:tc, J:54637] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Aam/Trp63tm1Aam
Genetic Background: Not Specified
Allelic Composition: Trp63tm3.2Brd/Trp63tm3.2Brd
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0000561 | adactyly | "missing all digits; usually refered to as a congenital condition" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0000564 | syndactyly | "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Dlx5tm1Levi/Dlx5/Dlx6tm1Levi,Trp63tm1Aam/Trp63tm1Aam
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Trp63tm1Aam/Trp63tm1Aam,Dlx5tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0000614 | absent salivary gland | "missing any of the saliva-secreting glands of the oral cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc, J:54637] |
Show
Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0000629 | absent mammary gland | "missing milk-secreting glands of the breast" [J:18378] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0000648 | absent sebaceous gland | "missing the holocrine glands of the dermis that secrete sebum into the hair follicles" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: Not Specified
|
| MP:0000702 | enlarged lymph nodes | "lymph nodes of increased size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0000746 | weakness | "state of being infirm or less strong than littermates" [J:45400] |
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Allelic Composition: Tg(KRT5-cre/PGR)1Der/0,Trp63tm2Brd/Trp63tm3.1Brd
Genetic Background: involves: 129S7/SvEvBrd * FVB * ICR
|
| MP:0000753 | paralysis | "loss of power of voluntary movement in a muscle through injury or disease of its nerve supply" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0000764 | abnormal tongue epithelium morphology | "malformation of the epithelial layer of the tongue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc] |
Show
Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0000766 | absent tongue squamous epithelium | "missing the scaly epithelial layer of the tongue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637] |
Show
Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0001119 | abnormal female reproductive anatomy | "anomalous structure of the organs associated with producing offspring in the gender that bears the offspring" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S4/SvJae
|
| MP:0001137 | abnormal cervical epithelium | "malformation of the epithelial layer of the cervix" [MGI:tc] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0001140 | abnormal vaginal epithelium | "malformation of the epithelial layer of the vagina" [J:54637, tc:Teresa Chu , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0001159 | absent prostate gland | "missing gland in males that secretes part of the seminiferous fluid" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66126] |
Show
Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0001191 | abnormal skin condition | "anomalous state of the skin" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Pdgfatm1Cbet/Pdgfatm1Cbet,Pdgfctm1Nagy/Pdgfctm1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
|
| MP:0001196 | shiny skin | "skin with a glossy or glistening appearance" [J:56641] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
|
| MP:0001201 | translucent skin | "skin that is more transparent to light than normal " [J:15108] |
Show
Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
|
| MP:0001208 | blistering | "accumulation of fluid- filled thin walled structures under the epidermis or within the epidermis" [J:65039] |
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Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
Allelic Composition: Trp63tm1Cmis/Trp63+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0001209 | spontaneous skin ulceration | "unpredictable appearance of skin lesions, usually with inflammation" [J:65302] |
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Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
|
| MP:0001211 | wrinkled skin | "irregular folds and/or indentations on the skin" [J:19212] |
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Allelic Composition: Trp63tm2.2Elrf/Trp63+
Genetic Background: Not Specified
|
| MP:0001212 | skin lesions | "focal patches of inflammation on the skin" [J:30162] |
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Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0001216 | abnormal epidermal layer morphology | "anomalous structure or development of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Pdgfatm1Cbet/Pdgfatm1Cbet,Pdgfctm1Nagy/Pdgfctm1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Tg(KRT5-cre/PGR)1Der/0,Trp63tm2Brd/Trp63tm3.1Brd
Genetic Background: involves: 129S7/SvEvBrd * FVB * ICR
Allelic Composition: Trp63tm1Cmis/Trp63+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Trp63tm2.2Elrf/Trp63tm2.2Elrf
Genetic Background: Not Specified
|
| MP:0001217 | absent epidermis | "missing the epidermal cell layer in the skin" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637] |
Show
Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: Not Specified
Allelic Composition: Trp63tm1.1(cre)Ssig/Trp63tm1.1(cre)Ssig
Genetic Background: involves: 129S/SvEv * C57BL/6
|
| MP:0001231 | abnormal basal cell layer morphology | "structural anomaly of the deepest layer of the epidermis, which is composed of dividing stem cells and anchoring cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm2.2Elrf/Trp63tm2.2Elrf
Genetic Background: Not Specified
Allelic Composition: Trp63tm2.2Elrf/Trp63+
Genetic Background: Not Specified
|
| MP:0001236 | abnormal spinous layer morphology | "structual or developmental anomaly of the layer of polyhedral cells in the epidermis; shrinkage and adhesion of these cells gives a spiny or prickly appearance" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm2.2Elrf/Trp63tm2.2Elrf
