ENSG00000128805


Homo sapiens

Features
Gene ID: ENSG00000128805
  
Biological name :ARHGAP22
  
Synonyms : ARHGAP22 / Q7Z5H3 / Rho GTPase activating protein 22
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q11.23
Gene start: 48446034
Gene end: 48656265
  
Corresponding Affymetrix probe sets: 1560821_at (Human Genome U133 Plus 2.0 Array)   206298_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000410054
Ensembl peptide - ENSP00000363287
Ensembl peptide - ENSP00000412461
Ensembl peptide - ENSP00000422868
Ensembl peptide - ENSP00000422663
Ensembl peptide - ENSP00000416701
Ensembl peptide - ENSP00000249601
Ensembl peptide - ENSP00000363285
NCBI entrez gene - 58504     See in Manteia.
OMIM - 610585
RefSeq - XM_017016477
RefSeq - XM_011540012
RefSeq - XM_011540013
RefSeq - XM_011540015
RefSeq - XM_017016470
RefSeq - XM_017016471
RefSeq - XM_017016472
RefSeq - XM_017016473
RefSeq - XM_017016474
RefSeq - XM_017016475
RefSeq - XM_017016476
RefSeq - NM_001256024
RefSeq - NM_001256025
RefSeq - NM_001256026
RefSeq - NM_021226
RefSeq - XM_005270014
RefSeq - XM_011540002
RefSeq - XM_011540003
RefSeq - XM_011540004
RefSeq - XM_011540005
RefSeq - XM_011540006
RefSeq - XM_011540007
RefSeq - XM_011540011
RefSeq Peptide - NP_001334667
RefSeq Peptide - NP_067049
RefSeq Peptide - NP_001242953
RefSeq Peptide - NP_001242954
RefSeq Peptide - NP_001242955
swissprot - Q7Z5H3
swissprot - D6R9V6
swissprot - A6NJ38
swissprot - D6RBJ8
swissprot - A6NHM7
Ensembl - ENSG00000128805
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARHGAP22ENSDARG00000076434Danio rerio
 ENSGALG00000006137Gallus gallus
 Q8BL80ENSMUSG00000063506Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8N264 / ARHGAP24 / Rho GTPase activating protein 24ENSG0000013863946
P42331 / ARHGAP25 / Rho GTPase activating protein 25ENSG0000016321938
O43295 / SRGAP3 / SLIT-ROBO Rho GTPase activating protein 3ENSG0000019622022
Q7Z6B7 / SRGAP1 / SLIT-ROBO Rho GTPase activating protein 1ENSG0000019693520
O75044 / SRGAP2 / SLIT-ROBO Rho GTPase activating protein 2ENSG0000026602819
P98171 / ARHGAP4 / Rho GTPase activating protein 4ENSG0000008982018
Q68EM7 / ARHGAP17 / Rho GTPase activating protein 17ENSG0000014075018
Q17R89 / ARHGAP44 / Rho GTPase activating protein 44ENSG0000000674018
Q9Y3L3 / SH3BP1 / SH3 domain binding protein 1ENSG0000010009215
Z83844.3ENSG0000028530413
P0DJJ0 / SRGAP2C / SLIT-ROBO Rho GTPase activating protein 2CENSG000001719435
P0DMP2 / SRGAP2B / SLIT-ROBO Rho GTPase activating protein 2BENSG000001963693


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005925 focal adhesion HDA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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