ENSGALG00000009621


Gallus gallus

Features
Gene ID: ENSGALG00000009621
  
Biological name :ACTB
  
Synonyms : ACTB / Actin, cytoplasmic 1 Actin, cytoplasmic 1, N-terminally processed / P60706
  
Possible biological names infered from orthology : actin beta / P60709 / P60710
  
Species: Gallus gallus
  
Chr. number: 14
Strand: -1
Band:
Gene start: 4191291
Gene end: 4195531
  
Corresponding Affymetrix probe sets: AFFX-Gga-actin-3_at (Chicken Array)   AFFX-Gga-actin-5_a_at (Chicken Array)   AFFX-Gga-actin-M_at (Chicken Array)   Gga.8939.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048205
Ensembl peptide - ENSGALP00000062561
Ensembl peptide - ENSGALP00000062248
Ensembl peptide - ENSGALP00000061593
Ensembl peptide - ENSGALP00000061553
Ensembl peptide - ENSGALP00000061443
Ensembl peptide - ENSGALP00000061412
Ensembl peptide - ENSGALP00000060844
Ensembl peptide - ENSGALP00000060181
Ensembl peptide - ENSGALP00000059632
Ensembl peptide - ENSGALP00000015657
NCBI entrez gene - 396526     See in Manteia.
RefSeq - NM_205518
RefSeq Peptide - NP_990849
swissprot - A0A1L1RRX5
swissprot - A0A1L1RRL2
swissprot - A0A1L1RRH8
swissprot - A0A1L1RPY3
swissprot - A0A1L1RN10
swissprot - A0A1L1RLK7
swissprot - A0A1D5P681
swissprot - A0A1L1RUQ9
swissprot - P60706
swissprot - A0A1L1RTU4
Ensembl - ENSGALG00000009621
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 actb1ENSDARG00000037746Danio rerio
 actb2ENSDARG00000037870Danio rerio
 ACTBENSG00000075624Homo sapiens
 ActbENSMUSG00000029580Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACTG1 / P53478 / Actin, cytoplasmic type 5 / Actb* / POTEJ* / P0CG39* / P60710* / POTE ankyrin domain family member J* / Actin, cytoplasmic 1 Actin, cytoplasmic 1, N-terminally processed*ENSGALG0000000138199
ACTC1 / P68034 / Actin, alpha cardiac muscle 1 / P68032* / P68033*ENSGALG0000000984494
ACTA2 / actin, aortic smooth muscle / P62737* / P62736* / actin, alpha 2, smooth muscle, aorta* / Actin, aortic smooth muscle Actin, aortic smooth muscle, intermediate form*ENSGALG0000000634394
ACTG2 / P63270 / Actin, gamma-enteric smooth muscle / P63267* / P63268* / actin, gamma 2, smooth muscle, enteric*ENSGALG0000004163493
ENSGALG0000004041593
ACTA1 / actin, alpha skeletal muscle ENSGALG0000001108688
ACTC2L / Q5ZMQ2 / Actin, cytoplasmic 2 Actin, cytoplasmic 2, N-terminally processedENSGALG0000002874987
ACTRT1* / ACTRT2* / Q9D9L5* / Q8TDY3* / Q9D9J3* / Q8TDG2* / actin related protein T2* / actin related protein T1*ENSGALG0000000107861
ACTR1A / ARP1 actin related protein 1 homolog A / P61163* / P61164* / Alpha-centractin *ENSGALG0000000808649
ACTL9 / actin like 9 / Q8CG27* / Q8TC94* / Actin-like protein 9 *ENSGALG0000000144034


Protein motifs (from Interpro)
Interpro ID Name
 IPR004000  Actin family
 IPR004001  Actin, conserved site
 IPR020902  Actin/actin-like conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0048870 cell motility IEA
 biological_processGO:0072749 cellular response to cytochalasin B IEA
 biological_processGO:0098974 postsynaptic actin cytoskeleton organization IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IDA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0005925 focal adhesion IDA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0030027 lamellipodium IDA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0035267 NuA4 histone acetyltransferase complex IEA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IEA
 cellular_componentGO:0097433 dense body IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019894 kinesin binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030957 Tat protein binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0050998 nitric-oxide synthase binding IEA
 molecular_functionGO:0098973 structural constituent of postsynaptic actin cytoskeleton IEA


Pathways (from Reactome)
Pathway description
Gap junction degradation
Formation of annular gap junctions
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
EPH-ephrin mediated repulsion of cells
VEGFA-VEGFR2 Pathway
B-WICH complex positively regulates rRNA expression
RHO GTPases activate IQGAPs
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate Formins
MAP2K and MAPK activation
UCH proteinases
DNA Damage Recognition in GG-NER
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007130 RAC1 / Rac family small GTPase 1 / P63000* / P63001* / RAS-related C3 botulinum substrate 1*  / complex / reaction
 ENSGALG00000004796 CDC42 / Q90694 / Cell division control protein 42 homolog / P60766* / P60953* / cell division cycle 42* / Cell division control *  / complex / reaction
 ENSGALG00000006609 EPHB1 / EPH receptor B1 / P54762* / Q8CBF3* / Ephrin type-B receptor 1 *  / reaction / complex
 ENSGALG00000000816 SRGAP2* / O75044* / P0DJJ0* / P0DMP2* / Q91Z67* / SRGAP2C* / SRGAP2B* / SLIT-ROBO Rho GTPase activating protein 2* / SLIT-ROBO Rho GTPase activating protein 2B* / SLIT-ROBO Rho GTPase activ...  / reaction / complex
 ENSGALG00000029175 EFNB2 / ephrin B2 / P52799* / P52800*  / reaction / complex
 ENSGALG00000009621 ACTB / P60706 / Actin, cytoplasmic 1 Actin, cytoplasmic 1, N-terminally processed / P60709* / P60710* / actin beta*  / reaction / - / complex
 ENSGALG00000030162 IQGAP1 / IQ motif containing GTPase activating protein 1 / P46940* / Q9JKF1* / Ras GTPase-activating-like protein IQGAP1 *  / reaction / complex
 ENSGALG00000042538 BAIAP2 / BAI1 associated protein 2 / Q8BKX1* / Q9UQB8* / Brain-specific angiosis inhibitor 1-associated protein 2 *  / reaction / complex
 ENSGALG00000014978 IQGAP2 / IQ motif containing GTPase activating protein 2 / Q13576* / Q3UQ44* / Ras GTPase-activating-like protein IQGAP2 *  / reaction / complex
 ENSGALG00000002709 MYO1C / unconventional myosin-Ic / O00159* / Q9WTI7* / myosin IC*  / complex
 ENSGALG00000004741 EPHB2 / EPH receptor B2 / P29323* / P54763* / Ephrin type-B receptor 2 *  / reaction / complex






 

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