ENSDARG00000006545


Danio rerio

Features
Gene ID: ENSDARG00000006545
  
Biological name :rgp1
  
Synonyms : GP1 homolog, RAB6A GEF complex partner 1 / rgp1
  
Possible biological names infered from orthology : Q8BHT7 / Q92546 / RAB6A-GEF complex partner protein 2 / RGP1 homolog, RAB6A GEF complex partner 1
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 24627076
Gene end: 24645540
  
Corresponding Affymetrix probe sets: Dr.17500.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000117589
Ensembl peptide - ENSDARP00000048920
Ensembl peptide - ENSDARP00000147197
NCBI entrez gene - 436881     See in Manteia.
swissprot - E9QES3
swissprot - Q6DHI8
ZFIN ID - ZDB-GENE-040718-352
Ensembl - ENSDARG00000006545
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RGP1ENSGALG00000002394Gallus gallus
 RGP1ENSG00000107185Homo sapiens
 Rgp1ENSMUSG00000028468Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR014848  Reduced growth phenotype protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042147 retrograde transport, endosome to Golgi IBA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0000139 Golgi membrane IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0034066 RIC1-RGP1 guanyl-nucleotide exchange factor complex IBA
 molecular_functionGO:0017112 Rab guanyl-nucleotide exchange factor activity IBA
 molecular_functionGO:0017137 Rab GTPase binding IBA


Pathways (from Reactome)
Pathway description
Intra-Golgi traffic
Retrograde transport at the Trans-Golgi-Network
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000056122 gdi1 / GDP dissociation inhibitor 1 / P31150* / P50396* / Rab GDP dissociation inhibitor alpha *  / reaction
 ENSDARG00000052290 rab33ba / RAB33B, member RAS oncogene family a / RAB33B* / O35963* / Q9H082* / RAB33B, member RAS oncogene family*  / complex / reaction
 ENSDARG00000103714 rab6a / RAB6A, member RAS oncogene family / RAB6C* / RAB6D* / P20340* / Q9H0N0* / P35279* / RAB6C, member RAS oncogene family* / RAB6D, member RAS oncogene family*  / reaction / complex






 

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contact: otassy@igbmc.fr