Genetic Background: Not Specified
|
| MP:0001241 | absent cornified layer | "missing the outer layer of the epidermis, composed of several layers of keratinized non-nucleated cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
|
| MP:0001263 | weight loss | "progressive reduction of body weight below normal average for age" [J:45400] |
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Allelic Composition: Tg(KRT5-cre/PGR)1Der/0,Trp63tm2Brd/Trp63tm3.1Brd
Genetic Background: involves: 129S7/SvEvBrd * FVB * ICR
|
| MP:0001270 | distended abdomen | "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Tg(KRT5-cre/PGR)1Der/0,Trp63tm2Brd/Trp63tm3.1Brd
Genetic Background: involves: 129S7/SvEvBrd * FVB * ICR
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| MP:0001272 | increased metastatic potential | |
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Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
|
| MP:0001284 | absent vibrissae | "missing whiskers" [J:18378] |
Show
Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0001341 | absent eyelids | "missing skin folds covering the front of the eyeball when closed" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790] |
Show
Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0001347 | absent lacrimal glands | "missing the glands that secrete tears" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0001394 | circling | "repeated, compulsive movement in a circle; often associated with inner ear defects" [MGI:CLS, J:61295] |
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Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0001429 | dehydration | "excessive water loss from the body or from an organ or bodily part" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50053] |
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Allelic Composition: Dync2h1b2b414Clo/Dync2h1b2b414Clo
Genetic Background: C57BL/6J-Dync2h1b2b414Clo
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| MP:0001672 | abnormal embryogenesis/ development | "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Dync2h1b2b414Clo/Dync2h1b2b414Clo
Genetic Background: C57BL/6J-Dync2h1b2b414Clo
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| MP:0001675 | abnormal ectoderm development | "failure or abnormality in the formation of the ectoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Trp63tm1Aam/Trp63tm1Aam
Genetic Background: Not Specified
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| MP:0001676 | abnormal apical ectodermal ridge | "malformation of the multilayered ectodermal region at the tip of a limb bud necessary for the proper development of the underlying mesenchyme" [MGI:tc] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Trp63tm1Aam/Trp63tm1Aam
Genetic Background: Not Specified
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| MP:0001677 | absent apical ectodermal ridge | "missing the multilayered ectodermal region at the tip of a limb bud necessary for the proper development of the underlying mesenchyme" [J:54637] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0001792 | impaired wound healing | "reduced ability or inability to self-repair and close wounds" [J:65302, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
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| MP:0001859 | kidney inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0001874 | acanthosis | "diffuse hyperplasia of the spinous layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0001883 | mammary adenocarcinoma | "higher than normal incidence of malignant tumors of the mammary gland" [J:62919] |
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Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
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| MP:0001914 | hemorrhage | "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0002018 | malignant tumors | "higher than normal incidence of locally invasive, destructive and metastatic tumors " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:44427] |
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Allelic Composition: Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0002020 | increased tumor incidence | "greater than average number of tumors, usually a specific type" [MGI:cls, J:34193] |
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Allelic Composition: Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
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| MP:0002024 | T cell derived lymphoma | "group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
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| MP:0002027 | lung adenocarcinoma | "malignant neoplasm of epithelial cells in the lung" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:18542] |
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Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0002036 | rhabdomyosarcoma | "malignant tumor derived from skeletal (striated) muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58877] |
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Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
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| MP:0002038 | carcinoma | "malignant neoplasm arising from epithelial cells, usually glandular or squamous" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877] |
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Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0002048 | lung adenoma | "benign epithelial neoplasm of the lung" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:57631] |
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Allelic Composition: Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0002060 | abnormal skin morphology | "malformation or atypical structure of the membranous protective covering of the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:56777] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Tg(KRT5-cre/PGR)1Der/0,Trp63tm2Brd/Trp63tm3.1Brd
