ENSG00000188976


Homo sapiens

Features
Gene ID: ENSG00000188976
  
Biological name :NOC2L
  
Synonyms : NOC2L / NOC2 like nucleolar associated transcriptional repressor / Q9Y3T9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.33
Gene start: 944204
Gene end: 959309
  
Corresponding Affymetrix probe sets: 1559139_at (Human Genome U133 Plus 2.0 Array)   202115_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000317992
NCBI entrez gene - 26155     See in Manteia.
OMIM - 610770
RefSeq - NM_015658
RefSeq Peptide - NP_056473
swissprot - Q9Y3T9
Ensembl - ENSG00000188976
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 noc2lENSDARG00000001754Danio rerio
 NOC2LENSGALG00000002222Gallus gallus
 Noc2lENSMUSG00000095567Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005343  Nucleolar complex protein 2
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0002903 negative regulation of B cell apoptotic process IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0031497 chromatin assembly IDA
 biological_processGO:0034644 cellular response to UV IDA
 biological_processGO:0035067 negative regulation of histone acetylation IDA
 biological_processGO:0042273 ribosomal large subunit biogenesis IBA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0030690 Noc1p-Noc2p complex IBA
 cellular_componentGO:0030691 Noc2p-Noc3p complex IBA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003714 transcription corepressor activity IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031491 nucleosome binding IDA
 molecular_functionGO:0042393 histone binding IDA
 molecular_functionGO:0070491 repressing transcription factor binding IDA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000141510 TP53 / P04637 / tumor protein p53  / reaction / complex
 ENSG00000178999 AURKB / Q96GD4 / aurora kinase B  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr