ENSGALG00000008378


Gallus gallus

Features
Gene ID: ENSGALG00000008378
  
Biological name :SRGAP3
  
Synonyms : SLIT-ROBO Rho GTPase activating protein 3 / SRGAP3
  
Possible biological names infered from orthology : O43295
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 19376465
Gene end: 19441407
  
Corresponding Affymetrix probe sets: Gga.1490.1.S1_at (Chicken Array)   GgaAffx.11862.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052798
Ensembl peptide - ENSGALP00000059880
Ensembl peptide - ENSGALP00000013635
Ensembl peptide - ENSGALP00000051857
NCBI entrez gene - 416115     See in Manteia.
RefSeq - XM_015293125
RefSeq - NM_001030604
RefSeq - XM_015293123
RefSeq - XM_015293124
RefSeq Peptide - NP_001025775
swissprot - Q5ZLH5
swissprot - A0A1L1RM91
swissprot - F1NVK8
swissprot - A0A1D5PJ10
Ensembl - ENSGALG00000008378
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srgap3ENSDARG00000060309Danio rerio
 O43295ENSG00000196220Homo sapiens
 Srgap3ENSMUSG00000030257Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SRGAP1 / SLIT-ROBO Rho GTPase activating protein 1 / Q7Z6B7* / Q91Z69*ENSGALG0000000982573
SRGAP2* / O75044* / P0DJJ0* / P0DMP2* / Q91Z67* / SRGAP2C* / SRGAP2B* / SLIT-ROBO Rho GTPase activating protein 2* / SLIT-ROBO Rho GTPase activating protein 2B* / SLIT-ROBO Rho GTPase activ...ENSGALG0000000081665
ARHGAP17 / Rho GTPase activating protein 17 / Q3UIA2* / Q68EM7*ENSGALG0000004121313
ARHGAP25 / rho GTPase-activating protein 25 / P42331* / Q8BYW1*ENSGALG0000003519412
P55194* / Q9Y3L3* / SH3BP1* / Z83844.3* / AL592169.1* / SH3 domain binding protein 1*ENSGALG0000001242211
Q17R89* / Q5SSM3* / ARHGAP44* / Rho GTPase activating protein 44*ENSGALG0000000131111
ARHGAP24 / Rho GTPase activating protein 24 / Q8C4V1* / Q8N264*ENSGALG0000001112410
Q7Z5H3* / Q8BL80* / ARHGAP22* / Rho GTPase activating protein 22*ENSGALG000000061378


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001060  FCH domain
 IPR001452  SH3 domain
 IPR008936  Rho GTPase activation protein
 IPR031160  F-BAR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0030336 negative regulation of cell migration IBA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0048365 Rac GTPase binding IBA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr