ENSDARG00000035559


Danio rerio

Features
Gene ID: ENSDARG00000035559
  
Biological name :tp53
  
Synonyms : P79734 / tp53 / tumor protein p53
  
Possible biological names infered from orthology : P02340 / P04637 / transformation related protein 53 / Trp53
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 24086227
Gene end: 24097805
  
Corresponding Affymetrix probe sets: Dr.2052.1.S1_at (Zebrafish Array)   NM_131327_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000151125
Ensembl peptide - ENSDARP00000152377
Ensembl peptide - ENSDARP00000051548
Ensembl peptide - ENSDARP00000116736
Ensembl peptide - ENSDARP00000144168
NCBI entrez gene - 30590     See in Manteia.
RefSeq - NM_001328587
RefSeq - NM_001271820
RefSeq - NM_001328588
RefSeq - NM_131327
RefSeq - XM_005165101
RefSeq Peptide - NP_001315517
RefSeq Peptide - NP_571402
RefSeq Peptide - NP_001258749
RefSeq Peptide - NP_001315516
swissprot - A0A0B4VFS7
swissprot - B0R0M3
swissprot - G1K2L5
swissprot - P79734
ZFIN ID - ZDB-GENE-990415-270
Ensembl - ENSDARG00000035559
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TP53ENSG00000141510Homo sapiens
 Trp53ENSMUSG00000059552Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tp73 / tumor protein p73 / Trp73* / Q9JJP2* / O15350* / transformation related protein 73*ENSDARG0000001795343
tp63 / tumor protein p63 / Trp63* / Q9H3D4* / O88898* / transformation related protein 63*ENSDARG0000004435642


Protein motifs (from Interpro)
Interpro ID Name
 IPR002117  p53 tumour suppressor family
 IPR008967  p53-like transcription factor, DNA-binding
 IPR010991  p53, tetramerisation domain
 IPR011615  p53, DNA-binding domain
 IPR012346  p53/RUNT-type transcription factor, DNA-binding domain superfamily
 IPR032646  Tumour protein p73