Genetic Background: involves: 129S7/SvEvBrd * FVB * ICR
Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: involves: C57BL/6
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| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Tg(KRT5-cre/PGR)1Der/0,Trp63tm2Brd/Trp63tm3.1Brd
Genetic Background: involves: 129S7/SvEvBrd * FVB * ICR
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
Allelic Composition: Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
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| MP:0002109 | abnormal limb morphology | "abnormal development of limbs resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Tg(KRT5-cre/PGR)1Der/0,Trp63tm2Brd/Trp63tm3.1Brd
Genetic Background: involves: 129S7/SvEvBrd * FVB * ICR
Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: involves: C57BL/6
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| MP:0002115 | abnormal skeleton extremities morphology | "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Pdgfatm1Cbet/Pdgfatm1Cbet,Pdgfctm1Nagy/Pdgfctm1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0002160 | abnormal reproductive system morphology | "structural or developmental anomaly of any of the tissues involved in the reproductive system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Pdgfatm1Cbet/Pdgfatm1Cbet,Pdgfctm1Nagy/Pdgfctm1Nagy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Trp63tm1Aam/Trp63tm1Aam,Dlx5tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Trp63tm1.1(cre)Ssig/Trp63+
Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: Trp63m1Mhda/Trp63+
Genetic Background: C3HeB/FeJ-Trp63m1Mhda
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| MP:0002285 | abnormal tracheal ciliated epithelium morphology | "structural anomaly of the epithelial lining of the trachea which contains numerous ciliated cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology:ISBN 0-397-51047-0] |
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Allelic Composition: Cd44tm1Hbg/Cd44tm1Hbg,Tg(TNF)197Gkl/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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| MP:0002406 | increased susceptibility to infection | "greater likelihood that an organism will develop ill effects from a pathogenic invasion or from components of or toxins produced by pathogens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Tg(KRT5-cre/PGR)1Der/0,Trp63tm2Brd/Trp63tm3.1Brd
Genetic Background: involves: 129S7/SvEvBrd * FVB * ICR
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| MP:0002637 | small uterus | "reduced size of the female muscular organ of gestation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S4/SvJae
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| MP:0002655 | abnormal keratinocyte morphology | "structural or developmental anomaly of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: Not Specified
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| MP:0002656 | abnormal keratinocyte differentiation | "developmental anomaly of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum
" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: Not Specified
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| MP:0002796 | impaired skin barrier function | "impaired ability of the skin to regulate water loss; frequently leads to dehydration" [J:56641] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0003125 | abnormal septation of the cloaca | "absence of or reduction in the separation of the single opening of the digestive, urinary, and reproductive tracts (cloaca) into mutliple isolated openings during development, may result in hypospadia, reduced anogenital distance, or persistent cloaca" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91491] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0003160 | abnormal esophageal development | "aberrant formation of the part of the digestive canal through which food passes from the pharynx to the stomach" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Trp63tm1Fmc/Trp63tm1Fmc
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0003257 | abnormal abdominal wall | "malformation in the margins that enclose the abdominal cavity; the major part is muscular but also includes skin, subcutaneous fat, fascia and the parietal peritoneum" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0003320 | rectovaginal fistula | "an abnormal anatomical passage connecting the rectum and the vagina " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0003384 | abnormal ventral body wall | "malformation in the anterior portion of a human body or the lower surface of an animal body comprised of ectoderm and mesoderm layers that encloses the body cavity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0003453 | abnormal keratinocyte physiology | "atypical function of the cells of the epidermis that produce keratin" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:94860] |
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Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: Not Specified
Allelic Composition: Trp63tm1Cmis/Trp63+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0003575 | absent oviduct | "absence of the tube through which the ova pass from the ovary to the uterus" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0003578 | absent ovary | "absence of the female reproductive gland containing the germ cells" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0003667 | hemangiosarcoma | "a malignant tumor characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and appear as irregular blood-filled or lumpy sacs that are typically filled with blood; rupture of the tumor can cause rapid death from bleeding" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:53511] |
