ENSG00000196369


Homo sapiens

Features
Gene ID: ENSG00000196369
  
Biological name :SRGAP2B
  
Synonyms : P0DMP2 / SLIT-ROBO Rho GTPase activating protein 2B / SRGAP2B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q21.1
Gene start: 144887265
Gene end: 145095528
  
Corresponding Affymetrix probe sets: 1568955_at (Human Genome U133 Plus 2.0 Array)   1568957_x_at (Human Genome U133 Plus 2.0 Array)   228628_at (Human Genome U133 Plus 2.0 Array)   232095_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000479960
Ensembl peptide - ENSP00000493121
Ensembl peptide - ENSP00000484189
Ensembl peptide - ENSP00000477776
NCBI entrez gene - 647135     See in Manteia.
OMIM - 614703
RefSeq - XM_017002092
RefSeq - XM_017002085
RefSeq - XM_017002086
RefSeq - XM_017002088
RefSeq - XM_017002089
RefSeq - XM_017002090
RefSeq - XM_017002091
RefSeq - NM_001271870
RefSeq - XM_005277421
RefSeq - XM_005277422
RefSeq Peptide - NP_001258799
RefSeq Peptide - NP_001317613
swissprot - A0A286YEY3
swissprot - A0A087X1G6
swissprot - A0A087WW56
swissprot - P0DMP2
Ensembl - ENSG00000196369
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B0S6J3ENSDARG00000032161Danio rerio
 ENSGALG00000000816Gallus gallus
 Q91Z67ENSMUSG00000026425Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P0DJJ0 / SRGAP2C / SLIT-ROBO Rho GTPase activating protein 2CENSG0000017194399
O75044 / SRGAP2 / SLIT-ROBO Rho GTPase activating protein 2ENSG0000026602898
Q7Z6B7 / SRGAP1 / SLIT-ROBO Rho GTPase activating protein 1ENSG0000019693578
O43295 / SRGAP3 / SLIT-ROBO Rho GTPase activating protein 3ENSG0000019622070
P98171 / ARHGAP4 / Rho GTPase activating protein 4ENSG0000008982045
Q8N264 / ARHGAP24 / Rho GTPase activating protein 24ENSG000001386399
Q17R89 / ARHGAP44 / Rho GTPase activating protein 44ENSG000000067409
Q7Z5H3 / ARHGAP22 / Rho GTPase activating protein 22ENSG000001288058
P42331 / ARHGAP25 / Rho GTPase activating protein 25ENSG000001632197
Z83844.3ENSG000002853047
Q68EM7 / ARHGAP17 / Rho GTPase activating protein 17ENSG000001407507
Q9Y3L3 / SH3BP1 / SH3 domain binding protein 1ENSG000001000927


Protein motifs (from Interpro)
Interpro ID Name
 IPR001060  FCH domain
 IPR027267  AH/BAR domain superfamily
 IPR030252  SLIT-ROBO Rho GTPase-activating protein 2
 IPR031160  F-BAR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0030336 negative regulation of cell migration IBA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0048365 Rac GTPase binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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