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint IMP
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006914 autophagy IGI
 biological_processGO:0006915 apoptotic process IMP
 biological_processGO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator IMP
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007283 spermatogenesis IGI
 biological_processGO:0009411 response to UV IMP
 biological_processGO:0010165 response to X-ray IMP
 biological_processGO:0010332 response to gamma radiation IBA
 biological_processGO:0010526 negative regulation of transposition, RNA-mediated IMP
 biological_processGO:0016525 negative regulation of angiogenesis IGI
 biological_processGO:0031065 positive regulation of histone deacetylation IBA
 biological_processGO:0031571 mitotic G1 DNA damage checkpoint IBA
 biological_processGO:0031647 regulation of protein stability IGI
 biological_processGO:0034644 cellular response to UV IBA
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0043249 erythrocyte maturation IGI
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
 biological_processGO:0043525 positive regulation of neuron apoptotic process IGI
 biological_processGO:0045786 negative regulation of cell cycle IMP
 biological_processGO:0045787 positive regulation of cell cycle IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0048730 epidermis morphogenesis IMP
 biological_processGO:0048821 erythrocyte development IGI
 biological_processGO:0051262 protein tetramerization IEA
 biological_processGO:0051289 protein homotetramerization IDA
 biological_processGO:0051597 response to methylmercury IDA
 biological_processGO:0051782 negative regulation of cell division IMP
 biological_processGO:0060216 definitive hemopoiesis IGI
 biological_processGO:0060729 intestinal epithelial structure maintenance IGI
 biological_processGO:0061484 hematopoietic stem cell homeostasis IGI
 biological_processGO:0071456 cellular response to hypoxia IMP
 biological_processGO:0090398 cellular senescence IGI
 biological_processGO:0097193 intrinsic apoptotic signaling pathway IMP
 biological_processGO:1902262 apoptotic process involved in blood vessel morphogenesis IMP
 biological_processGO:2000779 regulation of double-strand break repair IMP
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005657 replication fork IBA
 cellular_componentGO:0005667 transcription factor complex IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IBA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0002039 p53 binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IBA
 molecular_functionGO:0003684 damaged DNA binding IBA
 molecular_functionGO:0003690 double-stranded DNA binding IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Oncogene Induced Senescence
DNA Damage/Telomere Stress Induced Senescence
SUMOylation of transcription factors
Autodegradation of the E3 ubiquitin ligase COP1
Ub-specific processing proteases
Ovarian tumor domain proteases
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Regulation of TP53 Expression
Regulation of TP53 Activity through Phosphorylation
Regulation of TP53 Degradation
Regulation of TP53 Activity through Acetylation
Regulation of TP53 Activity through Association with Co-factors
Regulation of TP53 Activity through Methylation
PI5P Regulates TP53 Acetylation
G2/M DNA damage checkpoint
G2/M Checkpoints
Stabilization of p53
Transcriptional activation of cell cycle inhibitor p21
The role of GTSE1 in G2/M progression after G2 checkpoint
RUNX3 regulates CDKN1A transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle cilium decreased length , abnormal
Kupffers vesicle cilium disorganized , abnormal
Kupffers vesicle cilium has fewer parts of type Kupffers vesicle axonemal microtubule, abnormal
Kupffers vesicle cilium decreased amount , abnormal
Kupffers vesicle decreased size , abnormal
Kupffers vesicle altered number of ciliated cell axonemal microtubule, abnormal
Kupffers vesicle axoneme disorganized , abnormal
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 ZFA:0000007 blood blood accumulation heart , abnormal
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 ZFA:0000008 brain brain decreased size , abnormal
brain morphology , abnormal
brain malformed , abnormal
brain shape , abnormal
brain apoptotic , abnormal
brain primary motor neuron spatial pattern , abnormal
brain primary motor neuron decreased amount , abnormal
brain glioma neoplastic , abnormal
brain decreased object quality , abnormal
brain hydrophilic , abnormal
brain hydrocephalic , abnormal
brain branching morphogenesis of a nerve decreased occurrence , abnormal
brain necrotic , abnormal
brain cell apoptotic , abnormal
brain size , ameliorated
brain decreased volume , abnormal
brain hemorrhagic , abnormal
brain vasculature development process quality , abnormal
brain apoptotic process occurrence , ameliorated
brain edematous , abnormal
brain structure , abnormal
brain apoptotic process increased occurrence , abnormal
brain cell death increased occurrence , abnormal
brain medulloblastoma increased amount , abnormal
brain medulloblastoma increased amount , exacerbated
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 ZFA:0000009 cardiac ventricle cardiac ventricle has extra parts of type cardiac muscle cell , abnormal
cardiac ventricle decreased size , abnormal
cardiac ventricle cardiac conduction decreased velocity , abnormal
cardiac ventricle increased distribution , abnormal
cardiac ventricle cardiac muscle cell increased amount , abnormal
cardiac ventricle truncated , abnormal
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 ZFA:0000012 central nervous system central nervous system nucleus apoptotic , abnormal
central nervous system neuron apoptotic , abnormal
central nervous system apoptotic , abnormal
central nervous system necrotic , abnormal
central nervous system cell death increased occurrence , abnormal
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 ZFA:0000014 dorsal aorta dorsal aorta structure , abnormal
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 ZFA:0000019 epiphysis epiphysis apoptotic process increased process quality , abnormal
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 ZFA:0000022 floor plate floor plate increased width , abnormal
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 ZFA:0000024 retinal ganglion cell layer retinal ganglion cell layer immature , abnormal
retinal ganglion cell layer cell proliferation increased occurrence , abnormal
retinal ganglion cell layer decreased thickness , abnormal
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 ZFA:0000029 hindbrain hindbrain morphology , abnormal
hindbrain neuroepithelial cell decreased amount , abnormal
hindbrain neuron decreased amount , abnormal
hindbrain oligodendrocyte decreased amount , abnormal
hindbrain axon decreased amount , abnormal
hindbrain oligodendrocyte development decreased process quality , abnormal
hindbrain oligodendrocyte development process quality , ameliorated
hindbrain oligodendrocyte amount , ameliorated
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 ZFA:0000032 hypothalamus hypothalamus apoptotic process increased process quality , abnormal
hypothalamus absent , abnormal
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 ZFA:0000033 intermediate cell mass of mesoderm intermediate cell mass of mesoderm neutrophil absent , abnormal
intermediate cell mass of mesoderm decreased amount , abnormal
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 ZFA:0000035 lens lens malformed , abnormal
lens protruding , abnormal
lens vacuolated , abnormal
lens morphology , abnormal
lens decreased size , abnormal
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 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
anatomical structure increased amount , abnormal
anatomical structure amount , ameliorated
anatomical structure neurofibrosarcoma increased amount , abnormal
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 ZFA:0000038 margin margin ventral region decreased distribution , abnormal
margin ventral region decreased amount , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary decreased size , abnormal
midbrain hindbrain boundary morphology , abnormal
midbrain hindbrain boundary malformed , abnormal
midbrain hindbrain boundary decreased thickness , abnormal
midbrain hindbrain boundary amorphous , abnormal
midbrain hindbrain boundary decreased amount , abnormal
midbrain hindbrain boundary increased angle to midbrain hindbrain boundary , abnormal
midbrain hindbrain boundary cell increased length , abnormal
midbrain hindbrain boundary posterior region decreased distribution , abnormal
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 ZFA:0000045 neural crest neural crest physical object quality , abnormal
neural crest decreased amount , abnormal
neural crest apoptotic process increased occurrence , abnormal
neural crest cell proliferation decreased occurrence , abnormal
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 ZFA:0000046 retinal neural layer retinal neural layer apical region increased area , abnormal
retinal neural layer structure , abnormal
retinal neural layer cell aggregated , abnormal
retinal neural layer morphology , abnormal
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 ZFA:0000047 peripheral olfactory organ peripheral olfactory organ disorganized , abnormal
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 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
otic vesicle cilium decreased length , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
pericardium edematous , ameliorated
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 ZFA:0000066 proctodeum proctodeum anatomical region unfused from cloacal chamber , abnormal
proctodeum atretic , abnormal
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 ZFA:0000075 spinal cord spinal cord has extra parts of type neuron , abnormal
spinal cord apoptotic , abnormal
spinal cord opaque , abnormal
spinal cord curved , abnormal
spinal cord decreased distribution , abnormal
spinal cord decreased amount , abnormal
spinal cord beta-galactosidase activity increased process quality , abnormal
spinal cord apoptotic process occurrence , ameliorated
spinal cord oligodendrocyte increased amount , abnormal
spinal cord oligodendrocyte decreased amount , abnormal
spinal cord oligodendrocyte amount , ameliorated
spinal cord central nervous system myelination decreased occurrence , abnormal
spinal cord central nervous system myelination occurrence , ameliorated
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 ZFA:0000076 swim bladder swim bladder absent , abnormal
swim bladder hypoplastic , abnormal
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 ZFA:0000077 tail bud tail bud increased size , abnormal
tail bud mitotic cell cycle increased occurrence , abnormal
tail bud immature , abnormal
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 ZFA:0000079 telencephalon telencephalon wholly dorsalized , abnormal
telencephalon neuron decreased amount , abnormal
telencephalon disorganized , abnormal
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 ZFA:0000082 vein vein increased amount , abnormal
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 ZFA:0000083 ventral mesoderm ventral mesoderm mislocalised , abnormal
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 ZFA:0000084 yolk yolk increased size , abnormal
yolk swollen , abnormal
yolk increased volume , abnormal
yolk opaque , abnormal
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 ZFA:0000092 axis axis bent , abnormal
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 ZFA:0000094 blood island blood island increased size , abnormal
blood island hematopoietic stem cell decreased amount , abnormal
blood island hematopoietic stem cell amount , ameliorated
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 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton absent , abnormal
pharyngeal arch 3-7 skeleton decreased size , abnormal
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 ZFA:0000099 brain vasculature brain vasculature broken , abnormal
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 ZFA:0000100 cerebellum cerebellum neoplastic , abnormal
cerebellum neoplasm increased amount , abnormal
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 ZFA:0000101 diencephalon diencephalon has fewer parts of type dopaminergic neuron , abnormal
diencephalon neuron decreased amount , abnormal
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 ZFA:0000105 epidermis epidermis blistered , abnormal
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 ZFA:0000106 extension extension decreased length , abnormal
extension shortened , abnormal
extension decreased thickness , abnormal
extension decreased size , abnormal
extension edematous , abnormal
extension disorganized , abnormal
extension morphology , ameliorated
extension decreased area , ameliorated
extension shape , abnormal
extension increased thickness , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
eye decreased diameter , abnormal
eye morphology , abnormal
eye edematous , abnormal
eye adjacent to eye , abnormal
eye aplastic , abnormal
eye atrophied , abnormal
eye malformed , abnormal
eye neoplastic , abnormal
eye fused with eye , abnormal
eye sarcoma present , abnormal
eye size , ameliorated
eye decreased width , abnormal
eye anatomical region neoplastic , exacerbated
eye neurofibrosarcoma increased amount , exacerbated
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 ZFA:0000108 fin fin malformed , abnormal
fin kinked , abnormal
fin decreased size , abnormal
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 ZFA:0000109 forebrain forebrain ventral region absent , abnormal
forebrain apoptotic , abnormal
forebrain medial region aplastic , abnormal
forebrain morphology , abnormal
forebrain increased size , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle increased size , abnormal
fourth ventricle decreased size , abnormal
fourth ventricle edematous , abnormal
fourth ventricle decreased volume , abnormal
fourth ventricle morphology , abnormal
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 ZFA:0000112 gut gut neoplastic , abnormal
gut position , abnormal
gut size , ameliorated
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 ZFA:0000114 heart heart edematous , abnormal
heart hypoplastic , abnormal
heart malformed , abnormal
heart deformed , abnormal
heart increased size , abnormal
heart has extra parts of type cardiac muscle cell , abnormal
heart decreased object quality , abnormal
heart morphology , abnormal
heart mislocalised radially , abnormal
heart linear , abnormal
heart has fewer parts of type cardiac muscle cell , abnormal
heart dilated , abnormal
heart displaced to whole organism right side, abnormal
heart displaced to whole organism medial side, abnormal
heart decreased size , abnormal
heart malformed , ameliorated
heart decreased functionality , abnormal
heart lateralized , abnormal
heart nucleate erythrocyte amount , ameliorated
heart Z disc disorganized , abnormal
heart cardiac myofibril disorganized , abnormal
heart physical object quality , abnormal
heart decreased amount , abnormal
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 ZFA:0000119 retinal inner nuclear layer retinal inner nuclear layer has fewer parts of type amacrine cell , abnormal
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 ZFA:0000123 liver liver hyperplastic , abnormal
liver position , abnormal
liver inverted , abnormal
liver hepatic tumor increased occurrence , abnormal
liver spindle cell sarcoma increased occurrence , abnormal
liver hepatocellular carcinoma present , abnormal
liver neoplastic , abnormal
liver apoptotic process increased process quality , abnormal
liver inflammatory , abnormal
liver apoptotic process increased occurrence , abnormal
liver spatial pattern , ameliorated
liver size , ameliorated
liver increased amount , abnormal
liver hepatocellular carcinoma increased object quality , abnormal
liver amount , ameliorated
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 ZFA:0000128 midbrain midbrain elongated , abnormal
midbrain morphology , abnormal
midbrain apoptotic , abnormal
midbrain increased amount , abnormal
