ENSDARG00000038754


Danio rerio

Features
Gene ID: ENSDARG00000038754
  
Biological name :plk3
  
Synonyms : plk3 / polo-like kinase 3 (Drosophila)
  
Possible biological names infered from orthology : polo like kinase 3 / Q9H4B4 / serine/threonine-protein kinase PLK3 isoform 2
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 35603637
Gene end: 35611789
  
Corresponding Affymetrix probe sets: Dr.2155.1.S1_at (Zebrafish Array)   NM_201308_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000121537
NCBI entrez gene - 334202     See in Manteia.
RefSeq - NM_201308
RefSeq Peptide - NP_958465
swissprot - B0S6K2
ZFIN ID - ZDB-GENE-030131-6134
Ensembl - ENSDARG00000038754
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLK3ENSGALG00000010129Gallus gallus
 PLK3ENSG00000173846Homo sapiens
 Plk3ENSMUSG00000028680Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
plk2a / polo-like kinase 2a (Drosophila) / PLK2* / Q9NYY3* / polo like kinase 2*ENSDARG0000009075250
plk2b / polo-like kinase 2b (Drosophila) / PLK2* / Q9NYY3* / P53351* / polo like kinase 2* / Serine/threonine-protein kinase PLK2 *ENSDARG0000001913049
plk1 / polo-like kinase 1 (Drosophila) / P53350* / Q07832* / polo like kinase 1*ENSDARG0000005847134
plk4 / polo-like kinase 4 (Drosophila) / Q64702* / O00444* / polo like kinase 4* / Serine/threonine-protein kinase PLK4 *ENSDARG0000000457623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000959  POLO box domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR020658  Serine/threonine-protein kinase Plk3
 IPR033695  Second polo-box domain
 IPR033701  First polo-box domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53*  / reaction






 

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