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Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0003675 | kidney cysts | "abnormal membranous sacs in any portion of the pair of organs responsible for urine secretion" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
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| MP:0003704 | abnormal hair follicle development | "anomalous development of the epidermis from which the hair shaft develops " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0003743 | abnormal facial morphology | "anomalous structure or development of the face" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0003786 | premature aging | "earlier than normal occurence of the normal signs of aging" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:97764] |
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Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
Allelic Composition: Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
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| MP:0003789 | osteosarcoma | "malignant neoplasm derived from bone" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
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| MP:0003800 | monodactyly | "having only one toe or digit on each extremity" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Dlx5tm1Levi/Dlx5/Dlx6tm1Levi,Trp63tm1Aam/Trp63tm1Aam
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Trp63tm1Aam/Trp63tm1Aam,Dlx5tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: involves: 129P2/OlaHsd
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| MP:0003809 | abnormal hair shaft morphology | "irregular or unusual structure of the cuticle, and/or cortex and/or medulla of a hair" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0003935 | abnormal craniofacial development | "anomaly in the process of forming the face and/or cranium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: Not Specified
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| MP:0003941 | abnormal skin development | "anomaly in the formation of of the membranous protective covering of the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: Not Specified
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| MP:0004024 | aneuploidy | "chromosome count is not an exact multiple of the haploid number " [llw2:Linda Washburn , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
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| MP:0004200 | reduced fetal size | "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: Not Specified
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| MP:0004207 | squamous cell carcinoma | "a carcinoma that arises from stratified squamous epithelium that occurs in sites where glandular or columnar epithelium is normally present, such as the skin, esophagus, lungs and cervix" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
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| MP:0004228 | decreased cellular sensitivity to ionizing radiation | "decreased incidence of cell death following exposure to high levels of ionizing radiation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cdkn1atm1Tyj/Cdkn1atm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0004360 | absent ulna | "missing the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0004509 | abnormal pelvic girdle bone morphology | "any structural anomaly of the bones of the pelvis by which the limbs attach to the axial skeleton " [MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0004540 | small maxilla | "reduced size of the upper bony framework of the mouth where the superior teeth are held" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0004575 | small limb buds | "reduced size of the mesenchymal outgrowth on the lateral trunk of the embryo that develops into the limbs" [MESH:National Library of Medicine_Medical Subject Headings] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Aam/Trp63tm1Aam
Genetic Background: Not Specified
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| MP:0004592 | small mandible | "reduced size of the lower bony framework of the mouth where the inferior teeth are held" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0004684 | intervertebral disk degeneration | "retrogressive pathological change of the cartilaginous and gelatinous structure found between vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
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| MP:0005034 | abnormal anus morphology | "structural anomaly of the lower opening of the digestive tract" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0005213 | gastric metaplasia | "condition in which there is a change of one adult cell type to another adult cell type in the stomach " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:77398] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0005230 | ectrodactyly | "absence of the middle rays, i.e., the central digits of the paws; usually associated with cleft paws and may also include syndactyly or aplasia of remaining digits" [OMIM:Online Mendelian Inheritance in Man] |
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Allelic Composition: Trp63tm1Aam/Trp63tm1Aam
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5/Dlx6tm1Levi,Trp63tm1Aam/Trp63tm1Aam
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Trp63tm1Aam/Trp63tm1Aam,Dlx5tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: involves: 129P2/OlaHsd
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| MP:0005296 | abnormal humerus morphology | "malformation of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0005306 | abnormal phalanx morphology | "aberrant structure of any of the long bones of the digits" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Aam/Trp63+
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5/Dlx6tm1Levi,Trp63tm1Aam/Trp63tm1Aam
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Trp63tm1Aam/Trp63tm1Aam,Dlx5tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: involves: 129P2/OlaHsd
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| MP:0005481 | chronic myelocytic leukemia | "a heterogeneous group of myeloproliferative disorders that may evolve into acute leukemia in late stages " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
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| MP:0005494 | esophagogastric junction metaplasia | "conversion of one differentiated cell type to another differentiated cell type at the terminal end of the esophagus and beginning of the stomach" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:48446] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0005501 | abnormal skin physiology | "atypical function of the membranous protective covering of the body" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: either: (involves: 129S2/SvPas * C57BL/6 * FVB/N) or (involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6)
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| MP:0005650 | abnormal limb bud morphology | "aberrant structure or development of any of the swellings on the trunk of the embryo that become limbs" [hdene:Howard Dene , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:61460] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0006000 | abnormal corneal epithelium | "malformation in the one or more of the layers of epithelial cells covering the front of the cornea" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0006036 | abnormal mitochondrial physiology | |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0006042 | increased apoptosis | "greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0006043 | decreased apoptosis | "less than normal cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0006279 | abnormal limb development | "anomaly in the formation of the limbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: Not Specified
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| MP:0008007 | abnormal cellular replicative senescence | "anomaly in the process in which a cell progresses from its inception to the end of its lifespan, which occurs as the cell continues cycles of growth and division" [GO:0001302, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Adam15tm2.1Bbl/Adam15tm2.1Bbl
Genetic Background: involves: 129/SvJ * 129P2/OlaHsd * C57BL/6J * SJL
Allelic Composition: Trp63tm2.1Aam/Trp63tm2.1Aam
Genetic Background: Not Specified
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| MP:0008008 | early cellular replicative senescence | "increase in the progression of the process in which a cell progresses from its inception to the end of its lifespan, which occurs as the cell continues cycles of growth and division" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Trp63tm3.1Brd/Trp63tm3.1Brd
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Tg(KRT5-cre/PGR)1Der/0,Trp63tm2Brd/Trp63tm3.1Brd
Genetic Background: involves: 129S7/SvEvBrd * FVB * ICR
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: either: (involves: 129S2/SvPas * C57BL/6 * FVB/N) or (involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6)
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| MP:0008789 | abnormal olfactory epithelium morphology | "any structural anomaly in the epithelial cells that line the interior of the nose" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: involves: C57BL/6
Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: B6.129S7-Trp63tm2Brd/J
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| MP:0008866 | chromosomal instability | "abnormalities of DNA metabolism, DNA repair, cell-cycle governance, or control of apoptosis that increase the probability that whole chromosomes or pieces of chromosomes are gained or lost during cell division, resulting in an imbalance in the number of chromosomes per cell (aneuploidy) and an enhanced rate of loss of heterozygosity" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:12446840] |
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Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
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| MP:0009101 | clitoris hypoplasia | "underdevelopment or reduced size of the clitoris, usually due to a reduced number of cells" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0009228 | cervix inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the cervix" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0009321 | histiocytic sarcoma | |
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Allelic Composition: Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0009551 | urinary bladder transitional cell carcinoma | "a malignant neoplasm of the transitional epithelial layer of the urinary bladder" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp53tm1Tyj/Trp53+,Trp63tm1Fmc/Trp63+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
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| MP:0009560 | absent epidermis stratum granulosum | "absence of the layer of flattened cells containing basophilic granules of keratohyalin and lying just above the stratum spinosum (spiny layer) of the epidermis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0009575 | abnormal pubic symphysis morphology | "any structural anomaly of the firm fibrocartilaginous joint in the median plane between the two opposing surfaces of the pubic bones, which are united by an interpubic disc of fibrocartilage as well as the superior and arcuate pubic ligaments" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0009584 | decreased keratinocyte proliferation | "reduction in the expansion rate of keratinocytes by cell division" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: Not Specified