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 ZFA:0000132 neural plate neural plate dorsal region apoptotic , abnormal
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 ZFA:0000135 notochord notochord curved , abnormal
notochord bent , abnormal
notochord undulate , abnormal
notochord deformed , abnormal
notochord mislocalised laterally , abnormal
notochord degenerate , abnormal
notochord kinked , abnormal
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 ZFA:0000140 pancreas pancreas hypoplastic , abnormal
pancreas position , abnormal
pancreas inverted , abnormal
pancreas decreased size , abnormal
pancreas decreased amount , abnormal
pancreas Acinar adenocarcinoma present , abnormal
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 ZFA:0000142 peripheral nervous system peripheral nervous system neoplastic, malignant , abnormal
peripheral nervous system neurofibrosarcoma increased amount , abnormal
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 ZFA:0000144 retinal pigmented epithelium retinal pigmented epithelium broken , abnormal
retinal pigmented epithelium decreased amount , abnormal
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 ZFA:0000150 pronephric duct pronephric duct cystic , abnormal
pronephric duct dilated , abnormal
pronephric duct cilium disoriented , abnormal
pronephric duct decreased length , abnormal
pronephric duct structure , abnormal
pronephric duct cilium decreased length , abnormal
pronephric duct cilium curved , abnormal
pronephric duct malformed , abnormal
pronephric duct single ciliated epithelial cell decreased amount , abnormal
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 ZFA:0000151 pronephros pronephros cystic , abnormal
pronephros lacks all parts of type corpuscles of Stannius , abnormal
pronephros lacks all parts of type pronephric proximal straight tubule , abnormal
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 ZFA:0000152 retina retina morphology , abnormal
retina has fewer parts of type amacrine cell , abnormal
retina proliferative region increased size , abnormal
retina lacks all parts of type amacrine cell , abnormal
retina disorganized , abnormal
retina adherens junction increased size , abnormal
retina adherens junction distributed , abnormal
retina cell disorganized , abnormal
retina malformed , abnormal
retina decreased size , abnormal
retina cell proliferation decreased process quality , abnormal
retina protruding into brain , abnormal
retina apoptotic process increased process quality , abnormal
retina structure , abnormal
retina cell decreased amount , abnormal
retina apoptotic , abnormal
retina mitotic cell cycle increased occurrence , abnormal
retina degeneration , abnormal
retina dopaminergic neuron decreased amount , abnormal
retina apoptotic process increased occurrence , abnormal
retina absent , abnormal
retina apoptotic process process quality , ameliorated
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 ZFA:0000155 somite somite shape , abnormal
somite morphology , abnormal
somite decreased size , abnormal
somite decreased amount , abnormal
somite filamentous actin deformed , abnormal
somite condensed , abnormal
somite deformed , abnormal
somite fused with somite , abnormal
somite U-shaped , abnormal
somite apoptotic , abnormal
somite malformed , abnormal
somite muscle pioneer absent , abnormal
somite actin filament disorganized , abnormal
somite actin filament decondensed , abnormal
somite focal adhesion decreased amount , abnormal
somite posterior-most region decreased amount , abnormal
somite cuboid , abnormal
somite decreased width , abnormal
somite slow muscle cell morphology , abnormal
somite slow muscle cell undulate , abnormal
somite fast muscle cell morphology , abnormal
somite increased size , abnormal
somite shape , ameliorated
somite posterior side spatial pattern , ameliorated
somite increased amount , abnormal
somite increased distribution , abnormal
somite lateral region decreased amount , abnormal
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 ZFA:0000159 tectal ventricle tectal ventricle decreased volume , abnormal
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 ZFA:0000161 third ventricle third ventricle increased size , abnormal
third ventricle decreased size , abnormal
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 ZFA:0000172 branchial muscle branchial muscle malformed , abnormal
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 ZFA:0000184 cleithrum cleithrum absent , abnormal
cleithrum malformed , abnormal
cleithrum decreased distribution , abnormal
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 ZFA:0000186 common cardinal vein common cardinal vein malformed , abnormal
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 ZFA:0000200 dorsal root ganglion dorsal root ganglion neuron decreased amount , abnormal
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 ZFA:0000217 inner ear inner ear has extra parts of type otolith , abnormal
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 ZFA:0000228 lateral line primordium lateral line primordium decreased size , abnormal
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 ZFA:0000236 mandibular muscle mandibular muscle morphology , abnormal
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 ZFA:0000242 male organism male organism sterile , abnormal
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 ZFA:0000243 neuromast neuromast increased distance neuromast , abnormal
neuromast decreased amount , abnormal
neuromast spatial pattern , abnormal
neuromast hair cell decreased amount , abnormal
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 ZFA:0000247 cranial nerve VIII cranial nerve VIII defasciculated , abnormal
cranial nerve VIII axon guidance process quality , abnormal
cranial nerve VIII axon mislocalised , abnormal
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 ZFA:0000250 opercle opercle intramembranous ossification decreased process quality , abnormal
opercle decreased distribution , abnormal
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 ZFA:0000255 paraxial mesoderm paraxial mesoderm increased amount , abnormal
paraxial mesoderm increased distribution , abnormal
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 ZFA:0000279 segmental plate segmental plate increased distribution , abnormal
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 ZFA:0000295 trigeminal ganglion trigeminal ganglion axon decreased length , abnormal
trigeminal ganglion axon branchiness , abnormal
trigeminal ganglion axon arborization disrupted , abnormal
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 ZFA:0000297 vagal lobe vagal lobe motor neuron decreased amount , abnormal
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 ZFA:0000301 medial rectus medial rectus myofibril disorganized , abnormal
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 ZFA:0000303 female organism female organism absent , abnormal
female organism sterile , abnormal
female organism present , ameliorated
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 ZFA:0000328 cephalic musculature cephalic musculature decreased amount , abnormal
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 ZFA:0000330 cloacal chamber cloacal chamber distended , abnormal
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 ZFA:0000339 digestive system digestive system hepatocellular carcinoma increased amount , abnormal
digestive system spindle cell sarcoma present , abnormal
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 ZFA:0000354 gill gill neoplastic , abnormal
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 ZFA:0000360 heart tube heart tube left side of axis , abnormal
heart tube centered , abnormal
heart tube decreased length , abnormal
heart tube inverted , abnormal
heart tube symmetry , abnormal
heart tube straight , abnormal
heart tube morphology , abnormal
heart tube cardiac muscle cell size , abnormal
heart tube cardiac muscle cell structure , abnormal
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 ZFA:0000368 integument integument rough , abnormal
integument melanoma increased amount , abnormal
integument neoplastic , abnormal
integument increased amount , abnormal
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 ZFA:0000387 motor nucleus of vagal nerve motor nucleus of vagal nerve anatomical region decreased size , abnormal
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 ZFA:0000396 nervous system nervous system wholly anterioralized , abnormal
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 ZFA:0000402 olfactory bulb olfactory bulb disorganized , abnormal
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 ZFA:0000403 ovary ovary neoplastic , abnormal
ovary apoptotic process occurrence , ameliorated
ovary apoptotic process increased occurrence , abnormal
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 ZFA:0000414 presumptive cephalic mesoderm presumptive cephalic mesoderm gene expression disrupted , abnormal
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 ZFA:0000418 pretectum pretectum dopaminergic neuron decreased amount , abnormal
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 ZFA:0000435 cranial nerve II cranial nerve II hypoplastic , abnormal
cranial nerve II decreased thickness , abnormal
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 ZFA:0000445 optic tectum optic tectum increased size , abnormal
optic tectum decreased size , abnormal
optic tectum neuron decreased amount , abnormal
optic tectum structure , abnormal
optic tectum regulation of neuronal action potential disrupted , abnormal
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 ZFA:0000470 preoptic area preoptic area morphology , abnormal
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 ZFA:0000471 atrium atrium has extra parts of type cardiac muscle cell , abnormal
atrium orientation cardiac ventricle , abnormal
atrium inverted , abnormal
atrium cardiac conduction decreased velocity , abnormal
atrium cardiac muscle cell increased amount , abnormal
atrium elongated , abnormal
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 ZFA:0000473 trunk musculature trunk musculature striated muscle cell decreased amount , abnormal
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 ZFA:0000475 paraventricular organ paraventricular organ neurotransmitter metabolic process absent , abnormal
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 ZFA:0000476 branchiostegal ray branchiostegal ray intramembranous ossification decreased process quality , abnormal
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 ZFA:0000477 posterior cardinal vein posterior cardinal vein structure , abnormal
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 ZFA:0000505 dorsal telencephalon dorsal telencephalon morphology , abnormal
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 ZFA:0000511 extraocular musculature extraocular musculature decreased amount , abnormal
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 ZFA:0000529 kidney kidney increased amount , abnormal
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 ZFA:0000545 medulla oblongata medulla oblongata neoplastic , abnormal
medulla oblongata neoplasm increased amount , abnormal
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 ZFA:0000547 mouth mouth open , abnormal
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 ZFA:0000556 optic chiasm optic chiasm glioma neoplastic , abnormal
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 ZFA:0000561 parasphenoid parasphenoid intramembranous ossification decreased process quality , abnormal
parasphenoid decreased distribution , abnormal
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 ZFA:0000578 ceratohyal bone ceratohyal bone mislocalised , abnormal
ceratohyal bone perichondral ossification decreased process quality , abnormal
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 ZFA:0000598 testis testis degenerate , abnormal
testis sperm decreased amount , abnormal
testis neoplastic , abnormal
testis oocyte present , abnormal
testis spermatid absent , abnormal
testis sperm absent , abnormal
testis germ line cell increased size , abnormal
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 ZFA:0000610 vertical myoseptum vertical myoseptum U-shaped , abnormal
vertical myoseptum structure , abnormal
vertical myoseptum decreased length , abnormal
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 ZFA:0000640 cornea cornea increased thickness , abnormal
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 ZFA:0000664 cranial nerve VII cranial nerve VII shape , abnormal
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 ZFA:0000669 head kidney head kidney hematopoietic stem cell proliferation rate , ameliorated
head kidney hematopoietic stem cell amount , ameliorated
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 ZFA:0000672 hyomandibula hyomandibula perichondral ossification decreased process quality , abnormal
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 ZFA:0000697 cranial nerve V cranial nerve V decreased size , abnormal
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 ZFA:0000706 posterior intestine posterior intestine neoplastic , abnormal
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 ZFA:0000737 cranium cranium malformed , abnormal
cranium apoptotic process process quality , ameliorated
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 ZFA:0000816 oral epithelium oral epithelium epithelial cell morphology , abnormal
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 ZFA:0000818 vagal neural crest vagal neural crest decreased size , abnormal
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 ZFA:0000823 rhombomere 5 rhombomere 5 neuron decreased amount , abnormal
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 ZFA:0000863 dermatocranium dermatocranium ossification delayed , abnormal
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 ZFA:0000940 posterior lateral line neuromast posterior lateral line neuromast decreased amount , abnormal
posterior lateral line neuromast mislocalised , abnormal
posterior lateral line neuromast irregular spatial pattern , abnormal
posterior lateral line neuromast far from posterior lateral line neuromast , abnormal
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 ZFA:0000943 pectoral fin skeleton pectoral fin skeleton decreased size , abnormal
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 ZFA:0000944 posterior lateral line posterior lateral line has fewer parts of type posterior lateral line neuromast , abnormal
posterior lateral line increased diameter , abnormal
posterior lateral line axon defasciculated , abnormal
posterior lateral line decreased length , abnormal
posterior lateral line myelinating Schwann cell circular , abnormal
posterior lateral line neuromast hair cell apoptotic , abnormal
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 ZFA:0000948 rhombomere 3 rhombomere 3 neuron increased amount , abnormal
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 ZFA:0001027 oral cavity oral cavity decreased size , abnormal
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 ZFA:0001055 pronephric duct opening pronephric duct opening closed , abnormal
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 ZFA:0001056 myotome myotome U-shaped , abnormal
myotome muscle tendon junction malformed , abnormal
myotome muscle tendon junction U-shaped , abnormal
myotome muscle cell increased length , abnormal
myotome decreased size , abnormal
myotome decreased width , abnormal
myotome width , ameliorated
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 ZFA:0001058 caudal fin caudal fin curved ventral , abnormal
caudal fin curved , abnormal
caudal fin decreased thickness , abnormal
caudal fin apoptotic process increased process quality , abnormal
caudal fin deformed , abnormal
caudal fin hypoplastic , abnormal
caudal fin blistered , abnormal
caudal fin atrophied , abnormal
caudal fin epidermis apoptotic , abnormal
caudal fin morphology , abnormal
caudal fin truncated , abnormal
caudal fin kinked , abnormal
caudal fin absent , abnormal
caudal fin posterior region absent , abnormal
caudal fin ventral region absent , abnormal
Show

