ENSGALG00000008086


Gallus gallus

Features
Gene ID: ENSGALG00000008086
  
Biological name :ACTR1A
  
Synonyms : ACTR1A / ARP1 actin related protein 1 homolog A
  
Possible biological names infered from orthology : Alpha-centractin / P61163 / P61164
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 23169231
Gene end: 23183400
  
Corresponding Affymetrix probe sets: Gga.7462.1.S1_at (Chicken Array)   GgaAffx.11629.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046194
Ensembl peptide - ENSGALP00000063156
Ensembl peptide - ENSGALP00000013109
NCBI entrez gene - 423862     See in Manteia.
RefSeq - NM_001007948
RefSeq Peptide - NP_001007949
swissprot - A0A1D5P0L6
swissprot - Q5ZM58
Ensembl - ENSGALG00000008086
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ACTR1AENSG00000138107Homo sapiens
 Actr1aENSMUSG00000025228Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACTA2 / actin, aortic smooth muscle / P62737* / P62736* / actin, alpha 2, smooth muscle, aorta* / Actin, aortic smooth muscle Actin, aortic smooth muscle, intermediate form*ENSGALG0000000634347
ACTB / P60706 / Actin, cytoplasmic 1 Actin, cytoplasmic 1, N-terminally processed / P60709* / P60710* / actin beta*ENSGALG0000000962147
ACTC1 / P68034 / Actin, alpha cardiac muscle 1 / P68032* / P68033*ENSGALG0000000984446
ENSGALG0000004041546
ACTG2 / P63270 / Actin, gamma-enteric smooth muscle / P63267* / P63268* / actin, gamma 2, smooth muscle, enteric*ENSGALG0000004163446
ACTG1 / P53478 / Actin, cytoplasmic type 5 / Actb* / POTEJ* / P0CG39* / P60710* / POTE ankyrin domain family member J* / Actin, cytoplasmic 1 Actin, cytoplasmic 1, N-terminally processed*ENSGALG0000000138146
ACTC2L / Q5ZMQ2 / Actin, cytoplasmic 2 Actin, cytoplasmic 2, N-terminally processedENSGALG0000002874944
ACTRT1* / ACTRT2* / Q9D9L5* / Q8TDY3* / Q9D9J3* / Q8TDG2* / actin related protein T2* / actin related protein T1*ENSGALG0000000107843
ACTA1 / actin, alpha skeletal muscle ENSGALG0000001108643
ACTL9 / actin like 9 / Q8CG27* / Q8TC94* / Actin-like protein 9 *ENSGALG0000000144026


Protein motifs (from Interpro)
Interpro ID Name
 IPR004000  Actin family
 IPR004001  Actin, conserved site
 IPR020902  Actin/actin-like conserved site
 IPR029909  Actin-related protein 1 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005869 dynactin complex IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0099738 cell cortex region IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001547 P13127 / CAPZA1 / F-actin-capping protein subunit alpha-1 / P52907* / 4933400A11Rik* / RIKEN cDNA 4933400A11 gene* / capping actin protein of muscle Z-line alpha subunit 1*  / complex
 ENSGALG00000004034 CAPZB / P14315 / F-actin-capping protein subunit beta isoforms 1 and 2 / P47757* / P47756* / F-actin-capping protein subunit beta * / capping actin protein of muscle Z-line beta subunit*  / complex
 ENSGALG00000004534 DCTN4 / dynactin subunit 4 / Q8CBY8* / Q9UJW0* / Mus musculus dynactin 4 (Dctn4), transcript variant 2, mRNA.*  / complex
 ENSGALG00000005241 DYNC1LI2 / cytoplasmic dynein 1 light intermediate chain 2 / O43237* / Q6PDL0* / dynein cytoplasmic 1 light intermediate chain 2*  / complex
 ENSGALG00000011106 GALNT2 / polypeptide N-acetylgalactosaminyltransferase 2 / Q6PB93* / Q10471* / Gm20388* / predicted gene 20388* / Polypeptide N-acetylgalactosaminyltransferase 2 Polypeptide N-acetylgalacto...  / reaction / complex
 ENSGALG00000011330 DYNC1H1 / dynein cytoplasmic 1 heavy chain 1 / Q14204* / Q9JHU4* / Cytoplasmic dynein 1 heavy chain 1 *  / complex
 ENSGALG00000005834 Q9PTR5 / PAFAH1B1 / Lissencephaly-1 homolog / P43034* / P63005* / platelet-activating factor acetylhydrolase, isoform 1b, subunit 1* / platelet activating factor acetylhydrolase 1b regulat...  / complex
 ENSGALG00000005522 DYNLL2 / dynein light chain LC8-type 2 / Q96FJ2* / Q9D0M5* / Dynein light chain 2, cytoplasmic *  / complex
 ENSGALG00000017320 RAB6A / Q1KME6 / Ras-related protein Rab-6A / RAB6D* / RAB6C* / Q9H0N0* / P35279* / P20340* / RAB6A, member RAS oncogene family* / RAB6D, member RAS oncogene family* / RAB6C, member RAS on...  / reaction / complex
 ENSGALG00000013135 GALNT1 / polypeptide N-acetylgalactosaminyltransferase 1 / O08912* / Q10472* / Polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase 1 soluble form*  / reaction / complex
 ENSGALG00000021365 DCTN3 / dynactin subunit 3 / O75935* / Q9Z0Y1*  / complex
 ENSGALG00000020999 DYNLL1 / dynein light chain LC8-type 1 / P63168* / P63167* / BC048507* / cDNA sequence BC048507* / Dynein light chain 1, cytoplasmic *  / complex
 ENSGALG00000011491 Q90828 / DYNC1LI1 / Cytoplasmic dynein 1 light intermediate chain 1 / Q8R1Q8* / Q9Y6G9* / dynein cytoplasmic 1 light intermediate chain 1*  / complex
 ENSGALG00000008086 ACTR1A / ARP1 actin related protein 1 homolog A / P61163* / P61164* / Alpha-centractin *  / complex
 ENSGALG00000006088 DCTN5 / dynactin subunit 5 / Q9BTE1* / Q9QZB9*  / complex
 ENSGALG00000013125 CAPZA3 / capping actin protein of muscle Z-line alpha subunit 3 / P70190* / Q96KX2* / F-actin-capping protein subunit alpha-3 *  / complex
 ENSGALG00000010298 DCTN6 / dynactin subunit 6 / O00399* / Q9WUB4*  / complex
 ENSGALG00000043437 P28497 / CAPZA2 / F-actin-capping protein subunit alpha-2 / P47754* / P47755* / capping actin protein of muscle Z-line alpha subunit 2*  / complex






 

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