ENSMUSG00000022436


Mus musculus

Features
Gene ID: ENSMUSG00000022436
  
Biological name :Sh3bp1
  
Synonyms : P55194 / Sh3bp1 / SH3-domain binding protein 1
  
Possible biological names infered from orthology : Q9Y3L3 / Z83844.3
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: E1
Gene start: 78899768
Gene end: 78912051
  
Corresponding Affymetrix probe sets: 10425138 (MoGene1.0st)   1460222_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117839
Ensembl peptide - ENSMUSP00000105320
Ensembl peptide - ENSMUSP00000138598
Ensembl peptide - ENSMUSP00000138780
Ensembl peptide - ENSMUSP00000001226
Ensembl peptide - ENSMUSP00000052181
NCBI entrez gene - 20401     See in Manteia.
MGI - MGI:104603
RefSeq - XM_017316521
RefSeq - NM_001316684
RefSeq - NM_001316685
RefSeq - NM_001316686
RefSeq - NM_009164
RefSeq Peptide - NP_001303613
RefSeq Peptide - NP_001303614
RefSeq Peptide - NP_001303615
RefSeq Peptide - NP_033190
swissprot - P55194
swissprot - S4R2T6
swissprot - S4R2D3
swissprot - A2A5V1
swissprot - A2A5V3
swissprot - A2A5V2
Ensembl - ENSMUSG00000022436
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sh3bp1ENSDARG00000078119Danio rerio
 ENSGALG00000012422Gallus gallus
 Q9Y3L3ENSG00000100092Homo sapiens
 Z83844.3ENSG00000285304Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AL592169.1 / Q9Y3L3* / SH3BP1* / Z83844.3* / SH3 domain binding protein 1*ENSMUSG0000011606974
Q3UIA2 / Arhgap17 / Rho GTPase-activating protein 17 / Q68EM7*ENSMUSG0000003076641
Q5SSM3 / Arhgap44 / Rho GTPase-activating protein 44 / Q17R89*ENSMUSG0000003338940
Srgap3 / SLIT-ROBO Rho GTPase activating protein 3 / O43295*ENSMUSG0000003025718
Q91Z69 / Srgap1 / SLIT-ROBO Rho GTPase-activating protein 1 / Q7Z6B7*ENSMUSG0000002012116
Arhgap4 / Rho GTPase activating protein 4 / P98171*ENSMUSG0000003138916
Q91Z67 / Srgap2 / SLIT-ROBO Rho GTPase-activating protein 2 / P0DJJ0* / P0DMP2* / O75044* / SRGAP2B* / SRGAP2C* / SLIT-ROBO Rho GTPase activating protein 2C* / SLIT-ROBO Rho GTPase activat...ENSMUSG0000002642516
Q8C4V1 / Arhgap24 / Rho GTPase activating protein 24 / Q8N264*ENSMUSG0000005731515
Q8BL80 / Arhgap22 / Rho GTPase activating protein 22 / Q7Z5H3*ENSMUSG0000006350615
Q8BYW1 / Arhgap25 / Rho GTPase-activating protein 25 / P42331*ENSMUSG0000003004714


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR004148  BAR domain
 IPR008936  Rho GTPase activation protein
 IPR027267  AH/BAR domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006909 phagocytosis IEA
 biological_processGO:0006911 phagocytosis, engulfment ISO
 biological_processGO:0007015 actin filament organization ISS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016477 cell migration ISS
 biological_processGO:0030834 regulation of actin filament depolymerization ISO
 biological_processGO:0032956 regulation of actin cytoskeleton organization ISO
 biological_processGO:0034329 cell junction assembly ISO
 biological_processGO:0043535 regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0043547 positive regulation of GTPase activity IDA
 biological_processGO:0045198 establishment of epithelial cell apical/basal polarity ISS
 biological_processGO:0051058 negative regulation of small GTPase mediated signal transduction ISO
 biological_processGO:0071526 semaphorin-plexin signaling pathway ISO
 biological_processGO:0097178 ruffle assembly IMP
 cellular_componentGO:0000145 exocyst ISO
 cellular_componentGO:0001891 phagocytic cup ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0005912 adherens junction ISO
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0030027 lamellipodium ISO
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031252 cell leading edge ISO
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005096 GTPase activator activity ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017124 SH3 domain binding IPI
 molecular_functionGO:0030215 semaphorin receptor binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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