 ZFA:0001064 rhombomere rhombomere pattern specification process occurrence , abnormal
rhombomere neuron differentiation increased occurrence , abnormal
Show

 ZFA:0001069 ventral fin fold ventral fin fold absent , abnormal
Show

 ZFA:0001078 thymus thymus neoplasm increased occurrence , abnormal
thymus decreased amount , abnormal
thymus amount , ameliorated
Show

 ZFA:0001080 sclerotome sclerotome structure , abnormal
Show

 ZFA:0001083 ventricular zone ventricular zone cell apoptotic , abnormal
Show

 ZFA:0001086 muscle pioneer muscle pioneer increased amount , abnormal
Show

 ZFA:0001089 myoseptum myoseptum partially broken , abnormal
myoseptum decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism anterior-posterior axis decreased length , abnormal
whole organism anterior-posterior axis curved , abnormal
whole organism apoptotic , abnormal
whole organism decreased sensitivity to irradiation , abnormal
whole organism edematous , abnormal
whole organism morphology , abnormal
whole organism wholly dorsalized , abnormal
whole organism anterior-posterior axis increased curvature , abnormal
whole organism neurofibroma increased amount , abnormal
whole organism neoplasm increased occurrence , abnormal
whole organism curved ventral , abnormal
whole organism dead , abnormal
whole organism semi-viable , abnormal
whole organism anterior-posterior axis shortened , abnormal
whole organism physical object quality , abnormal
whole organism curved , abnormal
whole organism increased curvature , abnormal
whole organism melanoma neoplastic, invasive , abnormal
whole organism neoplastic , abnormal
whole organism sarcoma increased object quality , abnormal
whole organism decreased pigmentation , abnormal
whole organism anatomical axis asymmetrical , abnormal
whole organism anterior-posterior axis curved ventral , abnormal
whole organism nephroblastoma increased object quality , abnormal
whole organism lacks all parts of type pharyngeal arch cartilage , abnormal
whole organism lacks all parts of type dorsal root ganglion , abnormal
whole organism lacks all parts of type enteric nervous system neuron, abnormal
whole organism ploidy , abnormal
whole organism decreased size , abnormal
whole organism viability , abnormal
whole organism circling , abnormal
whole organism deformed , abnormal
whole organism anterior-posterior axis undulate , abnormal
whole organism decreased life span , abnormal
whole organism decreased mobility , abnormal
whole organism shortened , abnormal
whole organism degenerate , abnormal
whole organism axis shortened , abnormal
whole organism anterior-posterior axis bent , abnormal
whole organism chromosome damaged , abnormal
whole organism posterior region decreased amount , abnormal
whole organism neoplasm increased amount , abnormal
whole organism lethal (sensu genetics) , abnormal
whole organism cytosolic ribosome decreased amount , abnormal
whole organism sarcoma present , abnormal
whole organism axis truncated , abnormal
whole organism has fewer parts of type somite , abnormal
whole organism increased sensitivity to irradiation , abnormal
whole organism has fewer parts of type swim bladder , abnormal
whole organism anterior-posterior axis increased width , abnormal
whole organism anterior-posterior axis truncated , abnormal
whole organism apoptotic process occurrence , ameliorated
whole organism site of double-strand break increased amount , abnormal
whole organism increased amount , abnormal
whole organism monstrous , abnormal
whole organism amount , ameliorated
whole organism dorsal-ventral axis shortened , abnormal
whole organism decreased amount , abnormal
whole organism animal-vegetal axis elongated , abnormal
whole organism cell death increased occurrence , abnormal
whole organism bent , abnormal
whole organism neurofibrosarcoma increased amount , abnormal
whole organism neoplastic , exacerbated
whole organism neoplasm increased amount , exacerbated
whole organism neurofibrosarcoma increased amount , exacerbated
whole organism neurofibrosarcoma increased amount , ameliorated
whole organism neurofibrosarcoma apoptotic , abnormal
whole organism life span , ameliorated
whole organism lactate amount , ameliorated
whole organism elongated , abnormal
whole organism decreased life span , exacerbated
whole organism ventralized , abnormal
whole organism increased length , abnormal
whole organism melanoma increased amount , abnormal
Show

 ZFA:0001106 pharyngeal pouch pharyngeal pouch disorganized , abnormal
pharyngeal pouch closed , abnormal
pharyngeal pouch neural crest cell migration process quality , abnormal
pharyngeal pouch neural crest cell migration decreased occurrence , abnormal
Show

 ZFA:0001109 oocyte oocyte binucleate , abnormal
oocyte granular component disorganized , abnormal
oocyte chromosome morphology , abnormal
oocyte chromosome localized , abnormal
oocyte nucleolus asymmetrical , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head deformed , abnormal
head apoptotic , abnormal
head opaque , abnormal
head opacity , abnormal
head hypotrophic , abnormal
head malformed , abnormal
head flattened , abnormal
head necrotic , abnormal
head bulbous , abnormal
head anterior-posterior axis decreased length , abnormal
head melanoma present , abnormal
head hypoplastic , abnormal
head apoptotic process increased occurrence , abnormal
head morphology , ameliorated
head increased size , abnormal
head size , ameliorated
head morphology , abnormal
head cell death increased occurrence , abnormal
Show

 ZFA:0001115 trunk trunk posterior region decreased length , abnormal
trunk posterior region decreased size , abnormal
trunk curved dorsal , abnormal
trunk curved ventral , abnormal
trunk curved , abnormal
trunk sarcoma present , abnormal
trunk kinked , abnormal
trunk iridophore decreased amount , abnormal
trunk decreased size , abnormal
trunk curved lateral , abnormal
trunk increased curvature , abnormal
trunk decreased length , abnormal
trunk apoptotic , abnormal
trunk nerve sheath tumor neoplastic , abnormal
trunk morphology , abnormal
trunk truncated , abnormal
trunk increased distribution , abnormal
trunk posterior region increased distribution , abnormal
trunk posterior region mislocalised , abnormal
trunk central region has fewer parts of type dermomyotome , abnormal
trunk posterior region absent , abnormal
trunk ventral region absent , abnormal
Show

 ZFA:0001117 post-vent region post-vent region wholly dorsalized , abnormal
post-vent region decreased length , abnormal
post-vent region kinked , abnormal
post-vent region curved , abnormal
post-vent region curled , abnormal
post-vent region increased curvature , abnormal
post-vent region decreased flexibility , abnormal
post-vent region curved dorsal , abnormal
post-vent region bent , abnormal
post-vent region truncated , abnormal
post-vent region iridophore decreased amount , abnormal
post-vent region apoptotic , abnormal
post-vent region curved ventral , abnormal
post-vent region neoplastic , abnormal
post-vent region malformed , abnormal
post-vent region pigment cell decreased amount , abnormal
post-vent region deformed , abnormal
post-vent region aplastic , abnormal
post-vent region decreased size , abnormal
post-vent region hematopoietic stem cell decreased amount , abnormal
post-vent region erythroid progenitor cell amount , ameliorated
post-vent region hematopoietic multipotent progenitor cell amount , ameliorated
post-vent region erythroid progenitor cell decreased amount , abnormal
Show

 ZFA:0001120 neuroectoderm neuroectoderm pattern specification process occurrence , abnormal
neuroectoderm neural crest cell decreased amount , abnormal
neuroectoderm posterior region decreased distribution , abnormal
Show

 ZFA:0001135 neural tube neural tube closure incomplete , abnormal
neural tube neuron decreased amount , abnormal
neural tube apoptotic process increased occurrence , abnormal
neural tube morphology , abnormal
Show

 ZFA:0001157 posterior lateral line primordium posterior lateral line primordium cell proliferation decreased process quality , abnormal
posterior lateral line primordium cell division decreased process quality , abnormal
posterior lateral line primordium actin filament bundle organization process quality , abnormal
posterior lateral line primordium has fewer parts of type cell cell projection, abnormal
posterior lateral line primordium filopodium decreased length , abnormal
posterior lateral line primordium circular , abnormal
posterior lateral line primordium disorganized , abnormal
posterior lateral line primordium neuromast decreased amount , abnormal
posterior lateral line primordium morphology , abnormal
posterior lateral line primordium decreased size , abnormal
posterior lateral line primordium cell proliferation disrupted , abnormal
posterior lateral line primordium increased amount , abnormal
posterior lateral line primordium increased distribution , abnormal
posterior lateral line primordium decreased amount , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin decreased size , abnormal
pectoral fin morphology , abnormal
pectoral fin absent , abnormal
pectoral fin decreased length , abnormal
pectoral fin malformed , abnormal
Show

 ZFA:0001173 dorsal fin dorsal fin melanoma present , abnormal
Show

 ZFA:0001175 blastodisc blastodisc furrowed , abnormal
Show

 ZFA:0001194 cranial neural crest cranial neural crest decreased size , abnormal
Show

 ZFA:0001204 axial mesoderm axial mesoderm increased amount , abnormal
axial mesoderm increased distribution , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage malformed , abnormal
Meckels cartilage absent , abnormal
Meckels cartilage decreased size , abnormal
Meckels cartilage shortened , abnormal
Meckels cartilage shape , abnormal
Meckels cartilage circular , abnormal
Meckels cartilage bent , abnormal
Meckels cartilage curved ventral , abnormal
Meckels cartilage fused with Meckels cartilage , abnormal
Meckels cartilage fused with palatoquadrate cartilage , abnormal
Meckels cartilage hypoplastic , abnormal
Show

