ENSDARG00000054858


Danio rerio

Features
Gene ID: ENSDARG00000054858
  
Biological name :tp53bp2b
  
Synonyms : tp53bp2b / tumor protein p53 binding protein, 2b
  
Possible biological names infered from orthology : Q13625 / TP53BP2 / transformation related protein 53 binding protein 2 / Trp53bp2 / tumor protein p53 binding protein 2
  
Species: Danio rerio
  
Chr. number: 22
Strand: 1
Band:
Gene start: 28803739
Gene end: 28849279
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000110949
Ensembl peptide - ENSDARP00000118842
Ensembl peptide - ENSDARP00000150072
NCBI entrez gene - 568138     See in Manteia.
NCBI entrez gene - 793439     See in Manteia.
RefSeq - NM_001109770
RefSeq - NM_001045153
RefSeq - XM_005161809
RefSeq - XM_009296445
RefSeq Peptide - NP_001103240
RefSeq Peptide - NP_001038618
swissprot - Q1LXN7
swissprot - F1QWN1
ZFIN ID - ZDB-GENE-050208-453
Ensembl - ENSDARG00000054858
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TP53BP2ENSGALG00000042816Gallus gallus
 Q13625ENSG00000143514Homo sapiens
 Trp53bp2ENSMUSG00000026510Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tp53bp2a / tumor protein p53 binding protein, 2a / Q13625* / TP53BP2* / Trp53bp2* / tumor protein p53 binding protein 2* / transformation related protein 53 binding protein 2*ENSDARG0000000913660
ppp1r13bb / protein phosphatase 1, regulatory subunit 13Bb / Q96KQ4* / Q62415* / PPP1R13B* / protein phosphatase 1 regulatory subunit 13B* / protein phosphatase 1, regulatory (inhibitor) subunit 13B*ENSDARG0000000914244
ppp1r13ba / protein phosphatase 1, regulatory subunit 13Ba / Q96KQ4* / Q62415* / PPP1R13B* / protein phosphatase 1 regulatory subunit 13B* / protein phosphatase 1, regulatory (inhibitor) subunit 13B*ENSDARG0000000437743
ppp1r13l / protein phosphatase 1, regulatory subunit 13 like / Q5I1X5* / Q8WUF5* / protein phosphatase 1, regulatory (inhibitor) subunit 13 like*ENSDARG0000001377717
ppp1r12a / protein phosphatase 1, regulatory subunit 12A / O14974* / Q9DBR7* / protein phosphatase 1, regulatory (inhibitor) subunit 12A*ENSDARG0000001078411
ppp1r12c / protein phosphatase 1, regulatory subunit 12C / Q9BZL4*ENSDARG000000524238
ppp1r16a / protein phosphatase 1, regulatory subunit 16A / Q923M0* / Q96I34* / protein phosphatase 1, regulatory (inhibitor) subunit 16A*ENSDARG000000769807
ppp1r16b / protein phosphatase 1, regulatory subunit 16B / Q8VHQ3* / Q96T49* / protein phosphatase 1, regulatory (inhibitor) subunit 16B*ENSDARG000000798605
CU693479.1 / Q86WC6* / PPP1R27* / protein phosphatase 1 regulatory subunit 27*ENSDARG000001168063
BX323087.1 / O60237* / PPP1R12B* / protein phosphatase 1 regulatory subunit 12B*ENSDARG000001171552
nrarpb / Q7T3X9 / NOTCH regulated ankyrin repeat protein bENSDARG000000189582
ppp1r27b / protein phosphatase 1, regulatory subunit 27b / Q9D119* / Q86WC6* / PPP1R27* / protein phosphatase 1 regulatory subunit 27*ENSDARG000001005042
CABZ01068600.1ENSDARG000001134542
Q7T3Y0 / nrarpa / NOTCH regulated ankyrin repeat protein a / NRARP* / Q7Z6K4* / Q91ZA8* / NOTCH regulated ankyrin repeat protein* / Notch-regulated ankyrin repeat-containing protein *ENSDARG000000914191


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR001452  SH3 domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003341 cilium movement IMP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0051898 negative regulation of protein kinase B signaling IMP
 cellular_componentGO:0005737 cytoplasm IDA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Association with Co-factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle cilium movement decreased frequency , abnormal
Kupffers vesicle motile cilium decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis curved , abnormal
Show

 ZFA:0001261 ventricular system ventricular system hydrocephalic , abnormal
Show

 ZFA:0001617 otolith otolith morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53*  / reaction / complex
 ENSDARG00000017953 tp73 / tumor protein p73 / Trp73* / Q9JJP2* / O15350* / transformation related protein 73*  / complex / reaction






 

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