ENSDARG00000104907


Danio rerio

Features
Gene ID: ENSDARG00000104907
  
Biological name :ing2
  
Synonyms : ing2 / inhibitor of growth family, member 2
  
Possible biological names infered from orthology : Inhibitor of growth protein 2 / Q9ESK4 / Q9H160
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 39981451
Gene end: 39983730
  
Corresponding Affymetrix probe sets: Dr.5816.1.A1_at (Zebrafish Array)   NM_001002448_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000134787
NCBI entrez gene - 436721     See in Manteia.
RefSeq - NM_001002448
RefSeq Peptide - NP_001002448
swissprot - Q6DHF1
ZFIN ID - ZDB-GENE-040718-147
Ensembl - ENSDARG00000104907
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ING2ENSGALG00000010659Gallus gallus
 ING2ENSG00000168556Homo sapiens
 Ing2ENSMUSG00000063049Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ing5a / inhibitor of growth family, member 5a / ING5* / Q8WYH8* / Q9D8Y8* / Inhibitor of growth protein 5 * / inhibitor of growth family member 5*ENSDARG0000002241331
ing3 / inhibitor of growth family, member 3 / Q8VEK6* / Q9NXR8* / Inhibitor of growth protein 3 *ENSDARG0000003432631
ing4 / inhibitor of growth family, member 4 / Q8C0D7* / Q9UNL4* / Inhibitor of growth protein 4 *ENSDARG0000003071630
ing5b / inhibitor of growth family, member 5b / ING5* / Q8WYH8* / Q9D8Y8* / Inhibitor of growth protein 5 * / inhibitor of growth family member 5*ENSDARG0000006817529
ing1 / inhibitor of growth family, member 1 / Q9QXV3* / Q9UK53* / Inhibitor of growth protein 1 *ENSDARG0000001911626


Protein motifs (from Interpro)
Interpro ID Name
 IPR001965  Zinc finger, PHD-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR024610  Inhibitor of growth protein, N-terminal histone-binding
 IPR028639  Inhibitor of growth protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:2000772 regulation of cellular senescence IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription cofactors
PI5P Regulates TP53 Acetylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53*  / complex / reaction
 ENSDARG00000044267 sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *  / reaction / complex
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction






 

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