ENSG00000122728


Homo sapiens

Features
Gene ID: ENSG00000122728
  
Biological name :TAF1L
  
Synonyms : Q8IZX4 / TAF1L / TATA-box binding protein associated factor 1 like
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: p21.1
Gene start: 32629454
Gene end: 32635669
  
Corresponding Affymetrix probe sets: 1553011_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418379
NCBI entrez gene - 138474     See in Manteia.
OMIM - 607798
RefSeq - NM_153809
RefSeq Peptide - NP_722516
swissprot - Q8IZX4
Ensembl - ENSG00000122728
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 taf1ENSDARG00000035330Danio rerio
 ENSGALG00000005464Gallus gallus
 Taf1ENSMUSG00000031314Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TAF1 / P21675 / TATA-box binding protein associated factor 1ENSG0000014713393
Q9ULU4 / ZMYND8 / zinc finger MYND-type containing 8ENSG0000010104011
Q15326 / ZMYND11 / zinc finger MYND-type containing 11ENSG000000151715


Protein motifs (from Interpro)
Interpro ID Name
 IPR001487  Bromodomain
 IPR009067  TAFII-230 TBP-binding
 IPR011177  Transcription initiation factor TFIID subunit 1, animal
 IPR018359  Bromodomain, conserved site
 IPR022591  Transcription initiation factor TFIID subunit 1, domain of unknown function
 IPR036427  Bromodomain-like superfamily
 IPR036741  TAFII-230 TBP-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006352 DNA-templated transcription, initiation IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter TAS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007140 male meiotic nuclear division IEP
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0051123 RNA polymerase II transcriptional preinitiation complex assembly IEA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005669 transcription factor TFIID complex IBA
 molecular_functionGO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly IBA
 molecular_functionGO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IBA
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017025 TBP-class protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IBA
 molecular_functionGO:0070577 lysine-acetylated histone binding IDA


Pathways (from Reactome)
Pathway description
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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