ENSDARG00000035330


Danio rerio

Features
Gene ID: ENSDARG00000035330
  
Biological name :taf1
  
Synonyms : taf1 / TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor
  
Possible biological names infered from orthology : P21675 / Q80UV9 / Q8IZX4 / TAF1L / TATA-box binding protein associated factor 1 / TATA-box binding protein associated factor 1 like
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 36551470
Gene end: 36592394
  
Corresponding Affymetrix probe sets: Dr.11396.1.A1_at (Zebrafish Array)   NM_001044785_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000051195
Ensembl peptide - ENSDARP00000104582
NCBI entrez gene - 555452     See in Manteia.
RefSeq - NM_001044785
RefSeq - XM_005165316
RefSeq Peptide - NP_001038250
swissprot - Q1LYC2
swissprot - F1R1I4
ZFIN ID - ZDB-GENE-030131-5576
Ensembl - ENSDARG00000035330
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000005464Gallus gallus
 TAF1ENSG00000147133Homo sapiens
 TAF1LENSG00000122728Homo sapiens
 Taf1ENSMUSG00000031314Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zmynd8 / zinc finger, MYND-type containing 8 / Q9ULU4*ENSDARG0000000760110
prkcbp1l / protein kinase C binding protein 1, like / Q9ULU4* / ZMYND8* / zinc finger MYND-type containing 8*ENSDARG000000119329
zmynd11 / zinc finger, MYND-type containing 11 / Q15326* / Q8R5C8* / zinc finger, MYND domain containing 11*ENSDARG000000572494


Protein motifs (from Interpro)
Interpro ID Name
 IPR001487  Bromodomain
 IPR009067  TAFII-230 TBP-binding
 IPR011177  Transcription initiation factor TFIID subunit 1, animal
 IPR018359  Bromodomain, conserved site
 IPR022591  Transcription initiation factor TFIID subunit 1, domain of unknown function


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006352 DNA-templated transcription, initiation IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0030901 midbrain development IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0051123 RNA polymerase II transcriptional preinitiation complex assembly IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005669 transcription factor TFIID complex IBA
 molecular_functionGO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly IBA
 molecular_functionGO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IBA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0017025 TBP-class protein binding IBA
 molecular_functionGO:0043565 sequence-specific DNA binding IBA


Pathways (from Reactome)
Pathway description
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000445 optic tectum optic tectum decreased area , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53*  / reaction






 

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