ENSDARG00000076559


Danio rerio

Features
Gene ID: ENSDARG00000076559
  
Biological name :rb1cc1
  
Synonyms : rb1cc1 / RB1-inducible coiled-coil 1
  
Possible biological names infered from orthology : Q8TDY2 / Q9ESK9 / RB1-inducible coiled-coil protein 1
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 34970680
Gene end: 35003375
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000097746
NCBI entrez gene - 100332174     See in Manteia.
swissprot - E7FFM2
ZFIN ID - ZDB-GENE-130206-1
Ensembl - ENSDARG00000076559
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RB1CC1ENSGALG00000015259Gallus gallus
 Q8TDY2ENSG00000023287Homo sapiens
 Q9ESK9ENSMUSG00000025907Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019460  Autophagy-related protein 11


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IBA
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0001934 positive regulation of protein phosphorylation IBA
 biological_processGO:0030242 autophagy of peroxisome IBA
 biological_processGO:0061709 reticulophagy IBA
 biological_processGO:0061723 glycophagy IBA
 cellular_componentGO:0034045 phagophore assembly site membrane IBA
 cellular_componentGO:1990316 Atg1/ULK1 kinase complex IBA
 molecular_functionGO:0019901 protein kinase binding IBA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IBA


Pathways (from Reactome)
Pathway description
Macroautophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000035 lens lens autophagy decreased frequency , abnormal
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 ZFA:0000075 spinal cord spinal cord autophagy decreased frequency , abnormal
Show

 ZFA:0001056 myotome myotome autophagy decreased frequency , abnormal
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 ZFA:0001202 optic cup optic cup autophagy decreased frequency , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003167 mlst8 / Q803V5 / MTOR associated protein, LST8 homolog (S. cerevisiae) / Q9BVC4* / Q9DCJ1* / MTOR associated protein, LST8 homolog* / Target of rapamycin complex subunit LST8 *  / complex / reaction
 ENSDARG00000017537 prkag3a / protein kinase, AMP-activated, gamma 3a non-catalytic subunit / Q9UGI9* / PRKAG3* / Q8BGM7* / protein kinase AMP-activated non-catalytic subunit gamma 3* / protein kinase, AMP-act...  / reaction / complex
 ENSDARG00000003818 prkag1 / protein kinase, AMP-activated, gamma 1 non-catalytic subunit / O54950* / P54619* / protein kinase AMP-activated non-catalytic subunit gamma 1*  / reaction / complex
 ENSDARG00000032769 Q08BA4 / slc38a9 / solute carrier family 38, member 9 / Q8NBW4*  / complex / reaction
 ENSDARG00000046143 prkab1b / protein kinase, AMP-activated, beta 1 non-catalytic subunit, b / PRKAB1* / Q9R078* / Q9Y478* / protein kinase AMP-activated non-catalytic subunit beta 1* / protein kinase, AMP-act...  / reaction / complex
 ENSDARG00000036040 atg13 / Q7SYE0 / ATG13 autophagy related 13 homolog (S. cerevisiae) / Q91YI1* / O75143* / autophagy related 13* / Mus musculus autophagy related 13 (Atg13), transcript variant 4, mRNA.*  / complex
 ENSDARG00000060596 prkaa1 / protein kinase, AMP-activated, alpha 1 catalytic subunit / Q13131* / Q5EG47* / protein kinase AMP-activated catalytic subunit alpha 1*  / reaction / complex
 ENSDARG00000043287 atg101 / Q3B736 / autophagy related 101 / Q9BSB4* / Q9D8Z6* / Autophagy-related protein 101 *  / complex
 ENSDARG00000060641 prkaa2 / protein kinase, AMP-activated, alpha 2 catalytic subunit / P54646* / protein kinase AMP-activated catalytic subunit alpha 2*  / reaction / complex
 ENSDARG00000044183 prkab1a / protein kinase, AMP-activated, beta 1 non-catalytic subunit, a / PRKAB1* / Q9R078* / Q9Y478* / protein kinase AMP-activated non-catalytic subunit beta 1* / protein kinase, AMP-act...  / reaction / complex
 ENSDARG00000000369 prkag3b / protein kinase, AMP-activated, gamma 3b non-catalytic subunit / Q9UGI9* / PRKAG3* / Q8BGM7* / protein kinase AMP-activated non-catalytic subunit gamma 3* / protein kinase, AMP-act...  / reaction / complex
 ENSDARG00000058454 dynll1 / dynein, light chain, LC8-type 1 / P63168* / P63167* / BC048507* / cDNA sequence BC048507* / Dynein light chain 1, cytoplasmic *  / reaction
 ENSDARG00000054829 pik3c3 / phosphatidylinositol 3-kinase, catalytic subunit type 3 / Q6PF93* / Q8NEB9*  / reaction
 ENSDARG00000074481 ulk1b / unc-51 like autophagy activating kinase 1 / ULK1* / O75385* / unc-51 like kinase 1*  / complex
 ENSDARG00000069790 dynll2a / dynein, light chain, LC8-type 2a / Q9D0M5* / DYNLL2* / Q96FJ2* / dynein light chain LC8-type 2* / Dynein light chain 2, cytoplasmic *  / reaction
 ENSDARG00000067817 CABZ01083448.1 / O43741* / PRKAB2* / protein kinase AMP-activated non-catalytic subunit beta 2*  / reaction / complex
 ENSDARG00000002670 ATG14 / zgc:113944 / Q6ZNE5* / Q8CDJ3* / autophagy related 14* / Beclin 1-associated autophagy-related key regulator *  / reaction
 ENSDARG00000098726 rptor / regulatory associated protein of MTOR, complex 1 / Q8N122*  / reaction / complex
 ENSDARG00000079128 becn1 / F1RCP1 / beclin 1, autophagy related / BECN2* / Q14457* / O88597* / P0DM65* / A8MW95* / Gm38100* / beclin 2* / beclin 1* / Beclin-1 Beclin-1-C 35 kDa Beclin-1-C 37 kDa*  / reaction
 ENSDARG00000060469 pik3r4 / phosphoinositide-3-kinase, regulatory subunit 4 / Q8VD65* / Q99570*  / reaction






 

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