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| MP:0009614 | absent epidermis stratum spinosum | "absence of the layer of polyhedral cells in the epidermis; shrinkage and adhesion of these cells gives a spiny or prickly appearance" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0009655 | abnormal secondary palate development | "any anomaly in the formation of the part of the palate that is formed during embryonic development when palatal projections from the inner part of the maxillary processes emerge, extend and elevate into a horizontal position above the tongue" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:16942766] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0009736 | abnormal prostate gland branching morphogenesis | "anomaly of the prostatic bud to repeatedly divide into lobules during development of the prostate gland" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0010116 | abnormal primitive urogenital sinus morphology | "any structural anomaly of the ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0010146 | umbilical hernia | "an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the umbilicus; occurs when the muscle through which blood vessels pass to feed the developing fetus fails to completely close" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", PMID:20333300] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0010787 | gastric cysts | "abnormal membranous sacs in the wall of the stomach" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
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| MP:0010942 | abnormal respiratory epithelium morphology | "any structural anomaly of the pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trp63tm1Fmc/Trp63tm1Fmc
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Brd/Trp63tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Trp63tm1Sin/Trp63tm1Sin
Genetic Background: Not Specified
Allelic Composition: Trp63tm1Cmis/Trp63+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Trp63tm2.2Elrf/Trp63tm2.2Elrf
Genetic Background: Not Specified
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| MP:0011091 | complete prenatal lethality | "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Trp63m1Mhda/Trp63m1Mhda
Genetic Background: C3HeB/FeJ-Trp63m1Mhda
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| MP:0011102 | partial embryonic lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith] |
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Allelic Composition: Trp63tm1.1Elrf/Trp63tm1.1Elrf
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0011160 | dermal-epidermal separation | "the appearance of gaps or clefts in the normally continuous junctional interface between the dermis and epidermis" [MGI:csmith] |
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Allelic Composition: Trp63tm2.2Elrf/Trp63tm2.2Elrf
Genetic Background: Not Specified
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| MP:0011774 | abnormal urinary bladder detrusor smooth muscle morphology | "any structural anomaly of the bundles of smooth muscle fibers forming the muscular wall of the urinary bladder, which are arranged in a longitudinal and a circular layer and, on contraction, serve to expel urine" [MGI:anna] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0012062 | small tail bud | "decreased size or area of the primordial region of the embryo that arises to form the tail of the adult" [MGI:anna] |
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Allelic Composition: Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0012067 | abnormal olfactory gland morphology | "any structural anomaly of the Bowman s glands (aka glands of Bowman, olfactory glands), situated in the olfactory mucosa, beneath the olfactory epithelium, in the lamina propria, a connective tissue also containing fibroblasts, blood vessels, and bundles of fine axons from the olfactory neurons; Bowman s glands consists of an acinus in the lamina propria and a secretory duct going out through the olfactory epithelium" [UBERON:0002232] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: B6.129S7-Trp63tm2Brd/J
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| MP:0012069 | abnormal horizontal basal cell morphology | "any structural anomaly of the flat or angular epithelial cell with condensed nuclei and darkly staining cytoplasm containing numerous intermediate filaments inserted into desmosomes contacting surrounding supporting cells, that lie in contact with the basal lamina of olfactory epithelium" [CL:0002184] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: B6.129S7-Trp63tm2Brd/J
Allelic Composition: Trp63tm2Brd/Trp63+
Genetic Background: B6.129S7-Trp63tm2Brd/J
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| MP:0013282 | urinary bladder exstrophy | "a herniation of the urinary bladder through an anterior abdominal wall defect; refers to congenital absence of a portion of the lower anterior abdominal wall and the anterior urinary bladder wall, with eversion of the posterior bladder wall through the defect, an open pubic arch, and widely separated ischia connected by a fibrous band" [http://medical-dictionary.thefreedictionary.com/exstrophy+of+the+bladder, MGI:anna, PMID:17079275] |
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Allelic Composition: Trp63tm2Brd/Trp63tm2Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0013537 | increased salivary gland adenoma incidence | "greater than the expected number of a benign epithelial neoplasm with a glandular organization arising in any salivary gland, occurring in a specific population in a given time period " [MGI:Anna] |
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Allelic Composition: Trp63tm1Fmc/Trp63+,Trp73tm1Fmc/Trp73+
Genetic Background: involves: 129S4/SvJae * C57BL/6
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