ENSGALG00000000816


Gallus gallus

Features
Gene ID: ENSGALG00000000816
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : O75044 / P0DJJ0 / P0DMP2 / Q91Z67 / SLIT-ROBO Rho GTPase activating protein 2 / SLIT-ROBO Rho GTPase activating protein 2B / SLIT-ROBO Rho GTPase activating protein 2C / SRGAP2 / SRGAP2B / SRGAP2C
  
Species: Gallus gallus
  
Chr. number: 26
Strand: 1
Band:
Gene start: 2389798
Gene end: 2464057
  
Corresponding Affymetrix probe sets: Gga.13636.1.S1_at (Chicken Array)   GgaAffx.22214.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001187
NCBI entrez gene - 419843     See in Manteia.
RefSeq - XM_004934954
RefSeq - XM_015299065
RefSeq - XM_004934955
RefSeq - XM_015299064
swissprot - E1BZR0
Ensembl - ENSGALG00000000816
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B0S6J3ENSDARG00000032161Danio rerio
 O75044ENSG00000266028Homo sapiens
 P0DJJ0ENSG00000171943Homo sapiens
 P0DMP2ENSG00000196369Homo sapiens
 Q91Z67ENSMUSG00000026425Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SRGAP1 / SLIT-ROBO Rho GTPase activating protein 1 / Q7Z6B7* / Q91Z69*ENSGALG0000000982572
SRGAP3 / SLIT-ROBO Rho GTPase activating protein 3 / O43295*ENSGALG0000000837865
ARHGAP25 / rho GTPase-activating protein 25 / P42331* / Q8BYW1*ENSGALG0000003519412
ARHGAP17 / Rho GTPase activating protein 17 / Q3UIA2* / Q68EM7*ENSGALG0000004121312
Q17R89* / Q5SSM3* / ARHGAP44* / Rho GTPase activating protein 44*ENSGALG0000000131110
P55194* / Q9Y3L3* / SH3BP1* / Z83844.3* / AL592169.1* / SH3 domain binding protein 1*ENSGALG0000001242210
ARHGAP24 / Rho GTPase activating protein 24 / Q8C4V1* / Q8N264*ENSGALG000000111249
Q7Z5H3* / Q8BL80* / ARHGAP22* / Rho GTPase activating protein 22*ENSGALG000000061378


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001060  FCH domain
 IPR001452  SH3 domain
 IPR008936  Rho GTPase activation protein
 IPR030252  SLIT-ROBO Rho GTPase-activating protein 2
 IPR031160  F-BAR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0021816 extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration IEA
 biological_processGO:0030336 negative regulation of cell migration IBA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046847 filopodium assembly IEA
 biological_processGO:0048812 neuron projection morphogenesis IEA
 biological_processGO:0060996 dendritic spine development IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0045335 phagocytic vesicle IEA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0048365 Rac GTPase binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007130 RAC1 / Rac family small GTPase 1 / P63000* / P63001* / RAS-related C3 botulinum substrate 1*  / complex / reaction
 ENSGALG00000009621 ACTB / P60706 / Actin, cytoplasmic 1 Actin, cytoplasmic 1, N-terminally processed / P60709* / P60710* / actin beta*  / reaction / complex






 

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