ENSDARG00000094646


Danio rerio

Features
Gene ID: ENSDARG00000094646
  
Biological name :dyrk2
  
Synonyms : dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 / dyrk2
  
Possible biological names infered from orthology : dual specificity tyrosine phosphorylation regulated kinase 2 / Q5U4C9 / Q92630
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 13449775
Gene end: 13462784
  
Corresponding Affymetrix probe sets: Dr.25303.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000140216
Ensembl peptide - ENSDARP00000122944
Ensembl peptide - ENSDARP00000149505
NCBI entrez gene - 557602     See in Manteia.
swissprot - A0A0R4ITS5
swissprot - Q5RHV3
ZFIN ID - ZDB-GENE-030131-2804
Ensembl - ENSDARG00000094646
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DYRK2ENSGALG00000009901Gallus gallus
 DYRK2ENSG00000127334Homo sapiens
 Dyrk2ENSMUSG00000028630Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DYRK3 / zgc:172180 / O43781* / Q922Y0* / dual specificity tyrosine phosphorylation regulated kinase 3*ENSDARG0000007060065
dyrk4 / dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 / Q8BI55* / Q9NR20* / AC005832.4* / dual specificity tyrosine phosphorylation regulated kinase 4*ENSDARG0000007073441
dyrk1b / dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B / Q9Y463* / Q9Z188* / dual specificity tyrosine phosphorylation regulated kinase 1B*ENSDARG0000007018728
dyrk1aa / dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, aENSDARG0000006357028
dyrk1ab / dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b / Q61214* / DYRK1A* / Q13627* / dual specificity tyrosine phosphorylation regulated kinase 1A* / Mus musculus ...ENSDARG0000002381427
hipk1a / homeodomain interacting protein kinase 1a / HIPK1* / Q86Z02* / O88904* / homeodomain interacting protein kinase 1*ENSDARG0000006359426
hipk3b / homeodomain interacting protein kinase 3b / HIPK3* / Q9H422* / Q9ERH7* / homeodomain interacting protein kinase 3*ENSDARG0000006208226
hipk3a / homeodomain interacting protein kinase 3a / HIPK3* / Q9H422* / Q9ERH7* / homeodomain interacting protein kinase 3*ENSDARG0000006246926
hipk2 / homeodomain interacting protein kinase 2ENSDARG0000004251826
si:ch211-160o17.4 / HIPK1* / O88904* / Q86Z02* / homeodomain interacting protein kinase 1*ENSDARG0000007709525


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron displaced to spinal cord axis, abnormal
Show

 ZFA:0009165 neural crest cell neural crest cell displaced to spinal cord lateral margin, abnormal
Show

 ZFA:0009243 CaP motoneuron CaP motoneuron mislocalised , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000002385 atm / ATM serine/threonine kinase / Q13315* / Q62388* / Serine-protein kinase ATM *  / reaction
 ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53*  / reaction






 

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