ENSMUSG00000057315


Mus musculus

Features
Gene ID: ENSMUSG00000057315
  
Biological name :Arhgap24
  
Synonyms : Arhgap24 / Q8C4V1 / Rho GTPase activating protein 24
  
Possible biological names infered from orthology : Q8N264
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: E5
Gene start: 102481391
Gene end: 102897937
  
Corresponding Affymetrix probe sets: 10523579 (MoGene1.0st)   1424842_a_at (Mouse Genome 430 2.0 Array)   1430712_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000108475
Ensembl peptide - ENSMUSP00000108473
Ensembl peptide - ENSMUSP00000108474
Ensembl peptide - ENSMUSP00000070048
Ensembl peptide - ENSMUSP00000073028
Ensembl peptide - ENSMUSP00000092138
NCBI entrez gene - 231532     See in Manteia.
MGI - MGI:1922647
RefSeq - XM_011249434
RefSeq - NM_029270
RefSeq - NM_146161
RefSeq - XM_006534887
RefSeq - XM_006534888
RefSeq - XM_006534890
RefSeq - XM_006534891
RefSeq - XM_006534892
RefSeq - NM_001286468
RefSeq - NM_001346585
RefSeq Peptide - NP_666273
RefSeq Peptide - NP_001273397
RefSeq Peptide - NP_001333514
RefSeq Peptide - NP_083546
swissprot - Q8C4V1
swissprot - G3X9N1
swissprot - D3Z5T4
Ensembl - ENSMUSG00000057315
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap24ENSDARG00000100973Danio rerio
 ARHGAP24ENSGALG00000011124Gallus gallus
 Q8N264ENSG00000138639Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BL80 / Arhgap22 / Rho GTPase activating protein 22 / Q7Z5H3*ENSMUSG0000006350643
Q8BYW1 / Arhgap25 / Rho GTPase-activating protein 25 / P42331*ENSMUSG0000003004734
Srgap3 / SLIT-ROBO Rho GTPase activating protein 3 / O43295*ENSMUSG0000003025718
Q91Z69 / Srgap1 / SLIT-ROBO Rho GTPase-activating protein 1 / Q7Z6B7*ENSMUSG0000002012117
Q91Z67 / Srgap2 / SLIT-ROBO Rho GTPase-activating protein 2 / P0DJJ0* / P0DMP2* / O75044* / SRGAP2B* / SRGAP2C* / SLIT-ROBO Rho GTPase activating protein 2C* / SLIT-ROBO Rho GTPase activat...ENSMUSG0000002642517
Q5SSM3 / Arhgap44 / Rho GTPase-activating protein 44 / Q17R89*ENSMUSG0000003338916
Q3UIA2 / Arhgap17 / Rho GTPase-activating protein 17 / Q68EM7*ENSMUSG0000003076616
Arhgap4 / Rho GTPase activating protein 4 / P98171*ENSMUSG0000003138915
P55194 / Sh3bp1 / SH3-domain binding protein 1 / Q9Y3L3* / Z83844.3*ENSMUSG0000002243614
AL592169.1 / Q9Y3L3* / SH3BP1* / Z83844.3* / SH3 domain binding protein 1*ENSMUSG0000011606912


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035021 negative regulation of Rac protein signal transduction IMP
 biological_processGO:0035313 wound healing, spreading of epidermal cells IMP
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0090630 activation of GTPase activity IMP
 biological_processGO:1900028 negative regulation of ruffle assembly IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005096 GTPase activator activity IMP


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Apptm1b(KOMP)Wtsi/App+
Genetic Background: C57BL/6N-Apptm1b(KOMP)Wtsi/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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