ENSGALG00000005522


Gallus gallus

Features
Gene ID: ENSGALG00000005522
  
Biological name :DYNLL2
  
Synonyms : dynein light chain LC8-type 2 / DYNLL2
  
Possible biological names infered from orthology : Dynein light chain 2, cytoplasmic / Q96FJ2 / Q9D0M5
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 8712740
Gene end: 8719340
  
Corresponding Affymetrix probe sets: Gga.17308.1.S1_s_at (Chicken Array)   Gga.3112.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000008845
NCBI entrez gene - 417663     See in Manteia.
RefSeq - NM_001302156
RefSeq Peptide - NP_001289085
swissprot - F1NRI4
Ensembl - ENSGALG00000005522
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dynll2aENSDARG00000069790Danio rerio
 dynll2bENSDARG00000005172Danio rerio
 DYNLL2ENSG00000264364Homo sapiens
 Dynll2ENSMUSG00000020483Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DYL1ENSGALG0000000715396
DYNLL1 / dynein light chain LC8-type 1 / P63168* / P63167* / BC048507* / cDNA sequence BC048507* / Dynein light chain 1, cytoplasmic *ENSGALG0000002099994
ENSGALG0000004086964
ENSGALG0000000714762
DNAL4 / dynein axonemal light chain 4 / O96015* / Q9DCM4* / Dynein light chain 4, axonemal *ENSGALG0000004345135


