ENSG00000138639


Homo sapiens

Features
Gene ID: ENSG00000138639
  
Biological name :ARHGAP24
  
Synonyms : ARHGAP24 / Q8N264 / Rho GTPase activating protein 24
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q21.23
Gene start: 85475114
Gene end: 86002670
  
Corresponding Affymetrix probe sets: 221030_s_at (Human Genome U133 Plus 2.0 Array)   223422_s_at (Human Genome U133 Plus 2.0 Array)   230802_at (Human Genome U133 Plus 2.0 Array)   230803_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378611
Ensembl peptide - ENSP00000423206
Ensembl peptide - ENSP00000426105
Ensembl peptide - ENSP00000425589
Ensembl peptide - ENSP00000424256
Ensembl peptide - ENSP00000264343
Ensembl peptide - ENSP00000378610
NCBI entrez gene - 83478     See in Manteia.
OMIM - 610586
RefSeq - NM_031305
RefSeq - XM_017008679
RefSeq - XM_011532300
RefSeq - NM_001025616
RefSeq - NM_001042669
RefSeq - NM_001287805
RefSeq Peptide - NP_001020787
RefSeq Peptide - NP_001036134
RefSeq Peptide - NP_001274734
RefSeq Peptide - NP_112595
swissprot - D6RCP5
swissprot - D6RHH1
swissprot - Q8N264
swissprot - D6RBC2
Ensembl - ENSG00000138639
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap24ENSDARG00000100973Danio rerio
 ARHGAP24ENSGALG00000011124Gallus gallus
 Q8C4V1ENSMUSG00000057315Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q7Z5H3 / ARHGAP22 / Rho GTPase activating protein 22ENSG0000012880544
P42331 / ARHGAP25 / Rho GTPase activating protein 25ENSG0000016321934
O43295 / SRGAP3 / SLIT-ROBO Rho GTPase activating protein 3ENSG0000019622018
Q7Z6B7 / SRGAP1 / SLIT-ROBO Rho GTPase activating protein 1ENSG0000019693517
O75044 / SRGAP2 / SLIT-ROBO Rho GTPase activating protein 2ENSG0000026602817
Q17R89 / ARHGAP44 / Rho GTPase activating protein 44ENSG0000000674016
Q68EM7 / ARHGAP17 / Rho GTPase activating protein 17ENSG0000014075016
P98171 / ARHGAP4 / Rho GTPase activating protein 4ENSG0000008982015
Q9Y3L3 / SH3BP1 / SH3 domain binding protein 1ENSG0000010009215
Z83844.3ENSG0000028530413
P0DMP2 / SRGAP2B / SLIT-ROBO Rho GTPase activating protein 2BENSG000001963694
P0DJJ0 / SRGAP2C / SLIT-ROBO Rho GTPase activating protein 2CENSG000001719434


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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