 ZFA:0001216 splanchnocranium splanchnocranium morphology , abnormal
splanchnocranium malformed , abnormal
splanchnocranium immature , abnormal
splanchnocranium hypoplastic , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton malformed , abnormal
mandibular arch skeleton decreased size , abnormal
mandibular arch skeleton shortened , abnormal
mandibular arch skeleton morphology , ameliorated
Show

 ZFA:0001239 ceratobranchial 5 bone ceratobranchial 5 bone perichondral ossification decreased process quality , abnormal
Show

 ZFA:0001249 exocrine pancreas exocrine pancreas decreased size , abnormal
exocrine pancreas hypoplastic , abnormal
Show

 ZFA:0001256 lateral floor plate lateral floor plate aplastic , abnormal
Show

 ZFA:0001257 medial floor plate medial floor plate morphology , abnormal
Show

 ZFA:0001260 endocrine pancreas endocrine pancreas decreased size , abnormal
Show

 ZFA:0001261 ventricular system ventricular system decreased size , abnormal
ventricular system increased volume , abnormal
ventricular system dilated , abnormal
ventricular system lumenized , abnormal
ventricular system malformed , abnormal
ventricular system morphology , abnormal
Show

 ZFA:0001267 cranial vasculature cranial vasculature morphology , abnormal
cranial vasculature broken , abnormal
Show

 ZFA:0001272 palatoquadrate arch palatoquadrate arch absent , abnormal
palatoquadrate arch decreased size , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch protruding , abnormal
ventral mandibular arch decreased size , abnormal
Show

 ZFA:0001282 adenohypophysis adenohypophysis has fewer parts of type adrenocorticotropic hormone secreting cell , abnormal
adenohypophysis corticotropin hormone secreting cell differentiation decreased occurrence , abnormal
Show

 ZFA:0001284 optic fissure optic fissure closure incomplete , abnormal
optic fissure morphology , abnormal
optic fissure present , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel decreased size , abnormal
intersegmental vessel branched , abnormal
intersegmental vessel extends beyond somite , abnormal
intersegmental vessel morphology , abnormal
intersegmental vessel malformed , abnormal
intersegmental vessel structure , abnormal
intersegmental vessel absent , abnormal
intersegmental vessel immature , abnormal
intersegmental vessel hypoplastic , abnormal
intersegmental vessel decreased length , abnormal
Show

 ZFA:0001286 caudal vein plexus caudal vein plexus decreased branchiness , abnormal
Show

 ZFA:0001289 ciliary marginal zone ciliary marginal zone increased size , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch absent , abnormal
pharyngeal arch cranial neural crest mislocalised , abnormal
pharyngeal arch apoptotic process increased process quality , abnormal
pharyngeal arch decreased size , abnormal
pharyngeal arch cranial neural crest cell absent , abnormal
pharyngeal arch migratory cranial neural crest cell decreased amount , abnormal
Show

 ZFA:0001307 pharyngeal musculature pharyngeal musculature decreased amount , abnormal
Show

 ZFA:0001315 atrioventricular canal atrioventricular canal distended , abnormal
Show

 ZFA:0001320 endocardium endocardium morphology , abnormal
endocardium decreased size , abnormal
Show

 ZFA:0001321 neurocranial trabecula neurocranial trabecula decreased size , abnormal
neurocranial trabecula absent , abnormal
Show

 ZFA:0001329 retinal inner plexiform layer retinal inner plexiform layer decreased thickness , abnormal
retinal inner plexiform layer position , abnormal
retinal inner plexiform layer spatial pattern , abnormal
Show

 ZFA:0001330 retinal outer plexiform layer retinal outer plexiform layer disorganized , abnormal
Show

 ZFA:0001338 intestine intestine well differentiated , abnormal
intestine hypoplastic , abnormal
intestine moderately well differentiated , abnormal
intestine poorly differentiated , abnormal
intestine morphology , abnormal
intestine apoptotic , abnormal
intestine chordoma present , abnormal
intestine amount , ameliorated
intestine distal region lacks all parts of type enteric neuron , abnormal
Show

 ZFA:0001345 interrenal gland interrenal gland neoplastic , abnormal
interrenal gland neuroblastoma present , exacerbated
Show

 ZFA:0001374 atrial myocardium atrial myocardium action potential increased duration , abnormal
Show

 ZFA:0001376 presumptive ectoderm presumptive ectoderm decreased distribution , abnormal
presumptive ectoderm decreased amount , abnormal
Show

 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage absent , abnormal
palatoquadrate cartilage decreased size , abnormal
palatoquadrate cartilage malformed , abnormal
palatoquadrate cartilage hypoplastic , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
ceratohyal cartilage absent , abnormal
ceratohyal cartilage decreased size , abnormal
ceratohyal cartilage morphology , abnormal
ceratohyal cartilage inverted , abnormal
ceratohyal cartilage curved , abnormal
ceratohyal cartilage bent , abnormal
ceratohyal cartilage polarity , ameliorated
ceratohyal cartilage fused with hyosymplectic cartilage , abnormal
ceratohyal cartilage curved ventral , abnormal
ceratohyal cartilage hypoplastic , abnormal
Show

 ZFA:0001405 ethmoid cartilage ethmoid cartilage absent , abnormal
ethmoid cartilage decreased size , abnormal
ethmoid cartilage malformed , abnormal
Show

 ZFA:0001414 occipital region occipital region absent , abnormal
Show

 ZFA:0001422 hyosymplectic cartilage hyosymplectic cartilage absent , abnormal
hyosymplectic cartilage decreased size , abnormal
hyosymplectic cartilage hypoplastic , abnormal
Show

 ZFA:0001423 parachordal cartilage parachordal cartilage decreased size , abnormal
Show

 ZFA:0001455 scapulocoracoid scapulocoracoid absent , abnormal
Show

 ZFA:0001456 pectoral fin endoskeletal disc pectoral fin endoskeletal disc decreased size , abnormal
Show

 ZFA:0001458 cranial cartilage cranial cartilage malformed , abnormal
cranial cartilage decreased size , abnormal
cranial cartilage morphology , ameliorated
cranial cartilage hypoplastic , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage malformed , abnormal
pharyngeal arch cartilage absent , abnormal
pharyngeal arch cartilage physical object quality , abnormal
pharyngeal arch cartilage decreased size , abnormal
pharyngeal arch cartilage poorly differentiated , abnormal
Show

 ZFA:0001461 chondrocranium cartilage chondrocranium cartilage malformed , abnormal
Show

 ZFA:0001462 somite border somite border muscle tendon junction morphology , abnormal
somite border deformed , abnormal
somite border disorganized , abnormal
somite border morphology , ameliorated
Show

 ZFA:0001466 photoreceptor outer segment layer photoreceptor outer segment layer absent , abnormal
Show

 ZFA:0001470 anterior lateral line anterior lateral line neuromast hair cell apoptotic , abnormal
Show

 ZFA:0001472 anterior lateral line neuromast anterior lateral line neuromast decreased amount , abnormal
Show

 ZFA:0001507 trabecula cranii trabecula cranii malformed , abnormal
Show

 ZFA:0001510 basihyal cartilage basihyal cartilage decreased size , abnormal
basihyal cartilage curved ventral , abnormal
Show

 ZFA:0001513 dermomyotome dermomyotome increased amount , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage absent , abnormal
ceratobranchial cartilage malformed , abnormal
ceratobranchial cartilage decreased amount , abnormal
ceratobranchial cartilage size , ameliorated
ceratobranchial cartilage hypoplastic , abnormal
Show

 ZFA:0001517 ceratobranchial 2 cartilage ceratobranchial 2 cartilage aplastic , abnormal
ceratobranchial 2 cartilage absent , abnormal
Show

 ZFA:0001518 ceratobranchial 3 cartilage ceratobranchial 3 cartilage aplastic , abnormal
ceratobranchial 3 cartilage absent , abnormal
Show

 ZFA:0001519 ceratobranchial 4 cartilage ceratobranchial 4 cartilage aplastic , abnormal
ceratobranchial 4 cartilage absent , abnormal
Show

 ZFA:0001520 ceratobranchial 1 cartilage ceratobranchial 1 cartilage aplastic , abnormal
ceratobranchial 1 cartilage absent , abnormal
Show

 ZFA:0001555 epibranchial ganglion epibranchial ganglion decreased amount , abnormal
epibranchial ganglion neuron decreased amount , abnormal
Show

 ZFA:0001557 pronephric glomerulus pronephric glomerulus cystic , abnormal
Show

 ZFA:0001558 pronephric tubule pronephric tubule dilated , abnormal
pronephric tubule cystic , abnormal
pronephric tubule morphology , ameliorated
pronephric tubule epithelial cell amount , ameliorated
pronephric tubule orientation whole organism anterior-posterior axis, abnormal
pronephric tubule decreased amount , abnormal
Show

 ZFA:0001565 oocyte stage II oocyte stage II degenerate , abnormal
Show

 ZFA:0001566 oocyte stage III oocyte stage III degenerate , abnormal
Show

 ZFA:0001606 pharyngeal arch 3 pharyngeal arch 3 has fewer parts of type chondroblast , abnormal
Show

 ZFA:0001608 pharyngeal arch 5 pharyngeal arch 5 immature , abnormal
pharyngeal arch 5 absent , abnormal
pharyngeal arch 5 has fewer parts of type cranial neural crest , abnormal
pharyngeal arch 5 has fewer parts of type chondroblast , abnormal
Show

