ENSGALG00000004034


Gallus gallus

Features
Gene ID: ENSGALG00000004034
  
Biological name :CAPZB
  
Synonyms : CAPZB / F-actin-capping protein subunit beta isoforms 1 and 2 / P14315
  
Possible biological names infered from orthology : capping actin protein of muscle Z-line beta subunit / F-actin-capping protein subunit beta / P47756 / P47757
  
Species: Gallus gallus
  
Chr. number: 21
Strand: -1
Band:
Gene start: 4679440
Gene end: 4732261
  
Corresponding Affymetrix probe sets: Gga.4050.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047875
Ensembl peptide - ENSGALP00000062411
Ensembl peptide - ENSGALP00000060268
Ensembl peptide - ENSGALP00000049427
Ensembl peptide - ENSGALP00000006414
Ensembl peptide - ENSGALP00000006415
NCBI entrez gene - 396418     See in Manteia.
RefSeq - XM_015296835
RefSeq - NM_001173529
RefSeq - NM_205437
RefSeq Peptide - NP_001167000
RefSeq Peptide - NP_990768
swissprot - P14315
swissprot - A0A1L1RUA9
swissprot - A0A1D5P9M3
swissprot - A0A1D5P5A8
Ensembl - ENSGALG00000004034
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 capzbENSDARG00000100252Danio rerio
 CAPZBENSG00000077549Homo sapiens
 CapzbENSMUSG00000028745Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001698  F-actin-capping protein subunit beta
 IPR019771  F-actin capping protein, beta subunit, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IBA
 biological_processGO:0007010 cytoskeleton organization ISS
 biological_processGO:0010591 regulation of lamellipodium assembly IBA
 biological_processGO:0022604 regulation of cell morphogenesis ISS
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0030032 lamellipodium assembly IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0031115 negative regulation of microtubule polymerization IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0048747 muscle fiber development IEA
 biological_processGO:0051016 barbed-end actin filament capping IEA
 biological_processGO:0051490 negative regulation of filopodium assembly IBA
 biological_processGO:0051693 actin filament capping IEA
 biological_processGO:0090036 regulation of protein kinase C signaling IEA
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005884 actin filament IBA
 cellular_componentGO:0005903 brush border IEA
 cellular_componentGO:0008290 F-actin capping protein complex IEA
 cellular_componentGO:0014704 intercalated disc IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030863 cortical cytoskeleton IEA
 cellular_componentGO:0031674 I band IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0048487 beta-tubulin binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
HSP90 chaperone cycle for steroid hormone receptors (SHR)
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000013135 GALNT1 / polypeptide N-acetylgalactosaminyltransferase 1 / O08912* / Q10472* / Polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase 1 soluble form*  / reaction / complex
 ENSGALG00000043437 P28497 / CAPZA2 / F-actin-capping protein subunit alpha-2 / P47754* / P47755* / capping actin protein of muscle Z-line alpha subunit 2*  / complex / reaction
 ENSGALG00000017320 RAB6A / Q1KME6 / Ras-related protein Rab-6A / RAB6D* / RAB6C* / Q9H0N0* / P35279* / P20340* / RAB6A, member RAS oncogene family* / RAB6D, member RAS oncogene family* / RAB6C, member RAS on...  / reaction / complex
 ENSGALG00000008086 ACTR1A / ARP1 actin related protein 1 homolog A / P61163* / P61164* / Alpha-centractin *  / complex
 ENSGALG00000011491 Q90828 / DYNC1LI1 / Cytoplasmic dynein 1 light intermediate chain 1 / Q8R1Q8* / Q9Y6G9* / dynein cytoplasmic 1 light intermediate chain 1*  / complex
 ENSGALG00000011106 GALNT2 / polypeptide N-acetylgalactosaminyltransferase 2 / Q6PB93* / Q10471* / Gm20388* / predicted gene 20388* / Polypeptide N-acetylgalactosaminyltransferase 2 Polypeptide N-acetylgalacto...  / complex / reaction
 ENSGALG00000001547 P13127 / CAPZA1 / F-actin-capping protein subunit alpha-1 / P52907* / 4933400A11Rik* / RIKEN cDNA 4933400A11 gene* / capping actin protein of muscle Z-line alpha subunit 1*  / reaction / complex
 ENSGALG00000021365 DCTN3 / dynactin subunit 3 / O75935* / Q9Z0Y1*  / complex
 ENSGALG00000005241 DYNC1LI2 / cytoplasmic dynein 1 light intermediate chain 2 / O43237* / Q6PDL0* / dynein cytoplasmic 1 light intermediate chain 2*  / complex
 ENSGALG00000005522 DYNLL2 / dynein light chain LC8-type 2 / Q96FJ2* / Q9D0M5* / Dynein light chain 2, cytoplasmic *  / complex
 ENSGALG00000020999 DYNLL1 / dynein light chain LC8-type 1 / P63168* / P63167* / BC048507* / cDNA sequence BC048507* / Dynein light chain 1, cytoplasmic *  / complex
 ENSGALG00000005834 Q9PTR5 / PAFAH1B1 / Lissencephaly-1 homolog / P43034* / P63005* / platelet-activating factor acetylhydrolase, isoform 1b, subunit 1* / platelet activating factor acetylhydrolase 1b regulat...  / complex
 ENSGALG00000011330 DYNC1H1 / dynein cytoplasmic 1 heavy chain 1 / Q14204* / Q9JHU4* / Cytoplasmic dynein 1 heavy chain 1 *  / complex
 ENSGALG00000004534 DCTN4 / dynactin subunit 4 / Q8CBY8* / Q9UJW0* / Mus musculus dynactin 4 (Dctn4), transcript variant 2, mRNA.*  / complex
 ENSGALG00000006088 DCTN5 / dynactin subunit 5 / Q9BTE1* / Q9QZB9*  / complex
 ENSGALG00000013125 CAPZA3 / capping actin protein of muscle Z-line alpha subunit 3 / P70190* / Q96KX2* / F-actin-capping protein subunit alpha-3 *  / complex
 ENSGALG00000010298 DCTN6 / dynactin subunit 6 / O00399* / Q9WUB4*  / complex






 

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