ENSMUSG00000029629


Mus musculus

Features
Gene ID: ENSMUSG00000029629
  
Biological name :Phf14
  
Synonyms : PHD finger protein 14 / Phf14 / Q9D4H9
  
Possible biological names infered from orthology : O94880
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: A1
Gene start: 11907809
Gene end: 12081205
  
Corresponding Affymetrix probe sets: 10536407 (MoGene1.0st)   1420283_at (Mouse Genome 430 2.0 Array)   1440247_at (Mouse Genome 430 2.0 Array)   1446642_at (Mouse Genome 430 2.0 Array)   1453270_a_at (Mouse Genome 430 2.0 Array)   1453271_at (Mouse Genome 430 2.0 Array)   1453743_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000144981
Ensembl peptide - ENSMUSP00000115485
Ensembl peptide - ENSMUSP00000145355
Ensembl peptide - ENSMUSP00000145527
Ensembl peptide - ENSMUSP00000088126
Ensembl peptide - ENSMUSP00000111172
Ensembl peptide - ENSMUSP00000111173
NCBI entrez gene - 75725     See in Manteia.
MGI - MGI:1923539
RefSeq - XM_017321821
RefSeq - XM_006505198
RefSeq - XM_006505199
RefSeq - XM_006505200
RefSeq - XM_006505201
RefSeq - XM_006505202
RefSeq - XM_011241085
RefSeq - XM_017321819
RefSeq - XM_017321820
RefSeq - NM_001168382
RefSeq - NM_029404
RefSeq - XM_006505196
RefSeq - XM_006505197
RefSeq Peptide - NP_001161854
RefSeq Peptide - NP_083680
swissprot - G5E8S0
swissprot - A0A0N4SW36
swissprot - A0A0N4SWI1
swissprot - A0A0N4SV73
swissprot - Q9D4H9
swissprot - F6TN92
Ensembl - ENSMUSG00000029629
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phf14ENSDARG00000061458Danio rerio
 PHF14ENSGALG00000038041Gallus gallus
 PHF14ENSG00000106443Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Brpf3 / bromodomain and PHD finger containing, 3 / Q9ULD4*ENSMUSG0000006395218
Brd1 / bromodomain containing 1 / O95696*ENSMUSG0000002238717
Brpf1 / B2RRD7 / Peregrin / P55201* / bromodomain and PHD finger containing 1*ENSMUSG0000000163217
Jade2 / Q6ZQF7 / Mus musculus jade family PHD finger 2 (Jade2), transcript variant 1, mRNA. / Q9NQC1* / jade family PHD finger 2*ENSMUSG0000002038714
Jade3 / Q6IE82 / Protein Jade-3 / Q92613* / jade family PHD finger 3*ENSMUSG0000003731514
Jade1 / Q6ZPI0 / Protein Jade-1 / Q6IE81* / jade family PHD finger 1*ENSMUSG0000002576414
Mllt10 / O54826 / myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 / P55197* / MLLT10, histone lysine methyltransferase DOT1L cofactor*ENSMUSG0000002674313
Mllt6 / MLLT6, PHD finger containingENSMUSG0000003843711


Protein motifs (from Interpro)
Interpro ID Name
 IPR001965  Zinc finger, PHD-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR034732  Extended PHD (ePHD) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0048286 lung alveolus development IMP
 biological_processGO:0072201 negative regulation of mesenchymal cell proliferation IMP
 biological_processGO:2000584 negative regulation of platelet-derived growth factor receptor-alpha signaling pathway IMP
 biological_processGO:2000791 negative regulation of mesenchymal cell proliferation involved in lung development IMP
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000351 increased cell proliferation "greater than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Col2a1/Acan-rtTA,tetO-cre)#Vlf/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001575 cyanosis "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159]
Show

Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Col2a1/Acan-rtTA,tetO-cre)#Vlf/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001953 respiratory failure "cessation of or failure to commence breathing" [MGI:cls, J:60159]
Show

Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Col2a1/Acan-rtTA,tetO-cre)#Vlf/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001954 respiratory distress "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
Show

Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Col2a1/Acan-rtTA,tetO-cre)#Vlf/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008277 abnormal sternum ossification "anomaly in the process of the formation of the sternum bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958, MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Col2a1/Acan-rtTA,tetO-cre)#Vlf/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010903 abnormal pulmonary alveolus wall morphology 
Show

Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Col2a1/Acan-rtTA,tetO-cre)#Vlf/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Col2a1/Acan-rtTA,tetO-cre)#Vlf/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011703 increased fibroblast proliferation "greater the expansion rate of a fibroblast cell population by cell division" [MGI:csmith]
Show

Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Tg(Col2a1/Acan-rtTA,tetO-cre)#Vlf/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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