 ZFA:0001609 pharyngeal arch 6 pharyngeal arch 6 absent , abnormal
pharyngeal arch 6 has fewer parts of type cranial neural crest , abnormal
pharyngeal arch 6 has fewer parts of type chondroblast , abnormal
Show

 ZFA:0001611 pharyngeal arch 2 pharyngeal arch 2 decreased distribution , abnormal
pharyngeal arch 2 absent , abnormal
Show

 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 malformed , abnormal
pharyngeal arch 1 decreased distribution , abnormal
pharyngeal arch 1 absent , abnormal
Show

 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 decreased size , abnormal
Show

 ZFA:0001617 otolith otolith fused with otolith , abnormal
otolith decreased amount , abnormal
otolith decreased size , abnormal
otolith morphology , abnormal
Show

 ZFA:0001620 pronephric proximal convoluted tubule pronephric proximal convoluted tubule distended , abnormal
pronephric proximal convoluted tubule straight , abnormal
pronephric proximal convoluted tubule mislocalised posteriorly , abnormal
pronephric proximal convoluted tubule increased length , abnormal
pronephric proximal convoluted tubule increased length , exacerbated
pronephric proximal convoluted tubule decreased length , abnormal
pronephric proximal convoluted tubule dilated , exacerbated
pronephric proximal convoluted tubule size , ameliorated
pronephric proximal convoluted tubule dilated , abnormal
Show

 ZFA:0001621 pronephric proximal straight tubule pronephric proximal straight tubule mislocalised posteriorly , abnormal
pronephric proximal straight tubule decreased length , abnormal
Show

 ZFA:0001622 pronephric distal early tubule pronephric distal early tubule mislocalised posteriorly , abnormal
pronephric distal early tubule decreased length , abnormal
Show

 ZFA:0001623 posterior pronephric duct posterior pronephric duct bent , abnormal
Show

 ZFA:0001624 pronephric distal late tubule pronephric distal late tubule increased length , abnormal
pronephric distal late tubule decreased length , abnormal
Show

 ZFA:0001673 pronephric podocyte pronephric podocyte absent , abnormal
Show

 ZFA:0001679 solid lens vesicle solid lens vesicle apoptotic process increased process quality , abnormal
Show

 ZFA:0001683 corneal epithelium corneal epithelium scalloped , abnormal
Show

 ZFA:0001687 corneal endothelium corneal endothelium absent , abnormal
Show

 ZFA:0001692 hindbrain commissure hindbrain commissure disorganized , abnormal
Show

 ZFA:0001707 brainstem brainstem neoplastic , abnormal
brainstem neoplasm increased amount , abnormal
Show

 ZFA:0001714 presumptive ventral mesoderm presumptive ventral mesoderm decreased amount , abnormal
Show

 ZFA:0005004 aortic arch aortic arch morphology , ameliorated
Show

 ZFA:0005023 hematopoietic system hematopoietic system posterior region amount , ameliorated
Show

 ZFA:0005024 trunk vasculature trunk vasculature morphology , abnormal
trunk vasculature broken , abnormal
Show

 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel malformed , abnormal
dorsal longitudinal anastomotic vessel incomplete structure , abnormal
dorsal longitudinal anastomotic vessel structure , abnormal
dorsal longitudinal anastomotic vessel immature , abnormal
Show

 ZFA:0005034 parachordal vessel parachordal vessel aplastic , abnormal
parachordal vessel immature , abnormal
Show

 ZFA:0005035 subintestinal vein subintestinal vein morphology , abnormal
subintestinal vein decreased length , abnormal
Show

 ZFA:0005037 post-vent vasculature post-vent vasculature edematous , abnormal
Show

 ZFA:0005046 hyaloid vessel hyaloid vessel irregular spatial pattern , abnormal
hyaloid vessel increased thickness , abnormal
hyaloid vessel hypoplastic , abnormal
hyaloid vessel blood vessel endothelial cell aggregated , abnormal
Show

 ZFA:0005061 ventricular myocardium ventricular myocardium action potential increased duration , abnormal
Show

 ZFA:0005064 atrioventricular valve atrioventricular valve decreased functionality , abnormal
Show

 ZFA:0005110 thoracic duct thoracic duct absent , abnormal
Show

 ZFA:0005124 intestinal epithelium intestinal epithelium has fewer parts of type epithelial cell , abnormal
intestinal epithelium increased amount , abnormal
Show

 ZFA:0005125 intestinal villus intestinal villus decreased length , abnormal
Show

 ZFA:0005145 muscle muscle detached from tendon , abnormal
muscle damaged , abnormal
muscle decreased mass , abnormal
Show

 ZFA:0005229 optic choroid optic choroid melanoma increased occurrence , abnormal
optic choroid melanocyte hyperplastic , abnormal
Show

 ZFA:0005237 erythroblast erythroblast decreased amount , abnormal
erythroblast increased size , abnormal
erythroblast nucleus structure , abnormal
Show

 ZFA:0005245 xanthoblast xanthoblast neural crest cell aggregated , abnormal
Show

 ZFA:0005249 vasculature vasculature hemorrhagic , abnormal
Show

 ZFA:0005277 skeletal muscle skeletal muscle morphology , abnormal
skeletal muscle disorganized , abnormal
skeletal muscle sarcomere disorganized , abnormal
Show

 ZFA:0005280 cardiac muscle cardiac muscle striated muscle thin filament decreased amount , abnormal
cardiac muscle adherens junction decreased amount , abnormal
cardiac muscle gap junction decreased amount , abnormal
cardiac muscle sarcomere morphology , abnormal
cardiac muscle cardiac myofibril morphology , abnormal
Show

 ZFA:0005283 renal capsular space renal capsular space morphology , ameliorated
Show

 ZFA:0005285 glomerular basement membrane glomerular basement membrane disorganized , abnormal
Show

 ZFA:0005313 pronephric glomerular basement membrane pronephric glomerular basement membrane increased permeability , abnormal
Show

 ZFA:0005314 blood vessel blood vessel morphology , abnormal
blood vessel increased branchiness , abnormal
Show

 ZFA:0005317 pectoral fin fold pectoral fin fold decreased size , abnormal
pectoral fin fold variability of size , abnormal
Show

 ZFA:0005335 swim bladder bud swim bladder bud hypoplastic , abnormal
Show

 ZFA:0005409 pars superior ear pars superior ear morphology , abnormal
Show

 ZFA:0005490 myocardial precursor myocardial precursor decreased amount , abnormal
Show

 ZFA:0005491 optic furrow optic furrow open , abnormal
Show

 ZFA:0005558 orbit orbit edematous , abnormal
Show

 ZFA:0005659 intestinal lamina propria mucosa intestinal lamina propria mucosa adenocarcinoma poorly differentiated , abnormal
intestinal lamina propria mucosa adenocarcinoma well differentiated , abnormal
intestinal lamina propria mucosa small cell carcinoma neoplastic , abnormal
Show

 ZFA:0005771 ectomesenchyme ectomesenchyme morphology , abnormal
Show

 ZFA:0005775 enteric neuron enteric neuron decreased length , abnormal
enteric neuron mislocalised , abnormal
enteric neuron decreased amount , abnormal
Show

 ZFA:0005781 cloaca cloaca malformed , abnormal
Show

 ZFA:0005784 striated muscle cell striated muscle cell length , ameliorated
striated muscle cell increased length , abnormal
striated muscle cell decreased width , abnormal
striated muscle cell width , ameliorated
Show

 ZFA:0005792 jaw flap jaw flap breeding tubercle decreased size , abnormal
Show

 ZFA:0009000 cell cell increased size , abnormal
cell autophagosome accumulation cell perinuclear region of cytoplasm, abnormal
cell autolysosome accumulation cell perinuclear region of cytoplasm, abnormal
Show

 ZFA:0009003 cranial neural crest cell cranial neural crest cell decreased amount , abnormal
cranial neural crest cell mislocalised , abnormal
cranial neural crest cell cell proliferation decreased process quality , abnormal
cranial neural crest cell cell death increased occurrence , abnormal
cranial neural crest cell filopodium decreased length , abnormal
cranial neural crest cell filopodium decreased amount , abnormal
Show

 ZFA:0009004 trunk neural crest cell trunk neural crest cell mislocalised , abnormal
Show

 ZFA:0009014 hematopoietic stem cell hematopoietic stem cell decreased amount , abnormal
hematopoietic stem cell amount , ameliorated
Show

 ZFA:0009015 erythroid progenitor cell erythroid progenitor cell amount , ameliorated
Show

 ZFA:0009019 neuronal stem cell neuronal stem cell apoptotic , abnormal
Show

 ZFA:0009021 common myeloid progenitor common myeloid progenitor amount , ameliorated
Show

 ZFA:0009023 common lymphoid progenitor common lymphoid progenitor decreased amount , abnormal
Show

 ZFA:0009031 osteoblast osteoblast decreased distribution , abnormal
osteoblast decreased amount , abnormal
osteoblast absent , abnormal
Show

 ZFA:0009036 blood vessel endothelial cell blood vessel endothelial cell has fewer parts of type blood vessel endothelial cell cell-cell junction, abnormal
blood vessel endothelial cell adherens junction immature , abnormal
Show

 ZFA:0009044 blood cell blood cell decreased amount , abnormal
Show

 ZFA:0009048 granulocyte granulocyte decreased amount , abnormal
granulocyte morphology , abnormal
Show

