ENSDARG00000067817


Danio rerio

Features
Gene ID: ENSDARG00000067817
  
Biological name :CABZ01083448.1
  
Synonyms : CABZ01083448.1
  
Possible biological names infered from orthology : O43741 / PRKAB2 / protein kinase, AMP-activated, beta 2 non-catalytic subunit / protein kinase AMP-activated non-catalytic subunit beta 2 / Q6PAM0
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 58739111
Gene end: 58742863
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000088460
swissprot - E7F9H4
Ensembl - ENSDARG00000067817
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRKAB2ENSGALG00000001678Gallus gallus
 O43741ENSG00000131791Homo sapiens
 Prkab2ENSMUSG00000038205Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prkab1a / protein kinase, AMP-activated, beta 1 non-catalytic subunit, a / PRKAB1* / Q9R078* / Q9Y478* / protein kinase AMP-activated non-catalytic subunit beta 1* / protein kinase, AMP-act...ENSDARG0000004418350
prkab1b / protein kinase, AMP-activated, beta 1 non-catalytic subunit, b / PRKAB1* / Q9R078* / Q9Y478* / protein kinase AMP-activated non-catalytic subunit beta 1* / protein kinase, AMP-act...ENSDARG0000004614348


Protein motifs (from Interpro)
Interpro ID Name
 IPR006828  Association with the SNF1 complex (ASC) domain
 IPR013783  Immunoglobulin-like fold
 IPR014756  Immunoglobulin E-set
 IPR032640  AMP-activated protein kinase, glycogen-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
Macroautophagy
AMPK inhibits chREBP transcriptional activation activity
Import of palmitoyl-CoA into the mitochondrial matrix
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of TP53 Activity through Phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000017537 prkag3a / protein kinase, AMP-activated, gamma 3a non-catalytic subunit / Q9UGI9* / PRKAG3* / Q8BGM7* / protein kinase AMP-activated non-catalytic subunit gamma 3* / protein kinase, AMP-act...  / complex
 ENSDARG00000003818 prkag1 / protein kinase, AMP-activated, gamma 1 non-catalytic subunit / O54950* / P54619* / protein kinase AMP-activated non-catalytic subunit gamma 1*  / complex
 ENSDARG00000036040 atg13 / Q7SYE0 / ATG13 autophagy related 13 homolog (S. cerevisiae) / Q91YI1* / O75143* / autophagy related 13* / Mus musculus autophagy related 13 (Atg13), transcript variant 4, mRNA.*  / reaction / complex
 ENSDARG00000043287 atg101 / Q3B736 / autophagy related 101 / Q9BSB4* / Q9D8Z6* / Autophagy-related protein 101 *  / reaction / complex
 ENSDARG00000060641 prkaa2 / protein kinase, AMP-activated, alpha 2 catalytic subunit / P54646* / protein kinase AMP-activated catalytic subunit alpha 2*  / complex
 ENSDARG00000076559 rb1cc1 / RB1-inducible coiled-coil 1 / Q8TDY2*  / reaction / complex
 ENSDARG00000054829 pik3c3 / phosphatidylinositol 3-kinase, catalytic subunit type 3 / Q6PF93* / Q8NEB9*  / reaction
 ENSDARG00000069790 dynll2a / dynein, light chain, LC8-type 2a / Q9D0M5* / DYNLL2* / Q96FJ2* / dynein light chain LC8-type 2* / Dynein light chain 2, cytoplasmic *  / reaction
 ENSDARG00000074481 ulk1b / unc-51 like autophagy activating kinase 1 / ULK1* / O75385* / unc-51 like kinase 1*  / reaction / complex
 ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53*  / reaction
 ENSDARG00000000369 prkag3b / protein kinase, AMP-activated, gamma 3b non-catalytic subunit / Q9UGI9* / PRKAG3* / Q8BGM7* / protein kinase AMP-activated non-catalytic subunit gamma 3* / protein kinase, AMP-act...  / complex
 ENSDARG00000020693 sesn1 / sestrin 1 / P58006* / Q9Y6P5*  / complex / reaction
 ENSDARG00000058454 dynll1 / dynein, light chain, LC8-type 1 / P63168* / P63167* / BC048507* / cDNA sequence BC048507* / Dynein light chain 1, cytoplasmic *  / reaction
 ENSDARG00000098726 rptor / regulatory associated protein of MTOR, complex 1 / Q8N122*  / reaction
 ENSDARG00000032769 Q08BA4 / slc38a9 / solute carrier family 38, member 9 / Q8NBW4*  / reaction
 ENSDARG00000002670 ATG14 / zgc:113944 / Q6ZNE5* / Q8CDJ3* / autophagy related 14* / Beclin 1-associated autophagy-related key regulator *  / reaction
 ENSDARG00000079128 becn1 / F1RCP1 / beclin 1, autophagy related / BECN2* / Q14457* / O88597* / P0DM65* / A8MW95* / Gm38100* / beclin 2* / beclin 1* / Beclin-1 Beclin-1-C 35 kDa Beclin-1-C 37 kDa*  / reaction
 ENSDARG00000060469 pik3r4 / phosphoinositide-3-kinase, regulatory subunit 4 / Q8VD65* / Q99570*  / reaction
 ENSDARG00000070012 sesn2 / sestrin 2 / P58004* / P58043*  / complex / reaction
 ENSDARG00000060596 prkaa1 / protein kinase, AMP-activated, alpha 1 catalytic subunit / Q13131* / Q5EG47* / protein kinase AMP-activated catalytic subunit alpha 1*  / complex
 ENSDARG00000003167 mlst8 / Q803V5 / MTOR associated protein, LST8 homolog (S. cerevisiae) / Q9BVC4* / Q9DCJ1* / MTOR associated protein, LST8 homolog* / Target of rapamycin complex subunit LST8 *  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr