ENSDARG00000070187


Danio rerio

Features
Gene ID: ENSDARG00000070187
  
Biological name :dyrk1b
  
Synonyms : dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B / dyrk1b
  
Possible biological names infered from orthology : dual specificity tyrosine phosphorylation regulated kinase 1B / Q9Y463 / Q9Z188
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 42071696
Gene end: 42152145
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000030868
Ensembl peptide - ENSDARP00000135231
NCBI entrez gene - 556212     See in Manteia.
RefSeq - NM_001168265
RefSeq Peptide - NP_001161737
swissprot - D1L3Y5
swissprot - A0A0R4II39
ZFIN ID - ZDB-GENE-060503-499
Ensembl - ENSDARG00000070187
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DYRK1BENSG00000105204Homo sapiens
 Dyrk1bENSMUSG00000002409Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dyrk1ab / dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b / Q61214* / DYRK1A* / Q13627* / dual specificity tyrosine phosphorylation regulated kinase 1A* / Mus musculus ...ENSDARG0000002381461
dyrk1aa / dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, aENSDARG0000006357060
hipk2 / homeodomain interacting protein kinase 2ENSDARG0000004251824
hipk1a / homeodomain interacting protein kinase 1a / HIPK1* / Q86Z02* / O88904* / homeodomain interacting protein kinase 1*ENSDARG0000006359423
dyrk4 / dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 / Q8BI55* / Q9NR20* / AC005832.4* / dual specificity tyrosine phosphorylation regulated kinase 4*ENSDARG0000007073423
DYRK3 / zgc:172180 / O43781* / Q922Y0* / dual specificity tyrosine phosphorylation regulated kinase 3*ENSDARG0000007060023
hipk3a / homeodomain interacting protein kinase 3a / HIPK3* / Q9H422* / Q9ERH7* / homeodomain interacting protein kinase 3*ENSDARG0000006246922
hipk3b / homeodomain interacting protein kinase 3b / HIPK3* / Q9H422* / Q9ERH7* / homeodomain interacting protein kinase 3*ENSDARG0000006208222
dyrk2 / dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 / Q5U4C9* / Q92630* / dual specificity tyrosine phosphorylation regulated kinase 2*ENSDARG0000009464622
si:ch211-160o17.4 / HIPK1* / O88904* / Q86Z02* / homeodomain interacting protein kinase 1*ENSDARG0000007709521


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR033565  Dual specificity tyrosine-phosphorylation-regulated kinase 1B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001706 endoderm formation IMP
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000017 endoderm endoderm decreased amount , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000114 heart heart physical object quality , abnormal
heart bilateral symmetry , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
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 ZFA:0001306 pharyngeal arch pharyngeal arch physical object quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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