 ZFA:0009052 motor neuron motor neuron axon decreased length , abnormal
motor neuron axon unbranched , abnormal
motor neuron axon terminus decreased amount , abnormal
motor neuron axon decreased amount , abnormal
motor neuron axon increased branchiness , abnormal
motor neuron axon shortened , abnormal
Show

 ZFA:0009055 bipolar neuron bipolar neuron postsynaptic density absent , abnormal
Show

 ZFA:0009063 peripheral neuron peripheral neuron myelin sheath neoplastic , abnormal
Show

 ZFA:0009065 endothelial cell endothelial cell apoptotic process increased occurrence , ameliorated
Show

 ZFA:0009076 oligodendrocyte oligodendrocyte cell migration decreased process quality , abnormal
oligodendrocyte cell division decreased process quality , abnormal
oligodendrocyte cell migration increased occurrence , abnormal
oligodendrocyte cell migration increased process quality , abnormal
oligodendrocyte increased amount , abnormal
oligodendrocyte TOR signaling increased occurrence , abnormal
oligodendrocyte MAPK cascade decreased occurrence , abnormal
oligodendrocyte TOR signaling decreased occurrence , abnormal
oligodendrocyte TOR signaling occurrence , ameliorated
oligodendrocyte myelin sheath decreased length , abnormal
oligodendrocyte myelin sheath length , ameliorated
oligodendrocyte myelin sheath increased length , abnormal
oligodendrocyte myelin sheath decreased length , ameliorated
Show

 ZFA:0009090 pigment cell pigment cell decreased amount , abnormal
Show

 ZFA:0009091 melanocyte melanocyte decreased amount , abnormal
melanocyte neoplastic , abnormal
melanocyte nucleus pleomorphic , abnormal
melanocyte melanoma increased occurrence , abnormal
melanocyte melanoma increased amount , abnormal
melanocyte low saturation , abnormal
melanocyte decreased size , abnormal
melanocyte pigment granule decreased amount , abnormal
Show

 ZFA:0009111 hepatocyte hepatocyte hyperplastic , abnormal
hepatocyte fatty , abnormal
hepatocyte mitotic cell cycle increased frequency , abnormal
hepatocyte nucleus increased size , abnormal
hepatocyte nucleolus prominent , abnormal
hepatocyte morphology , abnormal
hepatocyte nucleus morphology , abnormal
hepatocyte morphology , ameliorated
hepatocyte apoptotic process process quality , ameliorated
Show

 ZFA:0009114 muscle cell muscle cell apoptotic , abnormal
Show

 ZFA:0009115 skeletal muscle cell skeletal muscle cell morphology , abnormal
skeletal muscle cell irregular spatial pattern , abnormal
skeletal muscle cell disorganized , abnormal
Show

 ZFA:0009116 slow muscle cell slow muscle cell mislocalised , abnormal
slow muscle cell decreased amount , abnormal
slow muscle cell calcium-mediated signaling process quality , abnormal
slow muscle cell calcium-mediated signaling process quality , ameliorated
slow muscle cell amount , ameliorated
slow muscle cell sarcomere morphology , abnormal
slow muscle cell sarcomere morphology , ameliorated
slow muscle cell skeletal muscle myofibril disorganized , abnormal
slow muscle cell skeletal muscle myofibril organization quality , ameliorated
Show

 ZFA:0009117 fast muscle cell fast muscle cell muscle fiber development decreased process quality , abnormal
fast muscle cell decreased amount , abnormal
fast muscle cell has fewer parts of type fast muscle cell nucleus, abnormal
fast muscle cell disorganized , abnormal
fast muscle cell disheveled , abnormal
fast muscle cell decreased diameter , abnormal
Show

 ZFA:0009138 mesodermal cell mesodermal cell filamentous actin oriented , abnormal
Show

 ZFA:0009141 macrophage macrophage decreased amount , abnormal
macrophage response to wounding process quality , abnormal
Show

 ZFA:0009149 Mauthner neuron Mauthner neuron decreased amount , abnormal
Show

 ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron decreased amount , abnormal
Show

 ZFA:0009165 neural crest cell neural crest cell mislocalised , abnormal
neural crest cell aggregated , abnormal
neural crest cell endosome immature , abnormal
neural crest cell early endosome increased amount , abnormal
neural crest cell early endosome increased size , abnormal
neural crest cell early endosome aggregated , abnormal
neural crest cell late endosome decreased size , abnormal
neural crest cell late endosome decreased amount , abnormal
neural crest cell endocytosis process quality , abnormal
Show

 ZFA:0009182 gastrula cell gastrula cell chromosome morphology , abnormal
Show

 ZFA:0009199 iridophore iridophore decreased amount , abnormal
Show

 ZFA:0009248 neuron neuron positive regulation of ERK1 and ERK2 cascade increased occurrence , abnormal
neuron apoptotic , abnormal
neuron decreased amount , abnormal
Show

 ZFA:0009249 melanoblast melanoblast neural crest cell aggregated , abnormal
Show

 ZFA:0009255 amacrine cell amacrine cell absent , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
nucleate erythrocyte immature , abnormal
nucleate erythrocyte mislocalised , abnormal
nucleate erythrocyte fluorescence , abnormal
nucleate erythrocyte hemoglobin complex decreased amount , abnormal
Show

 ZFA:0009258 angioblastic mesenchymal cell angioblastic mesenchymal cell amount , ameliorated
Show

 ZFA:0009262 retinal cone cell retinal cone cell decreased amount , abnormal
Show

 ZFA:0009280 Muller cell Muller cell decreased amount , abnormal
Muller cell absent , abnormal
Show

 ZFA:0009285 podocyte podocyte non-functional , abnormal
podocyte cell projection disorganized , abnormal
podocyte disorganized , abnormal
podocyte cell projection absent , abnormal
Show

 ZFA:0009288 primordial germ cell primordial germ cell cell motility decreased speed , abnormal
primordial germ cell cell motility decreased occurrence , abnormal
Show

 ZFA:0009310 retinal ganglion cell retinal ganglion cell decreased amount , abnormal
retinal ganglion cell absent , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell decreased amount , abnormal
cardiac muscle cell decreased size , abnormal
cardiac muscle cell cell proliferation decreased process quality , abnormal
cardiac muscle cell increased amount , abnormal
cardiac muscle cell vacuolated , abnormal
cardiac muscle cell autophagosome present , abnormal
Show

 ZFA:0009324 myeloid cell myeloid cell decreased amount , abnormal
Show

 ZFA:0009325 erythroid lineage cell erythroid lineage cell decreased amount , abnormal
erythroid lineage cell amount , ameliorated
Show

 ZFA:0009327 neutrophil neutrophil decreased amount , abnormal
neutrophil phagocytosis decreased process quality , abnormal
neutrophil morphology , abnormal
neutrophil spatial pattern , abnormal
Show

 ZFA:0009354 hematopoietic multipotent progenitor cell hematopoietic multipotent progenitor cell decreased amount , abnormal
hematopoietic multipotent progenitor cell amount , ameliorated
Show

 ZFA:0009356 myeloid lineage restricted progenitor cell myeloid lineage restricted progenitor cell increased size , abnormal
Show

 ZFA:0009367 neuromast hair cell neuromast hair cell decreased functionality , abnormal
neuromast hair cell decreased amount , abnormal
Show

 ZFA:0009368 slow muscle myoblast slow muscle myoblast increased amount , abnormal
Show

