ENSDARG00000060309


Danio rerio

Features
Gene ID: ENSDARG00000060309
  
Biological name :srgap3
  
Synonyms : SLIT-ROBO Rho GTPase activating protein 3 / srgap3
  
Possible biological names infered from orthology : O43295
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 41554794
Gene end: 41757181
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000079269
Ensembl peptide - ENSDARP00000131286
NCBI entrez gene - 561567     See in Manteia.
swissprot - A0A0R4IAE2
swissprot - E7EYC8
ZFIN ID - ZDB-GENE-060524-4
Ensembl - ENSDARG00000060309
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SRGAP3ENSGALG00000008378Gallus gallus
 O43295ENSG00000196220Homo sapiens
 Srgap3ENSMUSG00000030257Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
srgap1a / SLIT-ROBO Rho GTPase activating protein 1a / Q7Z6B7* / Q91Z69* / SRGAP1* / SLIT-ROBO Rho GTPase activating protein 1*ENSDARG0000000746165
B0S6J3 / srgap2 / SLIT-ROBO Rho GTPase activating protein 2 / O75044* / Q91Z67* / P0DJJ0* / P0DMP2* / SRGAP2C* / SRGAP2B* / SLIT-ROBO Rho GTPase activating protein 2B* / SLIT-ROBO Rho GTPas...ENSDARG0000003216159
srgap1b / SLIT-ROBO Rho GTPase activating protein 1b / Q7Z6B7* / Q91Z69* / SRGAP1* / SLIT-ROBO Rho GTPase activating protein 1*ENSDARG0000004578956
arhgap4b / Rho GTPase activating protein 4b / P98171* / ARHGAP4* / Rho GTPase activating protein 4*ENSDARG0000001500338
arhgap4a / Rho GTPase activating protein 4a / P98171* / ARHGAP4* / Rho GTPase activating protein 4*ENSDARG0000003926533
ARHGAP22 / si:dkey-191m6.4 / Q7Z5H3* / Q8BL80* / Rho GTPase activating protein 22*ENSDARG0000007643413
si:ch211-114m9.1 / Q17R89* / ARHGAP44* / Rho GTPase activating protein 44*ENSDARG0000010242412
arhgap24 / Rho GTPase activating protein 24 / Q8C4V1* / Q8N264*ENSDARG0000010097312
arhgap17a / Rho GTPase activating protein 17a / Q68EM7* / ARHGAP17* / Rho GTPase activating protein 17*ENSDARG0000002048812
arhgap44 / Rho GTPase activating protein 44 / Q17R89* / Q5SSM3*ENSDARG0000010454911
arhgap25 / Rho GTPase activating protein 25 / P42331* / Q8BYW1*ENSDARG0000006178410
si:ch211-247j9.1ENSDARG000000792839
sh3bp1 / SH3-domain binding protein 1 / Q9Y3L3* / P55194* / Z83844.3* / AL592169.1*ENSDARG000000781199
arhgap17b / Rho GTPase activating protein 17b / Q3UIA2* / Q68EM7* / ARHGAP17* / Rho GTPase activating protein 17*ENSDARG000000622639
arhgap22 / Rho GTPase activating protein 22ENSDARG000000212556


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001060  FCH domain
 IPR001452  SH3 domain
 IPR008936  Rho GTPase activation protein
 IPR027267  AH/BAR domain superfamily
 IPR031160  F-BAR domain
 IPR035648  srGAP1/2/3, SH3 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0030336 negative regulation of cell migration IBA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0048365 Rac GTPase binding IBA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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