ENSMUSG00000006288


Mus musculus

Features
Gene ID: ENSMUSG00000006288
  
Biological name :Ttc5
  
Synonyms : Q99LG4 / tetratricopeptide repeat domain 5 / Ttc5
  
Possible biological names infered from orthology : Q8N0Z6
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: C1
Gene start: 50765415
Gene end: 50785519
  
Corresponding Affymetrix probe sets: 10419460 (MoGene1.0st)   1424508_at (Mouse Genome 430 2.0 Array)   1460079_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000006451
Ensembl peptide - ENSMUSP00000154085
Ensembl peptide - ENSMUSP00000154412
Ensembl peptide - ENSMUSP00000154731
NCBI entrez gene - 219022     See in Manteia.
MGI - MGI:2683584
RefSeq - XM_006518839
RefSeq - NM_001080949
RefSeq - NM_177625
RefSeq Peptide - NP_808293
RefSeq Peptide - NP_001074418
swissprot - Q8BNN3
swissprot - Q99LG4
Ensembl - ENSMUSG00000006288
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ttc5ENSDARG00000013329Danio rerio
 TTC5ENSG00000136319Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR032076  Tetratricopeptide repeat protein 5, OB fold domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IGI
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Methylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000059552 Trp53 / P02340 / transformation related protein 53 / TP53* / P04637* / tumor protein p53*  / complex / reaction
 ENSMUSG00000023110 Prmt5 / protein arginine N-methyltransferase 5 / O14744* / protein arginine methyltransferase 5*  / reaction / complex
 ENSMUSG00000055024 Ep300 / B2RWS6 / Histone acetyltransferase p300 / Q09472* / E1A binding protein p300*  / reaction / complex
 ENSMUSG00000021690 Jmy / junction mediating and regulatory protein, p53 cofactor / Q8N9B5*  / reaction / complex
 ENSMUSG00000029521 Chek2 / Q9Z265 / Serine/threonine-protein kinase Chk2 / O96017* / checkpoint kinase 2*  / reaction
 ENSMUSG00000034218 Atm / Q62388 / Serine-protein kinase ATM / Q13315* / ATM serine/threonine kinase*  / reaction






 

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