ENSG00000163219


Homo sapiens

Features
Gene ID: ENSG00000163219
  
Biological name :ARHGAP25
  
Synonyms : ARHGAP25 / P42331 / Rho GTPase activating protein 25
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p13.3
Gene start: 68679601
Gene end: 68826833
  
Corresponding Affymetrix probe sets: 1555076_at (Human Genome U133 Plus 2.0 Array)   204882_at (Human Genome U133 Plus 2.0 Array)   38149_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417818
Ensembl peptide - ENSP00000417467
Ensembl peptide - ENSP00000420427
Ensembl peptide - ENSP00000420583
Ensembl peptide - ENSP00000386241
Ensembl peptide - ENSP00000386863
Ensembl peptide - ENSP00000386911
Ensembl peptide - ENSP00000417139
Ensembl peptide - ENSP00000417283
Ensembl peptide - ENSP00000417425
NCBI entrez gene - 9938     See in Manteia.
OMIM - 610587
RefSeq - XM_017005428
RefSeq - XM_005264676
RefSeq - XM_011533206
RefSeq - XM_011533207
RefSeq - XM_011533208
RefSeq - XM_011533209
RefSeq - XM_011533210
RefSeq - XM_017005423
RefSeq - XM_017005424
RefSeq - XM_017005425
RefSeq - XM_017005426
RefSeq - XM_017005427
RefSeq - NM_001007231
RefSeq - NM_001166276
RefSeq - NM_001166277
RefSeq - NM_014882
RefSeq - XM_005264675
RefSeq Peptide - NP_055697
RefSeq Peptide - NP_001007232
RefSeq Peptide - NP_001159748
RefSeq Peptide - NP_001159749
swissprot - C9JB56
swissprot - V9HWC8
swissprot - B7Z8K7
swissprot - P42331
swissprot - F8WAV9
swissprot - F8WDF6
swissprot - H7C4P1
Ensembl - ENSG00000163219
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap25ENSDARG00000061784Danio rerio
 ARHGAP25ENSGALG00000035194Gallus gallus
 Q8BYW1ENSMUSG00000030047Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q7Z5H3 / ARHGAP22 / Rho GTPase activating protein 22ENSG0000012880542
Q8N264 / ARHGAP24 / Rho GTPase activating protein 24ENSG0000013863940
Q7Z6B7 / SRGAP1 / SLIT-ROBO Rho GTPase activating protein 1ENSG0000019693520
Q17R89 / ARHGAP44 / Rho GTPase activating protein 44ENSG0000000674019
O43295 / SRGAP3 / SLIT-ROBO Rho GTPase activating protein 3ENSG0000019622019
O75044 / SRGAP2 / SLIT-ROBO Rho GTPase activating protein 2ENSG0000026602818
Q68EM7 / ARHGAP17 / Rho GTPase activating protein 17ENSG0000014075018
P98171 / ARHGAP4 / Rho GTPase activating protein 4ENSG0000008982017
Q9Y3L3 / SH3BP1 / SH3 domain binding protein 1ENSG0000010009216
Z83844.3ENSG0000028530414
P0DJJ0 / SRGAP2C / SLIT-ROBO Rho GTPase activating protein 2CENSG000001719434
P0DMP2 / SRGAP2B / SLIT-ROBO Rho GTPase activating protein 2BENSG000001963693


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006911 phagocytosis, engulfment IMP
 biological_processGO:0007015 actin filament organization IMP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 biological_processGO:0051058 negative regulation of small GTPase mediated signal transduction IMP
 cellular_componentGO:0001891 phagocytic cup IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005096 GTPase activator activity TAS


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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