ENSMUSG00000025764


Mus musculus

Features
Gene ID: ENSMUSG00000025764
  
Biological name :Jade1
  
Synonyms : Jade1 / Protein Jade-1 / Q6ZPI0
  
Possible biological names infered from orthology : jade family PHD finger 1 / Q6IE81
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: B
Gene start: 41555731
Gene end: 41616864
  
Corresponding Affymetrix probe sets: 10491860 (MoGene1.0st)   1426752_at (Mouse Genome 430 2.0 Array)   1426753_at (Mouse Genome 430 2.0 Array)   1438412_at (Mouse Genome 430 2.0 Array)   1452179_at (Mouse Genome 430 2.0 Array)   1452180_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000141499
Ensembl peptide - ENSMUSP00000142142
Ensembl peptide - ENSMUSP00000141711
Ensembl peptide - ENSMUSP00000141670
Ensembl peptide - ENSMUSP00000026865
Ensembl peptide - ENSMUSP00000127113
Ensembl peptide - ENSMUSP00000128152
Ensembl peptide - ENSMUSP00000131441
NCBI entrez gene - 269424     See in Manteia.
MGI - MGI:1925835
RefSeq - XM_006500784
RefSeq - NM_001130184
RefSeq - NM_001130185
RefSeq - NM_001130186
RefSeq - NM_172303
RefSeq Peptide - NP_001123656
RefSeq Peptide - NP_001123657
RefSeq Peptide - NP_001123658
RefSeq Peptide - NP_758507
swissprot - A0A0A6YWS2
swissprot - A0A0A6YXU2
swissprot - Q6ZPI0
swissprot - A0A0A6YWV0
Ensembl - ENSMUSG00000025764
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 jade1ENSDARG00000033707Danio rerio
 JADE1ENSGALG00000010214Gallus gallus
 JADE1ENSG00000077684Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Jade2 / Q6ZQF7 / Mus musculus jade family PHD finger 2 (Jade2), transcript variant 1, mRNA. / Q9NQC1* / jade family PHD finger 2*ENSMUSG0000002038750
Jade3 / Q6IE82 / Protein Jade-3 / Q92613* / jade family PHD finger 3*ENSMUSG0000003731542
Brd1 / bromodomain containing 1 / O95696*ENSMUSG0000002238722
Brpf3 / bromodomain and PHD finger containing, 3 / Q9ULD4*ENSMUSG0000006395222
Brpf1 / B2RRD7 / Peregrin / P55201* / bromodomain and PHD finger containing 1*ENSMUSG0000000163220
Mllt10 / O54826 / myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 / P55197* / MLLT10, histone lysine methyltransferase DOT1L cofactor*ENSMUSG0000002674317
Mllt6 / MLLT6, PHD finger containingENSMUSG0000003843717
Phf14 / Q9D4H9 / PHD finger protein 14 / O94880*ENSMUSG0000002962916


Protein motifs (from Interpro)
Interpro ID Name
 IPR001965  Zinc finger, PHD-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019542  Enhancer of polycomb-like, N-terminal
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR034732  Extended PHD (ePHD) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0043966 histone H3 acetylation ISS
 biological_processGO:0043981 histone H4-K5 acetylation ISO
 biological_processGO:0043982 histone H4-K8 acetylation ISO
 biological_processGO:0043983 histone H4-K12 acetylation ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway ISO
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle ISO
 cellular_componentGO:0000123 histone acetyltransferase complex ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0036064 ciliary basal body ISO
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
HATs acetylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Ubr2tm1Ytkw/Ubr2tm1Ytkw
Genetic Background: involves: 129S1/Sv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026283 Ing5 / Q9D8Y8 / Inhibitor of growth protein 5 / Q8WYH8* / inhibitor of growth family member 5*  / complex
 ENSMUSG00000099517 P68433 / Hist1h3g / Histone H3.1   / reaction
 ENSMUSG00000028863 Meaf6 / Q2VPQ9 / MYST/Esa1-associated factor 6 / Q9HAF1*  / complex
 ENSMUSG00000038909 Kat7 / Q5SVQ0 / K(lysine) acetyltransferase 7 / O95251* / lysine acetyltransferase 7*  / complex
 ENSMUSG00000030330 Ing4 / Q8C0D7 / Inhibitor of growth protein 4 / Q9UNL4* / inhibitor of growth family member 4*  / complex






 

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