ENSDARG00000001754


Danio rerio

Features
Gene ID: ENSDARG00000001754
  
Biological name :noc2l
  
Synonyms : noc2l / NOC2-like nucleolar associated transcriptional repressor
  
Possible biological names infered from orthology : Q9Y3T9
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 23126130
Gene end: 23179417
  
Corresponding Affymetrix probe sets: Dr.2399.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000113596
Ensembl peptide - ENSDARP00000086095
Ensembl peptide - ENSDARP00000105346
NCBI entrez gene - 58013     See in Manteia.
RefSeq - NM_001003830
RefSeq - XM_017353600
RefSeq Peptide - NP_001003830
swissprot - F1QP79
swissprot - F1QFC4
swissprot - F1RAA5
ZFIN ID - ZDB-GENE-000607-75
Ensembl - ENSDARG00000001754
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NOC2LENSGALG00000002222Gallus gallus
 NOC2LENSG00000188976Homo sapiens
 Noc2lENSMUSG00000095567Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005343  Nucleolar complex protein 2
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0035067 negative regulation of histone acetylation IBA
 biological_processGO:0042273 ribosomal large subunit biogenesis IBA
 cellular_componentGO:0005654 nucleoplasm IBA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0030690 Noc1p-Noc2p complex IBA
 cellular_componentGO:0030691 Noc2p-Noc3p complex IBA
 molecular_functionGO:0003714 transcription corepressor activity IBA
 molecular_functionGO:0042393 histone binding IBA
 molecular_functionGO:0070491 repressing transcription factor binding IBA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000084 yolk yolk quality , abnormal
yolk circular , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
Show

 ZFA:0000123 liver liver quality , abnormal
liver hypoplastic , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000037640 aurkb / aurora kinase B / AURKC* / Q9UQB9* / Q96GD4* / aurora kinase C*  / complex / reaction
 ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53*  / reaction / complex






 

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