ENSGALG00000001678


Gallus gallus

Features
Gene ID: ENSGALG00000001678
  
Biological name :PRKAB2
  
Synonyms : PRKAB2 / protein kinase AMP-activated non-catalytic subunit beta 2
  
Possible biological names infered from orthology : O43741 / protein kinase, AMP-activated, beta 2 non-catalytic subunit / Q6PAM0
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 4300210
Gene end: 4334287
  
Corresponding Affymetrix probe sets: Gga.8821.1.S1_at (Chicken Array)   GgaAffx.1098.1.S1_s_at (Chicken Array)   GgaAffx.24813.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000002564
Ensembl peptide - ENSGALP00000052141
Ensembl peptide - ENSGALP00000061225
Ensembl peptide - ENSGALP00000064204
NCBI entrez gene - 427017     See in Manteia.
RefSeq - XM_015290315
RefSeq - NM_001044662
RefSeq - XM_015290312
RefSeq - XM_015290313
RefSeq - XM_015290314
RefSeq - XM_015290310
RefSeq - XM_015290311
RefSeq Peptide - NP_001038127
swissprot - Q156C5
swissprot - Q156C7
Ensembl - ENSGALG00000001678
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01083448.1ENSDARG00000067817Danio rerio
 O43741ENSG00000131791Homo sapiens
 Prkab2ENSMUSG00000038205Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRKAB1 / Q9R078* / Q9Y478* / protein kinase AMP-activated non-catalytic subunit beta 1* / protein kinase, AMP-activated, beta 1 non-catalytic subunit*ENSGALG0000000737370


Protein motifs (from Interpro)
Interpro ID Name
 IPR006828  Association with the SNF1 complex (ASC) domain
 IPR014756  Immunoglobulin E-set
 IPR032640  AMP-activated protein kinase, glycogen-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016310 phosphorylation IEA
 cellular_componentGO:0031588 nucleotide-activated protein kinase complex IEA
 molecular_functionGO:0004679 AMP-activated protein kinase activity IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Macroautophagy
AMPK inhibits chREBP transcriptional activation activity
Import of palmitoyl-CoA into the mitochondrial matrix
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008347 ATG13 / autophagy related 13 / O75143* / Q91YI1* / Mus musculus autophagy related 13 (Atg13), transcript variant 4, mRNA.*  / complex / reaction
 ENSGALG00000003339 MTOR / mechanistic target of rapamycin kinase / P42345* / Q9JLN9* / Serine/threonine-protein kinase mTOR *  / reaction
 ENSGALG00000014712 SLC38A9 / solute carrier family 38 member 9 / Q8BGD6* / Q8NBW4* / Sodium-coupled neutral amino acid transporter 9 *  / reaction
 ENSGALG00000012148 ATG14 / autophagy related 14 / Q6ZNE5* / Q8CDJ3* / Beclin 1-associated autophagy-related key regulator *  / reaction
 ENSGALG00000005646 TSC2 / TSC complex subunit 2 / P49815* / tuberous sclerosis 2*  / reaction
 ENSGALG00000026971 RRAGD / Ras related GTP binding D / Q9NQL2*  / reaction
 ENSGALG00000041226 RRAGB* / RRAGA* / Q7L523* / Q80X95* / Q5VZM2* / Q6NTA4* / Ras related GTP binding A* / Ras related GTP binding B* / Ras-related GTP-binding protein A * / Ras-related GTP-binding protein B *  / reaction
 ENSGALG00000020999 DYNLL1 / dynein light chain LC8-type 1 / P63168* / P63167* / BC048507* / cDNA sequence BC048507* / Dynein light chain 1, cytoplasmic *  / reaction
 ENSGALG00000010826 PRKAA2 / protein kinase AMP-activated catalytic subunit alpha 2 / P54646* / Q8BRK8* / protein kinase, AMP-activated, alpha 2 catalytic subunit*  / complex
 ENSGALG00000005878 MLST8 / MTOR associated protein, LST8 homolog / Q9BVC4* / Q9DCJ1* / Target of rapamycin complex subunit LST8 *  / reaction
 ENSGALG00000005522 DYNLL2 / dynein light chain LC8-type 2 / Q96FJ2* / Q9D0M5* / Dynein light chain 2, cytoplasmic *  / reaction
 ENSGALG00000015259 RB1CC1 / RB1 inducible coiled-coil 1 / Q8TDY2* / Q9ESK9* / RB1-inducible coiled-coil protein 1 *  / complex / reaction
 ENSGALG00000035773 PIK3C3 / phosphatidylinositol 3-kinase catalytic subunit type 3 / Q6PF93* / Q8NEB9*  / reaction
 ENSGALG00000014832 PRKAA1 / protein kinase AMP-activated catalytic subunit alpha 1 / Q13131* / Q5EG47* / protein kinase, AMP-activated, alpha 1 catalytic subunit*  / complex
 ENSGALG00000011917 PPM1A / protein phosphatase, Mg2+/Mn2+ dependent 1A / P35813* / P49443* / protein phosphatase 1A, magnesium dependent, alpha isoform*  / reaction
 ENSGALG00000011360 PRKAG3 / 5-AMP-activated protein kinase subunit gamma-3 / Q9UGI9* / Q8BGM7* / protein kinase AMP-activated non-catalytic subunit gamma 3* / protein kinase, AMP-activated, gamma 3 non-catat...  / complex
 ENSGALG00000036282 O54950* / P54619* / PRKAG1* / protein kinase AMP-activated non-catalytic subunit gamma 1* / protein kinase, AMP-activated, gamma 1 non-catalytic subunit*  / complex
 ENSGALG00000040008 STK11 / Q0GGW5 / Serine/threonine-protein kinase STK11 / Q9WTK7* / Q15831* / serine/threonine kinase 11*  / reaction






 

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