ENSDARG00000069737


Danio rerio

Features
Gene ID: ENSDARG00000069737
  
Biological name :pou4f2
  
Synonyms : pou4f2 / POU class 4 homeobox 2
  
Possible biological names infered from orthology : POU domain, class 4, transcription factor 2 / Q12837 / Q63934
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 36436936
Gene end: 36440301
  
Corresponding Affymetrix probe sets: Dr.13574.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000111629
Ensembl peptide - ENSDARP00000149865
NCBI entrez gene - 402816     See in Manteia.
swissprot - Q6XZH0
swissprot - Q6XZH1
ZFIN ID - ZDB-GENE-040401-1
Ensembl - ENSDARG00000069737
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 POU4F2ENSGALG00000037094Gallus gallus
 POU4F2ENSG00000151615Homo sapiens
 Pou4f2ENSMUSG00000031688Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pou4f1 / POU class 4 homeobox 1 / Q01851*ENSDARG0000000555967
zgc:158291ENSDARG0000004437565
pou4f3 / Q90435 / POU class 4 homeobox 3 / Q15319*ENSDARG0000000620664
P79745 / pou3f3b / POU class 3 homeobox 3bENSDARG0000009589628
P56224 / pou3f3a / POU class 3 homeobox 3aENSDARG0000004203228
pou1f1 / POU class 1 homeobox 1 / P28069* / Q00286* / POU domain, class 1, transcription factor 1*ENSDARG0000005892426
P79746 / pou3f2b / POU class 3 homeobox 2b / POU3F2* / P20265* / P31360* / POU class 3 homeobox 2* / POU domain, class 3, transcription factor 2*ENSDARG0000007626226
pou2f2a / POU class 2 homeobox 2a / Q00196* / P09086* / POU2F2* / POU class 2 homeobox 2* / POU domain, class 2, transcription factor 2 *ENSDARG0000001965825
pou2f2a / POU class 2 homeobox 2a / Q00196* / P09086* / POU2F2* / POU class 2 homeobox 2* / POU domain, class 2, transcription factor 2 *ENSDARG0000003681624
pou2f3 / POU class 2 homeobox 3 / Q9UKI9*ENSDARG0000005238724
pou3f2a / POU class 3 homeobox 2aENSDARG0000007022023
Q90482 / pou3f1 / POU class 3 homeobox 1 / Q03052* / P21952* / POU domain, class 3, transcription factor 1 *ENSDARG0000000982323
pou5f3 / POU domain, class 5, transcription factor 3 / POU5F2* / Q8N7G0* / P20263* / POU5F1* / Q01860* / Q06416* / POU5F1B* / POU class 5 homeobox 1* / POU class 5 homeobox 1B* / POU domain...ENSDARG0000004477422
pou2f1b / POU class 2 homeobox 1b / P25425* / POU2F1* / P14859* / POU class 2 homeobox 1* / POU domain, class 2, transcription factor 1 *ENSDARG0000000799622


Protein motifs (from Interpro)
Interpro ID Name
 IPR000327  POU-specific domain
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily
 IPR013847  POU domain
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007420 brain development IEP
 biological_processGO:0007507 heart development IGI
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Association with Co-factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart linear , abnormal
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 ZFA:0000154 sinus venosus sinus venosus decreased thickness , abnormal
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 ZFA:0001094 whole organism whole organism decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53*  / complex / reaction






 

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