ENSDARG00000105231


Danio rerio

Features
Gene ID: ENSDARG00000105231
  
Biological name :kmt5aa
  
Synonyms : kmt5aa / lysine methyltransferase 5Aa
  
Possible biological names infered from orthology : KMT5A / lysine methyltransferase 5A / Q9NQR1
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 44363195
Gene end: 44373370
  
Corresponding Affymetrix probe sets: Dr.7640.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000140543
swissprot - A0A0R4IXW2
ZFIN ID - ZDB-GENE-060825-37
Ensembl - ENSDARG00000105231
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KMT5AENSGALG00000003325Gallus gallus
 KMT5AENSG00000183955Homo sapiens
 Kmt5aENSMUSG00000049327Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kmt5ab / lysine methyltransferase 5Ab / KMT5A* / Q9NQR1* / lysine methyltransferase 5A*ENSDARG0000010411440


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR016858  Class V SAM-dependent methyltransferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034968 histone lysine methylation IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Condensation of Prophase Chromosomes
PKMTs methylate histone lysines
Regulation of TP53 Activity through Methylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000071 shield shield increased width , abnormal
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 ZFA:0000079 telencephalon telencephalon increased size , abnormal
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 ZFA:0001115 trunk trunk decreased length , abnormal
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 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53*  / reaction
 ENSDARG00000018111 kdm7aa / Q5RHD1 / lysine (K)-specific demethylase 7Aa / PHF8* / Q80TJ7* / Q9UPP1* / 4921501E09Rik* / PHD finger protein 8* / RIKEN cDNA 4921501E09 gene* / Histone lysine demethylase PHF8 *  / reaction
 ENSDARG00000006584 phf8 / P0CH95 / PHD finger protein 8 / Q80TJ7* / Q9UPP1* / 4921501E09Rik* / RIKEN cDNA 4921501E09 gene* / Histone lysine demethylase PHF8 *  / reaction






 

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