 ZFA:0009395 vascular lymphangioblast vascular lymphangioblast malformed , abnormal
vascular lymphangioblast decreased amount , abnormal
vascular lymphangioblast absent , abnormal
vascular lymphangioblast absent , ameliorated
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000002385 atm / ATM serine/threonine kinase / Q13315* / Q62388* / Serine-protein kinase ATM *  / reaction
 ENSDARG00000009899 znf385a / zinc finger protein 385A / Q8VD12* / Q96PM9* / Zfp385a*  / complex / reaction
 ENSDARG00000018907 kat6a / K(lysine) acetyltransferase 6A / Q92794* / lysine acetyltransferase 6A*  / complex
 ENSDARG00000009136 tp53bp2a / tumor protein p53 binding protein, 2a / Q13625* / TP53BP2* / Trp53bp2* / tumor protein p53 binding protein 2* / transformation related protein 53 binding protein 2*  / reaction / complex
 ENSDARG00000020086 nuak1a / NUAK family, SNF1-like kinase, 1a / NUAK1* / Q641K5* / O60285* / NUAK family kinase 1* / NUAK family SNF1-like kinase 1 *  / reaction / complex
 ENSDARG00000017537 prkag3a / protein kinase, AMP-activated, gamma 3a non-catalytic subunit / Q9UGI9* / PRKAG3* / Q8BGM7* / protein kinase AMP-activated non-catalytic subunit gamma 3* / protein kinase, AMP-act...  / reaction
 ENSDARG00000003818 prkag1 / protein kinase, AMP-activated, gamma 1 non-catalytic subunit / O54950* / P54619* / protein kinase AMP-activated non-catalytic subunit gamma 1*  / reaction
 ENSDARG00000013719 gtse1 / G-2 and S-phase expressed 1 / Q8R080* / Q9NYZ3* / G2 and S phase-expressed protein 1 *  / reaction / complex
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000073710 usp7 / ubiquitin specific peptidase 7 (herpes virus-associated) / Q93009* / ubiquitin specific peptidase 7*  / reaction
 ENSDARG00000026577 cdk2 / cyclin-dependent kinase 2 / P24941* / P97377*  / reaction
 ENSDARG00000046143 prkab1b / protein kinase, AMP-activated, beta 1 non-catalytic subunit, b / PRKAB1* / Q9R078* / Q9Y478* / protein kinase AMP-activated non-catalytic subunit beta 1* / protein kinase, AMP-act...  / reaction
 ENSDARG00000035330 taf1 / TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor / TAF1L* / P21675* / Q80UV9* / Q8IZX4* / TATA-box binding protein associated factor 1* / TATA-box binding pro...  / reaction
 ENSDARG00000057513 mdm4 / MDM4, p53 regulator / O15151*  / reaction / complex
 ENSDARG00000037262 cdkn2a/b / cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4) / CDKN2A* / CDKN2B* / P42772* / P55271* / Q8N726* / P42771* / cyclin dependent kinase inhibitor 2A* / cyclin dependent...  / complex / reaction
 ENSDARG00000104907 ing2 / inhibitor of growth family, member 2 / Q9ESK4* / Q9H160* / Inhibitor of growth protein 2 *  / complex / reaction
 ENSDARG00000101216 meaf6 / Q6AZD3 / MYST/Esa1-associated factor 6 / Q2VPQ9* / Q9HAF1*  / complex
 ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53*  / reaction / complex
 ENSDARG00000103422 usp10 / ubiquitin specific peptidase 10 / P52479* / Q14694*  / complex
 ENSDARG00000008380 brd7 / bromodomain containing 7 / O88665* / Q9NPI1* / Bromodomain-containing protein 7 *  / complex / reaction
 ENSDARG00000077300 usp42 / ubiquitin specific peptidase 42 / B2RQC2* / Q9H9J4*  / complex
 ENSDARG00000022413 ing5a / inhibitor of growth family, member 5a / ING5* / Q8WYH8* / Q9D8Y8* / Inhibitor of growth protein 5 * / inhibitor of growth family member 5*  / complex
 ENSDARG00000033443 mdm2 / MDM2 oncogene, E3 ubiquitin protein ligase / P23804* / Q00987* / MDM2 proto-oncogene* / E3 ubiquitin-protein ligase Mdm2 *  / reaction / complex
 ENSDARG00000028676 nuak1b / NUAK family, SNF1-like kinase, 1b / NUAK1* / Q641K5* / O60285* / NUAK family kinase 1* / NUAK family SNF1-like kinase 1 *  / complex / reaction
 ENSDARG00000013582 csnk2a2b / casein kinase 2, alpha prime polypeptide b / P19784* / O54833* / CSNK2A2* / casein kinase 2 alpha 2* / Casein kinase II subunit alpha *  / reaction
 ENSDARG00000009142 ppp1r13bb / protein phosphatase 1, regulatory subunit 13Bb / Q96KQ4* / Q62415* / PPP1R13B* / protein phosphatase 1 regulatory subunit 13B* / protein phosphatase 1, regulatory (inhibitor) subunit 13B*  / complex / reaction
 ENSDARG00000028119 Q6NV25 / sumo3a / small ubiquitin-like modifier 3a / SUMO3* / Q9Z172* / P55854* / small ubiquitin-like modifier 3*  / reaction
 ENSDARG00000035993 sumo3b / small ubiquitin-like modifier 3b / SUMO3* / P55854* / small ubiquitin-like modifier 3*  / reaction
 ENSDARG00000005629 Q5RGL7 / smyd2b / SET and MYND domain containing 2b / SMYD2* / Q8R5A0* / Q9NRG4* / SET and MYND domain containing 2* / N-lysine methyltransferase SMYD2 *  / reaction
 ENSDARG00000004377 ppp1r13ba / protein phosphatase 1, regulatory subunit 13Ba / Q96KQ4* / Q62415* / PPP1R13B* / protein phosphatase 1 regulatory subunit 13B* / protein phosphatase 1, regulatory (inhibitor) subunit 13B*  / complex / reaction
 ENSDARG00000028017 tp53inp1 / tumor protein p53 inducible nuclear protein 1 / Q9QXE4* / Q96A56* / Trp53inp1* / transformation related protein 53 inducible nuclear protein 1*  / complex
 ENSDARG00000094646 dyrk2 / dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 / Q5U4C9* / Q92630* / dual specificity tyrosine phosphorylation regulated kinase 2*  / reaction
 ENSDARG00000060596 prkaa1 / protein kinase, AMP-activated, alpha 1 catalytic subunit / Q13131* / Q5EG47* / protein kinase AMP-activated catalytic subunit alpha 1*  / reaction
 ENSDARG00000045087 cdk5r1b / cyclin-dependent kinase 5, regulatory subunit 1b (p35) / Q15078* / P61809* / CDK5R1* / cyclin dependent kinase 5 regulatory subunit 1* / Cyclin-dependent kinase 5 activator 1 Cycl...  / reaction
 ENSDARG00000037640 aurkb / aurora kinase B / AURKC* / Q9UQB9* / Q96GD4* / aurora kinase C*  / reaction / complex
 ENSDARG00000056683 cdk5 / cyclin-dependent kinase 5 / P49615* / Q00535* / Cyclin-dependent-like kinase 5 *  / reaction
 ENSDARG00000001754 noc2l / NOC2-like nucleolar associated transcriptional repressor / Q9Y3T9*  / reaction / complex
 ENSDARG00000060641 prkaa2 / protein kinase, AMP-activated, alpha 2 catalytic subunit / P54646* / protein kinase AMP-activated catalytic subunit alpha 2*  / reaction
 ENSDARG00000038737 phf20b / PHD finger protein 20, b / PHF20* / Q8BLG0* / Q9BVI0* / PHD finger protein 20*  / complex / reaction
 ENSDARG00000044183 prkab1a / protein kinase, AMP-activated, beta 1 non-catalytic subunit, a / PRKAB1* / Q9R078* / Q9Y478* / protein kinase AMP-activated non-catalytic subunit beta 1* / protein kinase, AMP-act...  / reaction
 ENSDARG00000037916 cdk5r1a / cyclin-dependent kinase 5, regulatory subunit 1a (p35) / Q15078* / P61809* / CDK5R1* / cyclin dependent kinase 5 regulatory subunit 1* / Cyclin-dependent kinase 5 activator 1 Cycl...  / reaction
 ENSDARG00000052826 runx3 / runt-related transcription factor 3 / Q13761* / Q64131*  / complex / reaction
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000069737 pou4f2 / POU class 4 homeobox 2 / Q12837* / Q63934* / POU domain, class 4, transcription factor 2 *  / reaction / complex
 ENSDARG00000077776 Q91398 / csnk2b / casein kinase 2, beta polypeptide / P67870* / P67871* / casein kinase 2 beta* / Casein kinase II subunit beta *  / reaction
 ENSDARG00000002750 phf20a / PHD finger protein 20, a / PHF20* / Q8BLG0* / Q9BVI0* / PHD finger protein 20*  / reaction / complex
 ENSDARG00000067817 CABZ01083448.1 / O43741* / PRKAB2* / protein kinase AMP-activated non-catalytic subunit beta 2*  / reaction
 ENSDARG00000063076 atrip / ATR interacting protein / Q8BMG1* / Q8WXE1*  / reaction
 ENSDARG00000000369 prkag3b / protein kinase, AMP-activated, gamma 3b non-catalytic subunit / Q9UGI9* / PRKAG3* / Q8BGM7* / protein kinase AMP-activated non-catalytic subunit gamma 3* / protein kinase, AMP-act...  / reaction
 ENSDARG00000054858 tp53bp2b / tumor protein p53 binding protein, 2b / Q13625* / TP53BP2* / Trp53bp2* / tumor protein p53 binding protein 2* / transformation related protein 53 binding protein 2*  / reaction / complex
 ENSDARG00000013777 ppp1r13l / protein phosphatase 1, regulatory subunit 13 like / Q5I1X5* / Q8WUF5* / protein phosphatase 1, regulatory (inhibitor) subunit 13 like*  / reaction / complex
 ENSDARG00000079949 supt16h / SPT16 homolog, facilitates chromatin remodeling subunit / Q9Y5B9* / Supt16* / suppressor of Ty 16*  / reaction
 ENSDARG00000038754 plk3 / polo-like kinase 3 (Drosophila) / Q9H4B4* / polo like kinase 3* / serine/threonine-protein kinase PLK3 isoform 2 *  / reaction
 ENSDARG00000028082 mapkapk5 / mitogen-activated protein kinase-activated protein kinase 5 / Q8IW41*  / reaction
 ENSDARG00000104114 kmt5ab / lysine methyltransferase 5Ab / KMT5A* / Q9NQR1* / lysine methyltransferase 5A*  / reaction
 ENSDARG00000102741 sumo2b / Q6DHL4 / small ubiquitin-like modifier 2b / SUMO4* / SUMO2* / Q6EEV6* / P61956* / P61957* / small ubiquitin-like modifier 4* / small ubiquitin-like modifier 2*  / reaction
 ENSDARG00000105231 kmt5aa / lysine methyltransferase 5Aa / KMT5A* / Q9NQR1* / lysine methyltransferase 5A*  / reaction
 ENSDARG00000101915 pin1 / peptidylprolyl cis/trans isomerase, NIMA-interacting 1 / Q13526*  / complex
 ENSDARG00000104765 chek1 / checkpoint kinase 1 / O14757* / O35280* / Serine/threonine-protein kinase Chk1 *  / reaction
 ENSDARG00000112667 tp53rk / TP53 regulating kinase / Q96S44*  / reaction






 

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