ENSMUSG00000031389


Mus musculus

Features
Gene ID: ENSMUSG00000031389
  
Biological name :Arhgap4
  
Synonyms : Arhgap4 / Rho GTPase activating protein 4
  
Possible biological names infered from orthology : P98171
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A7.3
Gene start: 73891442
Gene end: 73921870
  
Corresponding Affymetrix probe sets: 10605143 (MoGene1.0st)   10605172 (MoGene1.0st)   1417118_a_at (Mouse Genome 430 2.0 Array)   1419296_at (Mouse Genome 430 2.0 Array)   1443360_x_at (Mouse Genome 430 2.0 Array)   1458190_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000110049
Ensembl peptide - ENSMUSP00000110048
Ensembl peptide - ENSMUSP00000114877
Ensembl peptide - ENSMUSP00000122794
Ensembl peptide - ENSMUSP00000121215
Ensembl peptide - ENSMUSP00000120650
Ensembl peptide - ENSMUSP00000117602
Ensembl peptide - ENSMUSP00000115193
Ensembl peptide - ENSMUSP00000067477
Ensembl peptide - ENSMUSP00000110046
Ensembl peptide - ENSMUSP00000110047
NCBI entrez gene - 171207     See in Manteia.
MGI - MGI:2159577
RefSeq - XM_011247537
RefSeq - NM_001162423
RefSeq - NM_001162424
RefSeq - NM_138630
RefSeq - XM_011247530
RefSeq - XM_011247531
RefSeq - XM_011247532
RefSeq - XM_011247533
RefSeq - XM_011247534
RefSeq - XM_011247535
RefSeq - XM_011247536
RefSeq Peptide - NP_001155896
RefSeq Peptide - NP_619536
RefSeq Peptide - NP_001155895
swissprot - D6RFT8
swissprot - B1AUY3
swissprot - B1AUY2
swissprot - F6SL55
swissprot - F6YWG4
swissprot - B1AUY1
swissprot - Q3TE27
swissprot - B1AUX5
swissprot - Q80Z68
swissprot - E9Q4R3
swissprot - E9PYS6
Ensembl - ENSMUSG00000031389
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap4aENSDARG00000039265Danio rerio
 arhgap4bENSDARG00000015003Danio rerio
 P98171ENSG00000089820Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Srgap3 / SLIT-ROBO Rho GTPase activating protein 3 / O43295*ENSMUSG0000003025745
Q91Z69 / Srgap1 / SLIT-ROBO Rho GTPase-activating protein 1 / Q7Z6B7*ENSMUSG0000002012144
Q91Z67 / Srgap2 / SLIT-ROBO Rho GTPase-activating protein 2 / P0DJJ0* / P0DMP2* / O75044* / SRGAP2B* / SRGAP2C* / SLIT-ROBO Rho GTPase activating protein 2C* / SLIT-ROBO Rho GTPase activat...ENSMUSG0000002642541
Q8BL80 / Arhgap22 / Rho GTPase activating protein 22 / Q7Z5H3*ENSMUSG0000006350613
Q3UIA2 / Arhgap17 / Rho GTPase-activating protein 17 / Q68EM7*ENSMUSG0000003076613
Q8C4V1 / Arhgap24 / Rho GTPase activating protein 24 / Q8N264*ENSMUSG0000005731512
Q5SSM3 / Arhgap44 / Rho GTPase-activating protein 44 / Q17R89*ENSMUSG0000003338912
Q8BYW1 / Arhgap25 / Rho GTPase-activating protein 25 / P42331*ENSMUSG0000003004712
P55194 / Sh3bp1 / SH3-domain binding protein 1 / Q9Y3L3* / Z83844.3*ENSMUSG0000002243611
AL592169.1 / Q9Y3L3* / SH3BP1* / Z83844.3* / SH3 domain binding protein 1*ENSMUSG0000011606910


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001060  FCH domain
 IPR001452  SH3 domain
 IPR008936  Rho GTPase activation protein
 IPR027267  AH/BAR domain superfamily
 IPR031160  F-BAR domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0010764 negative regulation of fibroblast migration IEA
 biological_processGO:0030336 negative regulation of cell migration IBA
 biological_processGO:0030517 negative regulation of axon extension IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0030426 growth cone IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0048365 Rac GTPase binding IBA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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