ENSGALG00000009901


Gallus gallus

Features
Gene ID: ENSGALG00000009901
  
Biological name :DYRK2
  
Synonyms : Dual specificity tyrosine-phosphorylation-regulated kinase 2 / DYRK2 / Q5ZIU3
  
Possible biological names infered from orthology : Q5U4C9 / Q92630
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 34899306
Gene end: 34909399
  
Corresponding Affymetrix probe sets: Gga.14403.1.S1_at (Chicken Array)   Gga.14403.1.S1_s_at (Chicken Array)   GgaAffx.12794.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000016084
NCBI entrez gene - 427864     See in Manteia.
RefSeq - XM_015281985
RefSeq - NM_001031480
RefSeq - XM_015281990
RefSeq Peptide - NP_001026651
swissprot - Q5ZIU3
Ensembl - ENSGALG00000009901
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dyrk2ENSDARG00000094646Danio rerio
 DYRK2ENSG00000127334Homo sapiens
 Dyrk2ENSMUSG00000028630Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DYRK3 / dual specificity tyrosine phosphorylation regulated kinase 3 / O43781* / Q922Y0*ENSGALG0000000086370
DYRK1A / dual specificity tyrosine-phosphorylation-regulated kinase 1A / Q13627* / Q61214* / Mus musculus dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a (Dyrk1a), transc...ENSGALG0000001605331
HIPK3 / homeodomain-interacting protein kinase 3 / Q9ERH7* / Q9H422*ENSGALG0000001169528
HIPK2 / homeodomain interacting protein kinase 2 / Q9H2X6* / Q9QZR5*ENSGALG0000001279228
HIPK1 / homeodomain interacting protein kinase 1 / O88904* / Q86Z02*ENSGALG0000000193927


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation ISS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007224 smoothened signaling pathway IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
 biological_processGO:0045725 positive regulation of glycogen biosynthetic process IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISS
 molecular_functionGO:0004712 protein serine/threonine/tyrosine kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity ISS
 molecular_functionGO:0005524 ATP binding ISS
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030145 manganese ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000017159 ATM / ATM serine/threonine kinase / Q13315* / Q62388* / Serine-protein kinase ATM *  / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction






 

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