ENSGALG00000043437


Gallus gallus

Features
Gene ID: ENSGALG00000043437
  
Biological name :CAPZA2
  
Synonyms : CAPZA2 / F-actin-capping protein subunit alpha-2 / P28497
  
Possible biological names infered from orthology : capping actin protein of muscle Z-line alpha subunit 2 / P47754 / P47755
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 24865850
Gene end: 24895638
  
Corresponding Affymetrix probe sets: Gga.3338.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049210
Ensembl peptide - ENSGALP00000063472
Ensembl peptide - ENSGALP00000056878
NCBI entrez gene - 417771     See in Manteia.
RefSeq - NM_001004380
RefSeq Peptide - NP_001004380
swissprot - A0M8U0
swissprot - A0A1L1RXA4
swissprot - A0A1D5P911
swissprot - P28497
Ensembl - ENSGALG00000043437
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CAPZA2ENSG00000198898Homo sapiens
 Capza2ENSMUSG00000015733Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P13127 / CAPZA1 / F-actin-capping protein subunit alpha-1 / P52907* / 4933400A11Rik* / RIKEN cDNA 4933400A11 gene* / capping actin protein of muscle Z-line alpha subunit 1*ENSGALG0000000154780
CAPZA3 / capping actin protein of muscle Z-line alpha subunit 3 / P70190* / Q96KX2* / F-actin-capping protein subunit alpha-3 *ENSGALG0000001312535


Protein motifs (from Interpro)
Interpro ID Name
 IPR002189  F-actin-capping protein subunit alpha
 IPR017865  F-actin capping protein, alpha subunit, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0051016 barbed-end actin filament capping IEA
 biological_processGO:0051693 actin filament capping IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005903 brush border IEA
 cellular_componentGO:0008290 F-actin capping protein complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0030863 cortical cytoskeleton IEA
 molecular_functionGO:0003779 actin binding IEA


Pathways (from Reactome)
Pathway description
HSP90 chaperone cycle for steroid hormone receptors (SHR)
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Advanced glycosylation endproduct receptor signaling
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004034 CAPZB / P14315 / F-actin-capping protein subunit beta isoforms 1 and 2 / P47757* / P47756* / F-actin-capping protein subunit beta * / capping actin protein of muscle Z-line beta subunit*  / complex / reaction
 ENSGALG00000004534 DCTN4 / dynactin subunit 4 / Q8CBY8* / Q9UJW0* / Mus musculus dynactin 4 (Dctn4), transcript variant 2, mRNA.*  / complex
 ENSGALG00000006088 DCTN5 / dynactin subunit 5 / Q9BTE1* / Q9QZB9*  / complex
 ENSGALG00000010298 DCTN6 / dynactin subunit 6 / O00399* / Q9WUB4*  / complex
 ENSGALG00000021365 DCTN3 / dynactin subunit 3 / O75935* / Q9Z0Y1*  / complex
 ENSGALG00000006217 S100B / S100 calcium binding protein B / P04271* / P50114* / S100 protein, beta polypeptide, neural*  / complex / reaction
 ENSGALG00000011330 DYNC1H1 / dynein cytoplasmic 1 heavy chain 1 / Q14204* / Q9JHU4* / Cytoplasmic dynein 1 heavy chain 1 *  / complex
 ENSGALG00000020999 DYNLL1 / dynein light chain LC8-type 1 / P63168* / P63167* / BC048507* / cDNA sequence BC048507* / Dynein light chain 1, cytoplasmic *  / complex
 ENSGALG00000005834 Q9PTR5 / PAFAH1B1 / Lissencephaly-1 homolog / P43034* / P63005* / platelet-activating factor acetylhydrolase, isoform 1b, subunit 1* / platelet activating factor acetylhydrolase 1b regulat...  / complex
 ENSGALG00000005522 DYNLL2 / dynein light chain LC8-type 2 / Q96FJ2* / Q9D0M5* / Dynein light chain 2, cytoplasmic *  / complex
 ENSGALG00000005241 DYNC1LI2 / cytoplasmic dynein 1 light intermediate chain 2 / O43237* / Q6PDL0* / dynein cytoplasmic 1 light intermediate chain 2*  / complex
 ENSGALG00000011106 GALNT2 / polypeptide N-acetylgalactosaminyltransferase 2 / Q6PB93* / Q10471* / Gm20388* / predicted gene 20388* / Polypeptide N-acetylgalactosaminyltransferase 2 Polypeptide N-acetylgalacto...  / reaction / complex
 ENSGALG00000011491 Q90828 / DYNC1LI1 / Cytoplasmic dynein 1 light intermediate chain 1 / Q8R1Q8* / Q9Y6G9* / dynein cytoplasmic 1 light intermediate chain 1*  / complex
 ENSGALG00000008086 ACTR1A / ARP1 actin related protein 1 homolog A / P61163* / P61164* / Alpha-centractin *  / complex
 ENSGALG00000013135 GALNT1 / polypeptide N-acetylgalactosaminyltransferase 1 / O08912* / Q10472* / Polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase 1 soluble form*  / complex / reaction
 ENSGALG00000017320 RAB6A / Q1KME6 / Ras-related protein Rab-6A / RAB6D* / RAB6C* / Q9H0N0* / P35279* / P20340* / RAB6A, member RAS oncogene family* / RAB6D, member RAS oncogene family* / RAB6C, member RAS on...  / complex / reaction






 

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