ENSDARG00000090752


Danio rerio

Features
Gene ID: ENSDARG00000090752
  
Biological name :plk2a
  
Synonyms : plk2a / polo-like kinase 2a (Drosophila)
  
Possible biological names infered from orthology : P53351 / PLK2 / polo like kinase 2 / Q9NYY3 / Serine/threonine-protein kinase PLK2
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 4499943
Gene end: 4508530
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000109716
swissprot - E7EXD4
ZFIN ID - ZDB-GENE-060810-71
Ensembl - ENSDARG00000090752
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLK2ENSGALG00000014725Gallus gallus
 PLK2ENSG00000145632Homo sapiens
 Plk2ENSMUSG00000021701Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
plk2b / polo-like kinase 2b (Drosophila) / PLK2* / Q9NYY3* / P53351* / polo like kinase 2* / Serine/threonine-protein kinase PLK2 *ENSDARG0000001913070
plk3 / polo-like kinase 3 (Drosophila) / Q9H4B4* / polo like kinase 3* / serine/threonine-protein kinase PLK3 isoform 2 *ENSDARG0000003875449
plk1 / polo-like kinase 1 (Drosophila) / P53350* / Q07832* / polo like kinase 1*ENSDARG0000005847132
plk4 / polo-like kinase 4 (Drosophila) / Q64702* / O00444* / polo like kinase 4* / Serine/threonine-protein kinase PLK4 *ENSDARG0000000457621


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000959  POLO box domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR033695  Second polo-box domain
 IPR033701  First polo-box domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000014329 npm1a / nucleophosmin 1a / NPM1* / Q61937* / P06748* / nucleophosmin 1*  / reaction
 ENSDARG00000018121 cenpj / centromere protein J / Q569L8* / Q9HC77*  / reaction






 

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