ENSG00000100092


Homo sapiens

Features
Gene ID: ENSG00000100092
  
Biological name :SH3BP1
  
Synonyms : Q9Y3L3 / SH3BP1 / SH3 domain binding protein 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.1
Gene start: 37634654
Gene end: 37656119
  
Corresponding Affymetrix probe sets: 213633_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000411979
Ensembl peptide - ENSP00000494748
Ensembl peptide - ENSP00000350018
NCBI entrez gene - 23616     See in Manteia.
OMIM - 617368
RefSeq - NM_018957
RefSeq Peptide - NP_061830
swissprot - Q9Y3L3
Ensembl - ENSG00000100092
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sh3bp1ENSDARG00000078119Danio rerio
 ENSGALG00000012422Gallus gallus
 AL592169.1ENSMUSG00000116069Mus musculus
 P55194ENSMUSG00000022436Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Z83844.3ENSG0000028530473
Q68EM7 / ARHGAP17 / Rho GTPase activating protein 17ENSG0000014075044
Q17R89 / ARHGAP44 / Rho GTPase activating protein 44ENSG0000000674042
O43295 / SRGAP3 / SLIT-ROBO Rho GTPase activating protein 3ENSG0000019622018
Q7Z6B7 / SRGAP1 / SLIT-ROBO Rho GTPase activating protein 1ENSG0000019693517
P98171 / ARHGAP4 / Rho GTPase activating protein 4ENSG0000008982017
O75044 / SRGAP2 / SLIT-ROBO Rho GTPase activating protein 2ENSG0000026602817
Q7Z5H3 / ARHGAP22 / Rho GTPase activating protein 22ENSG0000012880516
Q8N264 / ARHGAP24 / Rho GTPase activating protein 24ENSG0000013863916
P42331 / ARHGAP25 / Rho GTPase activating protein 25ENSG0000016321915
P0DJJ0 / SRGAP2C / SLIT-ROBO Rho GTPase activating protein 2CENSG000001719436
P0DMP2 / SRGAP2B / SLIT-ROBO Rho GTPase activating protein 2BENSG000001963693


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR004148  BAR domain
 IPR008936  Rho GTPase activation protein
 IPR027267  AH/BAR domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006909 phagocytosis IEA
 biological_processGO:0006911 phagocytosis, engulfment IMP
 biological_processGO:0007015 actin filament organization IMP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0030834 regulation of actin filament depolymerization IMP
 biological_processGO:0032956 regulation of actin cytoskeleton organization IMP
 biological_processGO:0034329 cell junction assembly IMP
 biological_processGO:0043535 regulation of blood vessel endothelial cell migration IMP
 biological_processGO:0043547 positive regulation of GTPase activity IMP
 biological_processGO:0045198 establishment of epithelial cell apical/basal polarity IMP
 biological_processGO:0051058 negative regulation of small GTPase mediated signal transduction IMP
 biological_processGO:0071526 semaphorin-plexin signaling pathway IMP
 cellular_componentGO:0000145 exocyst IDA
 cellular_componentGO:0001891 phagocytic cup IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0030027 lamellipodium IDA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031252 cell leading edge IDA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005096 GTPase activator activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0030215 semaphorin receptor binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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