ENSMUSG00000063952


Mus musculus

Features
Gene ID: ENSMUSG00000063952
  
Biological name :Brpf3
  
Synonyms : bromodomain and PHD finger containing, 3 / Brpf3
  
Possible biological names infered from orthology : Q9ULD4
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: A3.3
Gene start: 28801090
Gene end: 28838546
  
Corresponding Affymetrix probe sets: 10443421 (MoGene1.0st)   1435225_s_at (Mouse Genome 430 2.0 Array)   1455243_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000004985
NCBI entrez gene - 268936     See in Manteia.
MGI - MGI:2146836
RefSeq - XM_017317484
RefSeq - NM_001081315
RefSeq - XM_006524332
RefSeq - XM_017317483
RefSeq - XM_006524326
RefSeq - XM_006524328
RefSeq - XM_006524329
RefSeq - XM_006524330
RefSeq Peptide - NP_001074784
swissprot - B2KF05
Ensembl - ENSMUSG00000063952
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 brpf3aENSDARG00000070513Danio rerio
 brpf3bENSDARG00000074238Danio rerio
 BRPF3ENSGALG00000000776Gallus gallus
 BRPF3ENSG00000096070Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Brd1 / bromodomain containing 1 / O95696*ENSMUSG0000002238753
Brpf1 / B2RRD7 / Peregrin / P55201* / bromodomain and PHD finger containing 1*ENSMUSG0000000163250
Jade3 / Q6IE82 / Protein Jade-3 / Q92613* / jade family PHD finger 3*ENSMUSG0000003731516
Jade1 / Q6ZPI0 / Protein Jade-1 / Q6IE81* / jade family PHD finger 1*ENSMUSG0000002576415
Mllt6 / MLLT6, PHD finger containingENSMUSG0000003843715
Mllt10 / O54826 / myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 / P55197* / MLLT10, histone lysine methyltransferase DOT1L cofactor*ENSMUSG0000002674314
Jade2 / Q6ZQF7 / Mus musculus jade family PHD finger 2 (Jade2), transcript variant 1, mRNA. / Q9NQC1* / jade family PHD finger 2*ENSMUSG0000002038714
Phf14 / Q9D4H9 / PHD finger protein 14 / O94880*ENSMUSG0000002962914


Protein motifs (from Interpro)
Interpro ID Name
 IPR000313  PWWP domain
 IPR001487  Bromodomain
 IPR001965  Zinc finger, PHD-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018359  Bromodomain, conserved site
 IPR019542  Enhancer of polycomb-like, N-terminal
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR034732  Extended PHD (ePHD) domain
 IPR035502  BR140-related, PWWD domain
 IPR036427  Bromodomain-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043966 histone H3 acetylation IEA
 cellular_componentGO:0070776 MOZ/MORF histone acetyltransferase complex IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
HATs acetylate histones
Regulation of TP53 Activity through Acetylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Asxl1tm1a(EUCOMM)Wtsi/Asxl1+
Genetic Background: B6Dnk;B6Brd;B6N-Asxl1tm1a(EUCOMM)Wtsi Tyrc-Brd/WtsiH

 MP:0005628 decreased circulating potassium level "less than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [RGD:Rat Genome Database submission]
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Allelic Composition: Asxl1tm1a(EUCOMM)Wtsi/Asxl1+
Genetic Background: B6Dnk;B6Brd;B6N-Asxl1tm1a(EUCOMM)Wtsi Tyrc-Brd/WtsiH

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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