ENSGALG00000017320


Gallus gallus

Features
Gene ID: ENSGALG00000017320
  
Biological name :RAB6A
  
Synonyms : Q1KME6 / RAB6A / Ras-related protein Rab-6A
  
Possible biological names infered from orthology : P20340 / P35279 / Q9H0N0 / RAB6A, member RAS oncogene family / RAB6C / RAB6C, member RAS oncogene family / RAB6D / RAB6D, member RAS oncogene family
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 195646633
Gene end: 195705339
  
Corresponding Affymetrix probe sets: Gga.14080.1.A1_at (Chicken Array)   Gga.14080.1.S1_at (Chicken Array)   Gga.17680.1.S1_at (Chicken Array)   Gga.186.1.S1_at (Chicken Array)   Gga.186.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000030639
Ensembl peptide - ENSGALP00000061375
Ensembl peptide - ENSGALP00000052195
NCBI entrez gene - 419063     See in Manteia.
RefSeq - NM_001044640
RefSeq - XM_015280973
RefSeq Peptide - NP_001038105
swissprot - A0A1I7Q432
swissprot - A0A1D5PHB7
swissprot - Q1KME6
Ensembl - ENSGALG00000017320
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab6aENSDARG00000103714Danio rerio
 RAB6AENSG00000175582Homo sapiens
 RAB6CENSG00000222014Homo sapiens
 RAB6DENSG00000233087Homo sapiens
 Rab6aENSMUSG00000030704Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAB6B / RAB6B, member RAS oncogene family / P61294* / Q9NRW1*ENSGALG0000002627891
RAB36 / RAB36, member RAS oncogene family / O95755* / Q8CAM5* / Mus musculus RAB36, member RAS onco family (Rab36), transcript variant 1, mRNA.*ENSGALG0000000671035
RAB34 / RAB34, member RAS oncogene family / P0DI83* / Q9BZG1*ENSGALG0000002631533


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER ISS
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0034067 protein localization to Golgi apparatus ISS
 biological_processGO:0042147 retrograde transport, endosome to Golgi IBA
 cellular_componentGO:0000139 Golgi membrane ISS
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
COPI-independent Golgi-to-ER retrograde traffic
Retrograde transport at the Trans-Golgi-Network
TBC/RABGAPs
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001547 P13127 / CAPZA1 / F-actin-capping protein subunit alpha-1 / P52907* / 4933400A11Rik* / RIKEN cDNA 4933400A11 gene* / capping actin protein of muscle Z-line alpha subunit 1*  / reaction / complex
 ENSGALG00000002394 RGP1 / RGP1 homolog, RAB6A GEF complex partner 1 / Q8BHT7* / Q92546* / RAB6A-GEF complex partner protein 2 *  / reaction / complex
 ENSGALG00000004034 CAPZB / P14315 / F-actin-capping protein subunit beta isoforms 1 and 2 / P47757* / P47756* / F-actin-capping protein subunit beta * / capping actin protein of muscle Z-line beta subunit*  / reaction / complex
 ENSGALG00000004534 DCTN4 / dynactin subunit 4 / Q8CBY8* / Q9UJW0* / Mus musculus dynactin 4 (Dctn4), transcript variant 2, mRNA.*  / complex / reaction
 ENSGALG00000008086 ACTR1A / ARP1 actin related protein 1 homolog A / P61163* / P61164* / Alpha-centractin *  / reaction / complex
 ENSGALG00000020999 DYNLL1 / dynein light chain LC8-type 1 / P63168* / P63167* / BC048507* / cDNA sequence BC048507* / Dynein light chain 1, cytoplasmic *  / reaction / complex
 ENSGALG00000005522 DYNLL2 / dynein light chain LC8-type 2 / Q96FJ2* / Q9D0M5* / Dynein light chain 2, cytoplasmic *  / reaction / complex
 ENSGALG00000006088 DCTN5 / dynactin subunit 5 / Q9BTE1* / Q9QZB9*  / complex / reaction
 ENSGALG00000005241 DYNC1LI2 / cytoplasmic dynein 1 light intermediate chain 2 / O43237* / Q6PDL0* / dynein cytoplasmic 1 light intermediate chain 2*  / complex / reaction
 ENSGALG00000005834 Q9PTR5 / PAFAH1B1 / Lissencephaly-1 homolog / P43034* / P63005* / platelet-activating factor acetylhydrolase, isoform 1b, subunit 1* / platelet activating factor acetylhydrolase 1b regulat...  / reaction
 ENSGALG00000015036 RIC1 / RIC1 homolog, RAB6A GEF complex partner 1 / Q4ADV7* / Q69ZJ7* / RAB6A-GEF complex partner protein 1 *  / reaction / complex
 ENSGALG00000011491 Q90828 / DYNC1LI1 / Cytoplasmic dynein 1 light intermediate chain 1 / Q8R1Q8* / Q9Y6G9* / dynein cytoplasmic 1 light intermediate chain 1*  / complex / reaction
 ENSGALG00000001225 RABGAP1 / RAB GTPase activating protein 1 / A2AWA9* / Q9Y3P9*  / complex / reaction
 ENSGALG00000013125 CAPZA3 / capping actin protein of muscle Z-line alpha subunit 3 / P70190* / Q96KX2* / F-actin-capping protein subunit alpha-3 *  / reaction / complex
 ENSGALG00000013135 GALNT1 / polypeptide N-acetylgalactosaminyltransferase 1 / O08912* / Q10472* / Polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase 1 soluble form*  / complex / reaction
 ENSGALG00000011106 GALNT2 / polypeptide N-acetylgalactosaminyltransferase 2 / Q6PB93* / Q10471* / Gm20388* / predicted gene 20388* / Polypeptide N-acetylgalactosaminyltransferase 2 Polypeptide N-acetylgalacto...  / complex / reaction
 ENSGALG00000021365 DCTN3 / dynactin subunit 3 / O75935* / Q9Z0Y1*  / complex / reaction
 ENSGALG00000010298 DCTN6 / dynactin subunit 6 / O00399* / Q9WUB4*  / reaction / complex
 ENSGALG00000043437 P28497 / CAPZA2 / F-actin-capping protein subunit alpha-2 / P47754* / P47755* / capping actin protein of muscle Z-line alpha subunit 2*  / reaction / complex
 ENSGALG00000011330 DYNC1H1 / dynein cytoplasmic 1 heavy chain 1 / Q14204* / Q9JHU4* / Cytoplasmic dynein 1 heavy chain 1 *  / reaction / complex






 

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