ENSGALG00000001547


Gallus gallus

Features
Gene ID: ENSGALG00000001547
  
Biological name :CAPZA1
  
Synonyms : CAPZA1 / F-actin-capping protein subunit alpha-1 / P13127
  
Possible biological names infered from orthology : 4933400A11Rik / capping actin protein of muscle Z-line alpha subunit 1 / P52907 / RIKEN cDNA 4933400A11 gene
  
Species: Gallus gallus
  
Chr. number: 26
Strand: 1
Band:
Gene start: 3532931
Gene end: 3542982
  
Corresponding Affymetrix probe sets: Gga.2783.1.S1_at (Chicken Array)   GgaAffx.11794.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000002349
Ensembl peptide - ENSGALP00000056898
Ensembl peptide - ENSGALP00000053121
NCBI entrez gene - 396521     See in Manteia.
RefSeq - NM_205515
RefSeq Peptide - NP_990846
swissprot - A0A1I7Q3Y4
swissprot - A0A1D5PJX2
swissprot - P13127
Ensembl - ENSGALG00000001547
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 capza1aENSDARG00000034240Danio rerio
 capza1bENSDARG00000056090Danio rerio
 CAPZA1ENSG00000116489Homo sapiens
 4933400A11RikENSMUSG00000055357Mus musculus
 Capza1ENSMUSG00000070372Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P28497 / CAPZA2 / F-actin-capping protein subunit alpha-2 / P47754* / P47755* / capping actin protein of muscle Z-line alpha subunit 2*ENSGALG0000004343781
CAPZA3 / capping actin protein of muscle Z-line alpha subunit 3 / P70190* / Q96KX2* / F-actin-capping protein subunit alpha-3 *ENSGALG0000001312536


Protein motifs (from Interpro)
Interpro ID Name
 IPR002189  F-actin-capping protein subunit alpha
 IPR017865  F-actin capping protein, alpha subunit, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0034329 cell junction assembly IEA
 biological_processGO:0051016 barbed-end actin filament capping IEA
 biological_processGO:0051693 actin filament capping IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0008290 F-actin capping protein complex IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0071203 WASH complex IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
HSP90 chaperone cycle for steroid hormone receptors (SHR)
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Advanced glycosylation endproduct receptor signaling
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000011491 Q90828 / DYNC1LI1 / Cytoplasmic dynein 1 light intermediate chain 1 / Q8R1Q8* / Q9Y6G9* / dynein cytoplasmic 1 light intermediate chain 1*  / complex
 ENSGALG00000011106 GALNT2 / polypeptide N-acetylgalactosaminyltransferase 2 / Q6PB93* / Q10471* / Gm20388* / predicted gene 20388* / Polypeptide N-acetylgalactosaminyltransferase 2 Polypeptide N-acetylgalacto...  / complex / reaction
 ENSGALG00000013135 GALNT1 / polypeptide N-acetylgalactosaminyltransferase 1 / O08912* / Q10472* / Polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase 1 soluble form*  / reaction / complex
 ENSGALG00000005241 DYNC1LI2 / cytoplasmic dynein 1 light intermediate chain 2 / O43237* / Q6PDL0* / dynein cytoplasmic 1 light intermediate chain 2*  / complex
 ENSGALG00000011330 DYNC1H1 / dynein cytoplasmic 1 heavy chain 1 / Q14204* / Q9JHU4* / Cytoplasmic dynein 1 heavy chain 1 *  / complex
 ENSGALG00000020999 DYNLL1 / dynein light chain LC8-type 1 / P63168* / P63167* / BC048507* / cDNA sequence BC048507* / Dynein light chain 1, cytoplasmic *  / complex
 ENSGALG00000005834 Q9PTR5 / PAFAH1B1 / Lissencephaly-1 homolog / P43034* / P63005* / platelet-activating factor acetylhydrolase, isoform 1b, subunit 1* / platelet activating factor acetylhydrolase 1b regulat...  / complex
 ENSGALG00000017320 RAB6A / Q1KME6 / Ras-related protein Rab-6A / RAB6D* / RAB6C* / Q9H0N0* / P35279* / P20340* / RAB6A, member RAS oncogene family* / RAB6D, member RAS oncogene family* / RAB6C, member RAS on...  / reaction / complex
 ENSGALG00000008086 ACTR1A / ARP1 actin related protein 1 homolog A / P61163* / P61164* / Alpha-centractin *  / complex
 ENSGALG00000006217 S100B / S100 calcium binding protein B / P04271* / P50114* / S100 protein, beta polypeptide, neural*  / complex / reaction
 ENSGALG00000021365 DCTN3 / dynactin subunit 3 / O75935* / Q9Z0Y1*  / complex
 ENSGALG00000005522 DYNLL2 / dynein light chain LC8-type 2 / Q96FJ2* / Q9D0M5* / Dynein light chain 2, cytoplasmic *  / complex
 ENSGALG00000004034 CAPZB / P14315 / F-actin-capping protein subunit beta isoforms 1 and 2 / P47757* / P47756* / F-actin-capping protein subunit beta * / capping actin protein of muscle Z-line beta subunit*  / reaction / complex
 ENSGALG00000004534 DCTN4 / dynactin subunit 4 / Q8CBY8* / Q9UJW0* / Mus musculus dynactin 4 (Dctn4), transcript variant 2, mRNA.*  / complex
 ENSGALG00000006088 DCTN5 / dynactin subunit 5 / Q9BTE1* / Q9QZB9*  / complex
 ENSGALG00000010298 DCTN6 / dynactin subunit 6 / O00399* / Q9WUB4*  / complex






 

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