Protein motifs (from Interpro)
Interpro ID Name
 IPR001372  Dynein light chain, type 1/2
 IPR019763  Dynein light chain, type 1/2, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007017 microtubule-based process IEA
 biological_processGO:0010970 transport along microtubule IBA
 biological_processGO:0060271 cilium assembly IBA
 biological_processGO:2000582 positive regulation of ATP-dependent microtubule motor activity, plus-end-directed IBA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005868 cytoplasmic dynein complex IEA
 cellular_componentGO:0005875 microtubule associated complex IEA
 cellular_componentGO:0016459 myosin complex IBA
 cellular_componentGO:0030286 dynein complex IEA
 cellular_componentGO:0031475 myosin V complex IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IBA
 molecular_functionGO:0008574 ATP-dependent microtubule motor activity, plus-end-directed IBA
 molecular_functionGO:0045505 dynein intermediate chain binding IBA
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
Activation of BMF and translocation to mitochondria
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Macroautophagy
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Intraflagellar transport
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001547 P13127 / CAPZA1 / F-actin-capping protein subunit alpha-1 / P52907* / 4933400A11Rik* / RIKEN cDNA 4933400A11 gene* / capping actin protein of muscle Z-line alpha subunit 1*  / complex
 ENSGALG00000001678 PRKAB2 / protein kinase AMP-activated non-catalytic subunit beta 2 / O43741* / Q6PAM0* / protein kinase, AMP-activated, beta 2 non-catalytic subunit*  / reaction
 ENSGALG00000004034 CAPZB / P14315 / F-actin-capping protein subunit beta isoforms 1 and 2 / P47757* / P47756* / F-actin-capping protein subunit beta * / capping actin protein of muscle Z-line beta subunit*  / complex
 ENSGALG00000004534 DCTN4 / dynactin subunit 4 / Q8CBY8* / Q9UJW0* / Mus musculus dynactin 4 (Dctn4), transcript variant 2, mRNA.*  / complex
 ENSGALG00000008086 ACTR1A / ARP1 actin related protein 1 homolog A / P61163* / P61164* / Alpha-centractin *  / complex
 ENSGALG00000006109 MAPK8 / mitogen-activated protein kinase 8 / P45983* / Q91Y86*  / reaction
 ENSGALG00000011106 GALNT2 / polypeptide N-acetylgalactosaminyltransferase 2 / Q6PB93* / Q10471* / Gm20388* / predicted gene 20388* / Polypeptide N-acetylgalactosaminyltransferase 2 Polypeptide N-acetylgalacto...  / complex / reaction
 ENSGALG00000005522 DYNLL2 / dynein light chain LC8-type 2 / Q96FJ2* / Q9D0M5* / Dynein light chain 2, cytoplasmic *  / complex
 ENSGALG00000012148 ATG14 / autophagy related 14 / Q6ZNE5* / Q8CDJ3* / Beclin 1-associated autophagy-related key regulator *  / complex / reaction
 ENSGALG00000013135 GALNT1 / polypeptide N-acetylgalactosaminyltransferase 1 / O08912* / Q10472* / Polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase 1 soluble form*  / complex / reaction
 ENSGALG00000017320 RAB6A / Q1KME6 / Ras-related protein Rab-6A / RAB6D* / RAB6C* / Q9H0N0* / P35279* / P20340* / RAB6A, member RAS oncogene family* / RAB6D, member RAS oncogene family* / RAB6C, member RAS on...  / complex / reaction
 ENSGALG00000014537 BMF / bcl-2-modifying factor / Q96LC9* / Mus musculus BCL2 modifying factor (Bmf), transcript variant 3, mRNA.*  / complex
 ENSGALG00000035773 PIK3C3 / phosphatidylinositol 3-kinase catalytic subunit type 3 / Q6PF93* / Q8NEB9*  / reaction / complex
 ENSGALG00000020999 DYNLL1 / dynein light chain LC8-type 1 / P63168* / P63167* / BC048507* / cDNA sequence BC048507* / Dynein light chain 1, cytoplasmic *  / complex
 ENSGALG00000005834 Q9PTR5 / PAFAH1B1 / Lissencephaly-1 homolog / P43034* / P63005* / platelet-activating factor acetylhydrolase, isoform 1b, subunit 1* / platelet activating factor acetylhydrolase 1b regulat...  / complex
 ENSGALG00000006088 DCTN5 / dynactin subunit 5 / Q9BTE1* / Q9QZB9*  / complex
 ENSGALG00000007373 PRKAB1 / Q9R078* / Q9Y478* / protein kinase AMP-activated non-catalytic subunit beta 1* / protein kinase, AMP-activated, beta 1 non-catalytic subunit*  / reaction
 ENSGALG00000005241 DYNC1LI2 / cytoplasmic dynein 1 light intermediate chain 2 / O43237* / Q6PDL0* / dynein cytoplasmic 1 light intermediate chain 2*  / complex
 ENSGALG00000008347 ATG13 / autophagy related 13 / O75143* / Q91YI1* / Mus musculus autophagy related 13 (Atg13), transcript variant 4, mRNA.*  / reaction
 ENSGALG00000015259 RB1CC1 / RB1 inducible coiled-coil 1 / Q8TDY2* / Q9ESK9* / RB1-inducible coiled-coil protein 1 *  / reaction
 ENSGALG00000011491 Q90828 / DYNC1LI1 / Cytoplasmic dynein 1 light intermediate chain 1 / Q8R1Q8* / Q9Y6G9* / dynein cytoplasmic 1 light intermediate chain 1*  / complex
 ENSGALG00000013125 CAPZA3 / capping actin protein of muscle Z-line alpha subunit 3 / P70190* / Q96KX2* / F-actin-capping protein subunit alpha-3 *  / complex
 ENSGALG00000014832 PRKAA1 / protein kinase AMP-activated catalytic subunit alpha 1 / Q13131* / Q5EG47* / protein kinase, AMP-activated, alpha 1 catalytic subunit*  / reaction
 ENSGALG00000021365 DCTN3 / dynactin subunit 3 / O75935* / Q9Z0Y1*  / complex
 ENSGALG00000010298 DCTN6 / dynactin subunit 6 / O00399* / Q9WUB4*  / complex
 ENSGALG00000010826 PRKAA2 / protein kinase AMP-activated catalytic subunit alpha 2 / P54646* / Q8BRK8* / protein kinase, AMP-activated, alpha 2 catalytic subunit*  / reaction
 ENSGALG00000011360 PRKAG3 / 5-AMP-activated protein kinase subunit gamma-3 / Q9UGI9* / Q8BGM7* / protein kinase AMP-activated non-catalytic subunit gamma 3* / protein kinase, AMP-activated, gamma 3 non-catat...  / reaction
 ENSGALG00000043437 P28497 / CAPZA2 / F-actin-capping protein subunit alpha-2 / P47754* / P47755* / capping actin protein of muscle Z-line alpha subunit 2*  / complex
 ENSGALG00000036282 O54950* / P54619* / PRKAG1* / protein kinase AMP-activated non-catalytic subunit gamma 1* / protein kinase, AMP-activated, gamma 1 non-catalytic subunit*  / reaction
 ENSGALG00000011330 DYNC1H1 / dynein cytoplasmic 1 heavy chain 1 / Q14204* / Q9JHU4* / Cytoplasmic dynein 1 heavy chain 1 *  / complex






 

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