ENSMUSG00000026283


Mus musculus

Features
Gene ID: ENSMUSG00000026283
  
Biological name :Ing5
  
Synonyms : Ing5 / Inhibitor of growth protein 5 / Q9D8Y8
  
Possible biological names infered from orthology : inhibitor of growth family member 5 / Q8WYH8
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: D
Gene start: 93803965
Gene end: 93822101
  
Corresponding Affymetrix probe sets: 10348879 (MoGene1.0st)   1431134_at (Mouse Genome 430 2.0 Array)   1436069_at (Mouse Genome 430 2.0 Array)   1442094_at (Mouse Genome 430 2.0 Array)   1454235_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140739
Ensembl peptide - ENSMUSP00000027505
Ensembl peptide - ENSMUSP00000140498
NCBI entrez gene - 66262     See in Manteia.
MGI - MGI:1922816
RefSeq - NM_025454
RefSeq - XM_006529792
RefSeq Peptide - NP_079730
swissprot - A0A087WRR4
swissprot - Q9D8Y8
Ensembl - ENSMUSG00000026283
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ing5aENSDARG00000022413Danio rerio
 ing5bENSDARG00000068175Danio rerio
 ING5ENSGALG00000006317Gallus gallus
 ING5ENSG00000168395Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ing4 / Q8C0D7 / Inhibitor of growth protein 4 / Q9UNL4* / inhibitor of growth family member 4*ENSMUSG0000003033071
Ing1 / Q9QXV3 / Inhibitor of growth protein 1 / Q9UK53* / inhibitor of growth family member 1*ENSMUSG0000004596940
Ing2 / Q9ESK4 / Inhibitor of growth protein 2 / Q9H160* / inhibitor of growth family member 2*ENSMUSG0000006304938
Ing3 / Q8VEK6 / Inhibitor of growth protein 3 / Q9NXR8* / inhibitor of growth family member 3*ENSMUSG0000002967036


Protein motifs (from Interpro)
Interpro ID Name
 IPR001965  Zinc finger, PHD-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR024610  Inhibitor of growth protein, N-terminal histone-binding
 IPR028638  Inhibitor of growth protein 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication ISO
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006473 protein acetylation ISO
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0043966 histone H3 acetylation ISS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0045926 negative regulation of growth ISO
 biological_processGO:2001235 positive regulation of apoptotic signaling pathway IGI
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0070776 MOZ/MORF histone acetyltransferase complex ISS
 molecular_functionGO:0003682 chromatin binding IGI
 molecular_functionGO:0035064 methylated histone binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
HATs acetylate histones
Regulation of TP53 Activity through Acetylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000001729 Akt1 / P31750 / Mus musculus thymoma viral proto-onco 1 (Akt1), transcript variant 3, mRNA. / P31749* / AKT serine/threonine kinase 1*  / reaction
 ENSMUSG00000059552 Trp53 / P02340 / transformation related protein 53 / TP53* / P04637* / tumor protein p53*  / reaction / complex
 ENSMUSG00000038909 Kat7 / Q5SVQ0 / K(lysine) acetyltransferase 7 / O95251* / lysine acetyltransferase 7*  / complex
 ENSMUSG00000028863 Meaf6 / Q2VPQ9 / MYST/Esa1-associated factor 6 / Q9HAF1*  / complex
 ENSMUSG00000026283 Ing5 / Q9D8Y8 / Inhibitor of growth protein 5 / Q8WYH8* / inhibitor of growth family member 5*  / complex
 ENSMUSG00000099517 P68433 / Hist1h3g / Histone H3.1   / reaction
 ENSMUSG00000025764 Jade1 / Q6ZPI0 / Protein Jade-1 / Q6IE81* / jade family PHD finger 1*  / complex
 ENSMUSG00000031540 Kat6a / lysine acetyltransferase 6A / Q92794*  / complex
 ENSMUSG00000021767 Kat6b / Q8BRB7 / Histone acetyltransferase KAT6B / Q8WYB5* / lysine acetyltransferase 6B*  / complex
 ENSMUSG00000036986 Pml / Q60953 / Protein PML / P29590* / promyelocytic leukemia*  / complex / reaction
 ENSMUSG00000001632 Brpf1 / B2RRD7 / Peregrin / P55201* / bromodomain and PHD finger containing 1*  / complex






 

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