ENSDARG00000103714


Danio rerio

Features
Gene ID: ENSDARG00000103714
  
Biological name :rab6a
  
Synonyms : rab6a / RAB6A, member RAS oncogene family
  
Possible biological names infered from orthology : P20340 / P35279 / Q9H0N0 / RAB6C / RAB6C, member RAS oncogene family / RAB6D / RAB6D, member RAS oncogene family
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 36695597
Gene end: 36711701
  
Corresponding Affymetrix probe sets: Dr.1519.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000130990
Ensembl peptide - ENSDARP00000134740
NCBI entrez gene - 793785     See in Manteia.
RefSeq - NM_001328529
RefSeq - NM_001328530
RefSeq Peptide - NP_001315458
RefSeq Peptide - NP_001315459
swissprot - A0A0R4IH39
swissprot - A9ULS4
ZFIN ID - ZDB-GENE-040426-2849
Ensembl - ENSDARG00000103714
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAB6AENSGALG00000017320Gallus gallus
 RAB6AENSG00000175582Homo sapiens
 RAB6CENSG00000222014Homo sapiens
 RAB6DENSG00000233087Homo sapiens
 Rab6aENSMUSG00000030704Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rab6ba / RAB6B, member RAS oncogene family a / RAB6B* / Q9NRW1* / P61294* / RAB6B, member RAS oncogene family*ENSDARG0000003452290
rab41 / RAB41, member RAS oncogene familyENSDARG0000002988588
rab6bb / RAB6B, member RAS oncogene family b / RAB6B* / Q9NRW1* / P61294* / RAB6B, member RAS oncogene family*ENSDARG0000003134387
rab34b / RAB34, member RAS oncogene family b / RAB34* / Q9BZG1* / P0DI83* / RAB34, member RAS oncogene family*ENSDARG0000001097734
rab34a / RAB34, member RAS oncogene family a / RAB34* / Q9BZG1* / P0DI83* / RAB34, member RAS oncogene family*ENSDARG0000004562834
rab36 / RAB36, member RAS oncogene family / O95755* / Q8CAM5* / Mus musculus RAB36, member RAS onco family (Rab36), transcript variant 1, mRNA.*ENSDARG0000001405832


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IBA
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport IBA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IBA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
COPI-independent Golgi-to-ER retrograde traffic
Retrograde transport at the Trans-Golgi-Network
TBC/RABGAPs
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000006545 rgp1 / GP1 homolog, RAB6A GEF complex partner 1 / Q92546* / Q8BHT7* / RAB6A-GEF complex partner protein 2 * / RGP1 homolog, RAB6A GEF complex partner 1*  / reaction / complex
 ENSDARG00000061335 galnt1 / UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 / Q10472* / O08912* / polypeptide N-acetylgalactosaminyltransferase 1* / Polypeptide N-acetylgala...  / reaction / complex
 ENSDARG00000079496 bicd1a / bicaudal D homolog 1a / BICD1* / Q8BR07* / Q96G01* / BICD cargo adaptor 1* / Protein bicaudal D homolog 1 *  / reaction / complex
 ENSDARG00000003829 galnt2 / UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 / Q10471* / Q6PB93* / Gm20388* / predicted gene 20388* / polypeptide N-acetylgalactosaminyltransf...  / complex / reaction
 ENSDARG00000056122 gdi1 / GDP dissociation inhibitor 1 / P31150* / P50396* / Rab GDP dissociation inhibitor alpha *  / complex
 ENSDARG00000098967 rabgap1 / RAB GTPase activating protein 1 / Q9Y3P9*  / reaction / complex






 

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